fluconazole has been researched along with Delayed Effects, Prenatal Exposure in 9 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " She took a 150-mg dose of fluconazole 2 weeks ago for the treatment of vaginal candidiasis and she is worried about the effect on her child and pregnancy." | 7.81 | Fluconazole exposure during pregnancy. ( Bozzo, P; Kaplan, YC; Koren, G, 2015) |
| "We evaluated pregnancy outcomes in 234 women exposed to fluconazole, 492 exposed to a topically administered azole preparation, 88 exposed to an oral azole preparation other than fluconazole, and 1629 not exposed to any of these agents during the first trimester of pregnancy Relative risks of having a baby with a congenital disorder for women exposed to fluconazole, oral azoles, and topical azoles in the first trimester of pregnancy compared with those who were unexposed were 1." | 7.70 | Pregnancy outcomes after maternal exposure to fluconazole. ( Jick, SS, 1999) |
| " The oral antifungal agents used during pregnancy were fluconazole and itraconazole." | 5.05 | Fetal outcomes after maternal exposure to oral antifungal agents during pregnancy: A systematic review and meta-analysis. ( Liu, D; Wu, L; Zhang, C; Zhang, L, 2020) |
| " She took a 150-mg dose of fluconazole 2 weeks ago for the treatment of vaginal candidiasis and she is worried about the effect on her child and pregnancy." | 3.81 | Fluconazole exposure during pregnancy. ( Bozzo, P; Kaplan, YC; Koren, G, 2015) |
| "We evaluated pregnancy outcomes in 234 women exposed to fluconazole, 492 exposed to a topically administered azole preparation, 88 exposed to an oral azole preparation other than fluconazole, and 1629 not exposed to any of these agents during the first trimester of pregnancy Relative risks of having a baby with a congenital disorder for women exposed to fluconazole, oral azoles, and topical azoles in the first trimester of pregnancy compared with those who were unexposed were 1." | 3.70 | Pregnancy outcomes after maternal exposure to fluconazole. ( Jick, SS, 1999) |
| " However, patients with this phenotype have been reported with a new dominant mutation at the FGFR2 locus as well as in the offspring of mothers taking the antifungal agent fluconazole during early pregnancy." | 3.70 | Evidence for digenic inheritance in some cases of Antley-Bixler syndrome? ( Adès, L; Baraitser, M; Das, D; DeLozier-Blanchet, C; Hindmarsh, P; Honour, JW; Kelly, T; Kumar, D; Malcolm, S; McKee, S; McKeehan, WL; Nelson, I; Reardon, W; Rumsby, G; Sillence, D; Smith, A; Winter, RM, 2000) |
| "Fluconazole is a triazole antifungal used to treat mycotic infections." | 1.33 | Prenatal exposure to fluconazole: an identifiable dysmorphic phenotype. ( Lopez-Rangel, E; Van Allen, MI, 2005) |
| "Fluconazole (FCZ) is a potent inhibitor of the cytochrome P450 (CYP)-mediated metabolism of the anti-epileptic agent phenytoin (PHT), a well-known human and animal teratogen." | 1.32 | Additional investigation on the potentiation of phenytoin teratogenicity by fluconazole. ( Angelucci, S; Bellati, U; Di Ilio, C; Giampietro, F; Moio, P; Tiboni, GM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, D | 1 |
| Zhang, C | 1 |
| Wu, L | 1 |
| Zhang, L | 2 |
| Mogensen, DM | 1 |
| Pihl, MB | 1 |
| Skakkebæk, NE | 1 |
| Andersen, HR | 1 |
| Juul, A | 1 |
| Kyhl, HB | 1 |
| Swan, S | 1 |
| Kristensen, DM | 1 |
| Andersen, MS | 1 |
| Lind, DV | 1 |
| Jensen, TK | 1 |
| Kaplan, YC | 1 |
| Koren, G | 1 |
| Bozzo, P | 1 |
| Barzin, A | 1 |
| Mounsey, A | 1 |
| Tiboni, GM | 1 |
| Giampietro, F | 1 |
| Angelucci, S | 1 |
| Moio, P | 1 |
| Bellati, U | 1 |
| Di Ilio, C | 1 |
| Lopez-Rangel, E | 1 |
| Van Allen, MI | 1 |
| Wray, CM | 1 |
| Jick, SS | 1 |
| Reardon, W | 1 |
| Smith, A | 1 |
| Honour, JW | 1 |
| Hindmarsh, P | 1 |
| Das, D | 1 |
| Rumsby, G | 1 |
| Nelson, I | 1 |
| Malcolm, S | 1 |
| Adès, L | 1 |
| Sillence, D | 1 |
| Kumar, D | 1 |
| DeLozier-Blanchet, C | 1 |
| McKee, S | 1 |
| Kelly, T | 1 |
| McKeehan, WL | 1 |
| Baraitser, M | 1 |
| Winter, RM | 1 |
1 review available for fluconazole and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Fetal outcomes after maternal exposure to oral antifungal agents during pregnancy: A systematic review and meta-analysis.
Topics: Abortion, Spontaneous; Antifungal Agents; Case-Control Studies; Cohort Studies; Congenital Abnormali | 2020 |
8 other studies available for fluconazole and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study.
Topics: Adult; Androgen Antagonists; Antifungal Agents; Denmark; Female; Fluconazole; Genitalia, Male; Human | 2017 |
Fluconazole exposure during pregnancy.
Topics: Abnormalities, Drug-Induced; Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Huma | 2015 |
PURLs: Yeast infection in pregnancy? Think twice about fluconazole.
Topics: Abortion, Spontaneous; Administration, Oral; Administration, Topical; Antifungal Agents; Azoles; Fem | 2016 |
Additional investigation on the potentiation of phenytoin teratogenicity by fluconazole.
Topics: Animals; Chromatography, High Pressure Liquid; Cleft Palate; Dose-Response Relationship, Drug; Drug | 2003 |
Prenatal exposure to fluconazole: an identifiable dysmorphic phenotype.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Antifungal Agents; Female; Fluconazole; HIV In | 2005 |
Congenital anomalies and fluconazole.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Antifungal Agents; Candidiasis, Vulvo | 1997 |
Pregnancy outcomes after maternal exposure to fluconazole.
Topics: Abnormalities, Drug-Induced; Antifungal Agents; Female; Fluconazole; Humans; Limb Deformities, Conge | 1999 |
Evidence for digenic inheritance in some cases of Antley-Bixler syndrome?
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Ankle Joint; Ankylosis; Craniosynostoses; Eye | 2000 |