Page last updated: 2024-10-27

fluconazole and Intestinal Perforation

fluconazole has been researched along with Intestinal Perforation in 7 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Intestinal Perforation: Opening or penetration through the wall of the INTESTINES.

Research Excerpts

ExcerptRelevanceReference
"Rats in Fp groups were given fluconazole in doses of 0 mg/kg, 3 mg/kg, 10 mg/kg, and 30 mg/kg by gavage 30 min before induction of peritonitis."7.72Fluconazole attenuates lung injury and mortality in a rat peritonitis model. ( Arshaduddin, M; Evans, DP; Jacobs, S; Khan, HA; Moutaery, AA; Tariq, M, 2003)
"Fluconazole, 400 mg/day, was given as EPT."5.33Early presumptive therapy with fluconazole for occult Candida infection after gastrointestinal surgery. ( Lee, JC; Lin, PW; Shan, YS; Sy, ED; Wang, ST, 2006)
"Rats in Fp groups were given fluconazole in doses of 0 mg/kg, 3 mg/kg, 10 mg/kg, and 30 mg/kg by gavage 30 min before induction of peritonitis."3.72Fluconazole attenuates lung injury and mortality in a rat peritonitis model. ( Arshaduddin, M; Evans, DP; Jacobs, S; Khan, HA; Moutaery, AA; Tariq, M, 2003)
"Fluconazole, 400 mg/day, was given as EPT."1.33Early presumptive therapy with fluconazole for occult Candida infection after gastrointestinal surgery. ( Lee, JC; Lin, PW; Shan, YS; Sy, ED; Wang, ST, 2006)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liao, X1
Qiu, H1
Li, R1
Guo, F1
Liu, W1
Kang, M1
Kang, Y1
Khoury, W1
Szold, O1
Soffer, D1
Kariv, Y1
Wasserlauf, R1
Klausner, JM1
Ogorek, D1
Weinbroum, AA1
Holzknecht, BJ1
Thorup, J1
Arendrup, MC1
Andersen, SE1
Steensen, M1
Hesselfeldt, P1
Nielsen, JM1
Knudsen, JD1
Alvarez-Lerma, F1
Nolla, J1
Palomar, M1
León, MA1
Tariq, M1
Moutaery, AA1
Arshaduddin, M1
Khan, HA1
Evans, DP1
Jacobs, S1
Shan, YS1
Sy, ED1
Wang, ST1
Lee, JC1
Lin, PW1
Sandven, P1
Qvist, H1
Skovlund, E1
Giercksky, KE1

Trials

1 trial available for fluconazole and Intestinal Perforation

ArticleYear
Significance of Candida recovered from intraoperative specimens in patients with intra-abdominal perforations.
    Critical care medicine, 2002, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Candidiasis; Double-Blind Method; Fem

2002

Other Studies

6 other studies available for fluconazole and Intestinal Perforation

ArticleYear
Risk factors for fluconazole-resistant invasive candidiasis in intensive care unit patients: An analysis from the China Survey of Candidiasis study.
    Journal of critical care, 2015, Volume: 30, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Candida; Candidiasis, Invasive; Carrier State; Ch

2015
Prophylactic fluconazole does not improve outcome in patients with purulent and fecal peritonitis due to lower gastrointestinal perforation.
    The American surgeon, 2010, Volume: 76, Issue:2

    Topics: Aged; Antifungal Agents; Dose-Response Relationship, Drug; Feces; Female; Fluconazole; Follow-Up Stu

2010
Decreasing candidaemia rate in abdominal surgery patients after introduction of fluconazole prophylaxis*.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2011, Volume: 17, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antifungal Agents; Ba

2011
[Treatment approach for fungal infections in critically ill patients admitted to intensive care units: results of a multicenter survey].
    Enfermedades infecciosas y microbiologia clinica, 2003, Volume: 21, Issue:2

    Topics: Amphotericin B; Antifungal Agents; Candidiasis; Case Management; Consensus Development Conferences a

2003
Fluconazole attenuates lung injury and mortality in a rat peritonitis model.
    Intensive care medicine, 2003, Volume: 29, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Ascitic Fluid; Disease Models, Animal; Dose-Response Relationship,

2003
Early presumptive therapy with fluconazole for occult Candida infection after gastrointestinal surgery.
    World journal of surgery, 2006, Volume: 30, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Candidiasis; Female; Fluconazole; Gastrointestina

2006