fluconazole has been researched along with Leishmaniasis, American in 37 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Oral fluconazole at a dosage of 6." | 2.84 | Fluconazole in the Treatment of Cutaneous Leishmaniasis Caused by Leishmania braziliensis: A Randomized Controlled Trial. ( Almeida, J; Brito, MD; Carvalho, EM; Dourado, ME; Guimarães, LH; Machado, PR; Prates, FV; Schriefer, A; Silva, SC, 2017) |
| "Fluconazole was well tolerated." | 2.76 | High-dose oral fluconazole therapy effective for cutaneous leishmaniasis due to Leishmania (Vianna) braziliensis. ( Frutuoso, MS; Moraes, EA; Pearson, RD; Pompeu, MM; Sousa, AQ, 2011) |
| "Cutaneous leishmaniasis was not considered as an initial diagnosis because of the atypical appearance of the lesion as well as his residence in the hilly region of Nepal." | 1.62 | Case Report: An Atypical Erysipeloid Presentation of Cutaneous Leishmaniasis from the Hilly Region of Nepal. ( Nepal, S, 2021) |
| "Treatment with meglumine antimoniate (Glucantime) was ineffective." | 1.56 | [Cutaneous leishmaniasis of the vermilion border of the upper lip extending to the oral mucosa]. ( Boumezzourh, A; Chiheb, S; Dessay, M; Elfatoiki, FZ; Elkhalfaoui, N; Maksouri, H; Riyad, M, 2020) |
| "Cutaneous leishmaniasis has an incidence of 0." | 1.48 | Pediatric Old World cutaneous leishmaniasis treated with oral fluconazole: A case series. ( Barruscotti, S; Bossi, G; Brazzelli, V; Michelerio, A, 2018) |
| "Oral fluconazole was started and the lesion resolved completely." | 1.42 | Cutaneous leishmaniasis mimicking granulomatous cheilitis and treated successfully with oral fluconazole in a boy. ( Aksakal, M; Serarslan, G, 2015) |
| "American cutaneous leishmaniasis is an endemic anthropozoonosis that exhibits a broad spectrum of clinical presentations." | 1.40 | Intermediate cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis successfully treated with fluconazole. ( Convit, J; Daly, K; De Lima, H; Kato, H; Paniz-Mondolfi, AE; Reyes-Jaimes, O; Sordillo, EM; Zerpa, O, 2014) |
| "The optimal treatment of cutaneous leishmaniasis is controversial." | 1.36 | Management of old world cutaneous leishmaniasis in refugee children. ( Crogan, J; Gunasekera, H; Isaacs, D; Sheikh, M; Wood, N, 2010) |
| " A pharmacokinetic study was conducted on Days 1 and 14 of treatment, representing single- and multiple-dose pharmacokinetics, respectively." | 1.34 | Effects of fluconazole on the pharmacokinetics and pharmacodynamics of antimony in cutaneous leishmaniasis-infected hamsters. ( Abou Alsoud, N; Al-Jaser, M; Alnaim, L; Zaghloul, I, 2007) |
| "Oral fluconazole treatment resulted in complete resolution." | 1.33 | Oral fluconazole treatment for extensive cutaneous leishmaniasis in an 11-year-old child. ( Armengaud, JB; Dupouy Camet, J; Gendrel, D; Toubiana, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.70) | 18.2507 |
| 2000's | 10 (27.03) | 29.6817 |
| 2010's | 20 (54.05) | 24.3611 |
| 2020's | 6 (16.22) | 2.80 |
| Authors | Studies |
|---|---|
| Hill, N | 1 |
| Irwin, A | 1 |
| Graham, N | 1 |
| Leung, C | 1 |
| Francis, JR | 1 |
| Wall, N | 1 |
| Nourse, C | 1 |
| Mitra, D | 1 |
| Bhatnagar, A | 1 |
| Patil, C | 1 |
| Kothari, R | 1 |
| Yadav, N | 1 |
| Madke, B | 1 |
| Elfatoiki, FZ | 1 |
| Boumezzourh, A | 1 |
| Maksouri, H | 1 |
| Elkhalfaoui, N | 1 |
| Dessay, M | 1 |
| Riyad, M | 1 |
| Chiheb, S | 1 |
| Nepal, S | 1 |
| Veraldi, S | 2 |
| Romagnuolo, M | 1 |
| Cusini, M | 1 |
| Maronese, CA | 1 |
| Laurent, K | 1 |
| Susong, J | 1 |
| Fillman, E | 1 |
| Ritchie, S | 1 |
| Elmehdi, E | 1 |
| Zerkly, B | 1 |
| Francesconi, VA | 1 |
| Francesconi, F | 1 |
| Ramasawmy, R | 1 |
| Romero, GAS | 1 |
| Alecrim, MDGC | 1 |
| Michelerio, A | 1 |
| Barruscotti, S | 1 |
| Bossi, G | 1 |
| Brazzelli, V | 1 |
| Benzaquen, M | 1 |
| Chambelland, A | 1 |
| Fongue, J | 1 |
| Melenotte, C | 1 |
| Christen, JR | 1 |
| Ranque, S | 1 |
| Buono, JP | 1 |
| Parola, P | 1 |
| Berbis, P | 1 |
| Hegg, RM | 1 |
| Alkousakis, TJ | 1 |
| Swick, BL | 1 |
| Daly, K | 1 |
| De Lima, H | 1 |
| Kato, H | 1 |
| Sordillo, EM | 1 |
| Convit, J | 1 |
| Reyes-Jaimes, O | 1 |
| Zerpa, O | 1 |
| Paniz-Mondolfi, AE | 1 |
| Oliveira, MB | 1 |
| Calixto, G | 1 |
| Graminha, M | 1 |
| Cerecetto, H | 1 |
| González, M | 1 |
| Chorilli, M | 1 |
| Nazzaro, G | 1 |
| Serarslan, G | 1 |
| Aksakal, M | 1 |
| Sousa, AQ | 2 |
| Lima Pompeu, MM | 1 |
| Pearson, RD | 2 |
| Ouadi, Z | 1 |
| Akhdari, N | 1 |
| Hocar, O | 1 |
| Amal, S | 1 |
| Tassi, N | 1 |
| Chacko, A | 1 |
| Joseph, M | 1 |
| Feltis, T | 1 |
| Morris, SK | 1 |
| Prates, FV | 1 |
| Dourado, ME | 1 |
| Silva, SC | 1 |
| Schriefer, A | 1 |
| Guimarães, LH | 1 |
| Brito, MD | 1 |
| Almeida, J | 1 |
| Carvalho, EM | 1 |
| Machado, PR | 1 |
| Caridha, D | 1 |
| Parriot, S | 1 |
| Hudson, TH | 1 |
| Lang, T | 1 |
| Ngundam, F | 1 |
| Leed, S | 1 |
| Sena, J | 1 |
| Harris, M | 1 |
| O'Neil, M | 1 |
| Sciotti, R | 1 |
| Read, L | 1 |
| Lecoeur, H | 1 |
| Hickman, M | 1 |
| Grogl, M | 2 |
| Crogan, J | 1 |
| Gunasekera, H | 1 |
| Wood, N | 1 |
| Sheikh, M | 1 |
| Isaacs, D | 1 |
| Fathy, FM | 1 |
| El-Kasah, F | 1 |
| El-Ahwal, AM | 1 |
| Sklavos, AV | 1 |
| Walls, T | 1 |
| Webber, MT | 1 |
| Watson, AB | 1 |
| Emad, M | 1 |
| Hayati, F | 1 |
| Fallahzadeh, MK | 1 |
| Namazi, MR | 1 |
| Frutuoso, MS | 1 |
| Moraes, EA | 1 |
| Pompeu, MM | 1 |
| Torres, JR | 1 |
| Suárez, JA | 1 |
| Zvulunov, A | 1 |
| Klaus, S | 1 |
| Vardy, D | 1 |
| Baron, S | 1 |
| Laube, S | 1 |
| Raafat, F | 1 |
| Moss, C | 1 |
| Laffitte, E | 2 |
| Genton, B | 1 |
| Panizzon, RG | 1 |
| Quante, G | 1 |
| Wittekindt, C | 1 |
| Beutner, D | 1 |
| Preuss, SF | 1 |
| Damm, M | 1 |
| Hüttenbrink, KB | 1 |
| Toubiana, J | 1 |
| Armengaud, JB | 1 |
| Dupouy Camet, J | 1 |
| Gendrel, D | 1 |
| Mussi, SV | 1 |
| Fernandes, AP | 1 |
| Ferreira, LA | 1 |
| Morizot, G | 1 |
| Delgiudice, P | 1 |
| Caumes, E | 1 |
| Marty, P | 1 |
| Dupuy, A | 1 |
| Sarfati, C | 1 |
| Hadj-Rabia, S | 1 |
| Darie, H | 1 |
| LE Guern, AS | 1 |
| Salah, AB | 1 |
| Pratlong, F | 1 |
| Dedet, JP | 1 |
| Buffet, PA | 1 |
| Alnaim, L | 1 |
| Abou Alsoud, N | 1 |
| Zaghloul, I | 1 |
| Al-Jaser, M | 1 |
| Al-Abdely, HM | 1 |
| Graybill, JR | 1 |
| Loebenberg, D | 1 |
| Melby, PC | 1 |
| Alrajhi, AA | 1 |
| Ibrahim, EA | 1 |
| De Vol, EB | 1 |
| Khairat, M | 1 |
| Faris, RM | 1 |
| Maguire, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 3 Randomized Trial Comparing Fluconazole to Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis Caused by L. Braziliensis and L. Guyanensis[NCT01953744] | Phase 3 | 53 participants (Actual) | Interventional | 2014-02-28 | Terminated (stopped due to Low cure rate in the study (fluconazole) group) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for fluconazole and Leishmaniasis, American
| Article | Year |
|---|---|
Failure of fluconazole in treating cutaneous leishmaniasis caused by Leishmania guyanensis in the Brazilian Amazon: An open, nonrandomized phase 2 trial.
Topics: Administration, Oral; Adolescent; Adult; Antiprotozoal Agents; Brazil; Fluconazole; Hand; Humans; Le | 2018 |
Fluconazole in the Treatment of Cutaneous Leishmaniasis Caused by Leishmania braziliensis: A Randomized Controlled Trial.
Topics: Adolescent; Adult; Antimony; Antiprotozoal Agents; Brazil; Female; Fluconazole; Humans; Leishmania b | 2017 |
Superior efficacy of oral fluconazole 400 mg daily versus oral fluconazole 200 mg daily in the treatment of cutaneous leishmania major infection: a randomized clinical trial.
Topics: Adult; Female; Fluconazole; Humans; Leishmania major; Leishmaniasis, Cutaneous; Male; Middle Aged | 2011 |
High-dose oral fluconazole therapy effective for cutaneous leishmaniasis due to Leishmania (Vianna) braziliensis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiprotozoal Agents; Child; Child, Preschool; Female; F | 2011 |
Healing of Old World cutaneous leishmaniasis in travelers treated with fluconazole: drug effect or spontaneous evolution?
Topics: Adult; Aged; Aged, 80 and over; Animals; Antiparasitic Agents; Biological Evolution; Child; Child, P | 2007 |
Fluconazole for the treatment of cutaneous leishmaniasis caused by Leishmania major.
Topics: Adult; Animals; Antifungal Agents; Double-Blind Method; Endemic Diseases; Female; Fluconazole; Follo | 2002 |
31 other studies available for fluconazole and Leishmaniasis, American
| Article | Year |
|---|---|
Treatment of Cutaneous Leishmaniasis in a Nonendemic Country: A Case Series of Children in Australia.
Topics: Administration, Topical; Antiprotozoal Agents; Child; Fluconazole; Humans; Leishmaniasis, Cutaneous; | 2022 |
Successful management of pediatric cases of cutaneous leishmaniasis with oral fluconazole.
Topics: Administration, Oral; Antifungal Agents; Antiprotozoal Agents; Child; Fluconazole; Humans; Leishmani | 2023 |
Case Report: Diffuse Cutaneous Leishmaniasis Successfully Treated with a Combination of Oral Rifampicin and Fluconazole.
Topics: Female; Fluconazole; Humans; Leishmania; Leishmaniasis, Cutaneous; Leishmaniasis, Diffuse Cutaneous; | 2023 |
[Cutaneous leishmaniasis of the vermilion border of the upper lip extending to the oral mucosa].
Topics: Adolescent; Facial Dermatoses; Female; Fluconazole; Humans; Leishmaniasis, Cutaneous; Lip; Lip Disea | 2020 |
Case Report: An Atypical Erysipeloid Presentation of Cutaneous Leishmaniasis from the Hilly Region of Nepal.
Topics: Antifungal Agents; Antiprotozoal Agents; Fluconazole; Humans; Leishmaniasis, Cutaneous; Male; Middle | 2021 |
Therapy of cutaneous leishmaniasis caused by Leishmania braziliensis with fluconazole.
Topics: Fluconazole; Humans; Leishmania braziliensis; Leishmaniasis, Cutaneous | 2021 |
Cutaneous Leishmaniasis in a Saudi Arabian Soldier Stationed in the United States.
Topics: Adult; Emergency Service, Hospital; Fluconazole; Humans; Leishmaniasis, Cutaneous; Male; Military Pe | 2017 |
[Leg ulcer revealing cutaneous leishmaniasis].
Topics: Administration, Topical; Adolescent; Animals; Antiparasitic Agents; Biopsy; Fluconazole; Humans; Leg | 2017 |
Pediatric Old World cutaneous leishmaniasis treated with oral fluconazole: A case series.
Topics: Administration, Oral; Antifungal Agents; Child; Child, Preschool; Female; Fluconazole; Humans; Leish | 2018 |
Cutaneous sporotrichoid leishmaniasis treated with oral fluconazole.
Topics: Administration, Oral; Aged; Antifungal Agents; Fluconazole; Humans; Leishmania; Leishmaniasis, Cutan | 2019 |
What is your diagnosis? Old world Leishmaniasis.
Topics: Aminoquinolines; Anti-Infective Agents; Arm; Cryotherapy; Fluconazole; Humans; Imiquimod; Iraq; Leis | 2014 |
Intermediate cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis successfully treated with fluconazole.
Topics: Antifungal Agents; Child; Female; Fluconazole; Humans; Leishmania braziliensis; Leishmaniasis, Cutan | 2014 |
Development, characterization, and in vitro biological performance of fluconazole-loaded microemulsions for the topical treatment of cutaneous leishmaniasis.
Topics: Adhesiveness; Administration, Topical; Animals; Cell Line; Emulsions; Female; Fluconazole; Hardness; | 2015 |
Successful treatment of cutaneous leishmaniasis of the ear with oral fluconazole.
Topics: Administration, Oral; Antifungal Agents; Ear Diseases; Fluconazole; Humans; Leishmaniasis, Cutaneous | 2016 |
Cutaneous leishmaniasis mimicking granulomatous cheilitis and treated successfully with oral fluconazole in a boy.
Topics: Antiprotozoal Agents; Child; Diagnosis, Differential; Fluconazole; Humans; Leishmaniasis, Cutaneous; | 2015 |
Disseminated Cutaneous Leishmaniasis, a Patient with 178 Lesions Cured with Fluconazole.
Topics: Antifungal Agents; Fluconazole; Humans; Leishmaniasis, Cutaneous; Male; Middle Aged; Treatment Outco | 2016 |
[Polymorphic lesions of cutaneous leishmaniasis revealing human immunodeficiency virus infection].
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiprotozoal Agents; Antiretroviral Therapy | 2016 |
Successful Treatment of Cutaneous Leishmaniasis with Topical Paramomycin in a Child After Treatment Failure with Systemic Fluconazole.
Topics: Administration, Oral; Administration, Topical; Antiprotozoal Agents; Child, Preschool; Fluconazole; | 2016 |
Use of Optical Imaging Technology in the Validation of a New, Rapid, Cost-Effective Drug Screen as Part of a Tiered
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Drug Evaluation, Preclinica | 2017 |
Management of old world cutaneous leishmaniasis in refugee children.
Topics: Amphotericin B; Animals; Antifungal Agents; Australia; Child; Female; Fluconazole; Humans; Infant; L | 2010 |
Emerging cutaneous leishmaniasis in Sirte-Libya: epidemiology, recognition and management.
Topics: Adolescent; Adult; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Cryotherapy; Dis | 2009 |
Cutaneous leishmaniasis in a child treated with oral fluconazole.
Topics: Administration, Oral; Cephalexin; Child, Preschool; Cicatrix; Female; Fluconazole; Humans; Leishmani | 2010 |
Fluconazole effectiveness against Leishmania (Viannia) braziliensis: is the evidence enough?
Topics: Antiprotozoal Agents; Female; Fluconazole; Humans; Leishmania braziliensis; Leishmaniasis, Cutaneous | 2012 |
Fluconazole for the treatment of cutaneous leishmaniasis.
Topics: Administration, Topical; Animals; Antifungal Agents; Antiprotozoal Agents; Fluconazole; Humans; Leis | 2002 |
Cutaneous leishmaniasis in a Kosovan child treated with oral fluconazole.
Topics: Administration, Oral; Antifungal Agents; Child, Preschool; Female; Fluconazole; Humans; Leishmaniasi | 2004 |
Cutaneous leishmaniasis caused by Leishmania tropica: treatment with oral fluconazole.
Topics: Administration, Oral; Adult; Animals; Antifungal Agents; Diagnosis, Differential; Female; Fluconazol | 2005 |
[Chronic-persistent infection of the auricle].
Topics: Animals; Antifungal Agents; Chronic Disease; Ear, External; Fluconazole; Humans; Leishmania tropica; | 2006 |
Oral fluconazole treatment for extensive cutaneous leishmaniasis in an 11-year-old child.
Topics: Administration, Oral; Animals; Antifungal Agents; Child; Female; Fluconazole; Humans; Leishmania maj | 2006 |
Comparative study of the efficacy of formulations containing fluconazole or paromomycin for topical treatment of infections by Leishmania (Leishmania) major and Leishmania (Leishmania) amazonensis.
Topics: Administration, Oral; Administration, Topical; Animals; Antiprotozoal Agents; Dose-Response Relation | 2007 |
Effects of fluconazole on the pharmacokinetics and pharmacodynamics of antimony in cutaneous leishmaniasis-infected hamsters.
Topics: Administration, Oral; Animals; Antifungal Agents; Antimony; Antiprotozoal Agents; Area Under Curve; | 2007 |
Efficacy of the triazole SCH 56592 against Leishmania amazonensis and Leishmania donovani in experimental murine cutaneous and visceral leishmaniases.
Topics: Amphotericin B; Animals; Fluconazole; Leishmania donovani; Leishmaniasis, Cutaneous; Leishmaniasis, | 1999 |