Page last updated: 2024-10-27

fluconazole and Cytomegalovirus Infections

fluconazole has been researched along with Cytomegalovirus Infections in 14 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Cytomegalovirus Infections: Infection with CYTOMEGALOVIRUS, characterized by enlarged cells bearing intranuclear inclusions. Infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults.

Research Excerpts

ExcerptRelevanceReference
" Early studies suggest that a new acyclic nucleoside, ganciclovir, has some effect in the treatment of cytomegalovirus infections, but its precise use in patients with cancer has not been fully established."4.78New drugs for infections in patients with cancer. ( Hughes, WT, 1992)
"We describe a renal transplant recipient, with overimmunosuppression induced by the interaction of tacrolimus and fluconazole, who developed two severe diseases produced by two different viruses of the herpes group (cytomegalovirus [CMV] disease and posttransplant lymphoproliferative [PTLD] disease EBV-related)."3.71[Remission of severe disease induced by CMV and lymphoproliferative post-transplant disease after changing the immunosuppressive regime]. ( Alvarez Grande, J; de Oña, M; Fresno, MF; Gómez, E; Herreros, M; Melón, S; Navascués, R; Tricas, L, 2002)
" Advances in pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobial medications have led to improved dosing guidance for neonates."2.52New antifungal and antiviral dosing. ( Monk, HM; Wade, KC, 2015)
"A 56-year-old Japanese man with ulcerative colitis and a history of Sweet's syndrome who was taking prednisolone and azathioprine presented with a moderate exacerbation of ulcerative colitis, abdominal pain, diarrhea, and bloody stools along with cytomegalovirus infection."1.91Ulcerative colitis successfully treated with vedolizumab in the presence of comorbid opportunistic infections: a case report. ( Ichimori, T; Ishikawa, Y; Nagano, S; Oki, Y; Uchida, K; Yamada, T, 2023)
" Although there was a 40% increase in the volume of distribution for fluconazole relative to healthy volunteers, the pharmacodynamic targets for prophylaxis were still met."1.62Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO: a case report. ( Abdul-Aziz, MH; Dhanani, JA; Lipman, J; Livermore, A; Pincus, J; Roberts, JA; Townsend, S; Wallis, SC, 2021)
"There were 91 patients with acute myeloid leukemia (AML), 51 with acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL), and 68 with ATL."1.39Distinct clinical features of infectious complications in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation: a retrospective analysis in the Nagasaki transplant group. ( Ando, K; Fukushima, T; Hata, T; Honda, S; Imaizumi, Y; Imanishi, D; Itonaga, H; Matsuo, E; Miyazaki, Y; Moriuchi, Y; Onimaru, Y; Sato, S; Sawayama, Y; Taguchi, J; Tsushima, H; Yamasaki, R; Yoshida, S, 2013)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (35.71)18.2507
2000's4 (28.57)29.6817
2010's3 (21.43)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Dhanani, JA1
Lipman, J1
Pincus, J1
Townsend, S1
Livermore, A1
Wallis, SC1
Abdul-Aziz, MH1
Roberts, JA1
Oki, Y1
Nagano, S1
Ishikawa, Y1
Yamada, T1
Ichimori, T1
Uchida, K1
Giménez, E1
Solano, C1
Nieto, J1
Remigia, MJ1
Clari, MÁ1
Costa, E1
Muñoz-Cobo, B1
Amat, P1
Bravo, D1
Benet, I1
Navarro, D1
Wade, KC1
Monk, HM1
Itonaga, H1
Taguchi, J1
Fukushima, T1
Tsushima, H1
Sato, S1
Ando, K1
Sawayama, Y1
Matsuo, E1
Yamasaki, R1
Onimaru, Y1
Imanishi, D1
Imaizumi, Y1
Yoshida, S1
Hata, T1
Moriuchi, Y1
Honda, S1
Miyazaki, Y1
Paya, CV1
Gómez, E1
Melón, S1
Fresno, MF1
Tricas, L1
Navascués, R1
de Oña, M1
Herreros, M1
Alvarez Grande, J1
Tascini, C1
Ferranti, S1
Leonildi, A1
Menichetti, F1
Maslo, C1
Peraldi, MN1
Desenclos, JC1
Mougenot, B1
Cywiner-Golenzer, C1
Chatelet, FP1
Jacomet, C1
Rondeau, E1
Rozenbaum, W1
Sraer, JD1
Peggs, KS1
Preiser, W1
Kottaridis, PD1
McKeag, N1
Brink, NS1
Tedder, RS1
Goldstone, AH1
Linch, DC1
Mackinnon, S1
Cheng, B1
Glick, ME1
Hughes, WT1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole and Dapsone and Their Hydroxylamine Metabolites[NCT00000826]Phase 148 participants InterventionalCompleted
A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected Children[NCT00000637]Phase 3819 participants InterventionalCompleted
Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)[NCT00000676]Phase 3500 participants InterventionalCompleted
A Randomized Trial of Three Anti-Pneumocystis Agents Plus Zidovudine for the Primary Prevention of Serious Infections in Patients With Advanced HIV Infection[NCT00000991]Phase 3600 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for fluconazole and Cytomegalovirus Infections

ArticleYear
New antifungal and antiviral dosing.
    Clinics in perinatology, 2015, Volume: 42, Issue:1

    Topics: Acyclovir; Amphotericin B; Antifungal Agents; Antiviral Agents; Candidiasis, Invasive; Cytomegalovir

2015
Prevention of fungal infection in transplantation.
    Transplant infectious disease : an official journal of the Transplantation Society, 2002, Volume: 4 Suppl 3

    Topics: Amphotericin B; Antifungal Agents; Basement Membrane; Candida; Candidiasis; Cytomegalovirus Infectio

2002
New drugs for infections in patients with cancer.
    Cancer, 1992, Aug-15, Volume: 70, Issue:4 Suppl

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; Bacterial Infections; Cytomegalovirus Infections; Fluc

1992

Other Studies

11 other studies available for fluconazole and Cytomegalovirus Infections

ArticleYear
Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO: a case report.
    International journal of antimicrobial agents, 2021, Volume: 58, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antifungal Agents; Antiviral Agents; Candida albicans; Ca

2021
Ulcerative colitis successfully treated with vedolizumab in the presence of comorbid opportunistic infections: a case report.
    Journal of medical case reports, 2023, May-31, Volume: 17, Issue:1

    Topics: Colitis, Ulcerative; Cytomegalovirus Infections; Fluconazole; Humans; Inflammatory Bowel Diseases; M

2023
An investigation on the relationship between the occurrence of CMV DNAemia and the development of invasive aspergillosis in the allogeneic stem cell transplantation setting.
    Journal of medical virology, 2014, Volume: 86, Issue:4

    Topics: Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Aspergillus; Cytomegalovirus; Cytomegalo

2014
Distinct clinical features of infectious complications in adult T cell leukemia/lymphoma patients after allogeneic hematopoietic stem cell transplantation: a retrospective analysis in the Nagasaki transplant group.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Bacterial Infections; Cytomegalovirus Infections; Female

2013
[Remission of severe disease induced by CMV and lymphoproliferative post-transplant disease after changing the immunosuppressive regime].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2002, Volume: 22, Issue:6

    Topics: Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Epstein-Barr Virus Infections; Flucon

2002
Breakthrough Fusarium sp probable pneumonia during fluconazole therapy in an AIDS patient with diabetes, candidemia, Pneumocystis carinii pneumonia and cytomegalovirus disseminated infection.
    Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis; Cytomegalovirus Infections; D

2006
Drugs for AIDS and associated infections.
    The Medical letter on drugs and therapeutics, 1995, Oct-13, Volume: 37, Issue:959

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifunga

1995
Thrombotic microangiopathy and cytomegalovirus disease in patients infected with human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Bronchi; Case-Control Studies; Cyto

1997
Extended routine polymerase chain reaction surveillance and pre-emptive antiviral therapy for cytomegalovirus after allogeneic transplantation.
    British journal of haematology, 2000, Volume: 111, Issue:3

    Topics: Acyclovir; Adolescent; Adult; Antifungal Agents; Antiviral Agents; Bone Marrow Transplantation; Cycl

2000
Preventing opportunistic infections.
    PI perspective, 1995, Issue:no 16

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Clarithromycin; Clindamycin; Clinical Trials as To

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995
CTG studies yield results. AIDS Clinical Trials Group.
    NIAID AIDS agenda, 1995,Spring

    Topics: Acyclovir; Child; Clinical Trials as Topic; Cytomegalovirus Infections; Didanosine; Drug Therapy, Co

1995