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fluconazole and Heart Defects, Congenital

fluconazole has been researched along with Heart Defects, Congenital in 6 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.

Research Excerpts

ExcerptRelevanceReference
" Because half of all pregnancies are unplanned and pregnant women have an increased risk of VVC recurrence, the likelihood of inadvertently being exposed to fluconazole in pregnancy is increased."4.91Exposure to fluconazole and risk of congenital malformations in the offspring: A systematic review and meta-analysis. ( Alsaad, AM; Kaplan, YC; Koren, G, 2015)
"Fluconazole is a bis-triazole agent used in the treatment of superficial and systemic fungal infections, with vaginal candidiasis being one of the commonest indications to fluconazole treatment."2.72Maternal use of fluconazole and congenital malformations in the progeny: A meta-analysis of the literature. ( Budani, MC; Di Marzio, M; Fensore, S; Tiboni, GM, 2021)
"Fungal peritonitis is a rare but serious complication in children on peritoneal dialysis."1.35Acremonium spp. peritonitis in an infant. ( Atalay, S; Ciftçi, E; Düzenli, F; Ekim, M; Galip, N; Güriz, H; Kendirli, T; Ozçakar, ZB; Tapisiz, A; Tutar, E; Uçar, T, 2008)
"Fluconazole has been associated with various teratisms in animals, including craniofacial ossification defects, thin, wavy ribs, and renal pelvis defects."1.29Fluconazole-induced congenital anomalies in three infants. ( Abraham, J; Andersen, HF; Bartley, JA; Blomquist, IK; Pursley, TJ, 1996)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Budani, MC1
Fensore, S1
Di Marzio, M1
Tiboni, GM1
Alsaad, AM1
Kaplan, YC1
Koren, G1
Gardner, AH1
Prodhan, P1
Stovall, SH1
Gossett, JM1
Stern, JE1
Wilson, CD1
Fiser, RT1
Kendirli, T1
Ciftçi, E1
Ekim, M1
Galip, N1
Düzenli, F1
Ozçakar, ZB1
Tapisiz, A1
Uçar, T1
Tutar, E1
Güriz, H1
Atalay, S1
Pursley, TJ1
Blomquist, IK1
Abraham, J1
Andersen, HF1
Bartley, JA1
Lai, PH1
Lin, SM1
Pan, HB1
Yang, CF1

Reviews

2 reviews available for fluconazole and Heart Defects, Congenital

ArticleYear
Maternal use of fluconazole and congenital malformations in the progeny: A meta-analysis of the literature.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 100

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Antifungal Agents; Candidiasis, Vulvovaginal; Do

2021
Exposure to fluconazole and risk of congenital malformations in the offspring: A systematic review and meta-analysis.
    Reproductive toxicology (Elmsford, N.Y.), 2015, Volume: 52

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Candidiasis, Vulvovaginal; Craniofacial Abnormalitie

2015

Other Studies

4 other studies available for fluconazole and Heart Defects, Congenital

ArticleYear
Fungal infections and antifungal prophylaxis in pediatric cardiac extracorporeal life support.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 143, Issue:3

    Topics: Antifungal Agents; Arkansas; Cardiac Surgical Procedures; Chi-Square Distribution; Cross Infection;

2012
Acremonium spp. peritonitis in an infant.
    Mycoses, 2008, Volume: 51, Issue:5

    Topics: Acremonium; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Down Syndrome; Fluconazole; He

2008
Fluconazole-induced congenital anomalies in three infants.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Antifungal Agents; Bone and Bones; Coccidioidomycosis; Face; Fem

1996
Disseminated miliary cerebral candidiasis.
    AJNR. American journal of neuroradiology, 1997, Volume: 18, Issue:7

    Topics: Amphotericin B; Antifungal Agents; Brain; Candidiasis; Child, Preschool; Combined Modality Therapy;

1997