fluconazole has been researched along with Cytomegalovirus Infections in 14 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Cytomegalovirus Infections: Infection with CYTOMEGALOVIRUS, characterized by enlarged cells bearing intranuclear inclusions. Infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Early studies suggest that a new acyclic nucleoside, ganciclovir, has some effect in the treatment of cytomegalovirus infections, but its precise use in patients with cancer has not been fully established." | 4.78 | New drugs for infections in patients with cancer. ( Hughes, WT, 1992) |
| "We describe a renal transplant recipient, with overimmunosuppression induced by the interaction of tacrolimus and fluconazole, who developed two severe diseases produced by two different viruses of the herpes group (cytomegalovirus [CMV] disease and posttransplant lymphoproliferative [PTLD] disease EBV-related)." | 3.71 | [Remission of severe disease induced by CMV and lymphoproliferative post-transplant disease after changing the immunosuppressive regime]. ( Alvarez Grande, J; de Oña, M; Fresno, MF; Gómez, E; Herreros, M; Melón, S; Navascués, R; Tricas, L, 2002) |
| " Advances in pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobial medications have led to improved dosing guidance for neonates." | 2.52 | New antifungal and antiviral dosing. ( Monk, HM; Wade, KC, 2015) |
| "A 56-year-old Japanese man with ulcerative colitis and a history of Sweet's syndrome who was taking prednisolone and azathioprine presented with a moderate exacerbation of ulcerative colitis, abdominal pain, diarrhea, and bloody stools along with cytomegalovirus infection." | 1.91 | Ulcerative colitis successfully treated with vedolizumab in the presence of comorbid opportunistic infections: a case report. ( Ichimori, T; Ishikawa, Y; Nagano, S; Oki, Y; Uchida, K; Yamada, T, 2023) |
| " Although there was a 40% increase in the volume of distribution for fluconazole relative to healthy volunteers, the pharmacodynamic targets for prophylaxis were still met." | 1.62 | Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO: a case report. ( Abdul-Aziz, MH; Dhanani, JA; Lipman, J; Livermore, A; Pincus, J; Roberts, JA; Townsend, S; Wallis, SC, 2021) |
| "There were 91 patients with acute myeloid leukemia (AML), 51 with acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL), and 68 with ATL." | 1.39 | Distinct clinical features of infectious complications in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation: a retrospective analysis in the Nagasaki transplant group. ( Ando, K; Fukushima, T; Hata, T; Honda, S; Imaizumi, Y; Imanishi, D; Itonaga, H; Matsuo, E; Miyazaki, Y; Moriuchi, Y; Onimaru, Y; Sato, S; Sawayama, Y; Taguchi, J; Tsushima, H; Yamasaki, R; Yoshida, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Dhanani, JA | 1 |
| Lipman, J | 1 |
| Pincus, J | 1 |
| Townsend, S | 1 |
| Livermore, A | 1 |
| Wallis, SC | 1 |
| Abdul-Aziz, MH | 1 |
| Roberts, JA | 1 |
| Oki, Y | 1 |
| Nagano, S | 1 |
| Ishikawa, Y | 1 |
| Yamada, T | 1 |
| Ichimori, T | 1 |
| Uchida, K | 1 |
| Giménez, E | 1 |
| Solano, C | 1 |
| Nieto, J | 1 |
| Remigia, MJ | 1 |
| Clari, MÁ | 1 |
| Costa, E | 1 |
| Muñoz-Cobo, B | 1 |
| Amat, P | 1 |
| Bravo, D | 1 |
| Benet, I | 1 |
| Navarro, D | 1 |
| Wade, KC | 1 |
| Monk, HM | 1 |
| Itonaga, H | 1 |
| Taguchi, J | 1 |
| Fukushima, T | 1 |
| Tsushima, H | 1 |
| Sato, S | 1 |
| Ando, K | 1 |
| Sawayama, Y | 1 |
| Matsuo, E | 1 |
| Yamasaki, R | 1 |
| Onimaru, Y | 1 |
| Imanishi, D | 1 |
| Imaizumi, Y | 1 |
| Yoshida, S | 1 |
| Hata, T | 1 |
| Moriuchi, Y | 1 |
| Honda, S | 1 |
| Miyazaki, Y | 1 |
| Paya, CV | 1 |
| Gómez, E | 1 |
| Melón, S | 1 |
| Fresno, MF | 1 |
| Tricas, L | 1 |
| Navascués, R | 1 |
| de Oña, M | 1 |
| Herreros, M | 1 |
| Alvarez Grande, J | 1 |
| Tascini, C | 1 |
| Ferranti, S | 1 |
| Leonildi, A | 1 |
| Menichetti, F | 1 |
| Maslo, C | 1 |
| Peraldi, MN | 1 |
| Desenclos, JC | 1 |
| Mougenot, B | 1 |
| Cywiner-Golenzer, C | 1 |
| Chatelet, FP | 1 |
| Jacomet, C | 1 |
| Rondeau, E | 1 |
| Rozenbaum, W | 1 |
| Sraer, JD | 1 |
| Peggs, KS | 1 |
| Preiser, W | 1 |
| Kottaridis, PD | 1 |
| McKeag, N | 1 |
| Brink, NS | 1 |
| Tedder, RS | 1 |
| Goldstone, AH | 1 |
| Linch, DC | 1 |
| Mackinnon, S | 1 |
| Cheng, B | 1 |
| Glick, ME | 1 |
| Hughes, WT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole and Dapsone and Their Hydroxylamine Metabolites[NCT00000826] | Phase 1 | 48 participants | Interventional | Completed | |||
| A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected Children[NCT00000637] | Phase 3 | 819 participants | Interventional | Completed | |||
| Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)[NCT00000676] | Phase 3 | 500 participants | Interventional | Completed | |||
| A Randomized Trial of Three Anti-Pneumocystis Agents Plus Zidovudine for the Primary Prevention of Serious Infections in Patients With Advanced HIV Infection[NCT00000991] | Phase 3 | 600 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for fluconazole and Cytomegalovirus Infections
| Article | Year |
|---|---|
New antifungal and antiviral dosing.
Topics: Acyclovir; Amphotericin B; Antifungal Agents; Antiviral Agents; Candidiasis, Invasive; Cytomegalovir | 2015 |
Prevention of fungal infection in transplantation.
Topics: Amphotericin B; Antifungal Agents; Basement Membrane; Candida; Candidiasis; Cytomegalovirus Infectio | 2002 |
New drugs for infections in patients with cancer.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Bacterial Infections; Cytomegalovirus Infections; Fluc | 1992 |
11 other studies available for fluconazole and Cytomegalovirus Infections
| Article | Year |
|---|---|
Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO: a case report.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antifungal Agents; Antiviral Agents; Candida albicans; Ca | 2021 |
Ulcerative colitis successfully treated with vedolizumab in the presence of comorbid opportunistic infections: a case report.
Topics: Colitis, Ulcerative; Cytomegalovirus Infections; Fluconazole; Humans; Inflammatory Bowel Diseases; M | 2023 |
An investigation on the relationship between the occurrence of CMV DNAemia and the development of invasive aspergillosis in the allogeneic stem cell transplantation setting.
Topics: Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Aspergillus; Cytomegalovirus; Cytomegalo | 2014 |
Distinct clinical features of infectious complications in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation: a retrospective analysis in the Nagasaki transplant group.
Topics: Adolescent; Adult; Aged; Antifungal Agents; Bacterial Infections; Cytomegalovirus Infections; Female | 2013 |
[Remission of severe disease induced by CMV and lymphoproliferative post-transplant disease after changing the immunosuppressive regime].
Topics: Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Epstein-Barr Virus Infections; Flucon | 2002 |
Breakthrough Fusarium sp probable pneumonia during fluconazole therapy in an AIDS patient with diabetes, candidemia, Pneumocystis carinii pneumonia and cytomegalovirus disseminated infection.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis; Cytomegalovirus Infections; D | 2006 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifunga | 1995 |
Thrombotic microangiopathy and cytomegalovirus disease in patients infected with human immunodeficiency virus.
Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Bronchi; Case-Control Studies; Cyto | 1997 |
Extended routine polymerase chain reaction surveillance and pre-emptive antiviral therapy for cytomegalovirus after allogeneic transplantation.
Topics: Acyclovir; Adolescent; Adult; Antifungal Agents; Antiviral Agents; Bone Marrow Transplantation; Cycl | 2000 |
Preventing opportunistic infections.
Topics: Acyclovir; AIDS-Related Opportunistic Infections; Clarithromycin; Clindamycin; Clinical Trials as To | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |
CTG studies yield results. AIDS Clinical Trials Group.
Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co | 1995 |