fluconazole has been researched along with Pneumonia, Pneumocystis in 19 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Pneumonia, Pneumocystis: A pulmonary disease in humans occurring in immunodeficient or malnourished patients or infants, characterized by DYSPNEA, tachypnea, and HYPOXEMIA. Pneumocystis pneumonia is a frequently seen opportunistic infection in AIDS. It is caused by the fungus PNEUMOCYSTIS JIROVECII. The disease is also found in other MAMMALS where it is caused by related species of Pneumocystis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The test is applied on AIDS prophylaxis and paediatric trials." | 2.69 | Combining mortality and longitudinal measures in clinical trials. ( Finkelstein, DM; Schoenfeld, DA, 1999) |
| "Cryptococcal prostatitis is a rare clinical disease and has never been reported in China." | 1.51 | An AIDS patient with urine retention. ( Cheng, J; Tao, R; Xu, L; Zhao, Q; Zhu, B, 2019) |
| "Pulmonary cryptococcosis is seen in patients with T-cell deficiencies and a diagnosis is made by culture of sputum, BAL, or occasionally of pleural fluid." | 1.43 | A Case of Pneumonia Caused by Pneumocystis Jirovecii and Cryptococcus Neoformans in a Patient with HTLV-1 Associated Adult T- Cell Leukemia/Lymphoma: Occam's Razor Blunted. ( Cunha, BA; Desai, A; Fe, A; Ilowite, J; Mathew, JP, 2016) |
| "Fluconazole is a widely used antifungal agent used to treat Candida spp." | 1.42 | Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: Use of microdialysis. ( Lipman, J; Peake, SL; Roberts, JA; Roberts, MS; Sinnollareddy, MG, 2015) |
| "Pneumocystis jirovecii pneumonia has historically been one of the most common opportunistic pneumonias and life-threatening infectious complications in HIV-infected patients." | 1.33 | [Pneumocystis jirovecii pneumonia: an old disease with a new name]. ( Aleksoniene, R; Ambrozaitis, A; Matulionyte, R; Paulauskiene, R, 2006) |
| "Fluconazole has been prescribed in 7 patients as a permanent suppressive therapy and should be continued indefinitely." | 1.30 | [Pulmonary cryptococcosis during HIV infection. 15 cases]. ( Balloul, E; Cahite, I; Caubarrère, I; Couderc, LJ; Molina, JM; Saimot, AG; Wolff, M, 1997) |
| "Product-limit survival and incidence of AIDS-defining events were calculated as a function of baseline CD4 count." | 1.29 | Logarithmic relationship of the CD4 count to survival in patients with human immunodeficiency virus infection. ( Cal, SX; Haslund, I; Jockusch, JD; Loss, SD; Nightingale, SD; Peterson, DM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (52.63) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Fujie, A | 1 |
| Iwamoto, T | 1 |
| Sato, B | 1 |
| Muramatsu, H | 1 |
| Kasahara, C | 1 |
| Furuta, T | 1 |
| Hori, Y | 1 |
| Hino, M | 1 |
| Hashimoto, S | 1 |
| Wiederhold, NP | 1 |
| Patterson, TF | 1 |
| Rebholz, S | 1 |
| Boal, CWC | 1 |
| Ehrensberger, M | 1 |
| Boyle, R | 1 |
| Cushion, MT | 1 |
| Xu, L | 1 |
| Tao, R | 1 |
| Zhao, Q | 1 |
| Cheng, J | 1 |
| Zhu, B | 1 |
| Yang, JJ | 1 |
| Huang, CH | 1 |
| Liu, CE | 1 |
| Tang, HJ | 1 |
| Yang, CJ | 1 |
| Lee, YC | 1 |
| Lee, KY | 1 |
| Tsai, MS | 1 |
| Lin, SW | 1 |
| Chen, YH | 1 |
| Lu, PL | 1 |
| Hung, CC | 1 |
| Sinnollareddy, MG | 1 |
| Roberts, MS | 1 |
| Lipman, J | 1 |
| Peake, SL | 1 |
| Roberts, JA | 1 |
| Desai, A | 2 |
| Fe, A | 1 |
| Ilowite, J | 1 |
| Cunha, BA | 1 |
| Mathew, JP | 1 |
| Tascini, C | 1 |
| Ferranti, S | 1 |
| Leonildi, A | 1 |
| Menichetti, F | 1 |
| Matulionyte, R | 1 |
| Ambrozaitis, A | 1 |
| Paulauskiene, R | 1 |
| Aleksoniene, R | 1 |
| Clumeck, N | 1 |
| Teira, R | 1 |
| Nightingale, SD | 1 |
| Jockusch, JD | 1 |
| Haslund, I | 1 |
| Cal, SX | 1 |
| Peterson, DM | 1 |
| Loss, SD | 1 |
| Balloul, E | 1 |
| Couderc, LJ | 1 |
| Molina, JM | 1 |
| Cahite, I | 1 |
| Wolff, M | 1 |
| Saimot, AG | 1 |
| Caubarrère, I | 1 |
| Bani-Sadr, F | 1 |
| Hoff, J | 1 |
| Chiffoleau, A | 1 |
| Allavena, C | 1 |
| Raffi, F | 1 |
| Finkelstein, DM | 1 |
| Schoenfeld, DA | 1 |
| Vidal, F | 1 |
| Mirón, M | 1 |
| Sirvent, JJ | 1 |
| Richart, C | 1 |
| Cheng, B | 1 |
| Glick, ME | 1 |
| Wells, C | 1 |
| Lever, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 1 Safety Run-in Study and Phase 1b Randomized, Double Blinded, Placebo Controlled Trial[NCT05695521] | Phase 1 | 66 participants (Anticipated) | Interventional | 2023-04-03 | Recruiting | ||
| A Randomized Study of the MitraClip Device in Heart Failure Patients With Clinically Significant Functional Mitral Regurgitation[NCT01772108] | 42 participants (Actual) | Interventional | 2013-04-30 | Terminated (stopped due to As recruitment rate was lower than anticipated) | |||
| Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole and Dapsone and Their Hydroxylamine Metabolites[NCT00000826] | Phase 1 | 48 participants | Interventional | Completed | |||
| A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected Children[NCT00000637] | Phase 3 | 819 participants | Interventional | Completed | |||
| Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)[NCT00000676] | Phase 3 | 500 participants | Interventional | Completed | |||
| A Randomized Trial of Three Anti-Pneumocystis Agents Plus Zidovudine for the Primary Prevention of Serious Infections in Patients With Advanced HIV Infection[NCT00000991] | Phase 3 | 600 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for fluconazole and Pneumonia, Pneumocystis
| Article | Year |
|---|---|
Combining mortality and longitudinal measures in clinical trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi | 1999 |
Combining mortality and longitudinal measures in clinical trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi | 1999 |
Combining mortality and longitudinal measures in clinical trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi | 1999 |
Combining mortality and longitudinal measures in clinical trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi | 1999 |
18 other studies available for fluconazole and Pneumonia, Pneumocystis
| Article | Year |
|---|---|
FR131535, a novel water-soluble echinocandin-like lipopeptide: synthesis and biological properties.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Bronchogenic Cyst; Candida albicans; Candidiasis; | 2001 |
The Antifungal and Anti-Pneumocystis Activities of the Novel Compound A3IS (Mycosinate).
Topics: Antifungal Agents; Fluconazole; Fungi; Humans; Microbial Sensitivity Tests; Pneumocystis; Pneumonia, | 2022 |
An AIDS patient with urine retention.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; China; Cryptococcosis; Cryptococcus neofor | 2019 |
Multicenter study of trimethoprim/sulfamethoxazole-related hepatotoxicity: incidence and associated factors among HIV-infected patients treated for Pneumocystis jirovecii pneumonia.
Topics: Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Anti-Infective Agents; Arylamine N-Acetyltransferas | 2014 |
Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: Use of microdialysis.
Topics: Adult; Antifungal Agents; Chromatography; Critical Illness; Extracellular Fluid; Fluconazole; HIV In | 2015 |
A Case of Pneumonia Caused by Pneumocystis Jirovecii and Cryptococcus Neoformans in a Patient with HTLV-1 Associated Adult T- Cell Leukemia/Lymphoma: Occam's Razor Blunted.
Topics: Adrenal Cortex Hormones; Anti-Infective Agents; Antifungal Agents; Cryptococcosis; Cryptococcus neof | 2016 |
Breakthrough Fusarium sp probable pneumonia during fluconazole therapy in an AIDS patient with diabetes, candidemia, Pneumocystis carinii pneumonia and cytomegalovirus disseminated infection.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis; Cytomegalovirus Infections; D | 2006 |
[Pneumocystis jirovecii pneumonia: an old disease with a new name].
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents, Urinary; Antifungal Agents; Drug Combi | 2006 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifunga | 1995 |
Primary prophylaxis against opportunistic infections in patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Clotrimazole; Dapsone; Fluconazole; Humans; Mycoses; Pentamid | 1995 |
[Treatment and prevention of main infections associated with HIV].
Topics: Adrenal Cortex Hormones; Amphotericin B; Controlled Clinical Trials as Topic; Cryptococcosis; Flucon | 1994 |
Logarithmic relationship of the CD4 count to survival in patients with human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Age Factors; AIDS-Related Opportunistic Infections; CD4-P | 1993 |
[Pulmonary cryptococcosis during HIV infection. 15 cases].
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Cryptococcosis; Flu | 1997 |
[Severe hypercalcemia in a patient treated with fluconazole and rifampicin].
Topics: Adult; AIDS-Related Opportunistic Infections; Antibiotics, Antitubercular; Antifungal Agents; Female | 1998 |
Central nervous system pneumocystosis in AIDS: antemortem diagnosis and successful treatment.
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Anti-HIV Agents; Antifungal Agents; Ce | 2000 |
Preventing opportunistic infections.
Topics: Acyclovir; AIDS-Related Opportunistic Infections; Clarithromycin; Clindamycin; Clinical Trials as To | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
Dose-dependent fluconazole hepatotoxicity proven on biopsy and rechallenge.
Topics: Candidiasis, Oral; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug In | 1992 |