Page last updated: 2024-10-27

fluconazole and Central Nervous System Disease

fluconazole has been researched along with Central Nervous System Disease in 6 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Research Excerpts

ExcerptRelevanceReference
"Treatment with fluconazole is only recommended for localised pulmonary disease."1.62Treatment and mortality outcomes in patients with other extrapulmonary cryptococcal disease compared with central nervous system disease. ( Larson, L; Mejia-Chew, C; Powderly, WG; Spec, A; Sung, A, 2021)
"Histoplasmosis is an important cause of morbidity and death in HIV-infected patients."1.30Histoplasmosis: update 1998. ( Brooks, JT; Wheat, LJ, 1998)
"0 microgram of IL-12 per day was found to be the optimal dosage for reducing infection in the brain."1.29Cytokine treatment of central nervous system infection: efficacy of interleukin-12 alone and synergy with conventional antifungal therapy in experimental cryptococcosis. ( Brummer, E; Clemons, KV; Stevens, DA, 1994)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Mejia-Chew, C1
Sung, A1
Larson, L1
Powderly, WG1
Spec, A1
Clemons, KV1
Brummer, E1
Stevens, DA1
Bozzette, SA1
Brooks, JT1
Wheat, LJ1
Cochius, JI1
Burns, RJ1
Willoughby, JO1
Arndt, CA1
Walsh, TJ1
McCully, CL1
Balis, FM1
Pizzo, PA1
Poplack, DG1

Reviews

1 review available for fluconazole and Central Nervous System Disease

ArticleYear
The management of cryptococcal disease in patients with AIDS.
    Current clinical topics in infectious diseases, 1993, Volume: 13

    Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Central Nervous System Dis

1993

Other Studies

5 other studies available for fluconazole and Central Nervous System Disease

ArticleYear
Treatment and mortality outcomes in patients with other extrapulmonary cryptococcal disease compared with central nervous system disease.
    Mycoses, 2021, Volume: 64, Issue:2

    Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Central Nervous System Diseases; Cryptococcosis; Cry

2021
Cytokine treatment of central nervous system infection: efficacy of interleukin-12 alone and synergy with conventional antifungal therapy in experimental cryptococcosis.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:3

    Topics: Animals; Central Nervous System Diseases; Colony Count, Microbial; Cryptococcosis; Drug Synergism; F

1994
Histoplasmosis: update 1998.
    AIDS clinical care, 1998, Volume: 10, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Central Nervous System Dis

1998
CNS cryptococcosis: unusual aspects.
    Clinical and experimental neurology, 1989, Volume: 26

    Topics: Adult; Aged; Amphotericin B; Central Nervous System Diseases; Cryptococcosis; Female; Fluconazole; F

1989
Fluconazole penetration into cerebrospinal fluid: implications for treating fungal infections of the central nervous system.
    The Journal of infectious diseases, 1988, Volume: 157, Issue:1

    Topics: Animals; Central Nervous System Diseases; Cryptococcosis; Fluconazole; Macaca mulatta; Male; Triazol

1988