fluconazole has been researched along with Electrocardiogram QT Prolonged in 13 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present the occurrence of 'torsade de pointes' induced by the combination of peroperative fluconazole administration and sevoflurane anesthesia in a patient with 'long QT syndrome' (LQTS) scheduled for resection of a sacral abscess." | 7.77 | Torsade de pointes during sevoflurane anesthesia and fluconazole infusion in a patient with long QT syndrome. A case report. ( Bracke, FA; Tacken, MC; Van Zundert, AA, 2011) |
| "We present the occurrence of 'torsade de pointes' induced by the combination of peroperative fluconazole administration and sevoflurane anesthesia in a patient with 'long QT syndrome' (LQTS) scheduled for resection of a sacral abscess." | 3.77 | Torsade de pointes during sevoflurane anesthesia and fluconazole infusion in a patient with long QT syndrome. A case report. ( Bracke, FA; Tacken, MC; Van Zundert, AA, 2011) |
| " Participants received standard care - amphotericin combined with fluconazole for the first 2 weeks - or standard care plus tamoxifen 300 mg/day." | 3.01 | An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis. ( Beardsley, J; Binh, TQ; Chau, NVV; Day, JN; Geskus, R; Hope, W; Hung, LQ; Kestelyn, E; Krysan, D; Lalloo, DG; Lan, NPH; Mai, NTH; Ngan, NTT; Phu, NH; Tai, LTH; Thanh Hoang Le, N; Thwaites, GE; Trieu, PH; Tung, NLN; Van Anh, D; Van, NTT; Vi Vi, NN; White, NJ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Ngan, NTT | 1 |
| Thanh Hoang Le, N | 1 |
| Vi Vi, NN | 1 |
| Van, NTT | 1 |
| Mai, NTH | 1 |
| Van Anh, D | 1 |
| Trieu, PH | 1 |
| Lan, NPH | 1 |
| Phu, NH | 1 |
| Chau, NVV | 1 |
| Lalloo, DG | 1 |
| Hope, W | 1 |
| Beardsley, J | 1 |
| White, NJ | 1 |
| Geskus, R | 1 |
| Thwaites, GE | 1 |
| Krysan, D | 1 |
| Tai, LTH | 1 |
| Kestelyn, E | 1 |
| Binh, TQ | 1 |
| Hung, LQ | 1 |
| Tung, NLN | 1 |
| Day, JN | 1 |
| Ünal Yüksekgönül, A | 1 |
| Ertuğrul, İ | 1 |
| Karagöz, T | 1 |
| Berger, FA | 1 |
| Monadian, N | 1 |
| de Groot, NMS | 1 |
| Santbergen, B | 1 |
| van der Sijs, H | 1 |
| Becker, ML | 1 |
| Broers, AEC | 1 |
| van Gelder, T | 1 |
| van den Bemt, PMLA | 1 |
| Tilton, JJ | 1 |
| Sadr, R | 1 |
| Groo, VL | 1 |
| Buch, T | 1 |
| Andersen, SE | 1 |
| Wang, J | 1 |
| Wang, G | 1 |
| Quan, X | 1 |
| Ruan, L | 1 |
| Liu, Y | 1 |
| Ruan, Y | 1 |
| Liu, N | 1 |
| Zhang, C | 1 |
| Bai, R | 1 |
| Vandael, E | 1 |
| Vandenberk, B | 1 |
| Vandenberghe, J | 1 |
| Spriet, I | 1 |
| Willems, R | 1 |
| Foulon, V | 1 |
| Tacken, MC | 1 |
| Bracke, FA | 1 |
| Van Zundert, AA | 1 |
| Zeuli, JD | 1 |
| Wilson, JW | 1 |
| Estes, LL | 1 |
| Hrovatin, E | 1 |
| Zardo, F | 1 |
| Brieda, M | 1 |
| Dametto, E | 1 |
| Piazza, R | 1 |
| Antonini-Canterin, F | 1 |
| Cassin, M | 1 |
| Meneguzzo, N | 1 |
| Viel, E | 1 |
| Lestuzzi, C | 1 |
| Di Gennaro, G | 1 |
| Nicolosi, GL | 1 |
| Hinterseer, M | 1 |
| Irlbeck, M | 1 |
| Ney, L | 1 |
| Beckmann, BM | 1 |
| Pfeufer, A | 1 |
| Steinbeck, G | 1 |
| Kaab, S | 1 |
| Wassmann, S | 1 |
| Nickenig, G | 1 |
| Böhm, M | 1 |
| Dorsey, ST | 1 |
| Biblo, LA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial of Tamoxifen Combined With Amphotericin B and Fluconazole for Cryptococcal Meningitis[NCT03112031] | Phase 2 | 50 participants (Actual) | Interventional | 2017-10-10 | Completed | ||
| Risk of QT-prolongation and Torsade de Pointes in Patients Treated With Acute Medication in a University Hospital[NCT02068170] | 178 participants (Actual) | Observational | 2014-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for fluconazole and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis.
Topics: Adult; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Drug Therapy, Combination; Female | 2021 |
12 other studies available for fluconazole and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Fluconazole-associated QT interval prolongation and Torsades de Pointes in a paediatric patient.
Topics: Adolescent; Child; Electrocardiography; Female; Fluconazole; Humans; Long QT Syndrome; Tachycardia, | 2021 |
QTc prolongation during ciprofloxacin and fluconazole combination therapy: prevalence and associated risk factors.
Topics: Ciprofloxacin; Drug Therapy, Combination; Electrocardiography; Female; Fluconazole; Heart Rate; Huma | 2018 |
Concomitant use of levofloxacin and fluconazole leading to possible torsades de pointes.
Topics: Adult; Electrocardiography; Female; Fluconazole; Humans; Levofloxacin; Long QT Syndrome; Risk Factor | 2019 |
[Combination therapy with fluconazole and other QTc-prolonging drugs increase the QTc interval].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antifungal Agents; Clarithromycin; | 2015 |
Fluconazole-induced long QT syndrome via impaired human ether-a-go-go-related gene (hERG) protein trafficking in rabbits.
Topics: Animals; Disease Models, Animal; Electrocardiography; ERG1 Potassium Channel; Female; Fluconazole; H | 2017 |
Development of a risk score for QTc-prolongation: the RISQ-PATH study.
Topics: Aged; Female; Fluconazole; Haloperidol; Humans; Levofloxacin; Long QT Syndrome; Male; Models, Statis | 2017 |
Torsade de pointes during sevoflurane anesthesia and fluconazole infusion in a patient with long QT syndrome. A case report.
Topics: Abscess; Aged; Anesthetics, Inhalation; Antifungal Agents; Electrocardiography; Female; Fluconazole; | 2011 |
Effect of combined fluoroquinolone and azole use on QT prolongation in hematology patients.
Topics: Adult; Aged; Antifungal Agents; Drug Administration Schedule; Drug Therapy, Combination; Electrocard | 2013 |
[Long QT and torsade de pointes in a patient with acquired human immunodeficiency virus infection in multitherapy with drugs affecting cytochrome P450].
Topics: Acquired Immunodeficiency Syndrome; Analgesics, Opioid; Antifungal Agents; Antiretroviral Therapy, H | 2004 |
Acute respiratory distress syndrome with transiently impaired left ventricular function and Torsades de Pointes arrhythmia unmasking congenital long QT syndrome in a 25-yr-old woman.
Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Echocardiography; ERG1 Potassium Channel; Erythromy | 2006 |
Long QT syndrome and torsade de pointes in a patient receiving fluconazole.
Topics: Antifungal Agents; Female; Fluconazole; Humans; Long QT Syndrome; Middle Aged; Torsades de Pointes | 1999 |
Prolonged QT interval and torsades de pointes caused by the combination of fluconazole and amitriptyline.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antifungal Agents; Drug Interactions; Electrocardio | 2000 |