fluconazole has been researched along with Chagas Disease in 6 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have previously shown that 3-nitro-1H-1,2,4-triazole-based arylamides and arylsulfonamides demonstrate significant activity in vitro against Trypanosoma cruzi, the causative parasite of Chagas disease." | 3.80 | Novel nitro(triazole/imidazole)-based heteroarylamides/sulfonamides as potential antitrypanosomal agents. ( Bloomer, WD; Kaiser, M; Papadopoulou, MV; Rosenzweig, HS; Wilkinson, SR, 2014) |
| "Persons with hemophilia who receive multiple blood product transfusions from blood banks with little or no screening for infectious agents are at particularly high risk for infections with both HIV and T." | 1.29 | Successful treatment of Trypanosoma cruzi encephalitis in a patient with hemophilia and AIDS. ( Acuña, G; Brengues, C; Cuny, G; Labarca, J; Muñoz, S; Oddó, D; Saavedra, H; Sepúlveda, C; Solari, A; Veas, F, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Papadopoulou, MV | 2 |
| Bloomer, WD | 2 |
| Rosenzweig, HS | 2 |
| Wilkinson, SR | 2 |
| Kaiser, M | 2 |
| Lepesheva, GI | 1 |
| Aguilera-Venegas, B | 1 |
| Chatelain, E | 1 |
| Ioset, JR | 1 |
| Ferreira de Almeida Fiuza, L | 1 |
| Peres, RB | 1 |
| Simões-Silva, MR | 1 |
| da Silva, PB | 1 |
| Batista, DDGJ | 1 |
| da Silva, CF | 1 |
| Nefertiti Silva da Gama, A | 1 |
| Krishna Reddy, TR | 1 |
| Soeiro, MNC | 1 |
| de Azevedo-França, JA | 1 |
| Barrias, E | 1 |
| Franco, CHJ | 1 |
| Villarreal, W | 1 |
| Vieira, EG | 1 |
| Ferreira, AMDC | 1 |
| de Souza, W | 1 |
| Navarro, M | 1 |
| Peron, F | 1 |
| Lazarin-Bidóia, D | 1 |
| Ud Din, Z | 1 |
| Rodrigues-Filho, E | 1 |
| Ueda-Nakamura, T | 1 |
| Silva, SO | 1 |
| Nakamura, CV | 1 |
| Solari, A | 1 |
| Saavedra, H | 1 |
| Sepúlveda, C | 1 |
| Oddó, D | 1 |
| Acuña, G | 1 |
| Labarca, J | 1 |
| Muñoz, S | 1 |
| Cuny, G | 1 |
| Brengues, C | 1 |
| Veas, F | 1 |
6 other studies available for fluconazole and Chagas Disease
| Article | Year |
|---|---|
Novel nitro(triazole/imidazole)-based heteroarylamides/sulfonamides as potential antitrypanosomal agents.
Topics: Amides; Apoptosis; Blood Platelets; Cells, Cultured; Chagas Disease; Flow Cytometry; Heterocyclic Co | 2014 |
Novel 3-nitrotriazole-based amides and carbinols as bifunctional antichagasic agents.
Topics: Amides; Animals; Cell Line; Chagas Disease; Dose-Response Relationship, Drug; Methanol; Mice; Mice, | 2015 |
Identification of Pyrazolo[3,4-e][1,4]thiazepin based CYP51 inhibitors as potential Chagas disease therapeutic alternative: In vitro and in vivo evaluation, binding mode prediction and SAR exploration.
Topics: 14-alpha Demethylase Inhibitors; Animals; Chagas Disease; Mice; Molecular Docking Simulation; Parasi | 2018 |
Promising fluconazole based zinc(II) and copper(II) coordination polymers against Chagas disease.
Topics: Chagas Disease; Coordination Complexes; Copper; Crystallography, X-Ray; Fluconazole; Humans; Polymer | 2022 |
Effects of (1
Topics: Chagas Disease; Drug Combinations; Drug Synergism; Fluconazole; Humans; Ketoconazole; Nitroimidazole | 2017 |
Successful treatment of Trypanosoma cruzi encephalitis in a patient with hemophilia and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Chagas Disease; Dr | 1993 |