fluconazole has been researched along with Down Syndrome in 2 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fungal peritonitis is a rare but serious complication in children on peritoneal dialysis." | 1.35 | Acremonium spp. peritonitis in an infant. ( Atalay, S; Ciftçi, E; Düzenli, F; Ekim, M; Galip, N; Güriz, H; Kendirli, T; Ozçakar, ZB; Tapisiz, A; Tutar, E; Uçar, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kendirli, T | 1 |
| Ciftçi, E | 1 |
| Ekim, M | 1 |
| Galip, N | 1 |
| Düzenli, F | 1 |
| Ozçakar, ZB | 1 |
| Tapisiz, A | 1 |
| Uçar, T | 1 |
| Tutar, E | 1 |
| Güriz, H | 1 |
| Atalay, S | 1 |
| Posteraro, B | 1 |
| Valentini, P | 1 |
| Delogu, A | 1 |
| De, RG | 1 |
| Boccacci, S | 1 |
| Sanguinetti, M | 1 |
| Nacci, A | 1 |
| Sopo, SM | 1 |
| Ranno, O | 1 |
| Morace, G | 1 |
| Fadda, G | 1 |
2 other studies available for fluconazole and Down Syndrome
| Article | Year |
|---|---|
Acremonium spp. peritonitis in an infant.
Topics: Acremonium; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Down Syndrome; Fluconazole; He | 2008 |
Candida albicans endocarditis diagnosed by PCR-based molecular assay in a critically ill pediatric patient.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Child, Preschool; Critical Illness; Down Syndrome; | 2002 |