Page last updated: 2024-10-27

fluconazole and Canine Diseases

fluconazole has been researched along with Canine Diseases in 33 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Research Excerpts

ExcerptRelevanceReference
"To characterize the clinical course and therapeutic response in dogs with coccidioidomycosis treated with fluconazole."8.12Retrospective evaluation of the efficacy of fluconazole for the treatment of coccidioidomycosis in dogs: 49 cases (2015-2020). ( Carter, TD; Foy, DS; Fuller, BD; Shaver, SL, 2022)
"The majority of dogs with coccidioidomycosis recover with administration of fluconazole or itraconazole, although some cases are refractory or the dogs do not tolerate administration of these medications."8.02Posaconazole treatment of refractory coccidioidomycosis in dogs. ( Butkiewicz, CD; Schlacks, S; Shubitz, LF; Vishkautsan, P; Worthing, KA, 2021)
"To characterize the clinical course and therapeutic response in dogs with coccidioidomycosis treated with fluconazole."4.12Retrospective evaluation of the efficacy of fluconazole for the treatment of coccidioidomycosis in dogs: 49 cases (2015-2020). ( Carter, TD; Foy, DS; Fuller, BD; Shaver, SL, 2022)
"The majority of dogs with coccidioidomycosis recover with administration of fluconazole or itraconazole, although some cases are refractory or the dogs do not tolerate administration of these medications."4.02Posaconazole treatment of refractory coccidioidomycosis in dogs. ( Butkiewicz, CD; Schlacks, S; Shubitz, LF; Vishkautsan, P; Worthing, KA, 2021)
" The present report suggested that combined management of granulomas with surgery and newer triazole medications such as voriconazole may represent a novel strategy that improves the prognosis for this disease."3.77Successful management of an intracranial phaeohyphomycotic fungal granuloma in a dog. ( Bentley, RT; Faissler, D; Sutherland-Smith, J, 2011)
"To describe the clinical management of a case of Candida albicans peritonitis in a dog and discuss the pathogenicity of Candida peritonitis along with treatment using the fungistatic agent, fluconazole."3.76Candida albicans peritonitis in a dog. ( Ong, RK; Raisis, AL; Swindells, KL, 2010)
"7 of 8 dogs receiving combination drug therapy consisting of flucytosine together with amphotericin B and/or a triazole for cryptococcosis or aspergillosis developed cutaneous or mucocutaneous eruptions during the course of treatment."3.69Suspected drug eruption in seven dogs during administration of flucytosine. ( Love, DN; Malik, R; Medeiros, C; Wigney, DI, 1996)
"To assess the pharmacokinetics, clinical efficacy, and adverse effects of injectable methadone with the pharmacokinetic enhancer fluconazole (methadone-fluconazole), compared with the standard formulation of injectable methadone, in dogs after ovariohysterectomy."3.11Long-acting injectable methadone (methadone-fluconazole) provides safe and effective postoperative analgesia in a randomized clinical trial for dogs undergoing soft tissue surgery. ( Berke, KA; Bieberly, ZD; Comroe, AJ; Fitzgerald, AH; Jugan, MC; Klocke, EE; Klutzke, JB; KuKanich, B; KuKanich, KS; Mason, DE; Orchard, RJ; Upchurch, DA; Woodruff, K, 2022)
" Blood samples were collected for pharmacokinetic analysis, and rectal temperature and sedation were assessed to evaluate opioid effects at predetermined times up to 24 hours after treatment."2.94Pharmacokinetics and pharmacodynamics of a novel analgesic with a deterrent to human opioid abuse (methadone-fluconazole-naltrexone) after oral administration in dogs. ( Joo, H; KuKanich, B; KuKanich, K; Locuson, CW; Rankin, DC, 2020)
"To assess the pharmacokinetics and opioid effects of methadone after administration of multiple doses by means of 2 dosing regimens of methadone-fluconazole-naltrexone."1.62Multiple-dose pharmacokinetics and opioid effects of a novel analgesic with a deterrent to human opioid abuse (methadone-fluconazole-naltrexone) after oral administration in dogs. ( Cho, P; Fitzgerald, AH; Komp, MS; KuKanich, B; KuKanich, K; Locuson, CW; Rankin, DC, 2021)
"Amphotericin B was thus an effective agent for treating severe cases of cryptococcosis."1.33Long-term outcome of therapy for 59 cats and 11 dogs with cryptococcosis. ( Krockenberger, MB; Malik, R; Martin, P; O'Brien, CR; Wigney, DI, 2006)
"Fluconazole is useful in the treatment of CNS cryptococcosis, because it attains high concentration in the CNS."1.32Cryptococcosis of the central nervous system in a dog. ( O'Toole, TE; Rozanski, EA; Sato, AF, 2003)
"Blastomycosis was detected mainly in young, large-breed dogs."1.30Blastomycosis in dogs: 115 cases (1980-1995). ( Arceneaux, KA; Hosgood, G; Taboada, J, 1998)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (12.12)18.2507
2000's5 (15.15)29.6817
2010's16 (48.48)24.3611
2020's8 (24.24)2.80

Authors

AuthorsStudies
Shubitz, LF1
Schlacks, S1
Vishkautsan, P1
Butkiewicz, CD1
Worthing, KA1
Carter, TD1
Fuller, BD1
Shaver, SL1
Foy, DS1
Bieberly, ZD1
KuKanich, B4
KuKanich, KS1
Berke, KA1
Klocke, EE2
Upchurch, DA2
Comroe, AJ1
Jugan, MC1
Mason, DE1
Orchard, RJ1
Klutzke, JB1
Fitzgerald, AH3
Woodruff, K1
Váczi, P1
Čonková, E1
Malinovská, Z1
Piech, TL1
Jaffey, JA1
Hostnik, ET1
White, ME1
KuKanich, K3
Rankin, DC3
Locuson, CW2
Joo, H1
Comroe, A1
Crauer, B1
Berke, K1
Gonzalez, SE1
Mason, D1
Jensen, G1
Orchard, R1
Cho, P2
Komp, M1
Komp, MS1
Block, K1
Battig, J1
Kano, R1
Yokoi, S1
Kariya, N1
Oshimo, K1
Kamata, H1
Brilhante, RSN1
Rocha, MGD1
Guedes, GMM1
Oliveira, JS1
Araújo, GDS1
España, JDA1
Sales, JA1
Aguiar, L1
Paiva, MAN1
Cordeiro, RA1
Pereira-Neto, WA1
Pinheiro, AQ1
Sidrim, JJC1
Castelo-Branco, DSCM1
Rocha, MFG1
Spoor, MS1
Zigioli, VA1
Jacocks, KA1
Agut, A1
Boza, S1
Murciano, J1
Belda, E1
Soler, M1
Barrs, VR1
van Doorn, TM1
Houbraken, J1
Kidd, SE1
Martin, P2
Pinheiro, MD1
Richardson, M1
Varga, J1
Samson, RA1
Kurach, L1
Wojnarowicz, C1
Wilkinson, T1
Sereda, C1
Uchiumi, K1
Stowe, DM1
DeVanna, JC1
Willcox, JL1
Neel, JA1
Sherman, A1
Ham, K1
Costa, A1
Lahmers, S1
Barry, SL1
Stanton, J1
Stern, JA1
Ong, RK1
Raisis, AL1
Swindells, KL1
Sickafoose, L1
Hosgood, G2
Snook, T1
Westermeyer, R1
Merchant, S1
Clemans, JM1
Deitz, KL1
Riedesel, EA1
Yaeger, MJ1
Legendre, AM1
Bentley, RT1
Faissler, D1
Sutherland-Smith, J1
Cafarchia, C1
Figueredo, LA1
Iatta, R1
Montagna, MT1
Otranto, D1
Walker, JT1
Frazho, JK1
Randell, SC1
O'Toole, TE1
Sato, AF1
Rozanski, EA1
Grooters, AM1
Taboada, J2
Heseltine, JC1
Panciera, DL1
Saunders, GK1
Welihozkiy, A1
Franks, JN1
O'Brien, CR1
Krockenberger, MB1
Wigney, DI2
Malik, R2
Coates, JR1
Medeiros, C1
Love, DN1
Arceneaux, KA1
Lambrechts, N1
Collett, MG1
Henton, M1

Reviews

1 review available for fluconazole and Canine Diseases

ArticleYear
Update on antifungal therapy.
    The Veterinary clinics of North America. Small animal practice, 2003, Volume: 33, Issue:4

    Topics: Amphotericin B; Animals; Anti-Bacterial Agents; Antifungal Agents; Caspofungin; Cat Diseases; Cats;

2003

Trials

3 trials available for fluconazole and Canine Diseases

ArticleYear
Long-acting injectable methadone (methadone-fluconazole) provides safe and effective postoperative analgesia in a randomized clinical trial for dogs undergoing soft tissue surgery.
    American journal of veterinary research, 2022, Jun-13, Volume: 83, Issue:8

    Topics: Analgesia; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Female; Fluconazole; Hysterectomy; Metha

2022
Pharmacokinetics and pharmacodynamics of a novel analgesic with a deterrent to human opioid abuse (methadone-fluconazole-naltrexone) after oral administration in dogs.
    American journal of veterinary research, 2020, Volume: 81, Issue:8

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Fluconazole; Methadone; Naltr

2020
A noninferiority clinical trial comparing fluconazole and ketoconazole in combination with cephalexin for the treatment of dogs with Malassezia dermatitis.
    Veterinary therapeutics : research in applied veterinary medicine, 2010,Summer, Volume: 11, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Cephalexin; Dermatomycoses; Dog Diseases; Dogs; D

2010

Other Studies

29 other studies available for fluconazole and Canine Diseases

ArticleYear
Posaconazole treatment of refractory coccidioidomycosis in dogs.
    Journal of veterinary internal medicine, 2021, Volume: 35, Issue:6

    Topics: Animals; Antifungal Agents; Coccidioidomycosis; Dog Diseases; Dogs; Fluconazole; Retrospective Studi

2021
Retrospective evaluation of the efficacy of fluconazole for the treatment of coccidioidomycosis in dogs: 49 cases (2015-2020).
    Journal of the American Veterinary Medical Association, 2022, 05-11, Volume: 260, Issue:10

    Topics: Animals; Coccidioidomycosis; Dog Diseases; Dogs; Fluconazole; Lethargy; Retrospective Studies

2022
Efficacy of manuka honey with conventional antifungals on
    Polish journal of veterinary sciences, 2023, Volume: 26, Issue:2

    Topics: Animals; Antifungal Agents; Azoles; Cat Diseases; Cats; Clotrimazole; Dog Diseases; Dogs; Fluconazol

2023
Bicavitary eosinophilic effusion in a dog with coccidioidomycosis.
    Journal of veterinary internal medicine, 2020, Volume: 34, Issue:4

    Topics: Animals; Antifungal Agents; Ascitic Fluid; Bone Diseases; Coccidioides; Coccidioidomycosis; Dog Dise

2020
Perioperative analgesia associated with oral administration of a novel methadone-fluconazole-naltrexone formulation in dogs undergoing routine ovariohysterectomy.
    American journal of veterinary research, 2020, Volume: 81, Issue:9

    Topics: Administration, Oral; Analgesia; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Female; Fluconazol

2020
Multiple-dose pharmacokinetics and opioid effects of a novel analgesic with a deterrent to human opioid abuse (methadone-fluconazole-naltrexone) after oral administration in dogs.
    American journal of veterinary research, 2021, Volume: 82, Issue:3

    Topics: Administration, Oral; Analgesics; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Fluconazole; Huma

2021
Cryptococcal Maxillary Osteomyelitis and Osteonecrosis in a 18-Month-Old Dog.
    Journal of veterinary dentistry, 2017, Volume: 34, Issue:2

    Topics: Animals; Antifungal Agents; Cryptococcosis; Cryptococcus; Debridement; Dog Diseases; Dogs; Fluconazo

2017
Multi-azole-resistant strain of Malassezia pachydermatis isolated from a canine Malassezia dermatitis.
    Medical mycology, 2019, Apr-01, Volume: 57, Issue:3

    Topics: Animals; Antifungal Agents; Azoles; Cytochrome P-450 Enzyme System; Dermatitis; Dermatomycoses; Dog

2019
Malassezia pachydermatis from animals: Planktonic and biofilm antifungal susceptibility and its virulence arsenal.
    Veterinary microbiology, 2018, Volume: 220

    Topics: Animals; Antifungal Agents; Bacterial Adhesion; Biofilms; Caenorhabditis elegans; Cat Diseases; Cats

2018
What is your diagnosis? Bronchoalveolar wash fluid from a dog.
    Veterinary clinical pathology, 2019, Volume: 48, Issue:4

    Topics: Animals; Antifungal Agents; Bronchoalveolar Lavage Fluid; Dog Diseases; Dogs; Female; Fluconazole; L

2019
What is your diagnosis? Cryptococcal patellar osteomyelitis.
    Journal of the American Veterinary Medical Association, 2013, Mar-15, Volume: 242, Issue:6

    Topics: Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Dog Diseases; Dogs; Fluconazole

2013
Aspergillus felis sp. nov., an emerging agent of invasive aspergillosis in humans, cats, and dogs.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Air Microbiology; Animals; Antifungal Agents; Aspergillosis; Aspergillus; Caspofungin; Cat Diseases;

2013
Acute hind limb paralysis secondary to an extradural spinal cord Cryptococcus gattii lesion in a dog.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2013, Volume: 54, Issue:5

    Topics: Animals; Antifungal Agents; Cryptococcosis; Cryptococcus gattii; Decompression, Surgical; Dog Diseas

2013
Pathology in practice. Cryptococcus sp in a dog.
    Journal of the American Veterinary Medical Association, 2014, Oct-15, Volume: 245, Issue:8

    Topics: Amphotericin B; Animals; Antifungal Agents; Cryptococcosis; Cryptococcus; Dog Diseases; Dogs; Fatal

2014
What is your diagnosis? Coccidioidomycosis.
    Journal of the American Veterinary Medical Association, 2014, Dec-15, Volume: 245, Issue:12

    Topics: Animals; Antifungal Agents; Coccidioidomycosis; Dog Diseases; Dogs; Female; Fluconazole; Osteomyelit

2014
Fungal pericarditis and endocarditis secondary to porcupine quill migration in a dog.
    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2014, Volume: 16, Issue:4

    Topics: Animals; Antifungal Agents; Dog Diseases; Dogs; Endocarditis; Fluconazole; Foreign Bodies; Male; Myc

2014
Candida albicans peritonitis in a dog.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2010, Volume: 20, Issue:1

    Topics: Animals; Antifungal Agents; Candidiasis; Dog Diseases; Dogs; Fluconazole; Male; Peritonitis; Surgica

2010
Retroperitoneal pyogranulomatous and fibrosing inflammation secondary to fungal infections in two dogs.
    Journal of the American Veterinary Medical Association, 2011, Jan-15, Volume: 238, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Blastomyces; Blastomycosis; Dog Diseases; Dogs; D

2011
Successful management of an intracranial phaeohyphomycotic fungal granuloma in a dog.
    Journal of the American Veterinary Medical Association, 2011, Aug-15, Volume: 239, Issue:4

    Topics: Animals; Antifungal Agents; Cerebral Phaeohyphomycosis; Dog Diseases; Dogs; Fluconazole; Granuloma;

2011
In vitro antifungal susceptibility of Malassezia pachydermatis from dogs with and without skin lesions.
    Veterinary microbiology, 2012, Mar-23, Volume: 155, Issue:2-4

    Topics: Animals; Antifungal Agents; Dermatomycoses; Dog Diseases; Dogs; Fluconazole; Itraconazole; Ketoconaz

2012
A novel case of canine disseminated aspergillosis following mating.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2012, Volume: 53, Issue:2

    Topics: Animals; Antifungal Agents; Aspergillosis; Copulation; Dog Diseases; Dogs; Fatal Outcome; Female; Fl

2012
Cryptococcosis of the central nervous system in a dog.
    Journal of the American Veterinary Medical Association, 2003, Jun-15, Volume: 222, Issue:12

    Topics: Animals; Antifungal Agents; Central Nervous System; Central Nervous System Fungal Infections; Crypto

2003
Systemic candidiasis in a dog.
    Journal of the American Veterinary Medical Association, 2003, Sep-15, Volume: 223, Issue:6

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Catheters, Indwelling; Dog Diseases; Dogs

2003
What is your diagnosis? Fungal osteomyelitis.
    Journal of the American Veterinary Medical Association, 2006, Apr-01, Volume: 228, Issue:7

    Topics: Amputation, Surgical; Animals; Antifungal Agents; Ataxia; Dog Diseases; Dogs; Female; Fluconazole; I

2006
Long-term outcome of therapy for 59 cats and 11 dogs with cryptococcosis.
    Australian veterinary journal, 2006, Volume: 84, Issue:11

    Topics: Amphotericin B; Animals; Antiprotozoal Agents; Cat Diseases; Cats; Cryptosporidiosis; Dog Diseases;

2006
What is your neurologic diagnosis? An atypical case of diskspondylitis caused by Aspergillus spp.
    Journal of the American Veterinary Medical Association, 1995, May-01, Volume: 206, Issue:9

    Topics: Animals; Aspergillosis; Discitis; Dog Diseases; Dogs; Fatal Outcome; Female; Fluconazole; Lumbar Ver

1995
Suspected drug eruption in seven dogs during administration of flucytosine.
    Australian veterinary journal, 1996, Volume: 74, Issue:4

    Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Cryptococcosis; Dog Diseases; Dogs; Drug

1996
Blastomycosis in dogs: 115 cases (1980-1995).
    Journal of the American Veterinary Medical Association, 1998, Sep-01, Volume: 213, Issue:5

    Topics: Age Distribution; Amphotericin B; Animals; Antibodies, Fungal; Antifungal Agents; Blastomyces; Blast

1998
Black grain eumycetoma (Madurella mycetomatis) in the abdominal cavity of a dog.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1991, Volume: 29, Issue:3

    Topics: Abdomen; Animals; Culture Media; Dog Diseases; Dogs; Escherichia coli; Female; Fluconazole; Granulom

1991