Page last updated: 2024-10-27

fluconazole and Sporotrichosis

fluconazole has been researched along with Sporotrichosis in 24 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Sporotrichosis: The commonest and least serious of the deep mycoses, characterized by nodular lesions of the cutaneous and subcutaneous tissues. It is caused by inhalation of contaminated dust or by infection of a wound with SPOROTHRIX.

Research Excerpts

ExcerptRelevanceReference
"Thirty patients with documented sporotrichosis were treated with 200-800 mg of fluconazole daily."9.08Treatment of lymphocutaneous and visceral sporotrichosis with fluconazole. ( Cloud, GA; Dismukes, WE; Greenfield, RA; Kauffman, CA; McKinsey, DS; Pappas, PG; Perfect, JR; Thomas, CJ, 1996)
"Eighty-eight immunocompetent patients with deep mycoses from eight countries were evaluated with the same protocol for efficacy of fluconazole monotherapy."9.07A Pan-American 5-year study of fluconazole therapy for deep mycoses in the immunocompetent host. Pan-American Study Group. ( Arathoon, EG; Borelli, D; Bran, JL; Castro, LG; Diaz, M; Franco, L; Montero-Gei, F; Negroni, R; Restrepo, A; Sampaio, SA, 1992)
"We report three cases of sporotrichosis successfully treated with oral fluconazole."7.68Successful treatment of sporotrichosis with oral fluconazole: a report of three cases. ( Belda Júnior, W; Castro, LG; Cucé, LC; Sampaio, SA; Stevens, DA, 1993)
" Itraconazole was superior to fluconazole in candidosis, cryptococcosis, sporotrichosis and aspergillosis, and to amphotericin B and to flucytosine in candidosis, cryptococcosis and aspergillosis."7.68In vitro antifungal spectrum of itraconazole and treatment of systemic mycoses with old and new antimycotic agents. ( Van Cutsem, J, 1992)
"Cutaneous sporotrichosis is clinically divided into two main types: lymphocutaneous and fixed plaque type."5.31Case report. An unusual case of cutaneous sporotrichosis and its response to weekly fluconazole. ( Akhyani, M; Arad, S; Ataii, L; Daneshpazhooh, M; Ghodsi, SZ; Naraghi, Z; Shams, S, 2000)
"Thirty patients with documented sporotrichosis were treated with 200-800 mg of fluconazole daily."5.08Treatment of lymphocutaneous and visceral sporotrichosis with fluconazole. ( Cloud, GA; Dismukes, WE; Greenfield, RA; Kauffman, CA; McKinsey, DS; Pappas, PG; Perfect, JR; Thomas, CJ, 1996)
"Eighty-eight immunocompetent patients with deep mycoses from eight countries were evaluated with the same protocol for efficacy of fluconazole monotherapy."5.07A Pan-American 5-year study of fluconazole therapy for deep mycoses in the immunocompetent host. Pan-American Study Group. ( Arathoon, EG; Borelli, D; Bran, JL; Castro, LG; Diaz, M; Franco, L; Montero-Gei, F; Negroni, R; Restrepo, A; Sampaio, SA, 1992)
"We report three cases of sporotrichosis successfully treated with oral fluconazole."3.68Successful treatment of sporotrichosis with oral fluconazole: a report of three cases. ( Belda Júnior, W; Castro, LG; Cucé, LC; Sampaio, SA; Stevens, DA, 1993)
" Itraconazole was superior to fluconazole in candidosis, cryptococcosis, sporotrichosis and aspergillosis, and to amphotericin B and to flucytosine in candidosis, cryptococcosis and aspergillosis."3.68In vitro antifungal spectrum of itraconazole and treatment of systemic mycoses with old and new antimycotic agents. ( Van Cutsem, J, 1992)
"Feline sporotrichosis has been reported in Malaysia since the 1990's."2.55The Current Status of Feline Sporotrichosis in Malaysia. ( Siew, HH, 2017)
"Pulmonary sporotrichosis is rare and responds poorly to treatment."1.33Pulmonary Sporothrix schenckii infection in a HIV positive child. ( Behets, F; Callens, SF; Colebunders, R; Kitetele, F; Lelo, P; Lukun, P; Van Rie, A, 2006)
"Cutaneous sporotrichosis is clinically divided into two main types: lymphocutaneous and fixed plaque type."1.31Case report. An unusual case of cutaneous sporotrichosis and its response to weekly fluconazole. ( Akhyani, M; Arad, S; Ataii, L; Daneshpazhooh, M; Ghodsi, SZ; Naraghi, Z; Shams, S, 2000)
"Medical treatments for chromoblastomycosis has been disappointing, while lymphocutaneous sporotrichosis usually responds well to iodides."1.29Successful treatment of subcutaneous mycoses with fluconazole: a report of two cases. ( Cheng, NC; Kuo, BI; Lee, WS; Liu, CE; Liu, CY; Yang, SP, 1995)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (45.83)18.2507
2000's8 (33.33)29.6817
2010's3 (12.50)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Alvarado-Ramírez, E1
Torres-Rodríguez, JM1
Marimon, R1
Serena, C1
Gené, J1
Cano, J1
Guarro, J1
Indoung, S1
Chanchayanon, B1
Chaisut, M1
Buapeth, KO1
Morteh, R1
Jantrakajorn, S1
Song, Y1
Li, S1
Shi, Y1
Zhao, L1
Cui, Y2
Yao, L1
Zhen, Y1
Chen, R1
Siew, HH1
Ramírez Soto, MC1
Landell, MF1
Stopiglia, CD1
Billodre, RG1
Heidrich, D1
Sorrentino, JM1
Vainstein, MH1
Scroferneker, ML1
Valente, P1
Hampton, DE1
Adesina, A1
Chodosh, J1
Sharma, NL2
Mahajan, VK2
Verma, N1
Thakur, S1
Kimyai-Asadi, A1
Jih, MH1
Began, DM1
Mully, TW1
Shupack, JL1
Kamino, H1
Sharma, RC1
Gupta, ML1
Garg, G1
Kanga, AK1
Callens, SF1
Kitetele, F1
Lukun, P1
Lelo, P1
Van Rie, A1
Behets, F1
Colebunders, R1
Donabedian, H1
O'Donnell, E1
Olszewski, C1
MacArthur, RD1
Budd, N1
Castro, LG2
Belda Júnior, W1
Cucé, LC1
Sampaio, SA2
Stevens, DA1
Kauffman, CA1
Pappas, PG1
McKinsey, DS1
Greenfield, RA1
Perfect, JR1
Cloud, GA1
Thomas, CJ1
Dismukes, WE1
Yang, SP1
Liu, CY1
Cheng, NC1
Lee, WS1
Liu, CE1
Kuo, BI1
Wu, S1
Guo, N1
Hou, Y1
Vieira-Dias, D1
Sena, CM1
Oréfice, F1
Tanure, MA1
Hamdan, JS1
Goldani, LZ1
Aquino, VR1
Dargél, AA1
Ghodsi, SZ1
Shams, S1
Naraghi, Z1
Daneshpazhooh, M1
Akhyani, M1
Arad, S1
Ataii, L1
Van Cutsem, J1
Penn, CC1
Goldstein, E1
Bartholomew, WR1
Diaz, M1
Negroni, R1
Montero-Gei, F1
Borelli, D1
Restrepo, A1
Franco, L1
Bran, JL1
Arathoon, EG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00004938]Phase 230 participants Interventional1996-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for fluconazole and Sporotrichosis

ArticleYear
The Current Status of Feline Sporotrichosis in Malaysia.
    Medical mycology journal, 2017, Volume: 58, Issue:3

    Topics: Amphotericin B; Animals; Antifungal Agents; Cat Diseases; Cats; Drug Resistance, Fungal; Fluconazole

2017
Sporotrichosis in the Ocular Adnexa: 21 Cases in an Endemic Area in Peru and Review of the Literature.
    American journal of ophthalmology, 2016, Volume: 162

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Child; Child, Preschool; Conjunctival Diseases; Dacryocy

2016
Ocular and concomitant cutaneous sporotrichosis.
    Mycoses, 1997, Volume: 40, Issue:5-6

    Topics: Amphotericin B; Anterior Chamber; Brazil; Child; Eye Infections, Fungal; Female; Fluconazole; Humans

1997

Trials

2 trials available for fluconazole and Sporotrichosis

ArticleYear
Treatment of lymphocutaneous and visceral sporotrichosis with fluconazole.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:1

    Topics: Adult; Antifungal Agents; Dose-Response Relationship, Drug; Female; Fluconazole; Humans; Male; Middl

1996
A Pan-American 5-year study of fluconazole therapy for deep mycoses in the immunocompetent host. Pan-American Study Group.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 14 Suppl 1

    Topics: Adolescent; Adult; Aged; Chromoblastomycosis; Coccidioidomycosis; Female; Fluconazole; Fungi; Histop

1992

Other Studies

19 other studies available for fluconazole and Sporotrichosis

ArticleYear
In vitro susceptibility of Sporothrix schenckii to six antifungal agents determined using three different methods.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Amphotericin B; Antifungal Agents; Fluconazole; Flucytosine; Humans; In Vitro Techniques; Itraconazo

2007
In vitro antifungal susceptibilities of five species of sporothrix.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Animals; Antifungal Agents; Drug Resistance, Fungal; Humans; Microbial Sensitivity Tests; Species Sp

2008
Feline sporotrichosis caused by Sporothrix schenckii sensu stricto in Southern Thailand: phenotypic characterization, molecular identification, and antifungal susceptibility.
    Medical mycology, 2022, Sep-30, Volume: 60, Issue:9

    Topics: Amphotericin B; Animals; Antifungal Agents; Calmodulin; Cat Diseases; Cats; Fluconazole; Itraconazol

2022
In vitro antifungal susceptibility of Sporothrix globosa isolates from Jilin Province, northeastern China: comparison of yeast and mycelial phases.
    Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2021, Volume: 52, Issue:1

    Topics: Amphotericin B; Antifungal Agents; China; Fluconazole; Humans; Itraconazole; Microbial Sensitivity T

2021
Evaluation of the origin of a sample of Sporothrix schenckii that caused contamination of a researcher in Southern Brazil.
    Mycopathologia, 2011, Volume: 171, Issue:3

    Topics: Brazil; Fluconazole; Humans; Ketoconazole; Laboratories; Male; Microbial Sensitivity Tests; Potassiu

2011
Conjunctival sporotrichosis in the absence of antecedent trauma.
    Cornea, 2002, Volume: 21, Issue:8

    Topics: Adult; Antifungal Agents; Conjunctiva; Conjunctivitis; Diagnosis, Differential; Eye Infections, Fung

2002
Cutaneous sporotrichosis: an unusual clinico-pathologic and therapeutic presentation.
    Mycoses, 2003, Volume: 46, Issue:11-12

    Topics: Adult; Antifungal Agents; Facial Dermatoses; Female; Fluconazole; Humans; Potassium Iodide; Sporothr

2003
A 63-year-old man with chronic penile ulcers.
    Archives of dermatology, 2003, Volume: 139, Issue:12

    Topics: Antifungal Agents; Biopsy; Fluconazole; Humans; Male; Middle Aged; Penile Diseases; Skin; Sporotrich

2003
Cutaneous sporotrichosis in Himachal Pradesh, India.
    Mycoses, 2005, Volume: 48, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Child; Female; Fluconazole; Humans; I

2005
Pulmonary Sporothrix schenckii infection in a HIV positive child.
    Journal of tropical pediatrics, 2006, Volume: 52, Issue:2

    Topics: Antifungal Agents; Child; Democratic Republic of the Congo; Fluconazole; HIV Seropositivity; Humans;

2006
Disseminated cutaneous and meningeal sporotrichosis in an AIDS patient.
    Diagnostic microbiology and infectious disease, 1994, Volume: 18, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Fluconazole; Humans; Male; Meningoencephalitis; Sporot

1994
Successful treatment of sporotrichosis with oral fluconazole: a report of three cases.
    The British journal of dermatology, 1993, Volume: 128, Issue:3

    Topics: Administration, Oral; Adult; Fluconazole; Foot Dermatoses; Hand Dermatoses; Humans; Male; Middle Age

1993
Successful treatment of subcutaneous mycoses with fluconazole: a report of two cases.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1995, Volume: 56, Issue:6

    Topics: Adult; Aged; Antifungal Agents; Chromoblastomycosis; Fluconazole; Humans; Male; Sporotrichosis

1995
Effects of systemic fluconazole therapy on in vitro adhesion of Candida albicans to buccal epithelial cells and changes of the cell surface proteins of the epithelial cells.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1996, Volume: 11, Issue:1

    Topics: Adult; Antifungal Agents; Candida albicans; Candidiasis, Oral; Epithelium; Female; Fluconazole; Huma

1996
Systemic antifungal drugs.
    The Medical letter on drugs and therapeutics, 1997, Sep-12, Volume: 39, Issue:1009

    Topics: Amphotericin B; Anorexia; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidom

1997
Disseminated cutaneous sporotrichosis in an AIDS patient receiving maintenance therapy with fluconazole for previous cryptococcal meningitis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1999, Volume: 28, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amphotericin B; Female; Fluconazole; Humans; Meningitis,

1999
Case report. An unusual case of cutaneous sporotrichosis and its response to weekly fluconazole.
    Mycoses, 2000, Volume: 43, Issue:1-2

    Topics: Aged; Antifungal Agents; Drug Administration Schedule; Female; Fluconazole; Humans; Sporotrichosis;

2000
In vitro antifungal spectrum of itraconazole and treatment of systemic mycoses with old and new antimycotic agents.
    Chemotherapy, 1992, Volume: 38 Suppl 1

    Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Cryptococcosis; Drug Therapy

1992
Sporothrix schenckii meningitis in a patient with AIDS.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 15, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Dermatomycoses; Fluconazole; Humans; M

1992