fluconazole has been researched along with Hypokalemia in 8 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This case report describes the successful management of a patient with diabetic ketoacidosis, who developed torsades de pointes leading to nine cardiac arrests secondary to intravenous fluconazole administration on a background of hypokalaemia and hypocalcaemia." | 7.75 | Fluconazole-induced recurrent ventricular fibrillation leading to multiple cardiac arrests. ( Arora, MK; Chakravarty, C; Singh, PM; Trikha, A, 2009) |
| "We describe 2 patients with acute promyelocytic leukemia (APL) in whom torsade de pointes (TdP) developed during treatment with arsenic trioxide." | 7.73 | Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy. ( Kobayashi, M; Naito, K; Nakamura, S; Ohnishi, K; Ohno, R; Sahara, N; Shigeno, K; Shinjo, K; Takeshita, A; Tobita, T, 2006) |
| "This case report describes the successful management of a patient with diabetic ketoacidosis, who developed torsades de pointes leading to nine cardiac arrests secondary to intravenous fluconazole administration on a background of hypokalaemia and hypocalcaemia." | 3.75 | Fluconazole-induced recurrent ventricular fibrillation leading to multiple cardiac arrests. ( Arora, MK; Chakravarty, C; Singh, PM; Trikha, A, 2009) |
| "We describe 2 patients with acute promyelocytic leukemia (APL) in whom torsade de pointes (TdP) developed during treatment with arsenic trioxide." | 3.73 | Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy. ( Kobayashi, M; Naito, K; Nakamura, S; Ohnishi, K; Ohno, R; Sahara, N; Shigeno, K; Shinjo, K; Takeshita, A; Tobita, T, 2006) |
| "Our previous study explored Amphotericin B (AMB) plus 5-flucytosine (5-FC) combined with fluconazole (FLU) therapy in the induction period, which seemed to be better than the previous AMB + 5-FC antifungal therapy in non-HIV and non-transplant-associated CM." | 1.72 | Amphotericin B plus fluorocytosine combined with voriconazole for the treatment of non-HIV and non-transplant-associated cryptococcal meningitis: a retrospective study. ( Jiang, Y; Li, M; Liu, J; Peng, F; Su, X; Wang, A; Wang, Y; Xu, X; Yang, L, 2022) |
| " The occurrence of LAMB-attributable renal toxicity was investigated; infants withdrawn from treatment for development of adverse effects or toxicity were identified." | 1.38 | Liposomal amphotericin B does not induce nephrotoxicity or renal function impairment in premature neonates. ( Antonucci, R; Fanos, V; Farina, D; Franco, C; Galletto, P; Gallo, E; Manzoni, P; Rizzollo, S, 2012) |
| "Fluconazole was used in 48% of the treatment episodes, amphotericin B in 46%, itraconazole in 4." | 1.34 | Drug-drug interactions with systemic antifungals in clinical practice. ( Abouelfath, A; Depont, F; Dupon, M; Dutronc, H; Galpérine, T; Giauque, E; Hébert, G; Moore, N; Ragnaud, JM; Valentino, R; Vargas, F, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, J | 2 |
| Su, X | 1 |
| Yang, L | 1 |
| Wang, Y | 1 |
| Wang, A | 1 |
| Xu, X | 1 |
| Li, M | 1 |
| Jiang, Y | 1 |
| Peng, F | 1 |
| Chakravarty, C | 1 |
| Singh, PM | 1 |
| Trikha, A | 1 |
| Arora, MK | 1 |
| Manzoni, P | 1 |
| Galletto, P | 1 |
| Rizzollo, S | 1 |
| Franco, C | 1 |
| Gallo, E | 1 |
| Antonucci, R | 1 |
| Fanos, V | 1 |
| Farina, D | 1 |
| Zeuli, JD | 1 |
| Wilson, JW | 1 |
| Estes, LL | 1 |
| Hinterseer, M | 1 |
| Irlbeck, M | 1 |
| Ney, L | 1 |
| Beckmann, BM | 1 |
| Pfeufer, A | 1 |
| Steinbeck, G | 1 |
| Kaab, S | 1 |
| Naito, K | 1 |
| Kobayashi, M | 1 |
| Sahara, N | 1 |
| Shigeno, K | 1 |
| Nakamura, S | 1 |
| Shinjo, K | 1 |
| Tobita, T | 1 |
| Takeshita, A | 1 |
| Ohno, R | 1 |
| Ohnishi, K | 1 |
| Depont, F | 1 |
| Vargas, F | 1 |
| Dutronc, H | 1 |
| Giauque, E | 1 |
| Ragnaud, JM | 1 |
| Galpérine, T | 1 |
| Abouelfath, A | 1 |
| Valentino, R | 1 |
| Dupon, M | 1 |
| Hébert, G | 1 |
| Moore, N | 1 |
| Kidd, D | 1 |
| Ranaghan, EA | 1 |
| Morris, TC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial of Tamoxifen Combined With Amphotericin B and Fluconazole for Cryptococcal Meningitis[NCT03112031] | Phase 2 | 50 participants (Actual) | Interventional | 2017-10-10 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for fluconazole and Hypokalemia
| Article | Year |
|---|---|
Amphotericin B plus fluorocytosine combined with voriconazole for the treatment of non-HIV and non-transplant-associated cryptococcal meningitis: a retrospective study.
Topics: Amphotericin B; Antifungal Agents; Drug Therapy, Combination; Fluconazole; Flucytosine; Humans; Hypo | 2022 |
Fluconazole-induced recurrent ventricular fibrillation leading to multiple cardiac arrests.
Topics: Adult; Antifungal Agents; Diabetic Ketoacidosis; Female; Fluconazole; Heart Arrest; Humans; Hypocalc | 2009 |
Liposomal amphotericin B does not induce nephrotoxicity or renal function impairment in premature neonates.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Cohort Studies; Creatinine; Fluconazole; Humans; Hyp | 2012 |
Effect of combined fluoroquinolone and azole use on QT prolongation in hematology patients.
Topics: Adult; Aged; Antifungal Agents; Drug Administration Schedule; Drug Therapy, Combination; Electrocard | 2013 |
Acute respiratory distress syndrome with transiently impaired left ventricular function and Torsades de Pointes arrhythmia unmasking congenital long QT syndrome in a 25-yr-old woman.
Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Echocardiography; ERG1 Potassium Channel; Erythromy | 2006 |
Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy.
Topics: Adult; Anthracyclines; Antifungal Agents; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cardi | 2006 |
Drug-drug interactions with systemic antifungals in clinical practice.
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Creatinine; Cyclosporine; Drug Interactions; Female; | 2007 |
Hypokalaemia in patients with acute myeloid leukaemia after treatment with fluconazole.
Topics: Administration, Oral; Antifungal Agents; Fluconazole; Humans; Hypokalemia; Leukemia, Myeloid, Acute; | 1989 |