Page last updated: 2024-10-27

fluconazole and MODS

fluconazole has been researched along with MODS in 9 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Research Excerpts

ExcerptRelevanceReference
"Although fluconazole is the therapy of choice for patients in the intensive care setting with Candida infections, two patients with multiple organ failure who received high-dose fluconazole appeared to develop adrenal insufficiency."7.71Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients. ( Albert, SG; DeLeon, MJ; Silverberg, AB, 2001)
"To demonstrate whether fluconazole reduces multiple organ failure and mortality in early septic shock (<24 hrs)."5.10Fluconazole improves survival in septic shock: a randomized double-blind prospective study. ( Al Omar, NF; Jacobs, S; Price Evans, DA; Tariq, M, 2003)
"Although fluconazole is the therapy of choice for patients in the intensive care setting with Candida infections, two patients with multiple organ failure who received high-dose fluconazole appeared to develop adrenal insufficiency."3.71Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients. ( Albert, SG; DeLeon, MJ; Silverberg, AB, 2001)
"The mortality of candidemia is affected by the underlying conditions, causative agents and the initial management."1.51Mortality and risk factor analysis for Candida blood stream infection: A multicenter study. ( Ide, K; Kato, H; Matsuno, K; Nakajima, H; Shimizu, H; Sugiyama, Y; Suido, Y; Yoshimura, Y, 2019)
"Here, we present a Fournier's gangrene case caused by Candida albicans."1.35[Fournier's gangrene caused by Candida albicans]. ( Aslan, A; Cetin, M; Temiz, M, 2008)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jakkidi, M1
Basmadjian, C1
Roy, S1
Kato, H1
Yoshimura, Y1
Suido, Y1
Shimizu, H1
Ide, K1
Sugiyama, Y1
Matsuno, K1
Nakajima, H1
Islam, S1
Singer, M1
Kulhanjian, JA1
Temiz, M1
Cetin, M1
Aslan, A1
Jacobs, S1
Price Evans, DA1
Tariq, M1
Al Omar, NF1
Negroni, R1
Maiolo, E1
Arechavala, AI1
Bianchi, MH1
Santiso, G1
Götzinger, P1
Wamser, P1
Barlan, M1
Sautner, T1
Jakesz, R1
Függer, R1
Albert, SG1
DeLeon, MJ1
Silverberg, AB1
Buchta, V1
Zák, P1
Kohout, A1
Otcenásek, M1

Reviews

2 reviews available for fluconazole and MODS

ArticleYear
Toxic epidermal necrolysis in a neonate receiving fluconazole.
    Journal of perinatology : official journal of the California Perinatal Association, 2014, Volume: 34, Issue:10

    Topics: Disease Progression; Fatal Outcome; Female; Fluconazole; Humans; Infant, Newborn; Infant, Premature;

2014
Case report. Disseminated infection of Blastoschizomyces capitatus in a patient with acute myelocytic leukaemia.
    Mycoses, 2001, Volume: 44, Issue:11-12

    Topics: Amphotericin B; Antifungal Agents; Fatal Outcome; Fluconazole; Humans; Leukemia, Myeloid, Acute; Mal

2001

Trials

1 trial available for fluconazole and MODS

ArticleYear
Fluconazole improves survival in septic shock: a randomized double-blind prospective study.
    Critical care medicine, 2003, Volume: 31, Issue:7

    Topics: Adult; Aged; Antifungal Agents; Cross Infection; Double-Blind Method; Female; Fluconazole; Hospital

2003

Other Studies

6 other studies available for fluconazole and MODS

ArticleYear
An illusion of septic shock: acute generalised exanthematous pustulosis with multiorgan dysfunction.
    BMJ case reports, 2017, Aug-02, Volume: 2017

    Topics: Acute Disease; Acute Generalized Exanthematous Pustulosis; Anti-Bacterial Agents; Anti-Inflammatory

2017
Mortality and risk factor analysis for Candida blood stream infection: A multicenter study.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2019, Volume: 25, Issue:5

    Topics: Age Factors; Aged; Anti-Bacterial Agents; Antifungal Agents; Candida; Candidemia; Female; Fluconazol

2019
[Fournier's gangrene caused by Candida albicans].
    Mikrobiyoloji bulteni, 2008, Volume: 42, Issue:4

    Topics: Antifungal Agents; Candida albicans; Candidiasis; Debridement; Diabetes Complications; Diagnosis, Di

2008
[Clinical cases in medical mycology. Case no. 32].
    Revista iberoamericana de micologia, 2008, Volume: 25, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Aspergillosis; Bacteremia; Bronchoalveolar

2008
Candida infection of local necrosis in severe acute pancreatitis is associated with increased mortality.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Candidiasis; Female; Fluconazole; Hum

2000
Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients.
    Critical care medicine, 2001, Volume: 29, Issue:3

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Aged; Antifungal Agents; Candidiasis; Cosyntropi

2001