Page last updated: 2024-10-27

fluconazole and Pregnancy

fluconazole has been researched along with Pregnancy in 113 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Oral fluconazole during the first trimester of pregnancy may be associated with unfavourable pregnancy outcomes."9.01The safety of oral fluconazole during the first trimester of pregnancy: a systematic review and meta-analysis. ( Jiang, CM; Jiang, HY; Zhang, X; Zhang, Z; Zhou, YY, 2019)
"The high prevalence of Candida infection, especially those due to non-albicans Candida species that are resistant to fluconazole, is a great concern in our setting and may lead to poor treatment outcomes."8.12Importance of Candida infection and fluconazole resistance in women with vaginal discharge syndrome in Namibia. ( Dunaiski, CM; Jung, H; Kock, MM; Peters, RPH, 2022)
"Within the Quebec Pregnancy Cohort (1998-2015), we identified women exposed to low- (≤ 150 mg) and high-dose (> 150 mg) fluconazole, and women who were not exposed."7.91Associations between low- and high-dose oral fluconazole and pregnancy outcomes: 3 nested case-control studies. ( Abrahamowicz, M; Bérard, A; Bernatsky, S; de Moura, CS; Gorgui, J; Sheehy, O; Zhao, JP, 2019)
"In this nationwide cohort study in Denmark, use of oral fluconazole in pregnancy was associated with a statistically significant increased risk of spontaneous abortion compared with risk among unexposed women and women with topical azole exposure in pregnancy."7.83Association Between Use of Oral Fluconazole During Pregnancy and Risk of Spontaneous Abortion and Stillbirth. ( Hviid, A; Melbye, M; Mølgaard-Nielsen, D; Pasternak, B; Svanström, H, 2016)
" She took a 150-mg dose of fluconazole 2 weeks ago for the treatment of vaginal candidiasis and she is worried about the effect on her child and pregnancy."7.81Fluconazole exposure during pregnancy. ( Bozzo, P; Kaplan, YC; Koren, G, 2015)
"Case reports suggest that long-term, high-dose fluconazole treatment for severe fungal infections during pregnancy causes a pattern of birth defects."7.79Use of oral fluconazole during pregnancy and the risk of birth defects. ( Hviid, A; Mølgaard-Nielsen, D; Pasternak, B, 2013)
"We evaluated pregnancy outcomes in 234 women exposed to fluconazole, 492 exposed to a topically administered azole preparation, 88 exposed to an oral azole preparation other than fluconazole, and 1629 not exposed to any of these agents during the first trimester of pregnancy Relative risks of having a baby with a congenital disorder for women exposed to fluconazole, oral azoles, and topical azoles in the first trimester of pregnancy compared with those who were unexposed were 1."7.70Pregnancy outcomes after maternal exposure to fluconazole. ( Jick, SS, 1999)
" We compared the pregnancy outcomes of 226 women exposed to fluconazole with that of 452 women exposed to nonteratogenic agents, with use of logistic regression to control for potential confounders."7.69Prospective assessment of pregnancy outcomes after first-trimester exposure to fluconazole. ( Botto, LD; Caramelli, L; Finardi, A; Fusco, D; Mastroiacovo, P; Mazzone, T; Serafini, MA, 1996)
"Recurrence is also more common in pregnant women, and therapeutic responses are reduced."5.38Yeast vaginitis during pregnancy: susceptibility testing of 13 antifungal drugs and boric acid and the detection of four virulence factors. ( Aydin, M; Güzel, AB; Ilkit, M; Kalkanci, A; Khalil, II; Kuştimur, S, 2012)
"A prescription-event monitoring (PEM) study has confirmed that fluconazole, a bis-triazole oral antifungal drug, is a safe and effective treatment for vaginal candidiasis."5.29Safety of fluconazole in the treatment of vaginal candidiasis. A prescription-event monitoring study, with special reference to the outcome of pregnancy. ( Inman, W; Pearce, G; Wilton, L, 1994)
" Fluconazole during pregnancy may be associated with spontaneous abortion and craniofacial and heart defects."5.22Vulvovaginal Candidiasis: A Review of the Evidence for the 2021 Centers for Disease Control and Prevention of Sexually Transmitted Infections Treatment Guidelines. ( Brookhart, C; Lazenby, G; Nyirjesy, P; Schwebke, J; Sobel, JD, 2022)
"The study showed no increased risk of congenital malformations, low birth weight or preterm birth in offspring to women who had used single dose fluconazole before conception or during pregnancy."5.09Risk of malformations and other outcomes in children exposed to fluconazole in utero. ( Czeizel, AE; Larsen, H; Nielsen, GL; Olesen, C; Olsen, J; Schønheyder, HC; Sorensen, HT; Steffensen, FH, 1999)
" Five were exposed to 200-800 mg fluconazole during pregnancy."5.05Cryptococcosis in pregnancy and the postpartum period: Case series and systematic review with recommendations for management. ( Boulware, DR; Evans, EE; Meya, DB; Muzoora, C; Nalintya, E; Ndyetukira, JF; Nuwagira, E; Pastick, KA; Rajasingham, R; Rhein, J; Skipper, C; Ssebambulidde, K; Stephens, N; Tugume, L, 2020)
" The oral antifungal agents used during pregnancy were fluconazole and itraconazole."5.05Fetal outcomes after maternal exposure to oral antifungal agents during pregnancy: A systematic review and meta-analysis. ( Liu, D; Wu, L; Zhang, C; Zhang, L, 2020)
"Oral fluconazole during the first trimester of pregnancy may be associated with unfavourable pregnancy outcomes."5.01The safety of oral fluconazole during the first trimester of pregnancy: a systematic review and meta-analysis. ( Jiang, CM; Jiang, HY; Zhang, X; Zhang, Z; Zhou, YY, 2019)
" Because half of all pregnancies are unplanned and pregnant women have an increased risk of VVC recurrence, the likelihood of inadvertently being exposed to fluconazole in pregnancy is increased."4.91Exposure to fluconazole and risk of congenital malformations in the offspring: A systematic review and meta-analysis. ( Alsaad, AM; Kaplan, YC; Koren, G, 2015)
"The high prevalence of Candida infection, especially those due to non-albicans Candida species that are resistant to fluconazole, is a great concern in our setting and may lead to poor treatment outcomes."4.12Importance of Candida infection and fluconazole resistance in women with vaginal discharge syndrome in Namibia. ( Dunaiski, CM; Jung, H; Kock, MM; Peters, RPH, 2022)
"Use of fluconazole and topical azoles was established by requiring one or more prescriptions during the first trimester of pregnancy."3.96Oral fluconazole use in the first trimester and risk of congenital malformations: population based cohort study. ( Bateman, BT; Gray, KJ; Hernandez-Diaz, S; Huybrechts, KF; Mogun, H; Straub, L; Zhu, Y, 2020)
"Within the Quebec Pregnancy Cohort (1998-2015), we identified women exposed to low- (≤ 150 mg) and high-dose (> 150 mg) fluconazole, and women who were not exposed."3.91Associations between low- and high-dose oral fluconazole and pregnancy outcomes: 3 nested case-control studies. ( Abrahamowicz, M; Bérard, A; Bernatsky, S; de Moura, CS; Gorgui, J; Sheehy, O; Zhao, JP, 2019)
" Information on fluconazole use in early pregnancy was collected by self-report from 31,645 mothers of birth defect cases and 11,612 mothers of unaffected controls."3.83Fluconazole use and birth defects in the National Birth Defects Prevention Study. ( Browne, ML; Carter, TC; Cunniff, CM; Druschel, CM; Howley, MM; Romitti, PA, 2016)
"In this nationwide cohort study in Denmark, use of oral fluconazole in pregnancy was associated with a statistically significant increased risk of spontaneous abortion compared with risk among unexposed women and women with topical azole exposure in pregnancy."3.83Association Between Use of Oral Fluconazole During Pregnancy and Risk of Spontaneous Abortion and Stillbirth. ( Hviid, A; Melbye, M; Mølgaard-Nielsen, D; Pasternak, B; Svanström, H, 2016)
" She took a 150-mg dose of fluconazole 2 weeks ago for the treatment of vaginal candidiasis and she is worried about the effect on her child and pregnancy."3.81Fluconazole exposure during pregnancy. ( Bozzo, P; Kaplan, YC; Koren, G, 2015)
"Case reports suggest that long-term, high-dose fluconazole treatment for severe fungal infections during pregnancy causes a pattern of birth defects."3.79Use of oral fluconazole during pregnancy and the risk of birth defects. ( Hviid, A; Mølgaard-Nielsen, D; Pasternak, B, 2013)
"We found no overall increased risk of congenital malformations after exposure to short-course treatment with fluconazole in early pregnancy."3.74Maternal use of fluconazole and risk of congenital malformations: a Danish population-based cohort study. ( Erichsen, R; Gislum, M; Nørgaard, M; Pedersen, L; Schønheyder, HC; Søgaard, KK; Sørensen, HT, 2008)
" We encountered a tuboovarian abscess caused by Candida glabrata after chemotherapy with an anticancer drug, methotrexate, in a febrile neutropenic patient."3.72Tuboovarian abscess caused by Candida glabrata in a febrile neutropenic patient. ( Mikamo, H; Ninomiya, M; Tamaya, T, 2003)
"We evaluated pregnancy outcomes in 234 women exposed to fluconazole, 492 exposed to a topically administered azole preparation, 88 exposed to an oral azole preparation other than fluconazole, and 1629 not exposed to any of these agents during the first trimester of pregnancy Relative risks of having a baby with a congenital disorder for women exposed to fluconazole, oral azoles, and topical azoles in the first trimester of pregnancy compared with those who were unexposed were 1."3.70Pregnancy outcomes after maternal exposure to fluconazole. ( Jick, SS, 1999)
" However, patients with this phenotype have been reported with a new dominant mutation at the FGFR2 locus as well as in the offspring of mothers taking the antifungal agent fluconazole during early pregnancy."3.70Evidence for digenic inheritance in some cases of Antley-Bixler syndrome? ( Adès, L; Baraitser, M; Das, D; DeLozier-Blanchet, C; Hindmarsh, P; Honour, JW; Kelly, T; Kumar, D; Malcolm, S; McKee, S; McKeehan, WL; Nelson, I; Reardon, W; Rumsby, G; Sillence, D; Smith, A; Winter, RM, 2000)
" We compared the pregnancy outcomes of 226 women exposed to fluconazole with that of 452 women exposed to nonteratogenic agents, with use of logistic regression to control for potential confounders."3.69Prospective assessment of pregnancy outcomes after first-trimester exposure to fluconazole. ( Botto, LD; Caramelli, L; Finardi, A; Fusco, D; Mastroiacovo, P; Mazzone, T; Serafini, MA, 1996)
" Other topics included an outline of the World Health Organization's (WHO) stepped-care strategy for pain management, a discussion on the benefits of fluconazole prophylaxis in treating opportunistic infections, and the need to confirm self-reported HIV infection to avoid the problem of some people attempting to gain a secondary benefit by claiming to be HIV-positive."3.69First women's HIV conference hears go-for-broke antiretroviral strategy. ( Mascolini, M, 1995)
" In December 2022, Ibrexafungerp received FDA approval for once monthly dosing to decrease the incidence of RVVC."3.01Ibrexafungerp for the Treatment of Vulvovaginal Candidiasis: Design, Development and Place in Therapy. ( Merjanian, L; Phillips, NA; Rocktashel, M, 2023)
"Fluconazole is a bis-triazole agent used in the treatment of superficial and systemic fungal infections, with vaginal candidiasis being one of the commonest indications to fluconazole treatment."2.72Maternal use of fluconazole and congenital malformations in the progeny: A meta-analysis of the literature. ( Budani, MC; Di Marzio, M; Fensore, S; Tiboni, GM, 2021)
"Fluconazole (FCZ) is an antifungal bis-triazole with potent inhibitory effect on the principal CYP-dependent metabolic pathway of PHT."2.69Teratological interaction between the bis-triazole antifungal agent fluconazole and the anticonvulsant drug phenytoin. ( Bellati, U; Di Ilio, C; Giampietro, F; Iammarrone, E; Lamonaca, D; Tiboni, GM, 1999)
"Fluconazole was replaced in both twins by liposomal amphotericin B and the incubators were changed."2.55Simultaneous primary invasive cutaneous aspergillosis in two preterm twins: case report and review of the literature. ( Astruc, D; Candolfi, E; Denis, J; Dillenseger, L; Gallais, F; Herbrecht, R; Koobar, O; Letscher-Bru, V; Sabou, M, 2017)
"The aim of this study was to build and verify a preliminary physiologically based pharmacokinetic (PBPK) model of Chinese pregnant women."1.56Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women. ( Li, X; Liu, D; Liu, X; Song, L; Xu, Y; Yu, Z; Zhou, T, 2020)
"If left untreated, vulvovaginal candidiasis (VVC) can lead to chorioamnionitis with subsequent abortion, prematurity and congenital infection of the neonate."1.56Prevalence of vulvovaginal candidiasis among pregnant women in the Ho municipality, Ghana: species identification and antifungal susceptibility of Candida isolates. ( Afeke, I; Agede, CY; Asiamah, EA; Deku, JG; Dodoo, C; Kasu, ES; Korbuvi, J; Kwawu, GS; Louis, B; Mbroh, HK; Mensah, P; Opintan, JA; Osei, GY; Tampuori, J; Waikhom, SD, 2020)
"Fluconazole (FLCZ) is an azole antifungal agent and it has shown excellent clinical activities in suppressing fungemia with Candida albicans after hematopoietic stem cell transplantation."1.48Breakthrough Candida guilliermondii (Meyerozyma guilliermondii) fungemia after cord blood transplantation for extranodal NK-cell lymphoma with azole prophylaxis. ( Ishida, F; Ito, T; Kikuchi, K; Nakazawa, H; Nishina, S; Sakai, H; Senoo, Y, 2018)
"Fluconazole treatment in utero decreased intestinal C."1.43Intra-amniotic Candida albicans infection induces mucosal injury and inflammation in the ovine fetal intestine. ( Hornef, MW; Jacobs, EM; Janssen, LE; Jobe, AH; Kallapur, SG; Kemp, MW; Kramer, BW; Newnham, JP; Nikiforou, M; Payne, MS; Saito, M; Wolfs, TG, 2016)
"Fluconazole treatment temporarily decreased the pulmonary and chorioamnion inflammatory responses."1.42Fluconazole treatment of intrauterine Candida albicans infection in fetal sheep. ( Jobe, AH; Kallapur, SG; Kemp, MW; Kramer, BW; Maneenil, G; Miura, Y; Newnham, JP; Payne, MS; Senthamarai Kannan, P, 2015)
"Intra-amniotic Candida infection is associated with preterm rupture of membranes, preterm labor, severe neonatal infection, and fetal death."1.39Intra-amniotic fluconazole therapy for Candida albicans intra-amniotic infection. ( Bean, LM; Beiswenger, TR; Dobak, WJ; Jackson, JR; Thorp, JA, 2013)
" Long-term administration of oral fluconazole was well accepted and effective at treating the multifocal C."1.39Multifocal Cryptococcus neoformans var. neoforms: infection, treatment, and monitoring by serial computed tomography in a Schmidt's red-tailed guenon (Cercopithecus ascanius schmidti). ( Adkesson, MJ; Colegrove, KM; Delaney, MA; Langan, JN; Muhlbauer, MC; Nevitt, BN; Rubin, DA, 2013)
"The patient with cryptococcal meningitis was treated with amphotericin B and fluconazole and the patient with cerebral aspergilloma with voriconazole."1.38Two rare cases of central nervous system opportunistic mycoses. ( Baršić, B; Mlinarić Missoni, E, 2012)
"Recurrence is also more common in pregnant women, and therapeutic responses are reduced."1.38Yeast vaginitis during pregnancy: susceptibility testing of 13 antifungal drugs and boric acid and the detection of four virulence factors. ( Aydin, M; Güzel, AB; Ilkit, M; Kalkanci, A; Khalil, II; Kuştimur, S, 2012)
"Fenticonazole was assessed by European Committee on Antimicrobial Susceptibility Testing and CLSI microdilution methods for the first time, and the results showed excellent agreement (97%) and significant interclass correlation coefficient (P < 0."1.35Fenticonazole activity measured by the methods of the European Committee on Antimicrobial Susceptibility Testing and CLSI against 260 Candida vulvovaginitis isolates from two European regions and annotations on the prevalent genotypes. ( Alexopoulos, EC; Antonopoulou, S; Aoun, M; Baka, S; Grigoriou, O; Kalambokas, T; Kouskouni, E; Logothetis, E; Papadias, K; Velegraki, A; Zannos, A, 2009)
"Co-administration of NVP and daily dosage of FLU (200 mg/day and 400 mg/day) results in markedly increased trough plasma NVP level when compared to the administration of NVP alone."1.34Plasma nevirapine levels, adverse events and efficacy of antiretroviral therapy among HIV-infected patients concurrently receiving nevirapine-based antiretroviral therapy and fluconazole. ( Athichathanabadi, C; Manosuthi, W; Phoorisri, T; Sungkanuparph, S; Uttayamakul, S, 2007)
" Dose-response relationship was investigated by treating animals with 0 (vehicle), 87."1.33Murine teratology of fluconazole: evaluation of developmental phase specificity and dose dependence. ( Giampietro, F; Tiboni, GM, 2005)
"The pregnancy was complicated by maternal human immunodeficiency virus (HIV) infection and multiple drug exposures, including fluconazole (400 mg/day) until the fifth month and then from 6 months to term, efavirenz, nevirapine, methadone, dapsone, pentamidine, and trimethoprim-sulfamethoxazole."1.33Prenatal exposure to fluconazole: an identifiable dysmorphic phenotype. ( Lopez-Rangel, E; Van Allen, MI, 2005)
"Fluconazole (FCZ) is a potent inhibitor of the cytochrome P450 (CYP)-mediated metabolism of the anti-epileptic agent phenytoin (PHT), a well-known human and animal teratogen."1.32Additional investigation on the potentiation of phenytoin teratogenicity by fluconazole. ( Angelucci, S; Bellati, U; Di Ilio, C; Giampietro, F; Moio, P; Tiboni, GM, 2003)
"A prescription-event monitoring (PEM) study has confirmed that fluconazole, a bis-triazole oral antifungal drug, is a safe and effective treatment for vaginal candidiasis."1.29Safety of fluconazole in the treatment of vaginal candidiasis. A prescription-event monitoring study, with special reference to the outcome of pregnancy. ( Inman, W; Pearce, G; Wilton, L, 1994)
"Fluconazole has been associated with various teratisms in animals, including craniofacial ossification defects, thin, wavy ribs, and renal pelvis defects."1.29Fluconazole-induced congenital anomalies in three infants. ( Abraham, J; Andersen, HF; Bartley, JA; Blomquist, IK; Pursley, TJ, 1996)

Research

Studies (113)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.88)18.7374
1990's18 (15.93)18.2507
2000's31 (27.43)29.6817
2010's44 (38.94)24.3611
2020's19 (16.81)2.80

Authors

AuthorsStudies
Antonopoulou, S1
Aoun, M1
Alexopoulos, EC1
Baka, S1
Logothetis, E1
Kalambokas, T1
Zannos, A1
Papadias, K1
Grigoriou, O1
Kouskouni, E1
Velegraki, A1
Nyirjesy, P1
Brookhart, C1
Lazenby, G1
Schwebke, J1
Sobel, JD1
Aleanizy, FS1
Taha, EI1
Salem-Bekhit, MM1
Felimban, AMJ1
Al-Suwayeh, SA1
Al-Joufi, FA1
Muharram, MM1
Alqahtani, FY1
Shakeel, F1
Youssof, AME1
Bayomi, M1
Abouelela, AEF1
de Souza, ANV1
Faria, MGI1
da Rocha, CE1
Philippsen, GS1
Silva, GCC1
da Silva, GR1
Inumaro, RS1
Gonçalves, JE1
Gazim, ZC1
Wietzikoski, S1
Lívero, FADR1
Seixas, FAV1
Wietzikoski Lovato, EC1
Dunaiski, CM1
Kock, MM1
Jung, H1
Peters, RPH1
Sucher, AJ1
Thai, A1
Tran, C1
Mantena, N1
Noronha, A1
Chahine, EB1
Bouglita, W1
Rabhi, S1
Raich, N1
Bouabid, C1
Belghith, C1
Slimani, O1
Hkimi, C1
Ghedira, K1
Karess, RE1
Guizani-Tabbane, L1
Attia, L1
Rabhi, I1
Metruccio, F3
Battistoni, M3
Di Renzo, F4
Moretto, A3
Menegola, E4
Carvalho, GC2
Marena, GD2
Leonardi, GR2
Sábio, RM2
Corrêa, I2
Chorilli, M2
Bauab, TM2
Pahwa, R1
Ahuja, M1
Phillips, NA1
Rocktashel, M1
Merjanian, L1
Zhang, Z1
Zhang, X1
Zhou, YY1
Jiang, CM1
Jiang, HY1
Toh, J1
Snowball, V1
Howley, MM2
Pastick, KA1
Nalintya, E1
Tugume, L1
Ssebambulidde, K1
Stephens, N1
Evans, EE1
Ndyetukira, JF1
Nuwagira, E1
Skipper, C1
Muzoora, C1
Meya, DB1
Rhein, J1
Boulware, DR1
Rajasingham, R1
Liu, D2
Zhang, C1
Wu, L1
Zhang, L2
Ghaddar, N1
Anastasiadis, E1
Halimeh, R1
Ghaddar, A1
Dhar, R1
AlFouzan, W1
Yusef, H1
El Chaar, M1
Waikhom, SD1
Afeke, I1
Kwawu, GS1
Mbroh, HK1
Osei, GY1
Louis, B1
Deku, JG1
Kasu, ES1
Mensah, P1
Agede, CY1
Dodoo, C1
Asiamah, EA1
Tampuori, J1
Korbuvi, J1
Opintan, JA1
Zhu, Y1
Bateman, BT1
Gray, KJ1
Hernandez-Diaz, S1
Mogun, H1
Straub, L1
Huybrechts, KF1
Song, L1
Yu, Z1
Xu, Y1
Li, X1
Liu, X1
Zhou, T1
Budani, MC1
Fensore, S1
Di Marzio, M1
Tiboni, GM5
Bender, RA1
Çalışkan, Ş1
Önal, B1
Aslancan, R1
Çalışkan, E1
Kusanovic, JP1
Romero, R1
Martinovic, C1
Silva, K1
Erez, O1
Maymon, E1
Díaz, F1
Ferrer, F1
Valdés, R1
Córdova, V1
Vargas, P1
Nilo, ME1
Le Cerf, P1
Mogensen, DM1
Pihl, MB1
Skakkebæk, NE1
Andersen, HR1
Juul, A1
Kyhl, HB1
Swan, S1
Kristensen, DM1
Andersen, MS1
Lind, DV1
Jensen, TK1
Gallais, F1
Denis, J1
Koobar, O1
Dillenseger, L1
Astruc, D1
Herbrecht, R1
Candolfi, E1
Letscher-Bru, V1
Sabou, M1
Nakazawa, H1
Nishina, S1
Senoo, Y1
Sakai, H1
Ito, T1
Kikuchi, K1
Ishida, F1
Pasternak, B4
Wintzell, V1
Furu, K1
Engeland, A1
Neovius, M1
Stephansson, O1
Brandão, LDS1
Boniek, D1
Resende Stoianoff, MA1
da Mata, FMR1
de Azevedo, PRM1
Fernandes, JV1
Andrade, VS1
Paquette, VC1
Elwood, C1
Bérard, A1
Sheehy, O1
Zhao, JP1
Gorgui, J1
Bernatsky, S1
de Moura, CS1
Abrahamowicz, M1
Kroeker, R1
Chichester, L1
Lee, GH1
Worlien, JM1
Hernández-Torres, A1
García-Vázquez, E1
Laso-Ortiz, A1
Herrero-Martínez, JA1
Gómez-Gómez, J1
Mølgaard-Nielsen, D3
Hviid, A3
Ssali, A1
Namukwaya, S1
Bufumbo, L1
Seeley, J1
G Lalloo, D1
Kamali, A1
Parkes-Ratanshi, R1
Nevitt, BN1
Langan, JN1
Adkesson, MJ1
Delaney, MA1
Rubin, DA1
Muhlbauer, MC1
Colegrove, KM1
Vlachadis, N1
Iliodromiti, Z1
Vrachnis, N1
Magee, LA1
Margo, K1
Waldman, L1
Reddy, SB1
Kassim, A1
Dettloff, J1
Reddy, VB1
Pilmis, B1
Jullien, V1
Sobel, J1
Lecuit, M1
Lortholary, O1
Charlier, C1
Baptista, MI1
Nona, J1
Ferreira, M1
Sampaio, I1
Abrantes, M1
Tomé, MT1
Neto, MT1
Barroso, R1
Serelha, M1
Virella, D1
Alsaad, AM1
Kaplan, YC2
Koren, G2
Maneenil, G1
Payne, MS2
Senthamarai Kannan, P1
Kallapur, SG2
Kramer, BW2
Newnham, JP2
Miura, Y1
Jobe, AH2
Kemp, MW2
Bozzo, P1
Carter, TC1
Browne, ML1
Romitti, PA1
Cunniff, CM1
Druschel, CM1
Wise, J1
Svanström, H1
Melbye, M1
Yang, L1
Su, MQ1
Ma, YY1
Xin, YJ1
Han, RB1
Zhang, R1
Wen, J1
Hao, XK1
Briglio, J1
Nikiforou, M1
Jacobs, EM1
Hornef, MW1
Saito, M1
Janssen, LE1
Wolfs, TG1
Aschenbrenner, DS1
Cassina, M1
Cagnoli, GA1
Zuccarello, D1
Di Gianantonio, E1
Clementi, M1
Barzin, A1
Mounsey, A1
Tapia, CV1
Hermosilla, G1
Fortes, P1
Alburquenque, C1
Bucarey, S1
Salinas, H1
Rodas, PI1
Díaz, MC1
Magne, F1
Fucic, A1
Markovic, D1
Herceg, Z1
Gamulin, M1
Katic, J1
Stojkovic, R1
Ferencic, Z1
Mildner, B1
Jazbec, AM1
Dobranic, T1
Nakamura, S1
Izumikawa, K1
Seki, M1
Kakeya, H1
Yamamoto, Y1
Yanagihara, K1
Miyazaki, Y1
Kohno, S1
Carey, JC1
Martinez, L1
Balken, E1
Leen-Mitchell, M1
Robertson, J1
Pikuza, VV1
Chilova, RA1
Ishchenko, AI1
Marotta, F1
Carletti, E1
Mudumbi, SV1
Marinov, B3
Schwentner, L1
Wulff, C1
Kreienberg, R1
Herr, D1
Kalkanci, A1
Güzel, AB1
Khalil, II1
Aydin, M1
Ilkit, M1
Kuştimur, S1
Lachhab, L1
Rasmouni, K1
Ait Ben Haddou, EH1
Maamar, M1
Seffar, M1
Regragui, W1
Benomar, A1
Yahyaoui, M1
Gomez-Moyano, E1
Cid Lama, A1
Fernández Ballesteros, MD1
Lova Navarro, M1
Vera Casaño, A1
Crespo Erchiga, V1
Mlinarić Missoni, E1
Baršić, B1
Bean, LM1
Jackson, JR1
Dobak, WJ1
Beiswenger, TR1
Thorp, JA1
Bauters, TG1
Dhont, MA1
Temmerman, MI1
Nelis, HJ1
Broccia, ML1
Giavini, E1
Stenberg-Nilsen, H1
Petkova, C1
Kolarov, G2
Georgiev, S1
Iunakova, M1
VAHLENKAMP, H1
Mikamo, H1
Ninomiya, M1
Tamaya, T1
Giampietro, F3
Angelucci, S1
Moio, P1
Bellati, U2
Di Ilio, C2
Petkova, S1
Konovalova, M1
Laffitte, E1
Genton, B1
Panizzon, RG1
Hsieh, WB1
Leung, C1
Lopez-Rangel, E1
Van Allen, MI1
Fellows, P1
Rodrigo, N1
Perera, KN1
Ranwala, R1
Jayasinghe, S1
Warnakulasuriya, A1
Hapuarachchi, S1
Crawford, JT1
Pereira, L1
Buckmaster, J1
Gravett, MG1
Tolosa, JE1
Manosuthi, W1
Athichathanabadi, C1
Uttayamakul, S1
Phoorisri, T1
Sungkanuparph, S1
Annapureddy, SR1
Masterson, SW1
David, HG1
Greig, JR1
Benjamin, DK1
Nørgaard, M1
Pedersen, L1
Gislum, M1
Erichsen, R1
Søgaard, KK1
Schønheyder, HC2
Sørensen, HT1
Krcmery, S1
Masar, O2
Krcmery, V2
Inman, W1
Pearce, G1
Wilton, L1
Pursley, TJ1
Blomquist, IK1
Abraham, J1
Andersen, HF1
Bartley, JA1
Huttova, M1
Mastroiacovo, P1
Mazzone, T1
Botto, LD1
Serafini, MA1
Finardi, A1
Caramelli, L1
Fusco, D1
Campomori, A1
Bonati, M1
Wray, CM1
Baud, O1
Boithias, C1
Lacaze-Masmonteil, T1
Ville, Y1
Guibert, M1
Zupan, V1
Chabernaud, JL1
André, P1
Nordmann, P1
Frydman, R1
Dehan, M1
Aleck, KA1
Bartley, DL1
Sanchez, JM1
Moya, G1
Albukrek, D1
Davidson, S1
Merlob, P1
Jick, SS1
Iammarrone, E1
Lamonaca, D1
Sorensen, HT1
Nielsen, GL1
Olesen, C1
Larsen, H1
Steffensen, FH1
Olsen, J1
Czeizel, AE1
Reardon, W1
Smith, A1
Honour, JW1
Hindmarsh, P1
Das, D1
Rumsby, G1
Nelson, I1
Malcolm, S1
Adès, L1
Sillence, D1
Kumar, D1
DeLozier-Blanchet, C1
McKee, S1
Kelly, T1
McKeehan, WL1
Baraitser, M1
Winter, RM1
Baleta, A1
Busowski, JD1
Safdar, A1
Mascolini, M1
Paz, A1
Gonen, R1
Potasman, I1
Sikić, J1
Vukojević, N1
Katusić, D1
Sarić, B1
Laufer, B1
Bender, HG1
Lee, BE1
Feinberg, M1
Abraham, JJ1
Murthy, AR1
Arilla, MC1
Carbonero, JL1
Schneider, J1
Regúlez, P1
Quindós, G1
Pontón, J1
Cisterna, R1

Reviews

15 reviews available for fluconazole and Pregnancy

ArticleYear
Vulvovaginal Candidiasis: A Review of the Evidence for the 2021 Centers for Disease Control and Prevention of Sexually Transmitted Infections Treatment Guidelines.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 04-13, Volume: 74, Issue:Suppl_2

    Topics: Antifungal Agents; Candida albicans; Candidiasis, Vulvovaginal; Centers for Disease Control and Prev

2022
Ibrexafungerp for the Treatment of Vulvovaginal Candidiasis: Design, Development and Place in Therapy.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Antifungal Agents; Azoles; Candida albicans; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans;

2023
The safety of oral fluconazole during the first trimester of pregnancy: a systematic review and meta-analysis.
    BJOG : an international journal of obstetrics and gynaecology, 2019, Volume: 126, Issue:13

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Antifungal Agents; Candidiasis, Vulvovaginal; Cra

2019
Cryptococcosis in pregnancy and the postpartum period: Case series and systematic review with recommendations for management.
    Medical mycology, 2020, Apr-01, Volume: 58, Issue:3

    Topics: Adolescent; Adult; Amphotericin B; Antifungal Agents; Clinical Trials as Topic; Cryptococcus neoform

2020
Fetal outcomes after maternal exposure to oral antifungal agents during pregnancy: A systematic review and meta-analysis.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2020, Volume: 148, Issue:1

    Topics: Abortion, Spontaneous; Antifungal Agents; Case-Control Studies; Cohort Studies; Congenital Abnormali

2020
Maternal use of fluconazole and congenital malformations in the progeny: A meta-analysis of the literature.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 100

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Antifungal Agents; Candidiasis, Vulvovaginal; Do

2021
Simultaneous primary invasive cutaneous aspergillosis in two preterm twins: case report and review of the literature.
    BMC infectious diseases, 2017, 08-02, Volume: 17, Issue:1

    Topics: Adult; Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Diseases in Twins; F

2017
[Candida sp endocarditis. Experience in a third-level hospital and review of the literature].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2013, Volume: 26, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacteria

2013
Antifungal drugs during pregnancy: an updated review.
    The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:1

    Topics: Administration, Intravenous; Administration, Topical; Amphotericin B; Anti-Infective Agents, Local;

2015
Exposure to fluconazole and risk of congenital malformations in the offspring: A systematic review and meta-analysis.
    Reproductive toxicology (Elmsford, N.Y.), 2015, Volume: 52

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Candidiasis, Vulvovaginal; Craniofacial Abnormalitie

2015
Pulmonary cryptococcosis in late pregnancy and review of published literature.
    Mycopathologia, 2009, Volume: 167, Issue:3

    Topics: Adult; Antifungal Agents; Cryptococcosis; Diagnosis, Differential; Female; Fluconazole; Humans; Lung

2009
Determination of human teratogenicity by the astute clinician method: review of illustrative agents and a proposal of guidelines.
    Birth defects research. Part A, Clinical and molecular teratology, 2009, Volume: 85, Issue:1

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Antirheumatic Agents; Congenital Abnormalities; Evid

2009
Exacerbation of a maternal hiatus hernia in early pregnancy presenting with symptoms of hyperemesis gravidarum: case report and review of the literature.
    Archives of gynecology and obstetrics, 2011, Volume: 283, Issue:3

    Topics: Adult; Antifungal Agents; Candidiasis; Cesarean Section; Female; Fluconazole; Hernia, Hiatal; Humans

2011
[Fluconazole administration during pregnancy].
    Harefuah, 1998, Volume: 135, Issue:5-6

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Candidiasis; Candidiasis, Vulvovaginal; Female; Fluc

1998
[Current developments in antimycotic therapy in gynecology and obstetrics].
    Der Gynakologe, 1992, Volume: 25, Issue:4

    Topics: Animals; Antifungal Agents; Candidiasis, Vulvovaginal; Dose-Response Relationship, Drug; Female; Flu

1992

Trials

5 trials available for fluconazole and Pregnancy

ArticleYear
Pregnancy in HIV clinical trials in Sub Saharan Africa: failure of consent or contraception?
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Adult; Africa South of the Sahara; Antifungal Agents; Condoms; Condoms, Female; Contraception; Contr

2013
[Comparison of clinical efficacy and safety of domestic generic and original fluconazoles in the treatment of pregnant women with vulvovaginal candidiasis].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2008, Volume: 53, Issue:7-8

    Topics: Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Drugs, Generic; Female; Fluconazole; Humans; Pr

2008
[Some opportunities for the application of the drug mycosyst (preliminary communication)].
    Akusherstvo i ginekologiia, 2003, Volume: 42 Suppl 1

    Topics: Adult; Antifungal Agents; Clinical Trials as Topic; Female; Fluconazole; Humans; Middle Aged; Pregna

2003
Teratological interaction between the bis-triazole antifungal agent fluconazole and the anticonvulsant drug phenytoin.
    Teratology, 1999, Volume: 59, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Antifungal Agents; Body Weight; Cleft Palate;

1999
Risk of malformations and other outcomes in children exposed to fluconazole in utero.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:2

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antifungal Agents; Denmark; Female; Fluconazole; Fol

1999

Other Studies

93 other studies available for fluconazole and Pregnancy

ArticleYear
Fenticonazole activity measured by the methods of the European Committee on Antimicrobial Susceptibility Testing and CLSI against 260 Candida vulvovaginitis isolates from two European regions and annotations on the prevalent genotypes.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Adult; Antifungal Agents; Candida albicans; Candida glabrata; Candidiasis, Vulvovaginal; Cluster Ana

2009
Formulation and
    Drug development and industrial pharmacy, 2021, Volume: 47, Issue:12

    Topics: Antifungal Agents; Delivery, Obstetric; Excipients; Female; Fluconazole; Gels; Humans; Nanogels; Pol

2021
Bioactive compounds with antifungal activity against pathogens isolated from pregnant woman: Gallesia integrifolia (garlic wood) is a promising treatment for vulvovaginal candidiasis.
    Journal of ethnopharmacology, 2022, Sep-15, Volume: 295

    Topics: Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candida tropicalis; Candidiasis, Vul

2022
Importance of Candida infection and fluconazole resistance in women with vaginal discharge syndrome in Namibia.
    Antimicrobial resistance and infection control, 2022, 08-15, Volume: 11, Issue:1

    Topics: Antifungal Agents; Candida; Candidiasis; Cross-Sectional Studies; Female; Fluconazole; Humans; Male;

2022
Ibrexafungerp: A new triterpenoid antifungal.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2022, 12-05, Volume: 79, Issue:24

    Topics: Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Child; Echinocandins; Female; Fluconazole; Huma

2022
Microbiological and molecular screening of
    Journal of medical microbiology, 2022, Volume: 71, Issue:9

    Topics: Antifungal Agents; Candida; Candida albicans; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans

2022
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture.
    Archives of toxicology, 2023, Volume: 97, Issue:2

    Topics: Alcohol Drinking; Animals; Anticonvulsants; Antifungal Agents; Ethanol; Female; Fluconazole; Humans;

2023
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture.
    Archives of toxicology, 2023, Volume: 97, Issue:2

    Topics: Alcohol Drinking; Animals; Anticonvulsants; Antifungal Agents; Ethanol; Female; Fluconazole; Humans;

2023
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture.
    Archives of toxicology, 2023, Volume: 97, Issue:2

    Topics: Alcohol Drinking; Animals; Anticonvulsants; Antifungal Agents; Ethanol; Female; Fluconazole; Humans;

2023
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture.
    Archives of toxicology, 2023, Volume: 97, Issue:2

    Topics: Alcohol Drinking; Animals; Anticonvulsants; Antifungal Agents; Ethanol; Female; Fluconazole; Humans;

2023
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture.
    Archives of toxicology, 2023, Volume: 97, Issue:2

    Topics: Alcohol Drinking; Animals; Anticonvulsants; Antifungal Agents; Ethanol; Female; Fluconazole; Humans;

2023
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture.
    Archives of toxicology, 2023, Volume: 97, Issue:2

    Topics: Alcohol Drinking; Animals; Anticonvulsants; Antifungal Agents; Ethanol; Female; Fluconazole; Humans;

2023
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture.
    Archives of toxicology, 2023, Volume: 97, Issue:2

    Topics: Alcohol Drinking; Animals; Anticonvulsants; Antifungal Agents; Ethanol; Female; Fluconazole; Humans;

2023
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture.
    Archives of toxicology, 2023, Volume: 97, Issue:2

    Topics: Alcohol Drinking; Animals; Anticonvulsants; Antifungal Agents; Ethanol; Female; Fluconazole; Humans;

2023
Moderate alcohol consumption during pregnancy increases potency of two different drugs (the antifungal fluconazole and the antiepileptic valproate) in inducing craniofacial defects: prediction by the in vitro rat whole embryo culture.
    Archives of toxicology, 2023, Volume: 97, Issue:2

    Topics: Alcohol Drinking; Animals; Anticonvulsants; Antifungal Agents; Ethanol; Female; Fluconazole; Humans;

2023
Lycopene, Mesoporous Silica Nanoparticles and Their Association: A Possible Alternative against Vulvovaginal Candidiasis?
    Molecules (Basel, Switzerland), 2022, Dec-05, Volume: 27, Issue:23

    Topics: Aged; Antifungal Agents; Candida; Candida albicans; Candidiasis, Vulvovaginal; Female; Fluconazole;

2022
Lycopene, Mesoporous Silica Nanoparticles and Their Association: A Possible Alternative against Vulvovaginal Candidiasis?
    Molecules (Basel, Switzerland), 2022, Dec-05, Volume: 27, Issue:23

    Topics: Aged; Antifungal Agents; Candida; Candida albicans; Candidiasis, Vulvovaginal; Female; Fluconazole;

2022
Lycopene, Mesoporous Silica Nanoparticles and Their Association: A Possible Alternative against Vulvovaginal Candidiasis?
    Molecules (Basel, Switzerland), 2022, Dec-05, Volume: 27, Issue:23

    Topics: Aged; Antifungal Agents; Candida; Candida albicans; Candidiasis, Vulvovaginal; Female; Fluconazole;

2022
Lycopene, Mesoporous Silica Nanoparticles and Their Association: A Possible Alternative against Vulvovaginal Candidiasis?
    Molecules (Basel, Switzerland), 2022, Dec-05, Volume: 27, Issue:23

    Topics: Aged; Antifungal Agents; Candida; Candida albicans; Candidiasis, Vulvovaginal; Female; Fluconazole;

2022
Nanocellulose-gellan cross-linked scaffolds for vaginal delivery of fluconazole.
    International journal of biological macromolecules, 2023, Feb-28, Volume: 229

    Topics: Delivery, Obstetric; Drug Delivery Systems; Female; Fluconazole; Humans; Polymers; Polysaccharides,

2023
Postpartum sepsis caused by an intra-abdominal yeast infection.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2020, Volume: 40, Issue:3

    Topics: Adult; Antifungal Agents; Candida albicans; Candidiasis; Female; Fluconazole; Humans; Postpartum Per

2020
Using meta-analyses to improve risk estimates of specific birth defects.
    BJOG : an international journal of obstetrics and gynaecology, 2019, Volume: 126, Issue:13

    Topics: Female; Fluconazole; Humans; Pregnancy; Pregnancy Trimester, First; Risk Factors

2019
Prevalence and antifungal susceptibility of Candida albicans causing vaginal discharge among pregnant women in Lebanon.
    BMC infectious diseases, 2020, Jan-13, Volume: 20, Issue:1

    Topics: Adult; Amphotericin B; Antifungal Agents; Candida albicans; Candida glabrata; Candidiasis, Vulvovagi

2020
Prevalence of vulvovaginal candidiasis among pregnant women in the Ho municipality, Ghana: species identification and antifungal susceptibility of Candida isolates.
    BMC pregnancy and childbirth, 2020, May-06, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candida parapsilo

2020
Oral fluconazole use in the first trimester and risk of congenital malformations: population based cohort study.
    BMJ (Clinical research ed.), 2020, May-20, Volume: 369

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Adult; Antifungal Agents; Candidiasis, Vulvovagin

2020
Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women.
    Biopharmaceutics & drug disposition, 2020, Volume: 41, Issue:6

    Topics: Adult; Asian People; Aztreonam; Biological Transport; Ceftazidime; Ceftriaxone; Cefuroxime; Female;

2020
Treatment methods for vulvovaginal candidiasis in pregnancy.
    Journal de mycologie medicale, 2021, Volume: 31, Issue:3

    Topics: Antifungal Agents; Candida albicans; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Pregnan

2021
Transabdominal collection of amniotic fluid "sludge" and identification of Candida albicans intra-amniotic infection.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2018, Volume: 31, Issue:10

    Topics: Adult; Amniocentesis; Amniotic Fluid; Antifungal Agents; Candida albicans; Candidiasis; Cervix Uteri

2018
Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study.
    Environmental health : a global access science source, 2017, 06-21, Volume: 16, Issue:1

    Topics: Adult; Androgen Antagonists; Antifungal Agents; Denmark; Female; Fluconazole; Genitalia, Male; Human

2017
Breakthrough Candida guilliermondii (Meyerozyma guilliermondii) fungemia after cord blood transplantation for extranodal NK-cell lymphoma with azole prophylaxis.
    Transplant infectious disease : an official journal of the Transplantation Society, 2018, Volume: 20, Issue:4

    Topics: Adult; Antibiotic Prophylaxis; Antifungal Agents; Candida; Candidemia; Candidiasis, Invasive; Cord B

2018
Oral Fluconazole in Pregnancy and Risk of Stillbirth and Neonatal Death.
    JAMA, 2018, 06-12, Volume: 319, Issue:22

    Topics: Administration, Oral; Antifungal Agents; Cohort Studies; Female; Fluconazole; Humans; Infant, Newbor

2018
Prevalence and antifungal susceptibility of Candida species among pregnant women attending a school maternity at Natal, Brazil.
    Letters in applied microbiology, 2018, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Amphotericin B; Antifungal Agents; Brazil; Candida; Candida glabrata; Candidiasis

2018
The safety of oral fluconazole therapy in pregnancy.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2019, 02-19, Volume: 191, Issue:7

    Topics: Antifungal Agents; Case-Control Studies; Female; Fluconazole; Pregnancy

2019
Associations between low- and high-dose oral fluconazole and pregnancy outcomes: 3 nested case-control studies.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2019, 02-19, Volume: 191, Issue:7

    Topics: Abortion, Spontaneous; Administration, Oral; Adolescent; Adult; Antifungal Agents; Candidiasis, Vulv

2019
Effects of Pregnancy, Outdoor Access, and Antifungal Medication on Hair Loss in Breeding-age Female Pigtailed Macaques (
    Comparative medicine, 2019, 05-01, Volume: 69, Issue:3

    Topics: Age Factors; Alopecia; Animals; Antifungal Agents; Breeding; Coccidioidomycosis; Female; Fluconazole

2019
Use of oral fluconazole during pregnancy and the risk of birth defects.
    The New England journal of medicine, 2013, Aug-29, Volume: 369, Issue:9

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Adult; Antifungal Agents; Cohort Studies; Denmark

2013
Multifocal Cryptococcus neoformans var. neoforms: infection, treatment, and monitoring by serial computed tomography in a Schmidt's red-tailed guenon (Cercopithecus ascanius schmidti).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2013, Volume: 44, Issue:3

    Topics: Animals; Antifungal Agents; Cercopithecus; Cryptococcosis; Cryptococcus neoformans; Female; Fluconaz

2013
Oral fluconazole during pregnancy and risk of birth defects.
    The New England journal of medicine, 2013, 11-21, Volume: 369, Issue:21

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Female; Fluconazole; Humans; Pregnancy

2013
Oral fluconazole during pregnancy and risk of birth defects.
    The New England journal of medicine, 2013, 11-21, Volume: 369, Issue:21

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Female; Fluconazole; Humans; Pregnancy

2013
ACP Journal Club. Fluconazole use during the first trimester of pregnancy was not associated with most major birth defects.
    Annals of internal medicine, 2014, Jan-21, Volume: 160, Issue:2

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Female; Fluconazole; Humans; Pregnancy

2014
Review: some clinical tests performed by specialists identify rotator cuff disease or tears.
    Annals of internal medicine, 2014, Mar-18, Volume: 160, Issue:6

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Female; Fluconazole; Humans; Pregnancy

2014
Neutrophilic Fixed Drug Eruption.
    The American Journal of dermatopathology, 2015, Volume: 37, Issue:7

    Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Drug Erupt

2015
Invasive fungal infection in neonatal intensive care units: a multicenter survey.
    Journal of chemotherapy (Florence, Italy), 2016, Volume: 28, Issue:1

    Topics: Amphotericin B; Antifungal Agents; Cross Infection; Drug Resistance, Fungal; Female; Fluconazole; Ge

2016
Fluconazole treatment of intrauterine Candida albicans infection in fetal sheep.
    Pediatric research, 2015, Volume: 77, Issue:6

    Topics: Analysis of Variance; Animals; Antifungal Agents; Candidiasis; Female; Fetal Diseases; Fluconazole;

2015
Fluconazole exposure during pregnancy.
    Canadian family physician Medecin de famille canadien, 2015, Volume: 61, Issue:8

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Huma

2015
Fluconazole use and birth defects in the National Birth Defects Prevention Study.
    American journal of obstetrics and gynecology, 2016, Volume: 214, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Antifungal Agents; Candidiasis; Case-Control Studies; Female; Fl

2016
Oral antifungal is associated with increased risk of miscarriage.
    BMJ (Clinical research ed.), 2016, Jan-06, Volume: 352

    Topics: Abortion, Spontaneous; Antifungal Agents; Female; Fluconazole; Humans; Pregnancy; Stillbirth

2016
Association Between Use of Oral Fluconazole During Pregnancy and Risk of Spontaneous Abortion and Stillbirth.
    JAMA, 2016, Jan-05, Volume: 315, Issue:1

    Topics: Abortion, Spontaneous; Administration, Oral; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Ca

2016
Epidemiology, species distribution, antifungal susceptibility, and ERG11 mutations of Candida species isolated from pregnant Chinese Han women.
    Genetics and molecular research : GMR, 2016, Apr-28, Volume: 15, Issue:2

    Topics: Adult; Antifungal Agents; Candida; Candidiasis; Cytochrome P-450 Enzyme System; Drug Resistance, Fun

2016
Oral fluconazole is often used during pregnancy in the treatment of vulvovaginal candidiasis despite safety concerns to the fetus.
    Evidence-based nursing, 2016, Volume: 19, Issue:4

    Topics: Administration, Oral; Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fetus; Fluconazole; Huma

2016
Intra-amniotic Candida albicans infection induces mucosal injury and inflammation in the ovine fetal intestine.
    Scientific reports, 2016, 07-14, Volume: 6

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Chorioamnionitis; Cytokines; Female; Fetu

2016
The FDA Reevaluates Oral Fluconazole Use in Pregnancy.
    The American journal of nursing, 2016, Volume: 116, Issue:8

    Topics: Abortion, Spontaneous; Administration, Oral; Antifungal Agents; Female; Fluconazole; Humans; Pregnan

2016
Human teratogens and genetic phenocopies. Understanding pathogenesis through human genes mutation.
    European journal of medical genetics, 2017, Volume: 60, Issue:1

    Topics: Abnormalities, Drug-Induced; Angiotensin-Converting Enzyme Inhibitors; Animals; Female; Fetal Diseas

2017
PURLs: Yeast infection in pregnancy? Think twice about fluconazole.
    The Journal of family practice, 2016, Volume: 65, Issue:9

    Topics: Abortion, Spontaneous; Administration, Oral; Administration, Topical; Antifungal Agents; Azoles; Fem

2016
Genotyping and Persistence of Candida albicans from Pregnant Women with Vulvovaginal Candidiasis.
    Mycopathologia, 2017, Volume: 182, Issue:3-4

    Topics: Administration, Topical; Adolescent; Adult; Antifungal Agents; Candida albicans; Candidiasis, Vulvov

2017
Developmental and transplacental genotoxicology: fluconazole.
    Mutation research, 2008, Nov-17, Volume: 657, Issue:1

    Topics: Aging; Animals; Female; Fluconazole; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Micronucleu

2008
Fluconazole alters CYP26 gene expression in mouse embryos.
    Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 27, Issue:2

    Topics: Administration, Oral; Animals; Antifungal Agents; Cytochrome P-450 Enzyme System; Cytochrome P450 Fa

2009
Disseminated cryptococcosis in an HIV-negative pregnancy: a case of cryptococcal septic abortion complicating an immunocompetent pregnancy.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2010, Volume: 14, Issue:4

    Topics: Abortion, Septic; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Female; Fluconazole; H

2010
[Application of Pfizer drugs in the obstetrics and gynecology practice].
    Akusherstvo i ginekologiia, 2009, Volume: 48 Suppl 1

    Topics: Anti-Bacterial Agents; Antifungal Agents; Cabergoline; Carboprost; Clindamycin; Dopamine Agonists; D

2009
Yeast vaginitis during pregnancy: susceptibility testing of 13 antifungal drugs and boric acid and the detection of four virulence factors.
    Medical mycology, 2012, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Amphotericin B; Animals; Antifungal Agents; Boric Acids; Candida albicans; Candid

2012
Fluconazole: teratogenicity.
    Prescrire international, 2012, Volume: 21, Issue:125

    Topics: Adult; Antifungal Agents; Female; Fluconazole; Humans; Pregnancy; Pregnancy Complications, Infectiou

2012
Cryptococcosis in an immunocompetent pregnant woman.
    Revue neurologique, 2013, Volume: 169, Issue:1

    Topics: Adult; Amphotericin B; Antifungal Agents; Apgar Score; Brain; Cryptococcosis; Female; Fluconazole; H

2013
[The Polish Gynecological Society Expert Committee recomendations regarding application of fluconazole in the treatment of vulvovaginal candidiasis].
    Ginekologia polska, 2012, Volume: 83, Issue:6

    Topics: Acute Disease; Administration, Topical; Antifungal Agents; Candida; Candidiasis, Vulvovaginal; Chron

2012
[Efficacy of voriconazole treatment in chronic vulvovaginal candidosis due to Candida glabrata].
    Revista iberoamericana de micologia, 2013, Jan-03, Volume: 30, Issue:1

    Topics: Adult; Antifungal Agents; Candida glabrata; Candidiasis, Vulvovaginal; Cesarean Section; Drug Evalua

2013
Two rare cases of central nervous system opportunistic mycoses.
    Arhiv za higijenu rada i toksikologiju, 2012, Volume: 63, Issue:4

    Topics: Adult; Amphotericin B; Antifungal Agents; Aspergillus nidulans; Cryptococcus neoformans; Female; Flu

2012
Intra-amniotic fluconazole therapy for Candida albicans intra-amniotic infection.
    Obstetrics and gynecology, 2013, Volume: 121, Issue:2 Pt 2 Sup

    Topics: Abruptio Placentae; Adult; Amnion; Anti-Bacterial Agents; Antifungal Agents; Candidiasis; Cesarean S

2013
Prevalence of vulvovaginal candidiasis and susceptibility to fluconazole in women.
    American journal of obstetrics and gynecology, 2002, Volume: 187, Issue:3

    Topics: Adult; Aged; Antifungal Agents; Candida; Candidiasis, Vulvovaginal; Contraceptives, Oral; Estrogen R

2002
Pathogenic pathways in fluconazole-induced branchial arch malformations.
    Birth defects research. Part A, Clinical and molecular teratology, 2003, Volume: 67, Issue:2

    Topics: Animals; Antifungal Agents; Apoptosis; Branchial Region; Cell Division; Cell Movement; Embryonic and

2003
[Use of fluconazole during pregnancy].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2003, May-01, Volume: 123, Issue:9

    Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Dose-Response Relationship, Drug; Female; Fluconazole;

2003
[On the subject of annular placenta. Report on a complete human zonal placenta with velamentous insertion of the umbilical cord].
    Geburtshilfe und Frauenheilkunde, 1961, Volume: 21

    Topics: Female; Fluconazole; Humans; Placenta; Placenta Diseases; Pregnancy; Umbilical Cord

1961
Tuboovarian abscess caused by Candida glabrata in a febrile neutropenic patient.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2003, Volume: 9, Issue:3

    Topics: Abscess; Adult; Amphotericin B; Antifungal Agents; Antimetabolites, Antineoplastic; Candida glabrata

2003
Additional investigation on the potentiation of phenytoin teratogenicity by fluconazole.
    Toxicology letters, 2003, Dec-10, Volume: 145, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Cleft Palate; Dose-Response Relationship, Drug; Drug

2003
[Three years experience of using mycosyst].
    Akusherstvo i ginekologiia, 2004, Volume: 43 Suppl 2

    Topics: Abortion, Therapeutic; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Hum

2004
Cutaneous leishmaniasis caused by Leishmania tropica: treatment with oral fluconazole.
    Dermatology (Basel, Switzerland), 2005, Volume: 210, Issue:3

    Topics: Administration, Oral; Adult; Animals; Antifungal Agents; Diagnosis, Differential; Female; Fluconazol

2005
Candidal arthritis after complete treatment of systemic candidiasis.
    Journal of the Chinese Medical Association : JCMA, 2005, Volume: 68, Issue:4

    Topics: Amphotericin B; Antifungal Agents; Arthritis; Candidiasis; Diabetes, Gestational; Female; Fluconazol

2005
Murine teratology of fluconazole: evaluation of developmental phase specificity and dose dependence.
    Pediatric research, 2005, Volume: 58, Issue:1

    Topics: Abnormalities, Drug-Induced; Alcian Blue; Animals; Anthraquinones; Antifungal Agents; Body Weight; C

2005
Prenatal exposure to fluconazole: an identifiable dysmorphic phenotype.
    Birth defects research. Part A, Clinical and molecular teratology, 2005, Volume: 73, Issue:11

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Antifungal Agents; Female; Fluconazole; HIV In

2005
Medication in the wrong hands?
    Community practitioner : the journal of the Community Practitioners' & Health Visitors' Association, 2005, Volume: 78, Issue:12

    Topics: Antifungal Agents; Contraindications; Drug and Narcotic Control; Female; Fluconazole; Humans; Nonpre

2005
Aspergillus meningitis following spinal anaesthesia for caesarean section in Colombo, Sri Lanka.
    International journal of obstetric anesthesia, 2007, Volume: 16, Issue:3

    Topics: Abducens Nerve Diseases; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Antifungal Agents; Aspe

2007
Amniocentesis results and novel proteomic analysis in a case of occult candidal chorioamnionitis.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2006, Volume: 19, Issue:10

    Topics: Adult; Amniocentesis; Antifungal Agents; Candidiasis; Chorioamnionitis; Female; Fluconazole; Humans;

2006
Plasma nevirapine levels, adverse events and efficacy of antiretroviral therapy among HIV-infected patients concurrently receiving nevirapine-based antiretroviral therapy and fluconazole.
    BMC infectious diseases, 2007, Mar-12, Volume: 7

    Topics: Anti-HIV Agents; Antifungal Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dru

2007
Post partum osteomyelitis due to Cryptococcus neoformans.
    Scandinavian journal of infectious diseases, 2007, Volume: 39, Issue:4

    Topics: Adult; Antifungal Agents; Cryptococcosis; Debridement; Female; Fluconazole; Humans; Injections, Intr

2007
First, do no harm.
    Pediatrics, 2008, Volume: 121, Issue:4

    Topics: Antifungal Agents; Candidiasis; Developmental Disabilities; Female; Fluconazole; Humans; Incidence;

2008
Maternal use of fluconazole and risk of congenital malformations: a Danish population-based cohort study.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 62, Issue:1

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Candidiasis; Cohort Studies; Denmark; Female; Flucon

2008
Nosocomial Torulopsis glabrata fungemia with shock in a pregnant woman successfully treated with high doses of fluconazole and delivery of healthy child.
    Journal of chemotherapy (Florence, Italy), 1995, Volume: 7, Issue:3

    Topics: Adult; Candida; Cross Infection; Female; Fluconazole; Fungemia; Humans; Infant, Newborn; Pregnancy;

1995
Safety of fluconazole in the treatment of vaginal candidiasis. A prescription-event monitoring study, with special reference to the outcome of pregnancy.
    European journal of clinical pharmacology, 1994, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Candidiasis, Vulvovaginal; Child; Child, Preschool; Drug

1994
Fluconazole-induced congenital anomalies in three infants.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Antifungal Agents; Bone and Bones; Coccidioidomycosis; Face; Fem

1996
Teratogenicity of fluconazole.
    The Pediatric infectious disease journal, 1996, Volume: 15, Issue:9

    Topics: Abnormalities, Drug-Induced; Adult; Antifungal Agents; Female; Fluconazole; Humans; Pregnancy

1996
Prospective assessment of pregnancy outcomes after first-trimester exposure to fluconazole.
    American journal of obstetrics and gynecology, 1996, Volume: 175, Issue:6

    Topics: Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Cohort Studies; Female; Fluconazole; Humans; Pr

1996
Fluconazole treatment for vulvovaginal candidiasis during pregnancy.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:1

    Topics: Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Infant, Newborn; M

1997
Congenital anomalies and fluconazole.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1997, Jan-01, Volume: 156, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Antifungal Agents; Candidiasis, Vulvo

1997
[Maternofetal disseminated candidiasis and high-grade prematurity].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1997, Volume: 4, Issue:4

    Topics: Adult; Amphotericin B; Antifungal Agents; Candidiasis; Female; Fluconazole; Humans; Infant, Newborn;

1997
Multiple malformation syndrome following fluconazole use in pregnancy: report of an additional patient.
    American journal of medical genetics, 1997, Oct-31, Volume: 72, Issue:3

    Topics: Abnormalities, Multiple; Adult; Amphotericin B; Antifungal Agents; Coccidioides; Coccidioidomycosis;

1997
Fluconazole teratogenicity.
    Prenatal diagnosis, 1998, Volume: 18, Issue:8

    Topics: Abnormalities, Drug-Induced; Adult; Female; Fertilization; Fluconazole; Humans; Male; Pregnancy; Pre

1998
Pregnancy outcomes after maternal exposure to fluconazole.
    Pharmacotherapy, 1999, Volume: 19, Issue:2

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Female; Fluconazole; Humans; Limb Deformities, Conge

1999
Evidence for digenic inheritance in some cases of Antley-Bixler syndrome?
    Journal of medical genetics, 2000, Volume: 37, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Ankle Joint; Ankylosis; Craniosynostoses; Eye

2000
AIDS activists force attention to fluconazole in South Africa.
    Lancet (London, England), 2000, Nov-04, Volume: 356, Issue:9241

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Drug Ind

2000
Treatment for coccidioidomycosis in pregnancy?
    Postgraduate medicine, 2001, Volume: 109, Issue:3

    Topics: Amphotericin B; Antifungal Agents; Coccidioidomycosis; Erythema Nodosum; Female; Fluconazole; Humans

2001
South Africa cuts agreement for one AIDS drug but ignores another.
    IAPAC monthly, 2001, Volume: 7, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Cost Savings; Drug Indust

2001
First women's HIV conference hears go-for-broke antiretroviral strategy.
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:3

    Topics: Antifungal Agents; Antiviral Agents; CD4 Lymphocyte Count; Counseling; Female; Fluconazole; Health E

1995
Candida sepsis following transcervical chorionic villi sampling.
    Infectious diseases in obstetrics and gynecology, 2001, Volume: 9, Issue:3

    Topics: Adult; Antifungal Agents; Candida albicans; Candidiasis; Chorionic Villi Sampling; Diagnosis, Differ

2001
Bilateral endogenous Candida endophthalmitis after induced abortion.
    Croatian medical journal, 2001, Volume: 42, Issue:6

    Topics: Abortion, Induced; Adult; Amphotericin B; Antifungal Agents; Candidiasis; Endophthalmitis; Eye Infec

2001
Congenital malformations in an infant born to a woman treated with fluconazole.
    The Pediatric infectious disease journal, 1992, Volume: 11, Issue:12

    Topics: Abnormalities, Drug-Induced; Coccidioidomycosis; Congenital Abnormalities; Female; Fluconazole; Huma

1992
Vulvovaginal candidiasis refractory to treatment with fluconazole.
    European journal of obstetrics, gynecology, and reproductive biology, 1992, Mar-23, Volume: 44, Issue:1

    Topics: Adult; Candidiasis, Vulvovaginal; Drug Resistance, Microbial; Female; Fertilization in Vitro; Flucon

1992