fluconazole has been researched along with Discitis in 15 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Discitis: Inflammation of an INTERVERTEBRAL DISC or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this patient with severe, chronic polymicrobial spine infection with epidural abscess and CSF fistula due to multidrug-resistant organisms, the cure was achieved with long-term antimicrobial specific therapy with quinupristin-dalfopristin (50 days) and linezolid (100 days) with mild side effects." | 7.73 | Nosocomial spondylodiskitis with epidural abscess and CSF fistula cured with quinupristin/dalfopristin and linezolid. ( Altobelli, G; Belfiori, B; Malincarne, L; Marroni, M; Papili, R; Stagni, G; Tinca, M, 2006) |
| "A case of Candida albicans spondylodiscitis in a 20-year-old female liver transplant recipient is reported." | 5.30 | Fluconazole therapy in Candida albicans spondylodiscitis. ( Nielsen, H; Rössel, P; Schønheyder, HC, 1998) |
| " In this patient with severe, chronic polymicrobial spine infection with epidural abscess and CSF fistula due to multidrug-resistant organisms, the cure was achieved with long-term antimicrobial specific therapy with quinupristin-dalfopristin (50 days) and linezolid (100 days) with mild side effects." | 3.73 | Nosocomial spondylodiskitis with epidural abscess and CSF fistula cured with quinupristin/dalfopristin and linezolid. ( Altobelli, G; Belfiori, B; Malincarne, L; Marroni, M; Papili, R; Stagni, G; Tinca, M, 2006) |
| "We present another case of infectious spondylodiscitis due to B." | 2.45 | Spondylodiscitis due to an emergent fungal pathogen: Blastoschizomyces capitatus, a case report and review of the literature. ( Celik, AD; Kantarcioglu, S; Mert, A; Ozaras, R; Ozturk, R; Tabak, F, 2009) |
| "Candida species rarely cause spondylodiscitis." | 2.42 | An unusual cause of vertebral osteomyelitis: Candida species. ( Bouchuiguir-Wafa, K; Garbino, J; Lew, D; Rohner, P; Schnyder, I, 2003) |
| "In 60% of the cases, candidal spondylodiskitis was a late complication of candidemia (mean delay, 5." | 2.39 | Spondylodiskitis due to Candida albicans: report of two patients who were successfully treated with fluconazole and review of the literature. ( Bourée, P; Charpentier, B; Dupont, B; Hennequin, C; Hiesse, C, 1996) |
| "Fungal spondylodiscitis is often because of Candida albicans or other common Candida species, whereas unusual strains such as Candida sake are often thought to be nonpathogenic." | 1.37 | Candida sake as the causative agent of spondylodiscitis in a hemodialysis patient. ( Benecchi, M; Buzio, C; De Filippo, M; Maggiore, U; Palmisano, A; Vaglio, A, 2011) |
| "Discitis or epidural abscess after discogram is a rare but known complication." | 1.37 | Candida lusitaniae discitis after discogram in an immunocompetent patient. ( Hogan, MV; Shen, FH; Werner, BC, 2011) |
| "Fungal spondylodiskitis (inflammation of intervertebral disk tissue and adjacent vertebrae) is rare, particularly in immunocompetent patients." | 1.35 | Fungal thoracic Spondylodiskitis in an immunocompetent 14-year-old girl. ( Aki, K; Asano, T; Fujino, O; Hatori, T; Kuwabara, K, 2009) |
| "To report the first case of T." | 1.35 | Postoperative Trichosporon asahii spondylodiscitis after open lumbar discectomy: a case report. ( Choi, SM; Ha, KY; Kim, KW; Kim, MS; Lee, JS, 2008) |
| "A case of Candida albicans spondylodiscitis in a 20-year-old female liver transplant recipient is reported." | 1.30 | Fluconazole therapy in Candida albicans spondylodiscitis. ( Nielsen, H; Rössel, P; Schønheyder, HC, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 8 (53.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Celik, AD | 1 |
| Ozaras, R | 1 |
| Kantarcioglu, S | 1 |
| Mert, A | 1 |
| Tabak, F | 1 |
| Ozturk, R | 1 |
| Rachapalli, SM | 1 |
| Malaiya, R | 1 |
| Mohd, TA | 1 |
| Hughes, RA | 1 |
| Asano, T | 1 |
| Hatori, T | 1 |
| Kuwabara, K | 1 |
| Aki, K | 1 |
| Fujino, O | 1 |
| Palmisano, A | 1 |
| Benecchi, M | 1 |
| De Filippo, M | 1 |
| Maggiore, U | 1 |
| Buzio, C | 1 |
| Vaglio, A | 1 |
| Werner, BC | 1 |
| Hogan, MV | 1 |
| Shen, FH | 1 |
| Garbino, J | 1 |
| Schnyder, I | 1 |
| Lew, D | 1 |
| Bouchuiguir-Wafa, K | 1 |
| Rohner, P | 1 |
| Marroni, M | 1 |
| Tinca, M | 1 |
| Belfiori, B | 1 |
| Altobelli, G | 1 |
| Malincarne, L | 1 |
| Papili, R | 1 |
| Stagni, G | 1 |
| Voigt, C | 1 |
| Lill, H | 1 |
| Frentiu, E | 1 |
| Petitfrere, M | 1 |
| May, T | 1 |
| Rabaud, C | 1 |
| Kim, KW | 1 |
| Ha, KY | 1 |
| Kim, MS | 1 |
| Choi, SM | 1 |
| Lee, JS | 1 |
| Waltzing-Koudine, L | 1 |
| Breville, P | 1 |
| Rajzbaum, G | 1 |
| Waltzing, P | 1 |
| Coates, JR | 1 |
| Hennequin, C | 1 |
| Bourée, P | 1 |
| Hiesse, C | 1 |
| Dupont, B | 1 |
| Charpentier, B | 1 |
| Rössel, P | 1 |
| Schønheyder, HC | 1 |
| Nielsen, H | 1 |
| Malinowska, B | 1 |
| Stepien, A | 1 |
| Sasiadek, M | 1 |
| Podemski, R | 1 |
3 reviews available for fluconazole and Discitis
| Article | Year |
|---|---|
Spondylodiscitis due to an emergent fungal pathogen: Blastoschizomyces capitatus, a case report and review of the literature.
Topics: Aged; Amphotericin B; Antifungal Agents; Dipodascus; Discitis; Fluconazole; Humans; Itraconazole; Ke | 2009 |
An unusual cause of vertebral osteomyelitis: Candida species.
Topics: Aged; Amphotericin B; Antifungal Agents; Candida; Candidiasis; Discitis; Female; Fluconazole; Follow | 2003 |
Spondylodiskitis due to Candida albicans: report of two patients who were successfully treated with fluconazole and review of the literature.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Discitis; Female; Fluconazole; Fungemia; Humans; K | 1996 |
12 other studies available for fluconazole and Discitis
| Article | Year |
|---|---|
Successful treatment of Candida discitis with 5-flucytosine and fluconazole.
Topics: Antifungal Agents; Candidemia; Discitis; Female; Fluconazole; Flucytosine; Humans; Middle Aged | 2010 |
Fungal thoracic Spondylodiskitis in an immunocompetent 14-year-old girl.
Topics: Adolescent; Antifungal Agents; Discitis; Female; Fluconazole; Humans; Immunocompetence; Mycoses; Tho | 2009 |
Candida sake as the causative agent of spondylodiscitis in a hemodialysis patient.
Topics: Antifungal Agents; Candida; Candidiasis; Discitis; Female; Fluconazole; Humans; Kidney Failure, Chro | 2011 |
Candida lusitaniae discitis after discogram in an immunocompetent patient.
Topics: Antifungal Agents; Candida; Candidiasis; Discitis; Epidural Abscess; Female; Fluconazole; Humans; Im | 2011 |
Nosocomial spondylodiskitis with epidural abscess and CSF fistula cured with quinupristin/dalfopristin and linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Bacteria; Cerebrospinal Fluid; Combined Modality Therapy; Cross I | 2006 |
[Candida albicans induced spondylodiscitis of the cervical spine of a polytraumatized patient].
Topics: Adult; Antifungal Agents; Candidiasis; Cervical Vertebrae; Combined Modality Therapy; Discitis; Epid | 2006 |
[Two cases of spondylodiscitis due to Candida sp].
Topics: Adult; Amphotericin B; Antifungal Agents; Candidiasis; Discitis; Fluconazole; Humans; Magnetic Reson | 2007 |
Postoperative Trichosporon asahii spondylodiscitis after open lumbar discectomy: a case report.
Topics: Adult; Antifungal Agents; Diagnosis, Differential; Discitis; Diskectomy; Female; Fluconazole; Humans | 2008 |
[Candida albicans spondylodiscitis. Treatment with fluconazole alone].
Topics: Adult; Candidiasis; Discitis; Female; Fluconazole; Humans | 1995 |
What is your neurologic diagnosis? An atypical case of diskspondylitis caused by Aspergillus spp.
Topics: Animals; Aspergillosis; Discitis; Dog Diseases; Dogs; Fatal Outcome; Female; Fluconazole; Lumbar Ver | 1995 |
Fluconazole therapy in Candida albicans spondylodiscitis.
Topics: Adult; Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis; Discitis; Drug Therapy, Com | 1998 |
[Aspergillus spondylodiscitis].
Topics: Adult; Amanita; Antifungal Agents; Aspergillosis; Discitis; Eye Infections, Fungal; Fluconazole; Hum | 2000 |