Page last updated: 2024-10-27

fluconazole and Innate Inflammatory Response

fluconazole has been researched along with Innate Inflammatory Response in 15 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Research Excerpts

ExcerptRelevanceReference
" Here, we report a case of a patient affected by extended cutaneous candidiasis diagnosed by culture examination; a JHR occurred after an accidental overdose of oral fluconazole."7.96A case of Jarisch-Herxheimer reaction in candidiasis treated with systemic fluconazole. ( Magri, F; Muscianese, M; Pranteda, G, 2020)
"Rats in Fp groups were given fluconazole in doses of 0 mg/kg, 3 mg/kg, 10 mg/kg, and 30 mg/kg by gavage 30 min before induction of peritonitis."7.72Fluconazole attenuates lung injury and mortality in a rat peritonitis model. ( Arshaduddin, M; Evans, DP; Jacobs, S; Khan, HA; Moutaery, AA; Tariq, M, 2003)
" Here, we report a case of a patient affected by extended cutaneous candidiasis diagnosed by culture examination; a JHR occurred after an accidental overdose of oral fluconazole."3.96A case of Jarisch-Herxheimer reaction in candidiasis treated with systemic fluconazole. ( Magri, F; Muscianese, M; Pranteda, G, 2020)
"Rats in Fp groups were given fluconazole in doses of 0 mg/kg, 3 mg/kg, 10 mg/kg, and 30 mg/kg by gavage 30 min before induction of peritonitis."3.72Fluconazole attenuates lung injury and mortality in a rat peritonitis model. ( Arshaduddin, M; Evans, DP; Jacobs, S; Khan, HA; Moutaery, AA; Tariq, M, 2003)
"Osteomyelitis is a bone inflammation that can be related to various infectious agents."3.01Cryptococcus neoformans osteomyelitis of the tibia: a case report and review of the literature. ( Ampadiotaki, MM; Diamantopoulou, K; Georgousi, K; Gourtzelidis, G; Kokkinis, C; Lelekis, M; Pallis, D; Papadakis, SA; Tatakis, F; Tsivelekas, K, 2023)
"Fluconazole treatment in utero decreased intestinal C."1.43Intra-amniotic Candida albicans infection induces mucosal injury and inflammation in the ovine fetal intestine. ( Hornef, MW; Jacobs, EM; Janssen, LE; Jobe, AH; Kallapur, SG; Kemp, MW; Kramer, BW; Newnham, JP; Nikiforou, M; Payne, MS; Saito, M; Wolfs, TG, 2016)
"Fluconazole treatment temporarily decreased the pulmonary and chorioamnion inflammatory responses."1.42Fluconazole treatment of intrauterine Candida albicans infection in fetal sheep. ( Jobe, AH; Kallapur, SG; Kemp, MW; Kramer, BW; Maneenil, G; Miura, Y; Newnham, JP; Payne, MS; Senthamarai Kannan, P, 2015)
"Treatment with Fluconazole for a period of four weeks successfully cured the infection."1.34Exacerbated inflammatory reaction to Trichophyton rubrum infection on an HIV-positive patient successfully treated with fluconazole. ( de Oliveira Teixeira, F; Mendoza, L; Vilela, L; Vilela, R, 2007)
"Fluconazole was labelled with (99m)Tc and radiochemical analysis showed less than 5% impurities."1.31Technetium-99m labelled fluconazole and antimicrobial peptides for imaging of Candida albicans and Aspergillus fumigatus infections. ( Lupetti, A; Mazzi, U; Nibbering, PH; Pauwels, EK; Welling, MM, 2002)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's4 (26.67)29.6817
2010's6 (40.00)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Samukawa, S3
Yoshimi, R3
Kojitani, N3
Uzawa, Y3
Takase-Minegishi, K3
Kirino, Y3
Soejima, Y3
Kato, H3
Nakajima, H3
Papadakis, SA1
Gourtzelidis, G1
Pallis, D1
Ampadiotaki, MM1
Tatakis, F1
Tsivelekas, K1
Georgousi, K1
Kokkinis, C1
Diamantopoulou, K1
Lelekis, M1
Muscianese, M1
Magri, F1
Pranteda, G2
Morais, EA1
Martins, EM1
Boelone, JN1
Gomes, DA1
Goes, AM1
Maneenil, G1
Payne, MS2
Senthamarai Kannan, P1
Kallapur, SG2
Kramer, BW2
Newnham, JP2
Miura, Y1
Jobe, AH2
Kemp, MW2
Qiu, X1
Zhang, F1
Yang, X1
Wu, N1
Jiang, W1
Li, X2
Liu, Y1
Schaller, M1
Friedrich, M1
Papini, M1
Pujol, RM1
Veraldi, S1
Nikiforou, M1
Jacobs, EM1
Hornef, MW1
Saito, M1
Janssen, LE1
Wolfs, TG1
Tariq, M1
Moutaery, AA1
Arshaduddin, M1
Khan, HA1
Evans, DP1
Jacobs, S1
Vilela, R1
de Oliveira Teixeira, F1
Vilela, L1
Mendoza, L1
Jafari, HS1
Sáez-Llorens, X1
Severien, C1
Parras, F1
Friedland, I1
Rinderknecht, S1
Ehrett, S1
Olsen, KD1
Abramowsky, C1
McCracken, GH1
Matsuyama, W1
Takenaga, S1
Nakahara, K1
Kawabata, M1
Iwakiri, Y1
Arimura, K1
Osame, M1
Bornstein, J1
Livnat, G1
Stolar, Z1
Abramovici, H1
Lupetti, A1
Welling, MM1
Mazzi, U1
Nibbering, PH1
Pauwels, EK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Vestibulitis Educational Seminar Trial Study"[NCT00278850]500 participants (Actual)Observational2006-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for fluconazole and Innate Inflammatory Response

ArticleYear
Cryptococcus neoformans osteomyelitis of the tibia: a case report and review of the literature.
    Journal of medical case reports, 2023, May-07, Volume: 17, Issue:1

    Topics: Cryptococcosis; Cryptococcus neoformans; Female; Fluconazole; Humans; Inflammation; Osteomyelitis; T

2023
Topical antifungal-corticosteroid combination therapy for the treatment of superficial mycoses: conclusions of an expert panel meeting.
    Mycoses, 2016, Volume: 59, Issue:6

    Topics: Administration, Topical; Adrenal Cortex Hormones; Antifungal Agents; Dermatomycoses; Drug Therapy, C

2016

Trials

1 trial available for fluconazole and Innate Inflammatory Response

ArticleYear
Pure versus complicated vulvar vestibulitis: a randomized trial of fluconazole treatment.
    Gynecologic and obstetric investigation, 2000, Volume: 50, Issue:3

    Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Inflammation; Vulvar Dise

2000

Other Studies

12 other studies available for fluconazole and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Cryptococcal meningitis with atypical paradoxical inflammatory reactions after antifungal treatment in acquired immune deficiency syndrome: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Retroviral Ag

2023
Cryptococcal meningitis with atypical paradoxical inflammatory reactions after antifungal treatment in acquired immune deficiency syndrome: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Retroviral Ag

2023
Cryptococcal meningitis with atypical paradoxical inflammatory reactions after antifungal treatment in acquired immune deficiency syndrome: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Retroviral Ag

2023
Cryptococcal meningitis with atypical paradoxical inflammatory reactions after antifungal treatment in acquired immune deficiency syndrome: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Retroviral Ag

2023
Cryptococcal meningitis with atypical paradoxical inflammatory reactions after antifungal treatment in acquired immune deficiency syndrome: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Retroviral Ag

2023
Cryptococcal meningitis with atypical paradoxical inflammatory reactions after antifungal treatment in acquired immune deficiency syndrome: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Retroviral Ag

2023
Cryptococcal meningitis with atypical paradoxical inflammatory reactions after antifungal treatment in acquired immune deficiency syndrome: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Retroviral Ag

2023
Cryptococcal meningitis with atypical paradoxical inflammatory reactions after antifungal treatment in acquired immune deficiency syndrome: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Retroviral Ag

2023
Cryptococcal meningitis with atypical paradoxical inflammatory reactions after antifungal treatment in acquired immune deficiency syndrome: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Retroviral Ag

2023
A case of Jarisch-Herxheimer reaction in candidiasis treated with systemic fluconazole.
    Dermatologic therapy, 2020, Volume: 33, Issue:2

    Topics: Anti-Bacterial Agents; Candidiasis; Fluconazole; Humans; Inflammation; Syphilis

2020
Immunization with recombinant Pb27 protein reduces the levels of pulmonary fibrosis caused by the inflammatory response against Paracoccidioides brasiliensis.
    Mycopathologia, 2015, Volume: 179, Issue:1-2

    Topics: Animals; Antifungal Agents; Antigens, Fungal; Caspase 3; Collagen; Fluconazole; Fungal Proteins; Fun

2015
Fluconazole treatment of intrauterine Candida albicans infection in fetal sheep.
    Pediatric research, 2015, Volume: 77, Issue:6

    Topics: Analysis of Variance; Animals; Antifungal Agents; Candidiasis; Female; Fetal Diseases; Fluconazole;

2015
Changes in the composition of intestinal fungi and their role in mice with dextran sulfate sodium-induced colitis.
    Scientific reports, 2015, May-27, Volume: 5

    Topics: Acute Disease; Animals; beta-Glucans; Colitis; Colon; Cytokines; Dextran Sulfate; Discriminant Analy

2015
Intra-amniotic Candida albicans infection induces mucosal injury and inflammation in the ovine fetal intestine.
    Scientific reports, 2016, 07-14, Volume: 6

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Chorioamnionitis; Cytokines; Female; Fetu

2016
Fluconazole attenuates lung injury and mortality in a rat peritonitis model.
    Intensive care medicine, 2003, Volume: 29, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Ascitic Fluid; Disease Models, Animal; Dose-Response Relationship,

2003
Exacerbated inflammatory reaction to Trichophyton rubrum infection on an HIV-positive patient successfully treated with fluconazole.
    Mycopathologia, 2007, Volume: 163, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Female; Fluconazole; HIV Infections

2007
Effects of antifungal therapy on inflammation, sterilization, and histology in experimental Candida albicans meningitis.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:1

    Topics: Amphotericin B; Animals; Antifungal Agents; Brain; Candida albicans; Candidiasis; Cytokines; Flucona

1994
Idiopathic hypoparathyroidism with fungal seminal vesiculitis.
    Internal medicine (Tokyo, Japan), 1997, Volume: 36, Issue:2

    Topics: Adult; Antifungal Agents; Fluconazole; Genital Diseases, Male; Humans; Hypoparathyroidism; Inflammat

1997
Technetium-99m labelled fluconazole and antimicrobial peptides for imaging of Candida albicans and Aspergillus fumigatus infections.
    European journal of nuclear medicine and molecular imaging, 2002, Volume: 29, Issue:5

    Topics: Animals; Aspergillosis; Aspergillus fumigatus; Candidiasis; Diagnosis, Differential; Fluconazole; Hu

2002