fluconazole has been researched along with MODS in 9 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although fluconazole is the therapy of choice for patients in the intensive care setting with Candida infections, two patients with multiple organ failure who received high-dose fluconazole appeared to develop adrenal insufficiency." | 7.71 | Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients. ( Albert, SG; DeLeon, MJ; Silverberg, AB, 2001) |
| "To demonstrate whether fluconazole reduces multiple organ failure and mortality in early septic shock (<24 hrs)." | 5.10 | Fluconazole improves survival in septic shock: a randomized double-blind prospective study. ( Al Omar, NF; Jacobs, S; Price Evans, DA; Tariq, M, 2003) |
| "Although fluconazole is the therapy of choice for patients in the intensive care setting with Candida infections, two patients with multiple organ failure who received high-dose fluconazole appeared to develop adrenal insufficiency." | 3.71 | Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients. ( Albert, SG; DeLeon, MJ; Silverberg, AB, 2001) |
| "The mortality of candidemia is affected by the underlying conditions, causative agents and the initial management." | 1.51 | Mortality and risk factor analysis for Candida blood stream infection: A multicenter study. ( Ide, K; Kato, H; Matsuno, K; Nakajima, H; Shimizu, H; Sugiyama, Y; Suido, Y; Yoshimura, Y, 2019) |
| "Here, we present a Fournier's gangrene case caused by Candida albicans." | 1.35 | [Fournier's gangrene caused by Candida albicans]. ( Aslan, A; Cetin, M; Temiz, M, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jakkidi, M | 1 |
| Basmadjian, C | 1 |
| Roy, S | 1 |
| Kato, H | 1 |
| Yoshimura, Y | 1 |
| Suido, Y | 1 |
| Shimizu, H | 1 |
| Ide, K | 1 |
| Sugiyama, Y | 1 |
| Matsuno, K | 1 |
| Nakajima, H | 1 |
| Islam, S | 1 |
| Singer, M | 1 |
| Kulhanjian, JA | 1 |
| Temiz, M | 1 |
| Cetin, M | 1 |
| Aslan, A | 1 |
| Jacobs, S | 1 |
| Price Evans, DA | 1 |
| Tariq, M | 1 |
| Al Omar, NF | 1 |
| Negroni, R | 1 |
| Maiolo, E | 1 |
| Arechavala, AI | 1 |
| Bianchi, MH | 1 |
| Santiso, G | 1 |
| Götzinger, P | 1 |
| Wamser, P | 1 |
| Barlan, M | 1 |
| Sautner, T | 1 |
| Jakesz, R | 1 |
| Függer, R | 1 |
| Albert, SG | 1 |
| DeLeon, MJ | 1 |
| Silverberg, AB | 1 |
| Buchta, V | 1 |
| Zák, P | 1 |
| Kohout, A | 1 |
| Otcenásek, M | 1 |
2 reviews available for fluconazole and MODS
| Article | Year |
|---|---|
Toxic epidermal necrolysis in a neonate receiving fluconazole.
Topics: Disease Progression; Fatal Outcome; Female; Fluconazole; Humans; Infant, Newborn; Infant, Premature; | 2014 |
Case report. Disseminated infection of Blastoschizomyces capitatus in a patient with acute myelocytic leukaemia.
Topics: Amphotericin B; Antifungal Agents; Fatal Outcome; Fluconazole; Humans; Leukemia, Myeloid, Acute; Mal | 2001 |
1 trial available for fluconazole and MODS
| Article | Year |
|---|---|
Fluconazole improves survival in septic shock: a randomized double-blind prospective study.
Topics: Adult; Aged; Antifungal Agents; Cross Infection; Double-Blind Method; Female; Fluconazole; Hospital | 2003 |
6 other studies available for fluconazole and MODS
| Article | Year |
|---|---|
An illusion of septic shock: acute generalised exanthematous pustulosis with multiorgan dysfunction.
Topics: Acute Disease; Acute Generalized Exanthematous Pustulosis; Anti-Bacterial Agents; Anti-Inflammatory | 2017 |
Mortality and risk factor analysis for Candida blood stream infection: A multicenter study.
Topics: Age Factors; Aged; Anti-Bacterial Agents; Antifungal Agents; Candida; Candidemia; Female; Fluconazol | 2019 |
[Fournier's gangrene caused by Candida albicans].
Topics: Antifungal Agents; Candida albicans; Candidiasis; Debridement; Diabetes Complications; Diagnosis, Di | 2008 |
[Clinical cases in medical mycology. Case no. 32].
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Aspergillosis; Bacteremia; Bronchoalveolar | 2008 |
Candida infection of local necrosis in severe acute pancreatitis is associated with increased mortality.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Candidiasis; Female; Fluconazole; Hum | 2000 |
Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Aged; Antifungal Agents; Candidiasis; Cosyntropi | 2001 |