fluconazole has been researched along with Hypertension, Pulmonary in 1 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We successfully characterized the PK of sildenafil and DMS in premature infants and applied the model to inform dosing for a follow-up, phase II study." | 2.90 | Population pharmacokinetics of sildenafil in extremely premature infants. ( Ambalavanan, N; Atz, A; Cohen-Wolkowiez, M; Gaedigk, R; Ge, S; Gonzalez, D; Hornik, CD; Hornik, CP; Laughon, MM; Martz, K; Mills, M; Mundakel, G; Poindexter, BB; Smith, PB; Sokol, GM; Stewart, D, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gonzalez, D | 1 |
| Laughon, MM | 1 |
| Smith, PB | 1 |
| Ge, S | 1 |
| Ambalavanan, N | 1 |
| Atz, A | 1 |
| Sokol, GM | 1 |
| Hornik, CD | 1 |
| Stewart, D | 1 |
| Mundakel, G | 1 |
| Poindexter, BB | 1 |
| Gaedigk, R | 1 |
| Mills, M | 1 |
| Cohen-Wolkowiez, M | 1 |
| Martz, K | 1 |
| Hornik, CP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety of Sildenafil in Premature Infants With Severe Bronchopulmonary Dysplasia[NCT04447989] | Phase 2 | 120 participants (Anticipated) | Interventional | 2021-05-27 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for fluconazole and Hypertension, Pulmonary
| Article | Year |
|---|---|
Population pharmacokinetics of sildenafil in extremely premature infants.
Topics: Administration, Oral; Cohort Studies; Cytochrome P-450 CYP3A; Fluconazole; Gestational Age; Humans; | 2019 |