fluconazole has been researched along with Leukocytopenia in 6 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Efficacies of fluconazole, a new triazole antifungal agent, were evaluated in 11 cases of systemic mycoses (1 case each of candiduria, pulmonary cryptococcosis, pulmonary aspergillosis, pulmonary penicilliosis and suspected fungal pulmonary infection, and 3 cases each of candidemia and Candida endophthalmitis)." | 7.67 | [Fluconazole treatment of systemic mycoses]. ( Ebe, T; Hamamoto, T; Hibiya, I; Inagaki, M; Isonuma, H; Kohara, T; Matsumura, M; Mori, T; Takahashi, M; Watanabe, K, 1989) |
| "Efficacies of fluconazole, a new triazole antifungal agent, were evaluated in 11 cases of systemic mycoses (1 case each of candiduria, pulmonary cryptococcosis, pulmonary aspergillosis, pulmonary penicilliosis and suspected fungal pulmonary infection, and 3 cases each of candidemia and Candida endophthalmitis)." | 3.67 | [Fluconazole treatment of systemic mycoses]. ( Ebe, T; Hamamoto, T; Hibiya, I; Inagaki, M; Isonuma, H; Kohara, T; Matsumura, M; Mori, T; Takahashi, M; Watanabe, K, 1989) |
| "Fluconazole used for the treatment of mice infected with C." | 1.33 | Prophylactic use of liposomized tuftsin enhances the susceptibility of Candida albicans to fluconazole in leukopenic mice. ( Khan, A; Khan, MA; Owais, M, 2006) |
| "Fluconazole was labelled with (99m)Tc and radiochemical analysis showed less than 5% impurities." | 1.31 | Technetium-99m labelled fluconazole and antimicrobial peptides for imaging of Candida albicans and Aspergillus fumigatus infections. ( Lupetti, A; Mazzi, U; Nibbering, PH; Pauwels, EK; Welling, MM, 2002) |
| " In immunocompetent mice, the dosage of AmB-DOC was limited by toxicity, resulting in a maximum tolerated dosage (MTD) of 0." | 1.29 | Efficacies of amphotericin B-desoxycholate (Fungizone), liposomal amphotericin B (AmBisome) and fluconazole in the treatment of systemic candidosis in immunocompetent and leucopenic mice. ( Bakker-Woudenberg, IA; van den Heuvel-de Groot, C; van Etten, EW, 1993) |
| "For amphotericin B there was a good correlation between in vitro and in vivo efficacy, but this was not true of the triazole derivatives." | 1.28 | In vitro and in vivo activities of Sch 39304, fluconazole, and amphotericin B against Histoplasma capsulatum. ( Kobayashi, GS; Medoff, G; Rinaldi, MG; Travis, SJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, MA | 1 |
| Khan, A | 1 |
| Owais, M | 1 |
| van Etten, EW | 1 |
| van den Heuvel-de Groot, C | 1 |
| Bakker-Woudenberg, IA | 1 |
| Bruserud, O | 1 |
| Lupetti, A | 1 |
| Welling, MM | 1 |
| Mazzi, U | 1 |
| Nibbering, PH | 1 |
| Pauwels, EK | 1 |
| Kobayashi, GS | 1 |
| Travis, SJ | 1 |
| Rinaldi, MG | 1 |
| Medoff, G | 1 |
| Mori, T | 1 |
| Matsumura, M | 1 |
| Ebe, T | 1 |
| Takahashi, M | 1 |
| Kohara, T | 1 |
| Inagaki, M | 1 |
| Isonuma, H | 1 |
| Hibiya, I | 1 |
| Hamamoto, T | 1 |
| Watanabe, K | 1 |
6 other studies available for fluconazole and Leukocytopenia
| Article | Year |
|---|---|
Prophylactic use of liposomized tuftsin enhances the susceptibility of Candida albicans to fluconazole in leukopenic mice.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Colony Count, Microbial; Drug Resistance, | 2006 |
Efficacies of amphotericin B-desoxycholate (Fungizone), liposomal amphotericin B (AmBisome) and fluconazole in the treatment of systemic candidosis in immunocompetent and leucopenic mice.
Topics: Amphotericin B; Animals; Candidiasis; Deoxycholic Acid; Drug Carriers; Drug Combinations; Female; Fl | 1993 |
Effects of azoles on human acute myelogenous leukemia blasts and T lymphocytes derived from acute leukemia patients with chemotherapy-induced cytopenia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antifungal Agents; CD4-Positive T-Lymphocytes; CD8-Positive | 2001 |
Technetium-99m labelled fluconazole and antimicrobial peptides for imaging of Candida albicans and Aspergillus fumigatus infections.
Topics: Animals; Aspergillosis; Aspergillus fumigatus; Candidiasis; Diagnosis, Differential; Fluconazole; Hu | 2002 |
In vitro and in vivo activities of Sch 39304, fluconazole, and amphotericin B against Histoplasma capsulatum.
Topics: Amphotericin B; Animals; Antifungal Agents; Female; Fluconazole; Histoplasma; Histoplasmosis; Leukop | 1990 |
[Fluconazole treatment of systemic mycoses].
Topics: Adolescent; Adult; Aged; Anorexia; Antifungal Agents; Candidiasis; Drug Evaluation; Drug Tolerance; | 1989 |