fluconazole has been researched along with Heart Defects, Congenital in 6 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because half of all pregnancies are unplanned and pregnant women have an increased risk of VVC recurrence, the likelihood of inadvertently being exposed to fluconazole in pregnancy is increased." | 4.91 | Exposure to fluconazole and risk of congenital malformations in the offspring: A systematic review and meta-analysis. ( Alsaad, AM; Kaplan, YC; Koren, G, 2015) |
| "Fluconazole is a bis-triazole agent used in the treatment of superficial and systemic fungal infections, with vaginal candidiasis being one of the commonest indications to fluconazole treatment." | 2.72 | Maternal use of fluconazole and congenital malformations in the progeny: A meta-analysis of the literature. ( Budani, MC; Di Marzio, M; Fensore, S; Tiboni, GM, 2021) |
| "Fungal peritonitis is a rare but serious complication in children on peritoneal dialysis." | 1.35 | Acremonium spp. peritonitis in an infant. ( Atalay, S; Ciftçi, E; Düzenli, F; Ekim, M; Galip, N; Güriz, H; Kendirli, T; Ozçakar, ZB; Tapisiz, A; Tutar, E; Uçar, T, 2008) |
| "Fluconazole has been associated with various teratisms in animals, including craniofacial ossification defects, thin, wavy ribs, and renal pelvis defects." | 1.29 | Fluconazole-induced congenital anomalies in three infants. ( Abraham, J; Andersen, HF; Bartley, JA; Blomquist, IK; Pursley, TJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Budani, MC | 1 |
| Fensore, S | 1 |
| Di Marzio, M | 1 |
| Tiboni, GM | 1 |
| Alsaad, AM | 1 |
| Kaplan, YC | 1 |
| Koren, G | 1 |
| Gardner, AH | 1 |
| Prodhan, P | 1 |
| Stovall, SH | 1 |
| Gossett, JM | 1 |
| Stern, JE | 1 |
| Wilson, CD | 1 |
| Fiser, RT | 1 |
| Kendirli, T | 1 |
| Ciftçi, E | 1 |
| Ekim, M | 1 |
| Galip, N | 1 |
| Düzenli, F | 1 |
| Ozçakar, ZB | 1 |
| Tapisiz, A | 1 |
| Uçar, T | 1 |
| Tutar, E | 1 |
| Güriz, H | 1 |
| Atalay, S | 1 |
| Pursley, TJ | 1 |
| Blomquist, IK | 1 |
| Abraham, J | 1 |
| Andersen, HF | 1 |
| Bartley, JA | 1 |
| Lai, PH | 1 |
| Lin, SM | 1 |
| Pan, HB | 1 |
| Yang, CF | 1 |
2 reviews available for fluconazole and Heart Defects, Congenital
| Article | Year |
|---|---|
Maternal use of fluconazole and congenital malformations in the progeny: A meta-analysis of the literature.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Antifungal Agents; Candidiasis, Vulvovaginal; Do | 2021 |
Exposure to fluconazole and risk of congenital malformations in the offspring: A systematic review and meta-analysis.
Topics: Abnormalities, Drug-Induced; Antifungal Agents; Candidiasis, Vulvovaginal; Craniofacial Abnormalitie | 2015 |
4 other studies available for fluconazole and Heart Defects, Congenital
| Article | Year |
|---|---|
Fungal infections and antifungal prophylaxis in pediatric cardiac extracorporeal life support.
Topics: Antifungal Agents; Arkansas; Cardiac Surgical Procedures; Chi-Square Distribution; Cross Infection; | 2012 |
Acremonium spp. peritonitis in an infant.
Topics: Acremonium; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Down Syndrome; Fluconazole; He | 2008 |
Fluconazole-induced congenital anomalies in three infants.
Topics: Abnormalities, Drug-Induced; Adult; Antifungal Agents; Bone and Bones; Coccidioidomycosis; Face; Fem | 1996 |
Disseminated miliary cerebral candidiasis.
Topics: Amphotericin B; Antifungal Agents; Brain; Candidiasis; Child, Preschool; Combined Modality Therapy; | 1997 |