fluconazole has been researched along with Kidney Failure in 23 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Whether echinocandins could be used to treat candidemia of a urinary tract source (CUTS) is unknown." | 5.46 | Echinocandins Compared to Fluconazole for Candidemia of a Urinary Tract Source: A Propensity Score Analysis. ( Aguado, JM; Almirante, B; Ayats, J; Blanco-Vidal, MJ; Cardozo, C; Carratalà, J; Cuervo, G; Fernández-Ruiz, M; Garcia-Vidal, C; González-Barberá, E; Gudiol, C; Manzur, A; Marco, F; Meije, Y; Montejo, JM; Muñoz, P; Pemán, J; Puig-Asensio, M; Vena, A, 2017) |
| "Amphotericin B was significantly more toxic than Fluconazole especially in related allogeneic transplantation where 19% of patients developed toxicity vs 0% of Fluconazole recipients (p < 0." | 2.69 | Fluconazole vs low-dose amphotericin B for the prevention of fungal infections in patients undergoing bone marrow transplantation: a study of the North American Marrow Transplant Group. ( Bolwell, B; Collins, R; Dummer, S; Ericson, S; Fay, J; Freytes, CO; Goodman, SA; Greer, J; Herzig, RH; LeMaistre, F; Lynch, J; Pineiro, L; Pohlman, B; Stein, R; Stevens, D; Wolff, SN, 2000) |
| "Fluconazole (FLU) is a widely used antifungal agent." | 2.68 | Pharmacokinetics of fluconazole in renal failure. ( Baris, BA; Berl, T; Farmer, B; Gardner, M; Hansen, RA; Henrich, WL; Wilner, KD, 1995) |
| "Eight patients had symptomatic recurrence of lesions 3-12 weeks after treatment and underwent reoperation." | 2.52 | Intracranial Fungal Granulomas: A Single Institutional Clinicopathologic Study of 66 Patients and Review of the Literature. ( Ahmed, FU; Garg, A; Gupta, A; Mahapatra, AK; Naik, V; Sarkar, C; Sharma, B, 2015) |
| "Identification of infected cysts should be pursued in such cases, particularly with PET-CT, and when technically possible followed by cyst aspiration and culture to guide treatment." | 1.51 | Two cases of fungal cyst infection in ADPKD: is this really a rare complication? ( Balbo, BEP; Chocair, PR; de Abreu Testagrossa, L; de Almeida, MCS; de Menezes Neves, PDM; Ferreira, FT; Onuchic, L; Onuchic, LF; Portela-Neto, AA; Sato, VAH; Watanabe, A; Watanabe, EH, 2019) |
| "Whether echinocandins could be used to treat candidemia of a urinary tract source (CUTS) is unknown." | 1.46 | Echinocandins Compared to Fluconazole for Candidemia of a Urinary Tract Source: A Propensity Score Analysis. ( Aguado, JM; Almirante, B; Ayats, J; Blanco-Vidal, MJ; Cardozo, C; Carratalà, J; Cuervo, G; Fernández-Ruiz, M; Garcia-Vidal, C; González-Barberá, E; Gudiol, C; Manzur, A; Marco, F; Meije, Y; Montejo, JM; Muñoz, P; Pemán, J; Puig-Asensio, M; Vena, A, 2017) |
| "Given that drug dosing schedules utilise eGFR values as the basis for modifying drug dosing, our results would suggest that a recommendation of a dose reduction according to eGFR alone should be treated with caution." | 1.40 | GFR may not accurately predict aspects of proximal tubule drug handling. ( Duffull, SB; Putt, TL; Schollum, JB; Walker, RJ, 2014) |
| "Graft site candidiasis is a rare but life-threatening complication of renal transplant." | 1.39 | Candida arteritis in a pair of renal transplant recipients. ( Ashley, S; Barwell, J; Chinai, N; Cunningham, R; Guy, A; Rowe, P, 2013) |
| "The optimal treatment of cutaneous leishmaniasis is controversial." | 1.36 | Management of old world cutaneous leishmaniasis in refugee children. ( Crogan, J; Gunasekera, H; Isaacs, D; Sheikh, M; Wood, N, 2010) |
| " Accordingly, we made the diagnosis of cryptococcal meningitis and immediately started multiple anti fungal drugs with dosage modification according to her impaired renal function." | 1.34 | [A case of cryptococcal meningitis with nephrotic syndrome and renal insufficiency under immunosuppressive therapy]. ( Ichikawa, D; Kimura, K; Sato, T; Shima, Y; Tsuchida, H; Yasuda, T, 2007) |
| "Standard treatments for visceral leishmaniasis (antimonials, amphotericin B and pentamidine) pose several problems." | 1.33 | Successful treatment of visceral leishmaniasis with fluconazole and allopurinol in a patient with renal failure. ( Colakoglu, M; Colakoglu, NY; Yaylali, GF; Yilmaz, M, 2006) |
| "Standard treatments for visceral leishmaniasis (antimonials, amphotericin B and pentamidine) pose several problems." | 1.33 | Successful treatment of visceral leishmaniasis with fluconazole and allopurinol in a patient with renal failure. ( Colakoglu, M; Fidan Yaylali, G; Yalcin Colakoglu, N; Yilmaz, M, 2006) |
| "Fluconazole was infused for 30 min at intervals of 24 h, with an initial dose of 400 mg and following doses of 200 mg." | 1.30 | Interaction between fluconazole and midazolam in intensive care patients. ( Ahonen, J; Neuvonen, PJ; Olkkola, KT; Takala, A, 1999) |
| "Fluconazole is an effective oral or intravenous anti-fungal agent." | 1.29 | Fluconazole infused via a nephrostomy tube: a novel and effective route of delivery. ( Oliver, SE; Walker, RJ; Woods, DJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 9 (39.13) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Onuchic, L | 1 |
| Sato, VAH | 1 |
| de Menezes Neves, PDM | 1 |
| Balbo, BEP | 1 |
| Portela-Neto, AA | 1 |
| Ferreira, FT | 1 |
| Watanabe, EH | 1 |
| Watanabe, A | 1 |
| de Almeida, MCS | 1 |
| de Abreu Testagrossa, L | 1 |
| Chocair, PR | 1 |
| Onuchic, LF | 1 |
| Cuervo, G | 1 |
| Garcia-Vidal, C | 1 |
| Puig-Asensio, M | 1 |
| Vena, A | 1 |
| Meije, Y | 1 |
| Fernández-Ruiz, M | 1 |
| González-Barberá, E | 1 |
| Blanco-Vidal, MJ | 1 |
| Manzur, A | 1 |
| Cardozo, C | 1 |
| Gudiol, C | 1 |
| Montejo, JM | 1 |
| Pemán, J | 1 |
| Ayats, J | 1 |
| Aguado, JM | 1 |
| Muñoz, P | 1 |
| Marco, F | 1 |
| Almirante, B | 1 |
| Carratalà, J | 1 |
| Dreyfuss, D | 1 |
| Ricard, JD | 1 |
| Gaudry, S | 1 |
| Guy, A | 1 |
| Chinai, N | 1 |
| Ashley, S | 1 |
| Rowe, P | 1 |
| Cunningham, R | 1 |
| Barwell, J | 1 |
| Putt, TL | 1 |
| Duffull, SB | 1 |
| Schollum, JB | 1 |
| Walker, RJ | 2 |
| Naik, V | 1 |
| Ahmed, FU | 1 |
| Gupta, A | 1 |
| Garg, A | 1 |
| Sarkar, C | 1 |
| Sharma, B | 1 |
| Mahapatra, AK | 1 |
| Furman-Kuklińska, K | 1 |
| Naumnik, B | 1 |
| Myśliwiec, M | 1 |
| Crogan, J | 1 |
| Gunasekera, H | 1 |
| Wood, N | 1 |
| Sheikh, M | 1 |
| Isaacs, D | 1 |
| Dubert, M | 1 |
| Loi, V | 1 |
| Tligui, M | 1 |
| Hertig, A | 1 |
| Cousin, L | 1 |
| Berre, ML | 1 |
| Launay-Vacher, V | 1 |
| Izzedine, H | 1 |
| Deray, G | 1 |
| Sabbatani, S | 1 |
| Manfredi, R | 1 |
| Pavoni, M | 1 |
| Consales, A | 1 |
| Chiodo, F | 1 |
| Montravers, P | 1 |
| Jabbour, K | 1 |
| Colakoglu, M | 2 |
| Yaylali, GF | 1 |
| Colakoglu, NY | 1 |
| Yilmaz, M | 2 |
| Fidan Yaylali, G | 1 |
| Yalcin Colakoglu, N | 1 |
| Tsuchida, H | 1 |
| Ichikawa, D | 1 |
| Shima, Y | 1 |
| Yasuda, T | 1 |
| Sato, T | 1 |
| Kimura, K | 1 |
| Berl, T | 1 |
| Wilner, KD | 1 |
| Gardner, M | 1 |
| Hansen, RA | 1 |
| Farmer, B | 1 |
| Baris, BA | 1 |
| Henrich, WL | 1 |
| Xie, W | 1 |
| Li, X | 1 |
| Oliver, SE | 1 |
| Woods, DJ | 1 |
| Maslo, C | 1 |
| Peraldi, MN | 1 |
| Desenclos, JC | 1 |
| Mougenot, B | 1 |
| Cywiner-Golenzer, C | 1 |
| Chatelet, FP | 1 |
| Jacomet, C | 1 |
| Rondeau, E | 1 |
| Rozenbaum, W | 1 |
| Sraer, JD | 1 |
| Díez-Delgado Rubio, J | 1 |
| González-Ripoll Garzón, M | 1 |
| Sánchcz Vázquez, AR | 1 |
| Ortiz López, I | 1 |
| Ahonen, J | 1 |
| Olkkola, KT | 1 |
| Takala, A | 1 |
| Neuvonen, PJ | 1 |
| Wolff, SN | 1 |
| Fay, J | 1 |
| Stevens, D | 1 |
| Herzig, RH | 1 |
| Pohlman, B | 1 |
| Bolwell, B | 1 |
| Lynch, J | 1 |
| Ericson, S | 1 |
| Freytes, CO | 1 |
| LeMaistre, F | 1 |
| Collins, R | 1 |
| Pineiro, L | 1 |
| Greer, J | 1 |
| Stein, R | 1 |
| Goodman, SA | 1 |
| Dummer, S | 1 |
| Ramos, L | 1 |
| López, C | 1 |
| Gómez, C | 1 |
| Mathurín, S | 1 |
| Mateo, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ANTIVORIFUNGOL:Strategy of Antifungal Use in Oncohematological Neutropenic Patients. Use of Voriconazole as Early Treatment.[NCT00386802] | Phase 4 | 115 participants (Anticipated) | Interventional | 2006-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for fluconazole and Kidney Failure
| Article | Year |
|---|---|
Intracranial Fungal Granulomas: A Single Institutional Clinicopathologic Study of 66 Patients and Review of the Literature.
Topics: Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Brain; Central Nervous System Fungal Inf | 2015 |
Dosing guidelines for fluconazole in patients with renal failure.
Topics: Antifungal Agents; Fluconazole; Humans; Renal Insufficiency | 2003 |
Clinical consequences of resistant Candida infections in intensive care.
Topics: Antibiotic Prophylaxis; Antifungal Agents; Candidiasis; Cross Infection; Drug Resistance, Fungal; Fl | 2006 |
2 trials available for fluconazole and Kidney Failure
| Article | Year |
|---|---|
Pharmacokinetics of fluconazole in renal failure.
Topics: Creatinine; Female; Fluconazole; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Renal D | 1995 |
Fluconazole vs low-dose amphotericin B for the prevention of fungal infections in patients undergoing bone marrow transplantation: a study of the North American Marrow Transplant Group.
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Bone Marrow Transplantation; Chemical and Drug Induc | 2000 |
18 other studies available for fluconazole and Kidney Failure
| Article | Year |
|---|---|
Two cases of fungal cyst infection in ADPKD: is this really a rare complication?
Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Candida albicans; Candidiasis; Cysts; Drainage; Fat | 2019 |
Echinocandins Compared to Fluconazole for Candidemia of a Urinary Tract Source: A Propensity Score Analysis.
Topics: Aged; Aged, 80 and over; Antifungal Agents; Candida albicans; Candida glabrata; Candidemia; Cohort S | 2017 |
Amphotericin B deoxycholate for candidiasis in intensive care unit patients revisited: medical, ethical, and financial implications.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Creatinine; Critical Illness; Cross Infection; Deoxy | 2013 |
Candida arteritis in a pair of renal transplant recipients.
Topics: Aged; Antifungal Agents; Arteritis; Candida albicans; Candidiasis; Fluconazole; Humans; Kidney Failu | 2013 |
GFR may not accurately predict aspects of proximal tubule drug handling.
Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Dose-Response Relationship, Drug; Edetic Acid; | 2014 |
Fungaemia due to Cryptococcus laurentii as a complication of immunosuppressive therapy--a case report.
Topics: Adult; Antifungal Agents; Cryptococcosis; Cryptococcus; Fluconazole; Fungemia; Glomerulonephritis, M | 2009 |
Management of old world cutaneous leishmaniasis in refugee children.
Topics: Amphotericin B; Animals; Antifungal Agents; Australia; Child; Female; Fluconazole; Humans; Infant; L | 2010 |
Rapidly progressive kidney failure induced by fungal mycelia obstructing indwelling ureteral stents.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Female; Fluconazole; Humans; Middle Aged; Prosthes | 2012 |
Voriconazole proves effective in long-term treatment of a cerebral cryptococcoma in a chronic nephropathic HIV-negative patient, after fluconazole failure.
Topics: Antifungal Agents; Brain Abscess; Chronic Disease; Cryptococcus neoformans; Fluconazole; HIV Seroneg | 2004 |
Successful treatment of visceral leishmaniasis with fluconazole and allopurinol in a patient with renal failure.
Topics: Allopurinol; Antifungal Agents; Antimetabolites; Diabetic Nephropathies; Fluconazole; Humans; Leishm | 2006 |
Successful treatment of visceral leishmaniasis with fluconazole and allopurinol in a patient with renal failure.
Topics: Allopurinol; Animals; Antimetabolites; Antiprotozoal Agents; Diabetic Nephropathies; Drug Therapy, C | 2006 |
[A case of cryptococcal meningitis with nephrotic syndrome and renal insufficiency under immunosuppressive therapy].
Topics: Aged; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Cyclosporine; Drug Administration | 2007 |
Experience in treating secondary systemic mycotic infection after severe burns associated with electric injury.
Topics: Adult; Amputation, Surgical; Burns, Electric; Candidiasis; Ciprofloxacin; Fluconazole; Humans; Male; | 1995 |
Fluconazole infused via a nephrostomy tube: a novel and effective route of delivery.
Topics: Aged; Antifungal Agents; Candidiasis; Female; Fluconazole; Humans; Nephrostomy, Percutaneous; Renal | 1995 |
Thrombotic microangiopathy and cytomegalovirus disease in patients infected with human immunodeficiency virus.
Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Bronchi; Case-Control Studies; Cyto | 1997 |
[Obstructive renal insufficiency due to Candida. Fluconazole as a valid alternative to classical therapy].
Topics: Antifungal Agents; Candida albicans; Fluconazole; Humans; Infant, Newborn; Male; Renal Insufficiency | 1997 |
Interaction between fluconazole and midazolam in intensive care patients.
Topics: Adult; Analysis of Variance; Antifungal Agents; Critical Care; Cytochrome P-450 CYP3A; Cytochrome P- | 1999 |
Case report. Cutaneous cryptococcosis in a patient with systemic erythematous lupus.
Topics: Adult; Agglutination Tests; Amphotericin B; Antifungal Agents; Antigens, Fungal; Cellulitis; Cryptoc | 2001 |