Page last updated: 2024-10-27

fluconazole and Craniofacial Abnormalities

fluconazole has been researched along with Craniofacial Abnormalities in 2 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Craniofacial Abnormalities: Congenital structural deformities, malformations, or other abnormalities of the cranium and facial bones.

Research Excerpts

ExcerptRelevanceReference
"Oral fluconazole is used to treat vulvovaginal candidiasis during pregnancy."9.01The safety of oral fluconazole during the first trimester of pregnancy: a systematic review and meta-analysis. ( Jiang, CM; Jiang, HY; Zhang, X; Zhang, Z; Zhou, YY, 2019)
"Oral fluconazole is used to treat vulvovaginal candidiasis during pregnancy."5.01The safety of oral fluconazole during the first trimester of pregnancy: a systematic review and meta-analysis. ( Jiang, CM; Jiang, HY; Zhang, X; Zhang, Z; Zhou, YY, 2019)
" Because half of all pregnancies are unplanned and pregnant women have an increased risk of VVC recurrence, the likelihood of inadvertently being exposed to fluconazole in pregnancy is increased."4.91Exposure to fluconazole and risk of congenital malformations in the offspring: A systematic review and meta-analysis. ( Alsaad, AM; Kaplan, YC; Koren, G, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, Z1
Zhang, X1
Zhou, YY1
Jiang, CM1
Jiang, HY1
Alsaad, AM1
Kaplan, YC1
Koren, G1

Reviews

2 reviews available for fluconazole and Craniofacial Abnormalities

ArticleYear
The safety of oral fluconazole during the first trimester of pregnancy: a systematic review and meta-analysis.
    BJOG : an international journal of obstetrics and gynaecology, 2019, Volume: 126, Issue:13

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Antifungal Agents; Candidiasis, Vulvovaginal; Cra

2019
Exposure to fluconazole and risk of congenital malformations in the offspring: A systematic review and meta-analysis.
    Reproductive toxicology (Elmsford, N.Y.), 2015, Volume: 52

    Topics: Abnormalities, Drug-Induced; Antifungal Agents; Candidiasis, Vulvovaginal; Craniofacial Abnormalitie

2015