fluconazole has been researched along with Shock, Septic in 11 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To demonstrate whether fluconazole reduces multiple organ failure and mortality in early septic shock (<24 hrs)." | 5.10 | Fluconazole improves survival in septic shock: a randomized double-blind prospective study. ( Al Omar, NF; Jacobs, S; Price Evans, DA; Tariq, M, 2003) |
| "Candida krusei is inherently resistant to fluconazole and is emerging as a frequent cause of fungemia in patients with hematologic malignant neoplasms." | 3.70 | Candida krusei fungemia. An escalating serious infection in immunocompromised patients. ( Abbas, J; Abi-Said, D; Bodey, GP; Girgawy, E; Hachem, R; Hanna, HA; Mardani, M; Raad, I; Whimbey, E, 2000) |
| "Most patients with sepsis or septic shock from a urinary source have complicated urinary tract infection." | 2.49 | Urinary tract infection. ( Nicolle, LE, 2013) |
| "Patients aged 18-99 years with septic shock presenting to Barnes-Jewish Hospital, St." | 1.40 | Effects of empiric antifungal therapy for septic shock on time to appropriate therapy for Candida infection: a pilot study. ( Arnold, H; Hampton, N; Juang, P; Kollef, M; McKenzie, M; Micek, ST; Scolarici, M, 2014) |
| "Zygomycosis is an infection caused by opportunistic fungi of the Zygomycetes class, specifically those from the Mucorales and Entomophthorales orders." | 1.36 | Meningoencephalitis caused by a zygomycete fungus (Basidiobolus) associated with septic shock in an immunocompetent patient: 1-year follow-up after treatment. ( Alkmim-Teixeira, GC; Auxiliadora-Martins, M; Basile-Filho, A; Bellissimo-Rodrigues, F; Carlotti, CG; Machado-Viana, J; Martins-Filho, OA; Nicolini, EA, 2010) |
| "Fluconazole is an antifungal medication that has been reported to cause prolongation of the QT interval and Torsades de Pointes (TdP) ventricular tachycardia in adults." | 1.35 | Torsades de Pointes ventricular tachycardia in a pediatric patient treated with fluconazole. ( Esch, JJ; Kantoch, MJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Choo, KS | 1 |
| Yew, J | 1 |
| Tan, EJH | 1 |
| Puar, THK | 1 |
| Jandhyala, D | 1 |
| Tan, EM | 1 |
| Stahr, DC | 1 |
| Sohail, MR | 1 |
| Nicolle, LE | 1 |
| Micek, ST | 1 |
| Arnold, H | 1 |
| Juang, P | 1 |
| Hampton, N | 1 |
| McKenzie, M | 1 |
| Scolarici, M | 1 |
| Kollef, M | 1 |
| Krashin, E | 1 |
| Lishner, M | 1 |
| Chowers, M | 1 |
| Reisfeld, S | 1 |
| Dabas, Y | 1 |
| Bakhshi, S | 1 |
| Xess, I | 1 |
| Auxiliadora-Martins, M | 1 |
| Alkmim-Teixeira, GC | 1 |
| Machado-Viana, J | 1 |
| Nicolini, EA | 1 |
| Martins-Filho, OA | 1 |
| Bellissimo-Rodrigues, F | 1 |
| Carlotti, CG | 1 |
| Basile-Filho, A | 1 |
| Jacobs, S | 1 |
| Price Evans, DA | 1 |
| Tariq, M | 1 |
| Al Omar, NF | 1 |
| Khan, HA | 1 |
| Esch, JJ | 1 |
| Kantoch, MJ | 1 |
| Abbas, J | 1 |
| Bodey, GP | 1 |
| Hanna, HA | 1 |
| Mardani, M | 1 |
| Girgawy, E | 1 |
| Abi-Said, D | 1 |
| Whimbey, E | 1 |
| Hachem, R | 1 |
| Raad, I | 1 |
3 reviews available for fluconazole and Shock, Septic
| Article | Year |
|---|---|
Case Report: Hypercalcemia as a manifestation of acute adrenal crisis precipitated by fluconazole use, and a review of the literature.
Topics: Adrenal Insufficiency; Aged; Fluconazole; Humans; Hydrocortisone; Hypercalcemia; Male; Shock, Septic | 2023 |
Urinary tract infection.
Topics: Acute Disease; Aminoglycosides; Amphotericin B; Anti-Infective Agents; Antifungal Agents; Catheters, | 2013 |
Fatal Cases of Bloodstream Infection by Fusarium solani and Review of Published Literature.
Topics: Adolescent; Aged; Amphotericin B; Antifungal Agents; Base Sequence; DNA, Intergenic; Fluconazole; Fu | 2016 |
1 trial available for fluconazole and Shock, Septic
| Article | Year |
|---|---|
Fluconazole improves survival in septic shock: a randomized double-blind prospective study.
Topics: Adult; Aged; Antifungal Agents; Cross Infection; Double-Blind Method; Female; Fluconazole; Hospital | 2003 |
7 other studies available for fluconazole and Shock, Septic
| Article | Year |
|---|---|
Disseminated
Topics: Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Ciprofloxacin; Cryptococcosis; Cryptococcu | 2019 |
Effects of empiric antifungal therapy for septic shock on time to appropriate therapy for Candida infection: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Candidemia; Colony Count, Microbial; Controlled B | 2014 |
Candida albicans in peritoneal fluid in a patient with hepatic encephalopathy.
Topics: Administration, Intravenous; Anti-Bacterial Agents; Antifungal Agents; Ascites; Ascitic Fluid; beta- | 2014 |
Meningoencephalitis caused by a zygomycete fungus (Basidiobolus) associated with septic shock in an immunocompetent patient: 1-year follow-up after treatment.
Topics: Aged; Amphotericin B; Antifungal Agents; Entomophthorales; Fluconazole; Follow-Up Studies; Humans; I | 2010 |
Effect of fluconazole on phagocytic response of polymorphonuclear leukocytes in a rat model of acute sepsis.
Topics: Analysis of Variance; Animals; Antifungal Agents; Disease Models, Animal; Dose-Response Relationship | 2005 |
Torsades de Pointes ventricular tachycardia in a pediatric patient treated with fluconazole.
Topics: Antifungal Agents; Candidiasis; Child; Electrocardiography; Fluconazole; Heart Conduction System; Hu | 2008 |
Candida krusei fungemia. An escalating serious infection in immunocompromised patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Antineoplastic Agents | 2000 |