Page last updated: 2024-10-27

fluconazole and P carinii Pneumonia

fluconazole has been researched along with P carinii Pneumonia in 19 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Research Excerpts

ExcerptRelevanceReference
"The test is applied on AIDS prophylaxis and paediatric trials."2.69Combining mortality and longitudinal measures in clinical trials. ( Finkelstein, DM; Schoenfeld, DA, 1999)
"Cryptococcal prostatitis is a rare clinical disease and has never been reported in China."1.51An AIDS patient with urine retention. ( Cheng, J; Tao, R; Xu, L; Zhao, Q; Zhu, B, 2019)
"Pulmonary cryptococcosis is seen in patients with T-cell deficiencies and a diagnosis is made by culture of sputum, BAL, or occasionally of pleural fluid."1.43A Case of Pneumonia Caused by Pneumocystis Jirovecii and Cryptococcus Neoformans in a Patient with HTLV-1 Associated Adult T- Cell Leukemia/Lymphoma: Occam's Razor Blunted. ( Cunha, BA; Desai, A; Fe, A; Ilowite, J; Mathew, JP, 2016)
"Fluconazole is a widely used antifungal agent used to treat Candida spp."1.42Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: Use of microdialysis. ( Lipman, J; Peake, SL; Roberts, JA; Roberts, MS; Sinnollareddy, MG, 2015)
"Pneumocystis jirovecii pneumonia has historically been one of the most common opportunistic pneumonias and life-threatening infectious complications in HIV-infected patients."1.33[Pneumocystis jirovecii pneumonia: an old disease with a new name]. ( Aleksoniene, R; Ambrozaitis, A; Matulionyte, R; Paulauskiene, R, 2006)
"Fluconazole has been prescribed in 7 patients as a permanent suppressive therapy and should be continued indefinitely."1.30[Pulmonary cryptococcosis during HIV infection. 15 cases]. ( Balloul, E; Cahite, I; Caubarrère, I; Couderc, LJ; Molina, JM; Saimot, AG; Wolff, M, 1997)
"Product-limit survival and incidence of AIDS-defining events were calculated as a function of baseline CD4 count."1.29Logarithmic relationship of the CD4 count to survival in patients with human immunodeficiency virus infection. ( Cal, SX; Haslund, I; Jockusch, JD; Loss, SD; Nightingale, SD; Peterson, DM, 1993)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (52.63)18.2507
2000's4 (21.05)29.6817
2010's4 (21.05)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Fujie, A1
Iwamoto, T1
Sato, B1
Muramatsu, H1
Kasahara, C1
Furuta, T1
Hori, Y1
Hino, M1
Hashimoto, S1
Wiederhold, NP1
Patterson, TF1
Rebholz, S1
Boal, CWC1
Ehrensberger, M1
Boyle, R1
Cushion, MT1
Xu, L1
Tao, R1
Zhao, Q1
Cheng, J1
Zhu, B1
Yang, JJ1
Huang, CH1
Liu, CE1
Tang, HJ1
Yang, CJ1
Lee, YC1
Lee, KY1
Tsai, MS1
Lin, SW1
Chen, YH1
Lu, PL1
Hung, CC1
Sinnollareddy, MG1
Roberts, MS1
Lipman, J1
Peake, SL1
Roberts, JA1
Desai, A2
Fe, A1
Ilowite, J1
Cunha, BA1
Mathew, JP1
Tascini, C1
Ferranti, S1
Leonildi, A1
Menichetti, F1
Matulionyte, R1
Ambrozaitis, A1
Paulauskiene, R1
Aleksoniene, R1
Clumeck, N1
Teira, R1
Nightingale, SD1
Jockusch, JD1
Haslund, I1
Cal, SX1
Peterson, DM1
Loss, SD1
Balloul, E1
Couderc, LJ1
Molina, JM1
Cahite, I1
Wolff, M1
Saimot, AG1
Caubarrère, I1
Bani-Sadr, F1
Hoff, J1
Chiffoleau, A1
Allavena, C1
Raffi, F1
Finkelstein, DM1
Schoenfeld, DA1
Vidal, F1
Mirón, M1
Sirvent, JJ1
Richart, C1
Cheng, B1
Glick, ME1
Wells, C1
Lever, AM1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 1 Safety Run-in Study and Phase 1b Randomized, Double Blinded, Placebo Controlled Trial[NCT05695521]Phase 166 participants (Anticipated)Interventional2023-04-03Recruiting
A Randomized Study of the MitraClip Device in Heart Failure Patients With Clinically Significant Functional Mitral Regurgitation[NCT01772108]42 participants (Actual)Interventional2013-04-30Terminated (stopped due to As recruitment rate was lower than anticipated)
Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole and Dapsone and Their Hydroxylamine Metabolites[NCT00000826]Phase 148 participants InterventionalCompleted
A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected Children[NCT00000637]Phase 3819 participants InterventionalCompleted
Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)[NCT00000676]Phase 3500 participants InterventionalCompleted
A Randomized Trial of Three Anti-Pneumocystis Agents Plus Zidovudine for the Primary Prevention of Serious Infections in Patients With Advanced HIV Infection[NCT00000991]Phase 3600 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for fluconazole and P carinii Pneumonia

ArticleYear
Combining mortality and longitudinal measures in clinical trials.
    Statistics in medicine, 1999, Jun-15, Volume: 18, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi

1999
Combining mortality and longitudinal measures in clinical trials.
    Statistics in medicine, 1999, Jun-15, Volume: 18, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi

1999
Combining mortality and longitudinal measures in clinical trials.
    Statistics in medicine, 1999, Jun-15, Volume: 18, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi

1999
Combining mortality and longitudinal measures in clinical trials.
    Statistics in medicine, 1999, Jun-15, Volume: 18, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Candi

1999

Other Studies

18 other studies available for fluconazole and P carinii Pneumonia

ArticleYear
FR131535, a novel water-soluble echinocandin-like lipopeptide: synthesis and biological properties.
    Bioorganic & medicinal chemistry letters, 2001, Feb-12, Volume: 11, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Bronchogenic Cyst; Candida albicans; Candidiasis;

2001
The Antifungal and Anti-Pneumocystis Activities of the Novel Compound A3IS (Mycosinate).
    Antimicrobial agents and chemotherapy, 2022, 08-16, Volume: 66, Issue:8

    Topics: Antifungal Agents; Fluconazole; Fungi; Humans; Microbial Sensitivity Tests; Pneumocystis; Pneumonia,

2022
An AIDS patient with urine retention.
    BMC infectious diseases, 2019, Dec-12, Volume: 19, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; China; Cryptococcosis; Cryptococcus neofor

2019
Multicenter study of trimethoprim/sulfamethoxazole-related hepatotoxicity: incidence and associated factors among HIV-infected patients treated for Pneumocystis jirovecii pneumonia.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Anti-Infective Agents; Arylamine N-Acetyltransferas

2014
Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: Use of microdialysis.
    International journal of antimicrobial agents, 2015, Volume: 46, Issue:1

    Topics: Adult; Antifungal Agents; Chromatography; Critical Illness; Extracellular Fluid; Fluconazole; HIV In

2015
A Case of Pneumonia Caused by Pneumocystis Jirovecii and Cryptococcus Neoformans in a Patient with HTLV-1 Associated Adult T- Cell Leukemia/Lymphoma: Occam's Razor Blunted.
    Connecticut medicine, 2016, Volume: 80, Issue:2

    Topics: Adrenal Cortex Hormones; Anti-Infective Agents; Antifungal Agents; Cryptococcosis; Cryptococcus neof

2016
Breakthrough Fusarium sp probable pneumonia during fluconazole therapy in an AIDS patient with diabetes, candidemia, Pneumocystis carinii pneumonia and cytomegalovirus disseminated infection.
    Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis; Cytomegalovirus Infections; D

2006
[Pneumocystis jirovecii pneumonia: an old disease with a new name].
    Medicina (Kaunas, Lithuania), 2006, Volume: 42, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents, Urinary; Antifungal Agents; Drug Combi

2006
Drugs for AIDS and associated infections.
    The Medical letter on drugs and therapeutics, 1995, Oct-13, Volume: 37, Issue:959

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifunga

1995
Primary prophylaxis against opportunistic infections in patients with AIDS.
    The New England journal of medicine, 1995, Mar-16, Volume: 332, Issue:11

    Topics: AIDS-Related Opportunistic Infections; Clotrimazole; Dapsone; Fluconazole; Humans; Mycoses; Pentamid

1995
[Treatment and prevention of main infections associated with HIV].
    Medicina clinica, 1994, Dec-10, Volume: 103, Issue:20

    Topics: Adrenal Cortex Hormones; Amphotericin B; Controlled Clinical Trials as Topic; Cryptococcosis; Flucon

1994
Logarithmic relationship of the CD4 count to survival in patients with human immunodeficiency virus infection.
    Archives of internal medicine, 1993, Jun-14, Volume: 153, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Age Factors; AIDS-Related Opportunistic Infections; CD4-P

1993
[Pulmonary cryptococcosis during HIV infection. 15 cases].
    Revue des maladies respiratoires, 1997, Volume: 14, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Cryptococcosis; Flu

1997
[Severe hypercalcemia in a patient treated with fluconazole and rifampicin].
    Presse medicale (Paris, France : 1983), 1998, May-16, Volume: 27, Issue:18

    Topics: Adult; AIDS-Related Opportunistic Infections; Antibiotics, Antitubercular; Antifungal Agents; Female

1998
Central nervous system pneumocystosis in AIDS: antemortem diagnosis and successful treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 30, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Anti-HIV Agents; Antifungal Agents; Ce

2000
Preventing opportunistic infections.
    PI perspective, 1995, Issue:no 16

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Clarithromycin; Clindamycin; Clinical Trials as To

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
Dose-dependent fluconazole hepatotoxicity proven on biopsy and rechallenge.
    The Journal of infection, 1992, Volume: 24, Issue:1

    Topics: Candidiasis, Oral; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug In

1992