Page last updated: 2024-10-27

fluconazole and Cystic Fibrosis

fluconazole has been researched along with Cystic Fibrosis in 7 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
" The patient in this case responded to isavuconazole treatment for breakthrough infection due to B raffinosifermentans that was cultured from pleural fluid while on posaconazole prophylaxis post-bilateral lung transplantation for cystic fibrosis."5.12Pulmonary infection secondary to Blastobotrys raffinosifermentans in a cystic fibrosis patient: Review of the literature. ( Al-Obaidi, M; Badali, H; Cañete-Gibas, C; Patterson, HP; Wiederhold, NP, 2021)
"Invasive candidiasis is rare in children after the neonatal period, but can occur in children with (secondary) immunodeficiency with a damaged gastrointestinal or skin barrier, or when receiving antibiotics."1.37Osteoarticular infection by Candida albicans in an infant with cystic fibrosis. ( Abele-Horn, M; Beer, M; Hebestreit, H; Kunzmann, S; Radike, K, 2011)
"Fluticasone was discontinued, and the patient's adrenal function normalized."1.37Rapid onset of iatrogenic adrenal insufficiency in a patient with cystic fibrosis-related liver disease treated with inhaled corticosteroids and a moderate CYP3A4 inhibitor. ( Britton, LJ; Gardner, J; Gutierrez, H; Hoover, WC; Jackson, T, 2011)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Lepesqueur, LSS1
Tanaka, MH1
Lima, GMG1
Chiba, SM1
Mota, AJ1
Santos, SF1
Koga-Ito, CY1
Al-Obaidi, M1
Badali, H1
Cañete-Gibas, C1
Patterson, HP1
Wiederhold, NP1
Demers, EG1
Biermann, AR1
Masonjones, S1
Crocker, AW1
Ashare, A1
Stajich, JE1
Hogan, DA1
Radike, K1
Kunzmann, S1
Abele-Horn, M1
Beer, M1
Hebestreit, H1
Hoover, WC1
Britton, LJ1
Gardner, J1
Jackson, T1
Gutierrez, H1
Gammelsrud, KW1
Lindstad, BL1
Gaustad, P1
Ingebretsen, A1
Høiby, EA1
Brandtzaeg, P1
Sandven, P1
Levy, PY1
Habib, G1
Reynaud-Gaubert, M1
Raoult, D1
Rolain, JM1

Reviews

1 review available for fluconazole and Cystic Fibrosis

ArticleYear
Pulmonary infection secondary to Blastobotrys raffinosifermentans in a cystic fibrosis patient: Review of the literature.
    Mycoses, 2021, Volume: 64, Issue:6

    Topics: Adult; Amphotericin B; Antifungal Agents; Cystic Fibrosis; Female; Fluconazole; Genes, Fungal; Human

2021

Other Studies

6 other studies available for fluconazole and Cystic Fibrosis

ArticleYear
Oral prevalence and antifungal susceptibility of Candida species in cystic fibrosis patients.
    Archives of oral biology, 2020, Volume: 116

    Topics: Adolescent; Antifungal Agents; Candida; Child; Child, Preschool; Cystic Fibrosis; Drug Resistance, F

2020
Evolution of drug resistance in an antifungal-naive chronic
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 11-20, Volume: 115, Issue:47

    Topics: Alleles; Antifungal Agents; Candida; Candidiasis; Chronic Disease; Cystic Fibrosis; Drug Resistance,

2018
Osteoarticular infection by Candida albicans in an infant with cystic fibrosis.
    Journal of medical microbiology, 2011, Volume: 60, Issue:Pt 10

    Topics: Amphotericin B; Antifungal Agents; Candida albicans; Candidemia; Candidiasis, Invasive; Cystic Fibro

2011
Rapid onset of iatrogenic adrenal insufficiency in a patient with cystic fibrosis-related liver disease treated with inhaled corticosteroids and a moderate CYP3A4 inhibitor.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:7-8

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenal Insufficiency; Androstadienes; Anti-Ast

2011
Multilocus sequence typing of serial Candida albicans isolates from children with cancer, children with cystic fibrosis and healthy controls.
    Medical mycology, 2012, Volume: 50, Issue:6

    Topics: Adenoids; Adolescent; Antifungal Agents; Candida albicans; Candidiasis; Case-Control Studies; Child;

2012
Pericardial effusion due to Cryptococcus neoformans in a patient with cystic fibrosis following lung transplantation.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2008, Volume: 12, Issue:4

    Topics: Adult; Antifungal Agents; Cardiac Tamponade; Cryptococcosis; Cryptococcus neoformans; Cystic Fibrosi

2008