fluconazole has been researched along with Long QT Syndrome in 13 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present the occurrence of 'torsade de pointes' induced by the combination of peroperative fluconazole administration and sevoflurane anesthesia in a patient with 'long QT syndrome' (LQTS) scheduled for resection of a sacral abscess." | 7.77 | Torsade de pointes during sevoflurane anesthesia and fluconazole infusion in a patient with long QT syndrome. A case report. ( Bracke, FA; Tacken, MC; Van Zundert, AA, 2011) |
| "We present the occurrence of 'torsade de pointes' induced by the combination of peroperative fluconazole administration and sevoflurane anesthesia in a patient with 'long QT syndrome' (LQTS) scheduled for resection of a sacral abscess." | 3.77 | Torsade de pointes during sevoflurane anesthesia and fluconazole infusion in a patient with long QT syndrome. A case report. ( Bracke, FA; Tacken, MC; Van Zundert, AA, 2011) |
| " Participants received standard care - amphotericin combined with fluconazole for the first 2 weeks - or standard care plus tamoxifen 300 mg/day." | 3.01 | An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis. ( Beardsley, J; Binh, TQ; Chau, NVV; Day, JN; Geskus, R; Hope, W; Hung, LQ; Kestelyn, E; Krysan, D; Lalloo, DG; Lan, NPH; Mai, NTH; Ngan, NTT; Phu, NH; Tai, LTH; Thanh Hoang Le, N; Thwaites, GE; Trieu, PH; Tung, NLN; Van Anh, D; Van, NTT; Vi Vi, NN; White, NJ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Ngan, NTT | 1 |
| Thanh Hoang Le, N | 1 |
| Vi Vi, NN | 1 |
| Van, NTT | 1 |
| Mai, NTH | 1 |
| Van Anh, D | 1 |
| Trieu, PH | 1 |
| Lan, NPH | 1 |
| Phu, NH | 1 |
| Chau, NVV | 1 |
| Lalloo, DG | 1 |
| Hope, W | 1 |
| Beardsley, J | 1 |
| White, NJ | 1 |
| Geskus, R | 1 |
| Thwaites, GE | 1 |
| Krysan, D | 1 |
| Tai, LTH | 1 |
| Kestelyn, E | 1 |
| Binh, TQ | 1 |
| Hung, LQ | 1 |
| Tung, NLN | 1 |
| Day, JN | 1 |
| Ünal Yüksekgönül, A | 1 |
| Ertuğrul, İ | 1 |
| Karagöz, T | 1 |
| Berger, FA | 1 |
| Monadian, N | 1 |
| de Groot, NMS | 1 |
| Santbergen, B | 1 |
| van der Sijs, H | 1 |
| Becker, ML | 1 |
| Broers, AEC | 1 |
| van Gelder, T | 1 |
| van den Bemt, PMLA | 1 |
| Tilton, JJ | 1 |
| Sadr, R | 1 |
| Groo, VL | 1 |
| Buch, T | 1 |
| Andersen, SE | 1 |
| Wang, J | 1 |
| Wang, G | 1 |
| Quan, X | 1 |
| Ruan, L | 1 |
| Liu, Y | 1 |
| Ruan, Y | 1 |
| Liu, N | 1 |
| Zhang, C | 1 |
| Bai, R | 1 |
| Vandael, E | 1 |
| Vandenberk, B | 1 |
| Vandenberghe, J | 1 |
| Spriet, I | 1 |
| Willems, R | 1 |
| Foulon, V | 1 |
| Tacken, MC | 1 |
| Bracke, FA | 1 |
| Van Zundert, AA | 1 |
| Zeuli, JD | 1 |
| Wilson, JW | 1 |
| Estes, LL | 1 |
| Hrovatin, E | 1 |
| Zardo, F | 1 |
| Brieda, M | 1 |
| Dametto, E | 1 |
| Piazza, R | 1 |
| Antonini-Canterin, F | 1 |
| Cassin, M | 1 |
| Meneguzzo, N | 1 |
| Viel, E | 1 |
| Lestuzzi, C | 1 |
| Di Gennaro, G | 1 |
| Nicolosi, GL | 1 |
| Hinterseer, M | 1 |
| Irlbeck, M | 1 |
| Ney, L | 1 |
| Beckmann, BM | 1 |
| Pfeufer, A | 1 |
| Steinbeck, G | 1 |
| Kaab, S | 1 |
| Wassmann, S | 1 |
| Nickenig, G | 1 |
| Böhm, M | 1 |
| Dorsey, ST | 1 |
| Biblo, LA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial of Tamoxifen Combined With Amphotericin B and Fluconazole for Cryptococcal Meningitis[NCT03112031] | Phase 2 | 50 participants (Actual) | Interventional | 2017-10-10 | Completed | ||
| Risk of QT-prolongation and Torsade de Pointes in Patients Treated With Acute Medication in a University Hospital[NCT02068170] | 178 participants (Actual) | Observational | 2014-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for fluconazole and Long QT Syndrome
| Article | Year |
|---|---|
An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis.
Topics: Adult; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Drug Therapy, Combination; Female | 2021 |
12 other studies available for fluconazole and Long QT Syndrome
| Article | Year |
|---|---|
Fluconazole-associated QT interval prolongation and Torsades de Pointes in a paediatric patient.
Topics: Adolescent; Child; Electrocardiography; Female; Fluconazole; Humans; Long QT Syndrome; Tachycardia, | 2021 |
QTc prolongation during ciprofloxacin and fluconazole combination therapy: prevalence and associated risk factors.
Topics: Ciprofloxacin; Drug Therapy, Combination; Electrocardiography; Female; Fluconazole; Heart Rate; Huma | 2018 |
Concomitant use of levofloxacin and fluconazole leading to possible torsades de pointes.
Topics: Adult; Electrocardiography; Female; Fluconazole; Humans; Levofloxacin; Long QT Syndrome; Risk Factor | 2019 |
[Combination therapy with fluconazole and other QTc-prolonging drugs increase the QTc interval].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antifungal Agents; Clarithromycin; | 2015 |
Fluconazole-induced long QT syndrome via impaired human ether-a-go-go-related gene (hERG) protein trafficking in rabbits.
Topics: Animals; Disease Models, Animal; Electrocardiography; ERG1 Potassium Channel; Female; Fluconazole; H | 2017 |
Development of a risk score for QTc-prolongation: the RISQ-PATH study.
Topics: Aged; Female; Fluconazole; Haloperidol; Humans; Levofloxacin; Long QT Syndrome; Male; Models, Statis | 2017 |
Torsade de pointes during sevoflurane anesthesia and fluconazole infusion in a patient with long QT syndrome. A case report.
Topics: Abscess; Aged; Anesthetics, Inhalation; Antifungal Agents; Electrocardiography; Female; Fluconazole; | 2011 |
Effect of combined fluoroquinolone and azole use on QT prolongation in hematology patients.
Topics: Adult; Aged; Antifungal Agents; Drug Administration Schedule; Drug Therapy, Combination; Electrocard | 2013 |
[Long QT and torsade de pointes in a patient with acquired human immunodeficiency virus infection in multitherapy with drugs affecting cytochrome P450].
Topics: Acquired Immunodeficiency Syndrome; Analgesics, Opioid; Antifungal Agents; Antiretroviral Therapy, H | 2004 |
Acute respiratory distress syndrome with transiently impaired left ventricular function and Torsades de Pointes arrhythmia unmasking congenital long QT syndrome in a 25-yr-old woman.
Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Echocardiography; ERG1 Potassium Channel; Erythromy | 2006 |
Long QT syndrome and torsade de pointes in a patient receiving fluconazole.
Topics: Antifungal Agents; Female; Fluconazole; Humans; Long QT Syndrome; Middle Aged; Torsades de Pointes | 1999 |
Prolonged QT interval and torsades de pointes caused by the combination of fluconazole and amitriptyline.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antifungal Agents; Drug Interactions; Electrocardio | 2000 |