fluconazole has been researched along with Leukemia, Myeloid in 12 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Leukemia, Myeloid: Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Invasive fungal infections have increasingly become a matter of concern with regard to patients receiving intensive myelosuppressive therapy for hematologic malignancies." | 2.69 | Failure of fluconazole prophylaxis to reduce mortality or the requirement of systemic amphotericin B therapy during treatment for refractory acute myeloid leukemia: results of a prospective randomized phase III study. German AML Cooperative Group. ( Behre, G; Büchner, T; Eimermacher, H; Grote-Metke, A; Hiddemann, W; Kerkhoff, A; Kern, W; Kubica, U; Rudolf, T; Wörmann, B, 1998) |
| "Posaconazole has shown superior clinical efficacy in the prevention of invasive fungal disease (IFD) among neutropenic patients as well as cost-effectiveness in the US healthcare setting vs fluconazole or itraconazole (FLU/ITRA) based on oral suspension formulations of each therapy." | 1.42 | An update to the cost-effectiveness of posaconazole vs fluconazole or itraconazole in the prevention of invasive fungal disease among neutropenic patients in the United States. ( Marcella, SW; Sung, AH; Xie, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sung, AH | 1 |
| Marcella, SW | 1 |
| Xie, Y | 1 |
| Pereira, GH | 1 |
| Pádua, SS | 1 |
| Park, MV | 1 |
| Muller, RP | 1 |
| Passos, RM | 1 |
| Menezes, Y | 1 |
| Hara, S | 1 |
| Yokote, T | 1 |
| Oka, S | 1 |
| Akioka, T | 1 |
| Kobayashi, K | 1 |
| Hirata, Y | 1 |
| Miyoshi, T | 1 |
| Tsuji, M | 1 |
| Hanafusa, T | 1 |
| Stark, A | 1 |
| Dale, B | 1 |
| Toolis, F | 1 |
| Huijgens, PC | 1 |
| van Loenen, AC | 1 |
| Simoons-Smit, AM | 1 |
| Prooy, E | 1 |
| Ossenkoppele, GJ | 1 |
| Epstein, JB | 1 |
| Ransier, A | 1 |
| Lunn, R | 1 |
| Chin, E | 1 |
| Jacobson, JJ | 1 |
| Le, N | 1 |
| Reece, D | 1 |
| Horowitz, HW | 1 |
| Holmgren, D | 1 |
| Seiter, K | 1 |
| Kern, W | 1 |
| Behre, G | 1 |
| Rudolf, T | 1 |
| Kerkhoff, A | 1 |
| Grote-Metke, A | 1 |
| Eimermacher, H | 1 |
| Kubica, U | 1 |
| Wörmann, B | 1 |
| Büchner, T | 1 |
| Hiddemann, W | 1 |
| Gunsilius, E | 1 |
| Lass-Flörl, C | 1 |
| Kähler, CM | 1 |
| Gastl, G | 1 |
| Petzer, AL | 1 |
| Bruserud, O | 1 |
| McKelvie, PA | 1 |
| Wong, EY | 1 |
| Chow, LP | 1 |
| Hall, AJ | 1 |
| Bignardi, GE | 1 |
| Savage, MA | 1 |
| Coker, R | 1 |
| Davis, SG | 1 |
2 trials available for fluconazole and Leukemia, Myeloid
| Article | Year |
|---|---|
Stepdown single agent antibiotic therapy for the management of the high risk neutropenic adult with hematologic malignancies.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciproflo | 1996 |
Failure of fluconazole prophylaxis to reduce mortality or the requirement of systemic amphotericin B therapy during treatment for refractory acute myeloid leukemia: results of a prospective randomized phase III study. German AML Cooperative Group.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Amphotericin B; Antibiotic Prophylaxis | 1998 |
10 other studies available for fluconazole and Leukemia, Myeloid
| Article | Year |
|---|---|
An update to the cost-effectiveness of posaconazole vs fluconazole or itraconazole in the prevention of invasive fungal disease among neutropenic patients in the United States.
Topics: Antifungal Agents; Cost-Benefit Analysis; Fluconazole; Humans; Itraconazole; Leukemia, Myeloid; Myco | 2015 |
Chronic meningitis by histoplasmosis: report of a child with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Amphotericin B; Antifungal Agents; Chronic Disease; Deoxycholic Acid; Dru | 2008 |
Endophthalmitis due to Trichosporon beigelii in acute leukemia.
Topics: Acute Disease; Adult; Amphotericin B; Antifungal Agents; Drug Resistance, Fungal; Endophthalmitis; F | 2007 |
Fluconazole chemoprophylaxis in neutropenic patients.
Topics: Adult; Candidiasis, Oral; Drug Resistance, Microbial; Female; Fluconazole; Humans; Leukemia, Myeloid | 1993 |
The prophylactic use of fluconazole 50 vs. 100 mg daily in haematological malignancies.
Topics: Adolescent; Adult; Aged; Candidiasis, Oral; Female; Fluconazole; Humans; Leukemia, Myeloid; Lymphoma | 1993 |
Prophylaxis of candidiasis in patients with leukemia and bone marrow transplants.
Topics: Adolescent; Adult; Aged; Antifungal Agents; Bone Marrow Transplantation; Candidiasis, Oral; Dental C | 1996 |
Candida ciferrii, a new fluconazole-resistant yeast causing systemic mycosis in immunocompromised patients.
Topics: Antifungal Agents; Candida; Candidiasis; Drug Resistance, Microbial; Fatal Outcome; Fluconazole; Hum | 2001 |
Effects of azoles on human acute myelogenous leukemia blasts and T lymphocytes derived from acute leukemia patients with chemotherapy-induced cytopenia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antifungal Agents; CD4-Positive T-Lymphocytes; CD8-Positive | 2001 |
Scedosporium endophthalmitis: two fatal disseminated cases of Scedosporium infection presenting with endophthalmitis.
Topics: Acute Disease; Adult; Amphotericin B; Antifungal Agents; Endophthalmitis; Eye Infections, Fungal; Fa | 2001 |
Fluconazole and Candida krusei infections.
Topics: Acute Disease; Candidiasis; Drug Resistance, Microbial; Female; Fluconazole; Fungemia; Humans; Leuke | 1991 |