Page last updated: 2024-10-27

fluconazole and Cerebromeningitis

fluconazole has been researched along with Cerebromeningitis in 28 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Research Excerpts

ExcerptRelevanceReference
"The combined infection of Actinomyces odontolyticus sepsis and cryptococcal encephalitis is first reported in this case report, and combined antibiotics with 'penicillin, amphotericin, and fluconazole' are effective."5.41Cryptococcal meningoencephalitis with Actinomyces odontolyticus sepsis: a case report and literature review. ( Hong, Q; Hong, Z; Huang, Q, 2023)
"Miltefosine treatment (1."5.39Limited activity of miltefosine in murine models of cryptococcal meningoencephalitis and disseminated cryptococcosis. ( Bocanegra, R; Kirkpatrick, WR; Najvar, LK; Patterson, TF; Sorrell, TC; Wiederhold, NP, 2013)
"Balamuthia mandrillaris meningoencephalitis is a rare but often fatal infection; only 2 survivors have been reported to date worldwide."2.42Balamuthia mandrillaris meningoencephalitis in an immunocompetent patient: an unusual clinical course and a favorable outcome. ( Chang, HT; Jung, S; Schelper, RL; Visvesvara, GS, 2004)
" The objective of the study was to investigate the efficacy of acetazolamide (AZA), candesartan (CAN), and triciribine (TCBN), in combination with the antifungal fluconazole, on C."1.91A multi-arm, parallel, preclinical study investigating the potential benefits of acetazolamide, candesartan, and triciribine in combination with fluconazole for the treatment of cryptococcal meningoencephalitis. ( Alanazi, AH; Chastain, DB; Franco-Paredes, C; Henao-Martínez, AF; Lin, X; Narayanan, SP; Parvathagiri, V; Rudraraju, M; Shan, S; Somanath, PR, 2023)
"Cryptococcal meningitis is an opportunistic infection predominantly affecting immunocompromised patients but rarely can affect the immunocompetent."1.51Rare presentation of cryptococcal meningitis in an immunocompetent patient. ( Khattab, A; Patruni, S; Sealey, ML, 2019)
" The dosage was increased (800 mg/day) following laboratory diagnosis of C."1.40Cryptococcus neoformans meningoencephalitis in a patient with polyarteritis nodosa. ( Buchta, V; Drahošová, M; Kutová, R; Mottl, R; Plíšek, S; Prášil, P; Vejsová, M, 2014)
" Fluconazole may be an inferior agent for induction therapy because many patients cannot achieve the pharmacodynamic target."1.39Pharmacokinetics and pharmacodynamics of fluconazole for cryptococcal meningoencephalitis: implications for antifungal therapy and in vitro susceptibility breakpoints. ( Al-Nakeeb, Z; Felton, TW; Goodwin, J; Gregson, L; Harrison, TS; Hope, WW; Howard, SJ; Livermore, J; Perfect, JR; Sharp, A; Sudan, A; Warn, PA, 2013)
"In contrast, aneuploidy can also be advantageous and in fungi confers antifungal drug resistance and enables rapid adaptive evolution."1.39Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans. ( Dietrich, FS; Feretzaki, M; Floyd-Averette, A; Heitman, J; Li, W; Mieczkowski, P; Ni, M, 2013)
"Miltefosine treatment (1."1.39Limited activity of miltefosine in murine models of cryptococcal meningoencephalitis and disseminated cryptococcosis. ( Bocanegra, R; Kirkpatrick, WR; Najvar, LK; Patterson, TF; Sorrell, TC; Wiederhold, NP, 2013)
"For treatment, fluconazole or posaconazole (10 mg/kg orally twice daily) was initiated 24 h post-inoculation."1.38A murine model of Cryptococcus gattii meningoencephalitis. ( Bocanegra, R; Graybill, JR; Kirkpatrick, WR; Najvar, LK; Patterson, TF; Thompson, GR; Wiederhold, NP, 2012)
"Zygomycosis is an infection caused by opportunistic fungi of the Zygomycetes class, specifically those from the Mucorales and Entomophthorales orders."1.36Meningoencephalitis caused by a zygomycete fungus (Basidiobolus) associated with septic shock in an immunocompetent patient: 1-year follow-up after treatment. ( Alkmim-Teixeira, GC; Auxiliadora-Martins, M; Basile-Filho, A; Bellissimo-Rodrigues, F; Carlotti, CG; Machado-Viana, J; Martins-Filho, OA; Nicolini, EA, 2010)
"A cryptococcus neoformans septicemia with meningoencephalitis was diagnosed."1.30Cryptococcosis, epileptic seizures and encephalopathy in a HIV-infected patient. ( Elzi, M; Reusser, P; Tolnay, M, 1997)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (21.43)18.2507
2000's6 (21.43)29.6817
2010's11 (39.29)24.3611
2020's5 (17.86)2.80

Authors

AuthorsStudies
Huang, Q1
Hong, Z1
Hong, Q1
Giamberardino, CD1
Tenor, JL1
Toffaletti, DL1
Palmucci, JR1
Schell, W1
Boua, J-VK1
Marius, C1
Stott, KE2
Steele, SL1
Hope, W2
Cilla, D1
Perfect, JR3
Alanazi, AH1
Chastain, DB1
Rudraraju, M1
Parvathagiri, V1
Shan, S1
Lin, X1
Henao-Martínez, AF1
Franco-Paredes, C1
Narayanan, SP1
Somanath, PR1
Anjum, S1
Dean, O1
Kosa, P1
Magone, MT1
King, KA1
Fitzgibbon, E1
Kim, HJ1
Zalewski, C1
Murphy, E1
Billioux, BJ1
Chisholm, J1
Brewer, CC1
Krieger, C1
Elsegeiny, W1
Scott, TL1
Wang, J1
Hunsberger, S1
Bennett, JE1
Nath, A1
Marr, KA1
Bielekova, B1
Wendler, D1
Hammoud, DA1
Williamson, P1
Loyse, A1
Jarvis, JN1
Alufandika, M1
Harrison, TS2
Mwandumba, HC1
Day, JN1
Lalloo, DG1
Bicanic, T1
Khattab, A1
Patruni, S1
Sealey, ML1
Sudan, A1
Livermore, J1
Howard, SJ1
Al-Nakeeb, Z1
Sharp, A1
Goodwin, J1
Gregson, L1
Warn, PA1
Felton, TW1
Hope, WW1
Ni, M1
Feretzaki, M1
Li, W1
Floyd-Averette, A1
Mieczkowski, P1
Dietrich, FS1
Heitman, J1
Buchta, V1
Prášil, P1
Vejsová, M1
Mottl, R1
Kutová, R1
Drahošová, M1
Plíšek, S1
Dunn, AL1
Reed, T1
Stewart, C1
Levy, RA1
Stanga, SD1
Dajud, MV1
Georgi, A1
Schneemann, M1
Tintelnot, K1
Calligaris-Maibach, RC1
Meyer, S1
Weber, R1
Bosshard, PP1
Persad, P1
Patel, R1
Stephens, J1
Francis-Rogers, S1
Talat, P1
Auxiliadora-Martins, M1
Alkmim-Teixeira, GC1
Machado-Viana, J1
Nicolini, EA1
Martins-Filho, OA1
Bellissimo-Rodrigues, F1
Carlotti, CG1
Basile-Filho, A1
Shoji, H1
Takuma, T1
Ohbayashi, H1
Yoshida, K1
Yamamoto, T1
Niki, Y1
Thompson, GR1
Wiederhold, NP2
Najvar, LK2
Bocanegra, R2
Kirkpatrick, WR2
Graybill, JR1
Patterson, TF2
Zak, I1
Jagielski, T1
Kwiatkowski, S1
Bielecki, J1
Sorrell, TC1
Jung, S1
Schelper, RL1
Visvesvara, GS1
Chang, HT1
Nakata, M1
Ito, S1
Kikkawa, Y1
Katayama, K1
Yang, CC1
Lee, HS1
Chen, CC1
Cheng, CJ1
Lin, SH1
Sivasangeetha, K1
Harish, BN1
Sujatha, S1
Parija, SC1
Dutta, TK1
Nakamura, K1
Tanaka, Y1
Oita, J1
Yamaguchi, T1
Donabedian, H1
O'Donnell, E1
Olszewski, C1
MacArthur, RD1
Budd, N1
Lindsberg, PJ1
Pieninkeroinen, I1
Valtonen, M1
Tolnay, M1
Elzi, M1
Reusser, P1
Suzuki, Y1
Onodera, J1
Sakuma, R1
Shiga, Y1
Fujihara, K1
Konno, H1
Itoyama, Y1
Giner, V1
Casademont, J1
Cardellach, F1

Reviews

3 reviews available for fluconazole and Cerebromeningitis

ArticleYear
Cryptococcal meningoencephalitis with Actinomyces odontolyticus sepsis: a case report and literature review.
    BMC infectious diseases, 2023, Jun-27, Volume: 23, Issue:1

    Topics: Actinomyces; Actinomycosis; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Fluconazole;

2023
Cryptococcal meningoencephalitis: time for action.
    The Lancet. Infectious diseases, 2021, Volume: 21, Issue:9

    Topics: Amphotericin B; Antifungal Agents; Cryptococcosis; Databases, Factual; Deoxycholic Acid; Drug Combin

2021
Balamuthia mandrillaris meningoencephalitis in an immunocompetent patient: an unusual clinical course and a favorable outcome.
    Archives of pathology & laboratory medicine, 2004, Volume: 128, Issue:4

    Topics: Aged; Animals; Brain Neoplasms; Central Nervous System Protozoal Infections; Clarithromycin; Diagnos

2004

Other Studies

25 other studies available for fluconazole and Cerebromeningitis

ArticleYear
Pharmacodynamics of ATI-2307 in a rabbit model of cryptococcal meningoencephalitis.
    Antimicrobial agents and chemotherapy, 2023, 10-18, Volume: 67, Issue:10

    Topics: Animals; Antifungal Agents; Cryptococcus neoformans; Fluconazole; Mammals; Meningitis, Cryptococcal;

2023
A multi-arm, parallel, preclinical study investigating the potential benefits of acetazolamide, candesartan, and triciribine in combination with fluconazole for the treatment of cryptococcal meningoencephalitis.
    European journal of pharmacology, 2023, Dec-05, Volume: 960

    Topics: Acetazolamide; Animals; Antifungal Agents; Cryptococcus neoformans; Fluconazole; Humans; Meningitis,

2023
Outcomes in Previously Healthy Cryptococcal Meningoencephalitis Patients Treated With Pulse Taper Corticosteroids for Post-infectious Inflammatory Syndrome.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 11-02, Volume: 73, Issue:9

    Topics: Adrenal Cortex Hormones; Antifungal Agents; Cryptococcus; Fluconazole; Humans; Meningitis, Cryptococ

2021
Rare presentation of cryptococcal meningitis in an immunocompetent patient.
    BMJ case reports, 2019, May-28, Volume: 12, Issue:5

    Topics: Agricultural Workers' Diseases; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Diplopia

2019
Pharmacokinetics and pharmacodynamics of fluconazole for cryptococcal meningoencephalitis: implications for antifungal therapy and in vitro susceptibility breakpoints.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:6

    Topics: Animals; Antifungal Agents; Area Under Curve; Cryptococcus neoformans; Disease Models, Animal; Fluco

2013
Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans.
    PLoS biology, 2013, Volume: 11, Issue:9

    Topics: Aneuploidy; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Drug Resistance, Fungal; Flu

2013
Cryptococcus neoformans meningoencephalitis in a patient with polyarteritis nodosa.
    Folia microbiologica, 2014, Volume: 59, Issue:6

    Topics: Antifungal Agents; Cryptococcus neoformans; Fatal Outcome; Fluconazole; Humans; Male; Meningoencepha

2014
Naegleria fowleri That Induces Primary Amoebic Meningoencephalitis: Rapid Diagnosis and Rare Case of Survival in a 12-Year-Old Caucasian Girl.
    Laboratory medicine, 2016, Volume: 47, Issue:2

    Topics: Amebiasis; Amphotericin B; Antiprotozoal Agents; Azithromycin; Central Nervous System Protozoal Infe

2016
Visual changes in a 4-year-old.
    Clinical pediatrics, 2008, Volume: 47, Issue:9

    Topics: Antifungal Agents; Child, Preschool; Coccidioidomycosis; Diagnosis, Differential; Female; Fluconazol

2008
Cryptococcus gattii meningoencephalitis in an immunocompetent person 13 months after exposure.
    Infection, 2009, Volume: 37, Issue:4

    Topics: Amphotericin B; Antifungal Agents; Cerebrospinal Fluid; Cryptococcosis; Cryptococcus; Culture Media;

2009
Explosive nasofacial cryptococosis.
    Dermatology online journal, 2010, Mar-15, Volume: 16, Issue:3

    Topics: Acids; Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; An

2010
Meningoencephalitis caused by a zygomycete fungus (Basidiobolus) associated with septic shock in an immunocompetent patient: 1-year follow-up after treatment.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2010, Volume: 43, Issue:8

    Topics: Aged; Amphotericin B; Antifungal Agents; Entomophthorales; Fluconazole; Follow-Up Studies; Humans; I

2010
Measurement of antifungal drug levels in cerebrospinal fluid for cryptococcal meningoencephalitis.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2012, Volume: 18, Issue:5

    Topics: Aged; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Fluconazole; Humans; Male; Meningi

2012
A murine model of Cryptococcus gattii meningoencephalitis.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:6

    Topics: Animals; Antifungal Agents; Antigens, Fungal; Brain; Colony Count, Microbial; Cryptococcosis; Crypto

2012
Prototheca wickerhamii as a cause of neuroinfection in a child with congenital hydrocephalus. First case of human protothecosis in Poland.
    Diagnostic microbiology and infectious disease, 2012, Volume: 74, Issue:2

    Topics: Amphotericin B; Antifungal Agents; DNA, Plant; Fluconazole; Head; Humans; Hydrocephalus; Infant; Ket

2012
Limited activity of miltefosine in murine models of cryptococcal meningoencephalitis and disseminated cryptococcosis.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Amphotericin B; Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Deoxycholic Aci

2013
[A patient with coccidioidal meningoencephalitis].
    Rinsho shinkeigaku = Clinical neurology, 2005, Volume: 45, Issue:9

    Topics: Adult; Amphotericin B; Antibodies, Fungal; Antifungal Agents; Brain; Coccidioides; Coccidioidomycosi

2005
Syndrome of inappropriate antidiuretic hormone secretion in a patient with cryptococcal meningoencephalitis: a hidden mediastinal small cell carcinoma.
    The American journal of the medical sciences, 2006, Volume: 331, Issue:5

    Topics: Carcinoma, Small Cell; Cisplatin; Etoposide; Fluconazole; Humans; Hyponatremia; Inappropriate ADH Sy

2006
Cryptococcal meningoencephalitis diagnosed by blood culture.
    Indian journal of medical microbiology, 2007, Volume: 25, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Cryptococcosis; Cryptococc

2007
[A case of cryptococcal meningoencephalitis, which damaged the medial part of the temporal lobe and caused gradually progressing memory disturbance].
    Rinsho shinkeigaku = Clinical neurology, 1994, Volume: 34, Issue:6

    Topics: Aged; Cryptococcosis; Female; Fluconazole; Humans; Memory Disorders; Meningoencephalitis; Temporal L

1994
Disseminated cutaneous and meningeal sporotrichosis in an AIDS patient.
    Diagnostic microbiology and infectious disease, 1994, Volume: 18, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Fluconazole; Humans; Male; Meningoencephalitis; Sporot

1994
Meningoencephalitis caused by Cryptococcus macerans.
    Scandinavian journal of infectious diseases, 1997, Volume: 29, Issue:4

    Topics: Adult; Antifungal Agents; Cryptococcosis; Epilepsy; Fluconazole; Humans; Male; Meningoencephalitis

1997
Cryptococcosis, epileptic seizures and encephalopathy in a HIV-infected patient.
    Praxis, 1997, Dec-03, Volume: 86, Issue:49

    Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Cryptococcus neo

1997
[Steroid-responsive diffuse cerebral white matter lesions in a case of intractable fungal meningoencephalitis].
    No to shinkei = Brain and nerve, 1999, Volume: 51, Issue:1

    Topics: Anti-Inflammatory Agents; Antifungal Agents; Cryptococcosis; Fluconazole; Humans; Male; Meningoencep

1999
Cryptococcal meningoencephalitis and sarcoidosis.
    Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 1999, Volume: 16, Issue:2

    Topics: Adult; Antifungal Agents; Cryptococcus neoformans; Female; Fluconazole; Humans; Meningitis, Cryptoco

1999