fluconazole has been researched along with Chromosomal Triplication in 2 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We established that Chr4 trisomy contributes significantly to fluconazole resistance, whereas Chr6 trisomy has no discernible effect on resistance." | 1.46 | A chromosome 4 trisomy contributes to increased fluconazole resistance in a clinical isolate of Candida albicans. ( Anderson, MZ; Bennett, RJ; Haseeb, A; Saha, A, 2017) |
| "We found that aneuploidy in general and a specific segmental aneuploidy, consisting of an isochromosome composed of the two left arms of chromosome 5, were associated with azole resistance." | 1.33 | Aneuploidy and isochromosome formation in drug-resistant Candida albicans. ( Berman, J; Forche, A; Selmecki, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, MZ | 1 |
| Saha, A | 1 |
| Haseeb, A | 1 |
| Bennett, RJ | 1 |
| Selmecki, A | 1 |
| Forche, A | 1 |
| Berman, J | 1 |
2 other studies available for fluconazole and Chromosomal Triplication
| Article | Year |
|---|---|
A chromosome 4 trisomy contributes to increased fluconazole resistance in a clinical isolate of Candida albicans.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Chromosomes, Fungal; Drug Resistance, Fungal; Fluc | 2017 |
Aneuploidy and isochromosome formation in drug-resistant Candida albicans.
Topics: Aneuploidy; Antifungal Agents; Azoles; Candida albicans; Centromere; Chromosomes, Fungal; Cytochrome | 2006 |