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fluconazole and Leukemia, Promyelocytic, Acute

fluconazole has been researched along with Leukemia, Promyelocytic, Acute in 10 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.

Research Excerpts

ExcerptRelevanceReference
" Here, we discuss about the diagnosis and treatment process of the IIH emerging in a young acute promyelocytic leukemia (APL) case with the ATRA impact, which can be increased by posaconazole."8.12Papilledema and idiopathic intracranial hypertension due to the possible potentiation of ATRA by posaconazole in a case of acute promyelocytic leukemia. ( Atas, U; Aydin Ersoy, M; Iltar, U; Salim, O; Turkoglu, EB; Yucel, OK, 2022)
"We describe 2 patients with acute promyelocytic leukemia (APL) in whom torsade de pointes (TdP) developed during treatment with arsenic trioxide."7.73Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy. ( Kobayashi, M; Naito, K; Nakamura, S; Ohnishi, K; Ohno, R; Sahara, N; Shigeno, K; Shinjo, K; Takeshita, A; Tobita, T, 2006)
"All-trans-retinoic acid induces acute promyelocytic leukemia cell differentiation in vitro, and it produces greater than 90% complete remissions in patients with acute promyelocytic leukemia."5.29Inhibition of all-trans-retinoic acid metabolism by fluconazole in vitro and in patients with acute promyelocytic leukemia. ( Gallagher, RE; Hallam, S; Schwartz, EL; Wiernik, PH, 1995)
" Here, we discuss about the diagnosis and treatment process of the IIH emerging in a young acute promyelocytic leukemia (APL) case with the ATRA impact, which can be increased by posaconazole."4.12Papilledema and idiopathic intracranial hypertension due to the possible potentiation of ATRA by posaconazole in a case of acute promyelocytic leukemia. ( Atas, U; Aydin Ersoy, M; Iltar, U; Salim, O; Turkoglu, EB; Yucel, OK, 2022)
"We describe 2 patients with acute promyelocytic leukemia (APL) in whom torsade de pointes (TdP) developed during treatment with arsenic trioxide."3.73Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy. ( Kobayashi, M; Naito, K; Nakamura, S; Ohnishi, K; Ohno, R; Sahara, N; Shigeno, K; Shinjo, K; Takeshita, A; Tobita, T, 2006)
" One patient had developed a chronic systemic candidiasis during consolidation chemotherapy and received prophylactic oral or iv fluconazole (200 mg daily) throughout BMT."3.69Successful bone marrow transplantation in patients with previous invasive fungal infections: report of four cases. ( Altés, A; Brunet, S; Domingo-Albós, A; Martínez, C; Martino, R; Nomdedéu, J; Sureda, A, 1994)
"The patient was diagnosed as having acute promyelocytic leukemia microgranular type (M3v) and was therefore administered all-trans retinoic acid (ATRA)."1.35[Hypercalcemia associated with all-trans retinoic acid therapy for microgranular type acute promyelocytic leukemia]. ( Hisatake, J; Shimozuma, J, 2008)
"All-trans-retinoic acid induces acute promyelocytic leukemia cell differentiation in vitro, and it produces greater than 90% complete remissions in patients with acute promyelocytic leukemia."1.29Inhibition of all-trans-retinoic acid metabolism by fluconazole in vitro and in patients with acute promyelocytic leukemia. ( Gallagher, RE; Hallam, S; Schwartz, EL; Wiernik, PH, 1995)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's6 (60.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Atas, U1
Aydin Ersoy, M1
Iltar, U1
Yucel, OK1
Turkoglu, EB1
Salim, O1
Hisatake, J1
Shimozuma, J1
Vanier, KL1
Mattiussi, AJ1
Johnston, DL1
Allione, A1
Montanaro, M1
Marmont, F1
Pomero, F1
Porta, M1
Naito, K1
Kobayashi, M1
Sahara, N1
Shigeno, K1
Nakamura, S1
Shinjo, K1
Tobita, T1
Takeshita, A1
Ohno, R1
Ohnishi, K1
Yarali, N1
Tavil, B1
Kara, A1
Ozkasap, S1
Tunç, B1
Schwartz, EL1
Hallam, S1
Gallagher, RE1
Wiernik, PH1
Seki, H1
Seno, A1
Sakazume, S1
Shinoda, K1
Shintani, N1
Wada, T1
Wada, H1
Koizumi, S1
Taniguchi, N1
Horita, S1
Martino, R1
Nomdedéu, J1
Altés, A1
Sureda, A1
Brunet, S1
Martínez, C1
Domingo-Albós, A1
Smith, KJ1
Welsh, M1
Skelton, H1

Trials

1 trial available for fluconazole and Leukemia, Promyelocytic, Acute

ArticleYear
[Clinical study of fluconazole-injectable and -granules in pediatric patients].
    The Japanese journal of antibiotics, 1994, Volume: 47, Issue:3

    Topics: Administration, Oral; Anemia, Aplastic; Aspergillosis; Candidiasis; Fluconazole; Humans; Injections,

1994

Other Studies

9 other studies available for fluconazole and Leukemia, Promyelocytic, Acute

ArticleYear
Papilledema and idiopathic intracranial hypertension due to the possible potentiation of ATRA by posaconazole in a case of acute promyelocytic leukemia.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:6

    Topics: Adult; Fluconazole; Humans; Leukemia, Promyelocytic, Acute; Male; Papilledema; Pseudotumor Cerebri;

2022
[Hypercalcemia associated with all-trans retinoic acid therapy for microgranular type acute promyelocytic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:6

    Topics: Adult; Antineoplastic Agents; Drug Interactions; Drug Therapy, Combination; Fluconazole; Humans; Hyp

2008
Interaction of all-trans-retinoic acid with fluconazole in acute promyelocytic leukemia.
    Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Cytochrome P-450 Enzyme System; Drug Interactions; Femal

2003
Fungal endophthalmitis in acute leukaemia.
    British journal of haematology, 2004, Volume: 124, Issue:3

    Topics: Acute Disease; Adult; Antifungal Agents; Endophthalmitis; Eye Infections, Fungal; Fluconazole; Human

2004
Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy.
    International journal of hematology, 2006, Volume: 83, Issue:4

    Topics: Adult; Anthracyclines; Antifungal Agents; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cardi

2006
Acute renal failure during ATRA treatment.
    Pediatric hematology and oncology, 2008, Volume: 25, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Antifungal Agents; Antineoplastic Agents; Female; Fluconazole; Huma

2008
Inhibition of all-trans-retinoic acid metabolism by fluconazole in vitro and in patients with acute promyelocytic leukemia.
    Biochemical pharmacology, 1995, Sep-28, Volume: 50, Issue:7

    Topics: Adult; Antifungal Agents; Drug Interactions; Female; Fluconazole; Humans; In Vitro Techniques; Leuke

1995
Successful bone marrow transplantation in patients with previous invasive fungal infections: report of four cases.
    Bone marrow transplantation, 1994, Volume: 13, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Amphotericin B; Aspergillosis; Aspergillus; Bone Marrow Tra

1994
Trichophyton rubrum showing deep dermal invasion directly from the epidermis in immunosuppressed patients.
    The British journal of dermatology, 2001, Volume: 145, Issue:2

    Topics: Adolescent; Adult; Amphotericin B; Anti-Inflammatory Agents; Antifungal Agents; Antineoplastic Combi

2001