fluconazole has been researched along with Cushing Syndrome in 3 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Cushing Syndrome: A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of fluconazole as an alternative treatment for controlling hypercortisolism in Cushing's syndrome and to determine its effect on glucocorticoid production in vitro." | 3.73 | Long term control of hypercortisolism with fluconazole: case report and in vitro studies. ( Luger, A; Maier, C; Nowotny, P; Riedl, M; Schima, W; Zettinig, G, 2006) |
| "Fluconazole is an alternative treatment especially in Cushing's disease patients with cryptococcal pneumonia." | 1.56 | Fluconazole for Hypercortisolism in Cushing's Disease: A Case Report and Literature Review. ( Cai, F; Liang, W; Wang, Y; Wu, Q; Zhao, Y, 2020) |
| "Fluticasone was discontinued, and the patient's adrenal function normalized." | 1.37 | Rapid onset of iatrogenic adrenal insufficiency in a patient with cystic fibrosis-related liver disease treated with inhaled corticosteroids and a moderate CYP3A4 inhibitor. ( Britton, LJ; Gardner, J; Gutierrez, H; Hoover, WC; Jackson, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Y | 1 |
| Liang, W | 1 |
| Cai, F | 1 |
| Wu, Q | 1 |
| Wang, Y | 1 |
| Hoover, WC | 1 |
| Britton, LJ | 1 |
| Gardner, J | 1 |
| Jackson, T | 1 |
| Gutierrez, H | 1 |
| Riedl, M | 1 |
| Maier, C | 1 |
| Zettinig, G | 1 |
| Nowotny, P | 1 |
| Schima, W | 1 |
| Luger, A | 1 |
3 other studies available for fluconazole and Cushing Syndrome
| Article | Year |
|---|---|
Fluconazole for Hypercortisolism in Cushing's Disease: A Case Report and Literature Review.
Topics: Antifungal Agents; Brain; Cryptococcosis; Cryptococcus neoformans; Cushing Syndrome; Female; Flucona | 2020 |
Rapid onset of iatrogenic adrenal insufficiency in a patient with cystic fibrosis-related liver disease treated with inhaled corticosteroids and a moderate CYP3A4 inhibitor.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenal Insufficiency; Androstadienes; Anti-Ast | 2011 |
Long term control of hypercortisolism with fluconazole: case report and in vitro studies.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aged, 80 and over; Antifungal Agents; Cell Line, Tu | 2006 |