Page last updated: 2024-10-27

fluconazole and Leishmaniasis

fluconazole has been researched along with Leishmaniasis in 6 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Leishmaniasis: A disease caused by any of a number of species of protozoa in the genus LEISHMANIA. There are four major clinical types of this infection: cutaneous (Old and New World) (LEISHMANIASIS, CUTANEOUS), diffuse cutaneous (LEISHMANIASIS, DIFFUSE CUTANEOUS), mucocutaneous (LEISHMANIASIS, MUCOCUTANEOUS), and visceral (LEISHMANIASIS, VISCERAL).

Research Excerpts

ExcerptRelevanceReference
"Current drug regimens for cutaneous leishmaniasis (CL) include toxic systemic therapies such as amphotericin B (AB) and pentavalent antimonials."3.91Susceptibility testing of Leishmania spp. against amphotericin B and fluconazole using the Sensititre™ YeastOne™ YO9 platform. ( Boggild, AK; Challa, P; Kariyawasam, R; Lau, R, 2019)
"Oral fluconazole has been shown to be more effective than placebo in one instance: for Leishmania major cutaneous disease from Saudi Arabia."2.43Clinical status of agents being developed for leishmaniasis. ( Berman, J, 2005)
"Fluconazole treatment for 6 weeks speeds up the already-rapid cure rate of cutaneous disease due to Leishmania major."2.42Current treatment approaches to leishmaniasis. ( Berman, J, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ortalli, M1
Varani, S1
Rosso, C1
Quintavalla, A1
Lombardo, M1
Trombini, C1
Braga, SS1
Kariyawasam, R1
Challa, P1
Lau, R1
Boggild, AK1
Berman, J2
Iyer, SR1
Iyer, RR1

Reviews

3 reviews available for fluconazole and Leishmaniasis

ArticleYear
Multi-target drugs active against leishmaniasis: A paradigm of drug repurposing.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Amphotericin B; Antifungal Agents; Drug Repositioning; Drug Resistance, Fungal; Fluconazole; Humans;

2019
Current treatment approaches to leishmaniasis.
    Current opinion in infectious diseases, 2003, Volume: 16, Issue:5

    Topics: Amphotericin B; Antimony Sodium Gluconate; Antiprotozoal Agents; Clinical Trials as Topic; Fluconazo

2003
Clinical status of agents being developed for leishmaniasis.
    Expert opinion on investigational drugs, 2005, Volume: 14, Issue:11

    Topics: Aminoquinolines; Antiprotozoal Agents; Fluconazole; Humans; Imiquimod; Ketoconazole; Leishmaniasis;

2005

Other Studies

3 other studies available for fluconazole and Leishmaniasis

ArticleYear
Evaluation of synthetic substituted 1,2-dioxanes as novel agents against human leishmaniasis.
    European journal of medicinal chemistry, 2019, May-15, Volume: 170

    Topics: Animals; Chlorocebus aethiops; Dioxanes; Drug Design; Humans; Leishmania; Leishmaniasis; Parasitic S

2019
Susceptibility testing of Leishmania spp. against amphotericin B and fluconazole using the Sensititre™ YeastOne™ YO9 platform.
    BMC infectious diseases, 2019, Jul-08, Volume: 19, Issue:1

    Topics: Amphotericin B; Fluconazole; Humans; Leishmania; Leishmaniasis; Microbial Sensitivity Tests; Parasit

2019
Anti leishmanial therapy--the changing scene.
    The Journal of the Association of Physicians of India, 1995, Volume: 43, Issue:3

    Topics: Antifungal Agents; Fluconazole; Humans; Ketoconazole; Leishmaniasis

1995