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fluconazole and Stevens-Johnson Syndrome

fluconazole has been researched along with Stevens-Johnson Syndrome in 9 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.

Research Excerpts

ExcerptRelevanceReference
"Fluconazole uncommonly causes Stevens-Johnson syndrome."8.86Fluconazole-associated Stevens-Johnson syndrome. ( Cohen, PR; Powell, S; Thiyanaratnam, J, 2010)
"Fluconazole uncommonly causes Stevens-Johnson syndrome."4.86Fluconazole-associated Stevens-Johnson syndrome. ( Cohen, PR; Powell, S; Thiyanaratnam, J, 2010)
"Fluconazole is a rare cause of severe cutaneous adverse drug reactions."1.35Severe cutaneous adverse drug reaction due to fluconazole. ( Brantley, JS; Kelly, BC; Kelso, RL; Lester, LJ; Petitt, MS; Wilkerson, MG, 2008)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Islam, S1
Singer, M1
Kulhanjian, JA1
Monastirli, A2
Pasmatzi, E2
Vryzaki, E1
Georgiou, S2
Tsambaos, D2
Lester, LJ1
Brantley, JS1
Kelso, RL1
Kelly, BC1
Petitt, MS1
Wilkerson, MG1
Craythorne, E1
Creamer, D1
Thiyanaratnam, J1
Cohen, PR1
Powell, S1
Sgouros, G1
Lewerenz, V1
Bruch-Gerharz, D1
Ruzicka, T1
Kruse, R1
Azón-Masoliver, A1
Vilaplana, J1
Gussenhoven, MJ1
Haak, A1
Peereboom-Wynia, JD1
van 't Wout, JW1

Reviews

2 reviews available for fluconazole and Stevens-Johnson Syndrome

ArticleYear
Toxic epidermal necrolysis in a neonate receiving fluconazole.
    Journal of perinatology : official journal of the California Perinatal Association, 2014, Volume: 34, Issue:10

    Topics: Disease Progression; Fatal Outcome; Female; Fluconazole; Humans; Infant, Newborn; Infant, Premature;

2014
Fluconazole-associated Stevens-Johnson syndrome.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:10

    Topics: Adult; Antifungal Agents; Fluconazole; Humans; Male; Stevens-Johnson Syndrome

2010

Other Studies

7 other studies available for fluconazole and Stevens-Johnson Syndrome

ArticleYear
Fluconazole-induced Stevens-Johnson syndrome in a HIV-negative patient.
    Acta dermato-venereologica, 2008, Volume: 88, Issue:5

    Topics: Anti-Inflammatory Agents; Antifungal Agents; Female; Fluconazole; Humans; Infusions, Intravenous; Me

2008
Severe cutaneous adverse drug reaction due to fluconazole.
    Journal of drugs in dermatology : JDD, 2008, Volume: 7, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antifungal Agents; Biopsy; Candidiasis, Oral; Diagnosis,

2008
Stevens-Johnson syndrome due to prophylactic fluconazole in two patients with liver failure.
    Clinical and experimental dermatology, 2009, Volume: 34, Issue:7

    Topics: Adult; Antifungal Agents; Drug Eruptions; Female; Fluconazole; Humans; Liver Failure; Stevens-Johnso

2009
Short-term and low-dose oral fluconazole treatment can cause Stevens-Johnson syndrome in HIV-negative patients.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:12

    Topics: Antifungal Agents; Fluconazole; Humans; Male; Stevens-Johnson Syndrome

2011
[Toxic epidermal necrolysis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2006, Volume: 57, Issue:4

    Topics: Administration, Oral; Administration, Topical; Adult; Antifungal Agents; Biopsy; Candidiasis, Vulvov

2006
Fluconazole-induced toxic epidermal necrolysis in a patient with human immunodeficiency virus infection.
    Dermatology (Basel, Switzerland), 1993, Volume: 187, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Candidiasis, Oral; Fluconazole; HIV Infections; Humans

1993
Stevens-Johnson syndrome after fluconazole.
    Lancet (London, England), 1991, Jul-13, Volume: 338, Issue:8759

    Topics: Adult; Candidiasis, Oral; Fluconazole; HIV Seropositivity; Homosexuality; Humans; Male; Stevens-John

1991