fluconazole has been researched along with Premature Birth in 9 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Premature Birth: CHILDBIRTH before 37 weeks of PREGNANCY (259 days from the first day of the mother's last menstrual period, or 245 days after FERTILIZATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "This observational pre-post cohort study was performed in preterm infants with a birth weight of < 1,000 g who were given prophylactic fluconazole starting on the first postnatal day at a dose of 3 mg/kg twice a week." | 7.80 | Efficacy of prophylactic fluconazole therapy in decreasing the incidence of Candida infections in extremely low birth weight preterm infants. ( Buyukkale, G; Cetinkaya, M; Ercan, TE; Kavuncuoglu, S; Mete, F; Saglam, OK, 2014) |
| "Published results from several recent randomized controlled trials currently show a level I evidence that fluconazole for prevention of fungal sepsis, probiotics for prevention of necrotizing enterocolitis, and bovine lactoferrin for prevention of bacterial sepsis should be considered as preventive strategies in NICUs." | 4.87 | Lactoferrin for prevention of neonatal infections. ( Manzoni, P; Mostert, M; Stronati, M, 2011) |
| "This observational pre-post cohort study was performed in preterm infants with a birth weight of < 1,000 g who were given prophylactic fluconazole starting on the first postnatal day at a dose of 3 mg/kg twice a week." | 3.80 | Efficacy of prophylactic fluconazole therapy in decreasing the incidence of Candida infections in extremely low birth weight preterm infants. ( Buyukkale, G; Cetinkaya, M; Ercan, TE; Kavuncuoglu, S; Mete, F; Saglam, OK, 2014) |
| "Intra-amniotic Candida infection is associated with preterm rupture of membranes, preterm labor, severe neonatal infection, and fetal death." | 1.39 | Intra-amniotic fluconazole therapy for Candida albicans intra-amniotic infection. ( Bean, LM; Beiswenger, TR; Dobak, WJ; Jackson, JR; Thorp, JA, 2013) |
| " The occurrence of LAMB-attributable renal toxicity was investigated; infants withdrawn from treatment for development of adverse effects or toxicity were identified." | 1.38 | Liposomal amphotericin B does not induce nephrotoxicity or renal function impairment in premature neonates. ( Antonucci, R; Fanos, V; Farina, D; Franco, C; Galletto, P; Gallo, E; Manzoni, P; Rizzollo, S, 2012) |
| "Fluconazole was administered in 3 mg/kg doses, given every 48 hours, starting on day 3 of life, for a period of 6 weeks." | 1.36 | Impact of routine fluconazole prophylaxis for premature infants with birth weights of less than 1250 grams in a developing country. ( Espinosa, M; Moreno, MT; Rueda, K; Sáez-Llorens, X, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cetinkaya, M | 1 |
| Ercan, TE | 1 |
| Saglam, OK | 1 |
| Buyukkale, G | 1 |
| Kavuncuoglu, S | 1 |
| Mete, F | 1 |
| Kaufman, DA | 2 |
| Rueda, K | 1 |
| Moreno, MT | 1 |
| Espinosa, M | 1 |
| Sáez-Llorens, X | 1 |
| Manzoni, P | 3 |
| Mostert, M | 2 |
| Stronati, M | 2 |
| Latino, MA | 1 |
| Pugni, L | 1 |
| Stolfi, I | 1 |
| Decembrino, L | 1 |
| Vagnarelli, F | 1 |
| Corona, G | 1 |
| Tridapalli, E | 1 |
| Vetrano, G | 1 |
| Memo, L | 1 |
| Priolo, C | 1 |
| Galletto, P | 2 |
| Giovannozzi, C | 1 |
| Gallo, E | 2 |
| Pedicino, R | 1 |
| Barberi, I | 1 |
| Faldella, G | 1 |
| Mosca, F | 1 |
| Saia, OS | 1 |
| Bollani, L | 1 |
| Maragliano, R | 1 |
| Ruffinazzi, G | 1 |
| Tzialla, C | 1 |
| Rizzollo, S | 2 |
| Farina, D | 2 |
| Benjamin, DK | 1 |
| Smith, PB | 1 |
| Jacqz-Aigrain, E | 1 |
| Kaguelidou, F | 1 |
| Cohen-Wolkowiez, M | 1 |
| Franco, C | 1 |
| Antonucci, R | 1 |
| Fanos, V | 1 |
| Bean, LM | 1 |
| Jackson, JR | 1 |
| Dobak, WJ | 1 |
| Beiswenger, TR | 1 |
| Thorp, JA | 1 |
| Battin, MR | 1 |
| Wilson, EM | 1 |
2 reviews available for fluconazole and Premature Birth
| Article | Year |
|---|---|
Lactoferrin for prevention of neonatal infections.
Topics: Anti-Infective Agents; Chemoprevention; Enterocolitis, Necrotizing; Fluconazole; Humans; Infant, New | 2011 |
"Getting to Zero": preventing invasive Candida infections and eliminating infection-related mortality and morbidity in extremely preterm infants.
Topics: Antifungal Agents; Candidiasis, Invasive; Fluconazole; Humans; Infant, Newborn; Infant, Premature, D | 2012 |
1 trial available for fluconazole and Premature Birth
| Article | Year |
|---|---|
Clinical characteristics and response to prophylactic fluconazole of preterm VLBW neonates with baseline and acquired fungal colonisation in NICU: data from a multicentre RCT.
Topics: Antifungal Agents; Candida; Candidiasis, Invasive; Female; Fluconazole; Humans; Infant; Infant, Newb | 2012 |
6 other studies available for fluconazole and Premature Birth
| Article | Year |
|---|---|
Efficacy of prophylactic fluconazole therapy in decreasing the incidence of Candida infections in extremely low birth weight preterm infants.
Topics: Antifungal Agents; Birth Weight; Candidiasis, Invasive; Female; Fluconazole; Gestational Age; Humans | 2014 |
Prevention of invasive Candida infections in preterm infants: the time is now.
Topics: Antifungal Agents; Candidiasis; Fluconazole; Fungemia; Gestational Age; Humans; Infant, Newborn; Inf | 2008 |
Impact of routine fluconazole prophylaxis for premature infants with birth weights of less than 1250 grams in a developing country.
Topics: Antibiotic Prophylaxis; Antifungal Agents; Candidiasis; Chi-Square Distribution; Cohort Studies; Dev | 2010 |
Liposomal amphotericin B does not induce nephrotoxicity or renal function impairment in premature neonates.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Cohort Studies; Creatinine; Fluconazole; Humans; Hyp | 2012 |
Intra-amniotic fluconazole therapy for Candida albicans intra-amniotic infection.
Topics: Abruptio Placentae; Adult; Amnion; Anti-Bacterial Agents; Antifungal Agents; Candidiasis; Cesarean S | 2013 |
Trichophyton rubrum skin infection in two premature infants.
Topics: Antifungal Agents; Dermatomycoses; Female; Fluconazole; Humans; Infant, Newborn; New Zealand; Premat | 2005 |