fluconazole has been researched along with Central Nervous System Fungal Infections in 19 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Central Nervous System Fungal Infections: MYCOSES of the brain, spinal cord, and meninges which may result in ENCEPHALITIS; MENINGITIS, FUNGAL; MYELITIS; BRAIN ABSCESS; and EPIDURAL ABSCESS. Certain types of fungi may produce disease in immunologically normal hosts, while others are classified as opportunistic pathogens, causing illness primarily in immunocompromised individuals (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with fluconazole 10 mg kg(-1) daily for 6 months was not associated with clinical improvement." | 5.33 | Posaconazole therapy for systemic coccidioidomycosis in a chimpanzee (Pan troglodytes): a case report. ( Herrin, KV; Loebenberg, D; Miranda, A, 2005) |
| "A 49-year-old man with disseminated histoplasmosis (pulmonary and central nervous system involvement) successfully treated with ketoconazole and fluconazole combination is reported." | 3.70 | [Disseminated histoplasmosis caused by Histoplasma capsulatum with cerebral involvement occurring 13 years after the primary infection]. ( Astoul, P; Bérard, H; Boutin, C; Cho, K; Cuguillière, A; Frenay, C, 1999) |
| "Eight patients had symptomatic recurrence of lesions 3-12 weeks after treatment and underwent reoperation." | 2.52 | Intracranial Fungal Granulomas: A Single Institutional Clinicopathologic Study of 66 Patients and Review of the Literature. ( Ahmed, FU; Garg, A; Gupta, A; Mahapatra, AK; Naik, V; Sarkar, C; Sharma, B, 2015) |
| "Treatment with fluconazole was initiated, and the patient's symptoms gradually improved." | 2.45 | [Central nervous system histoplasmosis]. ( Hamada, M; Tsuji, S, 2009) |
| "Fluconazole (37." | 1.36 | Cutaneous cryptococcosis in solid organ transplant recipients. ( Alexander, BD; Del Busto, R; Dowdy, LA; Dromer, F; Fisher, RA; Forrest, GN; Garcia-Diaz, J; Gupta, KL; House, AA; Houston, SH; Humar, A; Huprikar, S; Husain, S; John, GT; Johnson, LB; Kalil, AC; Klintmalm, GB; Limaye, AP; Lortholary, O; Lyon, GM; Morris, MI; Muñoz, P; Orloff, SL; Pruett, TL; Pursell, K; Razonable, RR; Sifri, CD; Singh, N; Somani, J; Stosor, V; Sun, HY; Wagener, MM; Wray, D, 2010) |
| "Treatment with fluconazole 10 mg kg(-1) daily for 6 months was not associated with clinical improvement." | 1.33 | Posaconazole therapy for systemic coccidioidomycosis in a chimpanzee (Pan troglodytes): a case report. ( Herrin, KV; Loebenberg, D; Miranda, A, 2005) |
| "Fluconazole is useful in the treatment of CNS cryptococcosis, because it attains high concentration in the CNS." | 1.32 | Cryptococcosis of the central nervous system in a dog. ( O'Toole, TE; Rozanski, EA; Sato, AF, 2003) |
| "Fluconazole was less effective as a single agent than was amphotericin B, despite the greater penetration of fluconazole into brain tissues." | 1.31 | Antifungal therapy for central nervous system histoplasmosis, using a newly developed intracranial model of infection. ( Brizendine, E; Connolly, PA; Durkin, MM; Haynes, RR; LeMonte, AM; Smedema, ML; Wheat, LJ, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 11 (57.89) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Xiao, H | 2 |
| Miao, Y | 2 |
| Liu, L | 2 |
| Feng, W | 2 |
| Liu, S | 2 |
| Guo, L | 2 |
| Guo, X | 2 |
| Chen, T | 2 |
| Hu, B | 2 |
| Hu, H | 2 |
| Xu, F | 2 |
| Han, L | 2 |
| Ren, L | 2 |
| Li, W | 2 |
| Liu, G | 2 |
| Lahiri Mukhopadhyay, S | 1 |
| Bahubali, VH | 1 |
| Manjunath, N | 1 |
| Swaminathan, A | 1 |
| Maji, S | 1 |
| Palaniappan, M | 1 |
| Parthasarathy, S | 1 |
| Chandrashekar, N | 1 |
| Naik, V | 1 |
| Ahmed, FU | 1 |
| Gupta, A | 1 |
| Garg, A | 1 |
| Sarkar, C | 1 |
| Sharma, B | 1 |
| Mahapatra, AK | 1 |
| Hamada, M | 1 |
| Tsuji, S | 1 |
| Sun, HY | 1 |
| Alexander, BD | 1 |
| Lortholary, O | 1 |
| Dromer, F | 1 |
| Forrest, GN | 1 |
| Lyon, GM | 1 |
| Somani, J | 1 |
| Gupta, KL | 1 |
| Del Busto, R | 1 |
| Pruett, TL | 1 |
| Sifri, CD | 1 |
| Limaye, AP | 1 |
| John, GT | 1 |
| Klintmalm, GB | 1 |
| Pursell, K | 1 |
| Stosor, V | 1 |
| Morris, MI | 1 |
| Dowdy, LA | 1 |
| Muñoz, P | 1 |
| Kalil, AC | 1 |
| Garcia-Diaz, J | 1 |
| Orloff, SL | 1 |
| House, AA | 1 |
| Houston, SH | 1 |
| Wray, D | 1 |
| Huprikar, S | 1 |
| Johnson, LB | 1 |
| Humar, A | 1 |
| Razonable, RR | 1 |
| Fisher, RA | 1 |
| Husain, S | 1 |
| Wagener, MM | 1 |
| Singh, N | 1 |
| Mendes, FE | 1 |
| Oliveira, LV | 1 |
| Faria, ES | 1 |
| Alvarenga, DG | 1 |
| Pinto, MR | 1 |
| Taborda, CP | 1 |
| Soares, BM | 1 |
| Cisalpino, PS | 1 |
| Santos, DA | 1 |
| Brick, KE | 1 |
| Agger, WA | 1 |
| O'Toole, TE | 1 |
| Sato, AF | 1 |
| Rozanski, EA | 1 |
| Levi, GC | 1 |
| Pozzi, CM | 1 |
| Hirschheimer, SM | 1 |
| Chahade, WH | 1 |
| Gomes, HR | 1 |
| Granato, C | 1 |
| Yasuda, MA | 1 |
| Gasparetto, EL | 1 |
| Carvalho Neto, Ad | 1 |
| Alberton, J | 1 |
| Davaus, T | 1 |
| Pianovski, MA | 1 |
| Yamauchi, E | 1 |
| Torres, LF | 1 |
| Herrin, KV | 1 |
| Miranda, A | 1 |
| Loebenberg, D | 1 |
| Rosendahl, M | 1 |
| Kvinesdal, B | 1 |
| Mathai, AM | 1 |
| Khadilkar, UN | 1 |
| Knapp, S | 1 |
| Turnherr, M | 1 |
| Dekan, G | 1 |
| Willinger, B | 1 |
| Stingl, G | 1 |
| Rieger, A | 1 |
| Bérard, H | 1 |
| Astoul, P | 1 |
| Frenay, C | 1 |
| Cuguillière, A | 1 |
| Cho, K | 1 |
| Boutin, C | 1 |
| Vidal, F | 1 |
| Mirón, M | 1 |
| Sirvent, JJ | 1 |
| Richart, C | 1 |
| Kusanagi, H | 1 |
| Shimura, T | 1 |
| Teramoto, A | 1 |
| Haynes, RR | 1 |
| Connolly, PA | 1 |
| Durkin, MM | 1 |
| LeMonte, AM | 1 |
| Smedema, ML | 1 |
| Brizendine, E | 1 |
| Wheat, LJ | 1 |
3 reviews available for fluconazole and Central Nervous System Fungal Infections
| Article | Year |
|---|---|
Intracranial Fungal Granulomas: A Single Institutional Clinicopathologic Study of 66 Patients and Review of the Literature.
Topics: Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Brain; Central Nervous System Fungal Inf | 2015 |
[Central nervous system histoplasmosis].
Topics: Antifungal Agents; Central Nervous System Fungal Infections; Cerebrospinal Fluid; Diagnosis, Differe | 2009 |
Pharmacological management of paracoccidioidomycosis.
Topics: Amphotericin B; Central Nervous System Fungal Infections; Drug Resistance; Fluconazole; Follow-Up St | 2005 |
1 trial available for fluconazole and Central Nervous System Fungal Infections
| Article | Year |
|---|---|
[The usefulness of fluconazole administration and beta-D-glucan measurement in neurosurgical patients with deep-seated mycosis].
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; beta-Glucans; Biomarkers; Central Nervous System | 2000 |
15 other studies available for fluconazole and Central Nervous System Fungal Infections
| Article | Year |
|---|---|
Clinical characteristics of central nervous system candidiasis due to Candida albicans in children: a single-center experience.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Central Nervous System; Central Nervous System Fun | 2022 |
Clinical characteristics of central nervous system candidiasis due to Candida albicans in children: a single-center experience.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Central Nervous System; Central Nervous System Fun | 2022 |
Clinical characteristics of central nervous system candidiasis due to Candida albicans in children: a single-center experience.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Central Nervous System; Central Nervous System Fun | 2022 |
Clinical characteristics of central nervous system candidiasis due to Candida albicans in children: a single-center experience.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Central Nervous System; Central Nervous System Fun | 2022 |
Central nervous system infection due to Cryptococcus gattii sensu lato in India: Analysis of clinical features, molecular profile and antifungal susceptibility.
Topics: Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Central Nervous System Fungal Infections | 2017 |
Cutaneous cryptococcosis in solid organ transplant recipients.
Topics: Antifungal Agents; Central Nervous System Fungal Infections; Cohort Studies; Cryptococcosis; Cryptoc | 2010 |
Correlation of the in vitro antifungal drug susceptibility with the in vivo activity of fluconazole in a murine model of cerebral infection caused by Cryptococcus gattii.
Topics: Animals; Antifungal Agents; Brain; Central Nervous System Fungal Infections; Cryptococcosis; Cryptoc | 2010 |
Successful treatment of brainstem blastomycosis with fluconazole.
Topics: Adult; Antifungal Agents; Blastomyces; Blastomycosis; Brain Stem; Central Nervous System Fungal Infe | 2012 |
Cryptococcosis of the central nervous system in a dog.
Topics: Animals; Antifungal Agents; Central Nervous System; Central Nervous System Fungal Infections; Crypto | 2003 |
[Central nervous system involvement by histoplasmosis as the unique manifestation of this disease in immunocompetent patients: presentation of two cases].
Topics: Adult; Antifungal Agents; Central Nervous System Fungal Infections; Child; Female; Fluconazole; Hist | 2003 |
[Histoplasmoma as isolated central nervous system lesion in an immunocompetent patient].
Topics: Adolescent; Antifungal Agents; Biopsy; Central Nervous System Fungal Infections; Fluconazole; Histop | 2005 |
Posaconazole therapy for systemic coccidioidomycosis in a chimpanzee (Pan troglodytes): a case report.
Topics: Animals; Antibodies, Fungal; Antifungal Agents; Ape Diseases; Blood; Central Nervous System Fungal I | 2005 |
Coccidioidomycosis with cerebral and cerebellar granulomas.
Topics: Adult; Antifungal Agents; Arizona; Central Nervous System Fungal Infections; Cerebellar Diseases; Co | 2006 |
Candidosis of brain.
Topics: Aged; Antifungal Agents; Brain; Candidiasis; Central Nervous System Fungal Infections; Diabetes Comp | 2007 |
A case of HIV-associated cerebral histoplasmosis successfully treated with fluconazole.
Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Brain Diseases; Central Nervous Sys | 1999 |
[Disseminated histoplasmosis caused by Histoplasma capsulatum with cerebral involvement occurring 13 years after the primary infection].
Topics: Antifungal Agents; Brain; Brain Diseases; Central Nervous System Fungal Infections; Fluconazole; His | 1999 |
Central nervous system pneumocystosis in AIDS: antemortem diagnosis and successful treatment.
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Anti-HIV Agents; Antifungal Agents; Ce | 2000 |
Antifungal therapy for central nervous system histoplasmosis, using a newly developed intracranial model of infection.
Topics: Amphotericin B; Animals; Antifungal Agents; Brain; Central Nervous System Fungal Infections; Disease | 2002 |