fluconazole has been researched along with Disorders of Excessive Somnolence in 1 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
| Excerpt | Relevance | Reference |
|---|---|---|
| " When fluconazole, a potent inhibitor of CYP2C9, was added to the treatment regimen, the patient developed ataxia, tremor, fatigue, slurred speech and somnolence, indicating phenytoin intoxication." | 3.76 | Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9. ( Bergman, U; Bertilsson, L; Engström Hellgren, K; Helldén, A; Masquelier, M; Nilsson Remahl, I; Odar-Cederlöf, I; Ramsjö, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Helldén, A | 1 |
| Bergman, U | 1 |
| Engström Hellgren, K | 1 |
| Masquelier, M | 1 |
| Nilsson Remahl, I | 1 |
| Odar-Cederlöf, I | 1 |
| Ramsjö, M | 1 |
| Bertilsson, L | 1 |
1 other study available for fluconazole and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.
Topics: Alleles; Angiotensin II Type 1 Receptor Blockers; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; At | 2010 |