fluconazole has been researched along with Splenic Diseases in 17 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Splenic Diseases: Diseases involving the SPLEEN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the efficacy of fluconazole against chronic disseminated candidiasis (hepatosplenic candidiasis) in patients with leukemia in whom amphotericin B treatment had failed." | 9.07 | Fluconazole therapy for chronic disseminated candidiasis in patients with leukemia and prior amphotericin B therapy. ( Anaissie, E; Barnett, K; Bodey, GP; Bow, E; David, C; Defelice, R; Downs, N; File, T; Kantarjian, H; Karam, G, 1991) |
| " We report a case of hepatosplenic candidiasis in a patient with acute myelogenous leukemia who had clinical and radiographic improvement during fluconazole therapy." | 7.68 | Fluconazole in the treatment of hepatosplenic candidiasis. ( Adelman, HM; Altus, P; Flannery, MT; Saba, H; Simmons, DB; Wallach, PM, 1992) |
| "To determine if fluconazole is effective treatment for hepatosplenic candidiasis that has not resolved with amphotericin B and flucytosine treatment." | 7.68 | Hepatosplenic candidiasis: successful treatment with fluconazole. ( Bradley, SF; Kauffman, CA; Ross, SC; Weber, DR, 1991) |
| "To study the efficacy of fluconazole against chronic disseminated candidiasis (hepatosplenic candidiasis) in patients with leukemia in whom amphotericin B treatment had failed." | 5.07 | Fluconazole therapy for chronic disseminated candidiasis in patients with leukemia and prior amphotericin B therapy. ( Anaissie, E; Barnett, K; Bodey, GP; Bow, E; David, C; Defelice, R; Downs, N; File, T; Kantarjian, H; Karam, G, 1991) |
| "Two pediatric leukemic patients with hepatosplenic candidiasis during multidrug antileukemic chemotherapy successfully underwent bone marrow transplantation (BMT) after aggressive antifungal chemotherapy employing fluconazole and amphotericin B with or without splenectomy." | 3.69 | Successful peritransplant therapy in children with active hepatosplenic candidiasis. ( Ichihara, T; Katayama, K; Koizumi, S; Konishi, M; Maekawa, S; Seki, H; Tamaru, Y; Taniguchi, N; Yamagami, M, 1994) |
| " We report a case of hepatosplenic candidiasis in a patient with acute myelogenous leukemia who had clinical and radiographic improvement during fluconazole therapy." | 3.68 | Fluconazole in the treatment of hepatosplenic candidiasis. ( Adelman, HM; Altus, P; Flannery, MT; Saba, H; Simmons, DB; Wallach, PM, 1992) |
| "To determine if fluconazole is effective treatment for hepatosplenic candidiasis that has not resolved with amphotericin B and flucytosine treatment." | 3.68 | Hepatosplenic candidiasis: successful treatment with fluconazole. ( Bradley, SF; Kauffman, CA; Ross, SC; Weber, DR, 1991) |
| "We report a patient with acute myeloid leukemia who developed HSC during post-remission consolidation chemotherapy and was treated with a prolonged course of caspofungin followed by fluconazole." | 2.45 | Successful intensive chemotherapy followed by autologous hematopoietic cell transplantation in a patient with acute myeloid leukemia and hepatosplenic candidiasis: case report and review of literature. ( Chia, HY; Koh, LP; Liu, TC; Poon, LM; Tan, LK, 2009) |
| "Focal hepatosplenic candidiasis has been increasingly recognized as a variant of disseminated candidiasis in immunocompromised patients." | 2.40 | Candida splenic abscess in the absence of obvious immunodeficiency. ( Howden, CW; Kapur, A; Vasudeva, R, 1997) |
| "This syndrome has a favorable prognosis." | 1.29 | A radiologic syndrome after high dose chemotherapy and autologous bone marrow transplantation, with clinical and pathologic features of systemic candidiasis. ( Hussein, A; Meisenberg, B; Mudad, R; Paulson, EK; Peters, WP; Ross, M; Vredenburgh, J, 1994) |
| "Hepatosplenic candidiasis is increasingly observed in patients with a haematological malignancy who have received chemotherapy." | 1.29 | [Hepatosplenic candidiasis in patients treated for hemato-oncological disorders]. ( Huijgens, PC; Sibinga, L; Zweegman, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (64.71) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poon, LM | 1 |
| Chia, HY | 1 |
| Tan, LK | 1 |
| Liu, TC | 1 |
| Koh, LP | 1 |
| Teyton, P | 1 |
| Baillet, G | 1 |
| Hindié, E | 1 |
| Filmont, JE | 1 |
| Sarandi, F | 1 |
| Toubert, ME | 1 |
| Moretti, JL | 1 |
| Beam, E | 1 |
| Mansfield, AS | 1 |
| Thompson, CA | 1 |
| Medlicott, SA | 1 |
| Cox, H | 1 |
| Dupre, M | 1 |
| Lategan, J | 1 |
| Auer, I | 1 |
| Hollaar, G | 1 |
| Debru, E | 1 |
| Conly, J | 1 |
| Mudad, R | 1 |
| Vredenburgh, J | 1 |
| Paulson, EK | 1 |
| Ross, M | 1 |
| Meisenberg, B | 1 |
| Hussein, A | 1 |
| Peters, WP | 1 |
| Chubachi, A | 1 |
| Miura, I | 1 |
| Ohshima, A | 1 |
| Nishinari, T | 1 |
| Nimura, T | 1 |
| Niitsu, H | 1 |
| Miura, AB | 1 |
| Katayama, K | 1 |
| Koizumi, S | 1 |
| Yamagami, M | 1 |
| Tamaru, Y | 1 |
| Ichihara, T | 1 |
| Konishi, M | 1 |
| Maekawa, S | 1 |
| Seki, H | 1 |
| Taniguchi, N | 1 |
| Zweegman, S | 1 |
| Sibinga, L | 1 |
| Huijgens, PC | 1 |
| Kapur, A | 1 |
| Vasudeva, R | 1 |
| Howden, CW | 1 |
| Colović, M | 1 |
| Lazarević, V | 1 |
| Colović, R | 1 |
| Janković, G | 1 |
| Suvajdzić, N | 1 |
| Bogdanović, A | 1 |
| Bila, J | 1 |
| Gangadharan, VP | 1 |
| Sasidharan, K | 1 |
| Preetha, S | 1 |
| Chithrathara, K | 1 |
| Rókusz, L | 1 |
| Liptay, L | 1 |
| Kádár, K | 1 |
| Flannery, MT | 1 |
| Simmons, DB | 1 |
| Saba, H | 1 |
| Altus, P | 1 |
| Wallach, PM | 1 |
| Adelman, HM | 1 |
| Kauffman, CA | 1 |
| Bradley, SF | 1 |
| Ross, SC | 1 |
| Weber, DR | 1 |
| Anaissie, E | 1 |
| Bodey, GP | 1 |
| Kantarjian, H | 1 |
| David, C | 1 |
| Barnett, K | 1 |
| Bow, E | 1 |
| Defelice, R | 1 |
| Downs, N | 1 |
| File, T | 1 |
| Karam, G | 1 |
| Jakab, K | 2 |
| Kelemen, E | 2 |
| Prinz, G | 1 |
| Török, I | 2 |
| Váradi, G | 1 |
2 reviews available for fluconazole and Splenic Diseases
| Article | Year |
|---|---|
Successful intensive chemotherapy followed by autologous hematopoietic cell transplantation in a patient with acute myeloid leukemia and hepatosplenic candidiasis: case report and review of literature.
Topics: Adult; Antifungal Agents; Candida tropicalis; Candidiasis; Caspofungin; Cytarabine; Echinocandins; F | 2009 |
Candida splenic abscess in the absence of obvious immunodeficiency.
Topics: Abscess; Antifungal Agents; Candidiasis; Diabetes Mellitus, Type 1; Drainage; Female; Fluconazole; G | 1997 |
1 trial available for fluconazole and Splenic Diseases
| Article | Year |
|---|---|
Fluconazole therapy for chronic disseminated candidiasis in patients with leukemia and prior amphotericin B therapy.
Topics: Adult; Aged; Amphotericin B; Candidiasis; Child, Preschool; Chronic Disease; Female; Fluconazole; Hu | 1991 |
14 other studies available for fluconazole and Splenic Diseases
| Article | Year |
|---|---|
Hepatosplenic candidiasis imaged with F-18 FDG PET/CT.
Topics: Antifungal Agents; Candidiasis; Fluconazole; Fluorodeoxyglucose F18; Humans; Leukemia, Myeloid, Acut | 2009 |
68-year-old man with neutropenic fever and upper extremity hematoma.
Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antifungal Agents; Antineoplastic Combined Chemotherap | 2012 |
Systemic illnesses unexpectedly presenting as acute appendicitis: case studies.
Topics: Acute Disease; Adult; Amphotericin B; Antifungal Agents; Appendicitis; Candidiasis; Female; Fluconaz | 2008 |
A radiologic syndrome after high dose chemotherapy and autologous bone marrow transplantation, with clinical and pathologic features of systemic candidiasis.
Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Mar | 1994 |
Risk factors for hepatosplenic abscesses in patients with acute leukemia receiving empiric azole treatment.
Topics: Abscess; Acute Disease; Adolescent; Adult; Aged; Candidiasis; Female; Fever; Fluconazole; Humans; Le | 1994 |
Successful peritransplant therapy in children with active hepatosplenic candidiasis.
Topics: Amphotericin B; Bone Marrow Transplantation; Candidiasis; Child, Preschool; Female; Fluconazole; Hum | 1994 |
[Hepatosplenic candidiasis in patients treated for hemato-oncological disorders].
Topics: Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Candidiasis; Drug Therapy, Combinati | 1994 |
Hepatosplenic candidiasis after neutropenic phase of acute leukaemia.
Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Candidiasi | 1999 |
Chronic systemic (hepatosplenic) candidiasis in a patient with granulocytic sarcoma.
Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Candidiasi | 2000 |
Successful treatment of chronic disseminated candidiasis with fluconazole and a granulocyte-macrophage colony-stimulating factor combination.
Topics: Adult; Antifungal Agents; Candidiasis; Drug Therapy, Combination; Female; Fluconazole; Granulocyte-M | 2001 |
Fluconazole in the treatment of hepatosplenic candidiasis.
Topics: Candidiasis; Fluconazole; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Liver Diseases; | 1992 |
Hepatosplenic candidiasis: successful treatment with fluconazole.
Topics: Acute Disease; Adolescent; Adult; Amphotericin B; Candidiasis; Child; Child, Preschool; Fluconazole; | 1991 |
Amphotericin-resistant invasive hepatosplenic candidiasis controlled by fluconazole.
Topics: Adult; Amphotericin B; Candida albicans; Candidiasis; Drug Administration Schedule; Drug Resistance; | 1990 |
[Amphotericin B resistant severe hepato-splenic candidiasis, responding to fluconazole, in a patient following bone marrow transplantation].
Topics: Adult; Amphotericin B; Bone Marrow Transplantation; Candidiasis; Female; Fluconazole; Humans; Leukem | 1991 |