fluconazole has been researched along with Cancer of Head in 18 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients undergoing radiotherapy for head and neck cancer are at increased risk of developing oral candidiasis." | 2.71 | Prophylactic treatment of mycotic mucositis in radiotherapy of patients with head and neck cancers. ( Aktas, E; Koc, M, 2003) |
| "Thirty-seven patients with head-and-neck cancer received EBRT in 2." | 2.71 | Oropharyngeal candidiasis caused by non-albicans yeast in patients receiving external beam radiotherapy for head-and-neck cancer. ( Coco, BJ; Dahiya, MC; Dahiya, RS; Eng, TY; Fothergill, AW; Kirkpatrick, WR; Patterson, TF; Redding, SW; Rinaldi, MG; Sadkowski, LC; Thomas, CR; Waite, A, 2003) |
| " The incidence of adverse events was 39% for fluconazole and 44% for amphotericin B." | 2.70 | A comparative study of the efficacy and safety of fluconazole oral suspension and amphotericin B oral suspension in cancer patients with mucositis. ( Domenge, C; Lefebvre, JL, 2002) |
| "Fluconazole was well tolerated and no early or late toxicity was observed." | 2.68 | [Can the prophylactic treatment of mycotic mucositis improve the time of performing radiotherapy in head and neck tumors?]. ( Coghetto, F; Ferrarese, F; Gava, A; Marazzato, G; Tonetto, V; Zorat, PL, 1996) |
| "Hyposalivation is a long-term effect in patients receiving head and neck radiation." | 1.38 | Evaluation of saliva flow rates, Candida colonization and susceptibility of Candida strains after head and neck radiation. ( Al-Nawas, B; Karbach, J; Walter, C, 2012) |
| "Micafungin has excellent antifungal effects in vitro against C." | 1.35 | Antifungal susceptibility testing of micafungin against Candida glabrata isolates. ( Fothergill, A; Kirkpatrick, WR; Oliveira, ER; Patterson, TF; Redding, SW, 2008) |
| "Oral candidiasis was diagnosed using the criteria described before." | 1.33 | Effect of fluconazole antifungal prophylaxis on oral mucositis in head and neck cancer patients receiving radiotherapy. ( Dardoufas, K; Kolitsi, G; Kouloulias, V; Kouvaris, J; Kyprianou, K; Nicolatou-Galitis, O; Papanicolaou, VS; Pissakas, G; Skarleas, C; Sotiropoulou-Lontou, A; Velegraki, A, 2006) |
| "isolated from head and neck cancer patients treated with radiotherapy or chemotherapy to antifungal agents." | 1.33 | [Antifugal susceptibility testing and antifugal traditional Chinese medicines screening of oral Candida isolated from head and neck cancer patients treated with radiotherapy or chemotherapy]. ( Zhang, WD; Zhao, M; Zhou, ZT, 2006) |
| "Fluconazole was measured by liquid chromatography." | 1.29 | Influence of local radiotherapy on penetration of fluconazole into human saliva. ( Brion, N; Frachet, B; Le Gros, V; Louchahi, K; Oliary, J; Petitjean, O; Tod, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Hatami, F | 1 |
| Manifar, S | 1 |
| Asghari-Paskiabi, F | 1 |
| Bagheri Amiri, F | 1 |
| Nojoumi, SA | 1 |
| Jahanshiri, Z | 1 |
| Karbach, J | 1 |
| Walter, C | 1 |
| Al-Nawas, B | 1 |
| Koc, M | 1 |
| Aktas, E | 1 |
| Dahiya, MC | 1 |
| Redding, SW | 6 |
| Dahiya, RS | 1 |
| Eng, TY | 2 |
| Kirkpatrick, WR | 6 |
| Coco, BJ | 3 |
| Sadkowski, LC | 1 |
| Fothergill, AW | 5 |
| Waite, A | 1 |
| Rinaldi, MG | 5 |
| Patterson, TF | 6 |
| Thomas, CR | 1 |
| Burn, AK | 1 |
| McCarthy, DI | 1 |
| Nicolatou-Galitis, O | 1 |
| Velegraki, A | 1 |
| Sotiropoulou-Lontou, A | 1 |
| Dardoufas, K | 1 |
| Kouloulias, V | 1 |
| Kyprianou, K | 1 |
| Kolitsi, G | 1 |
| Skarleas, C | 1 |
| Pissakas, G | 1 |
| Papanicolaou, VS | 1 |
| Kouvaris, J | 1 |
| Zhao, M | 1 |
| Zhou, ZT | 1 |
| Zhang, WD | 1 |
| Oliveira, ER | 1 |
| Fothergill, A | 1 |
| Corvò, R | 1 |
| Amichetti, M | 1 |
| Ascarelli, A | 1 |
| Arcangeli, G | 1 |
| Buffoli, A | 1 |
| Cellini, N | 1 |
| Cionini, L | 1 |
| De Renzis, C | 1 |
| Emiliani, E | 1 |
| Franchini, P | 1 |
| Gabriele, P | 1 |
| Gobitti, C | 1 |
| Grillo Ruggieri, F | 1 |
| Bertoni, F | 1 |
| Magrini, SM | 1 |
| Marmiroli, L | 1 |
| Orsatti, M | 1 |
| Panizza, GM | 1 |
| Tordiglione, M | 1 |
| Ziccarelli, L | 1 |
| Gava, A | 2 |
| Zorat, PL | 2 |
| Ghelfi, R | 1 |
| Serra, GF | 1 |
| Vitale, V | 1 |
| Oliary, J | 1 |
| Tod, M | 1 |
| Louchahi, K | 1 |
| Petitjean, O | 1 |
| Frachet, B | 1 |
| Le Gros, V | 1 |
| Brion, N | 1 |
| Ferrarese, F | 1 |
| Tonetto, V | 1 |
| Coghetto, F | 1 |
| Marazzato, G | 1 |
| Finlay, PM | 1 |
| Richardson, MD | 1 |
| Robertson, AG | 1 |
| Mücke, R | 2 |
| Kaben, U | 2 |
| Libera, T | 2 |
| Knauerhase, H | 2 |
| Ziegler, PG | 2 |
| Hamann, D | 2 |
| Strietzel, M | 2 |
| Zellars, RC | 1 |
| McAtee, RK | 1 |
| Caceres, MA | 1 |
| Lopez-Ribot, JL | 2 |
| Bailey, CW | 2 |
| Sadkowski, L | 1 |
| Lefebvre, JL | 1 |
| Domenge, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Influence of Glutamine on the Side Effects of Chemo-radiation in Head and Neck Cancer Patients - A Randomized Controlled Trial[NCT02282839] | Phase 3 | 60 participants (Anticipated) | Interventional | 2015-01-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 trials available for fluconazole and Cancer of Head
| Article | Year |
|---|---|
Prophylactic treatment of mycotic mucositis in radiotherapy of patients with head and neck cancers.
Topics: Adult; Aged; Antifungal Agents; Candidiasis, Oral; Double-Blind Method; Female; Fluconazole; Head an | 2003 |
Oropharyngeal candidiasis caused by non-albicans yeast in patients receiving external beam radiotherapy for head-and-neck cancer.
Topics: Adult; Aged; Candida; Candida tropicalis; Candidiasis, Oral; Female; Fluconazole; Head and Neck Neop | 2003 |
Effects of fluconazole in the prophylaxis of oropharyngeal candidiasis in patients undergoing radiotherapy for head and neck tumour: results from a double-blind placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Candidiasis, Oral; Double-Blind Metho | 2008 |
[Can the prophylactic treatment of mycotic mucositis improve the time of performing radiotherapy in head and neck tumors?].
Topics: Antifungal Agents; Combined Modality Therapy; Female; Fluconazole; Head and Neck Neoplasms; Humans; | 1996 |
A comparative study of the efficacy of fluconazole and amphotericin B in the treatment of oropharyngeal candidosis in patients undergoing radiotherapy for head and neck tumours.
Topics: Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Candidiasis, Oral; Colony Count, | 1996 |
[Use of fluconazole as antimycotic prophylaxis in radiotherapy of patients with head and neck tumors].
Topics: Antifungal Agents; Candida; Candida albicans; Candidiasis, Oral; Carcinoma, Squamous Cell; Fluconazo | 1997 |
Fluconazole prophylaxis in patients with head and neck tumours undergoing radiation and radiochemotherapy.
Topics: Adult; Aged; Antifungal Agents; Candidiasis, Oral; Carcinoma, Squamous Cell; Combined Modality Thera | 1998 |
A comparative study of the efficacy and safety of fluconazole oral suspension and amphotericin B oral suspension in cancer patients with mucositis.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Candidiasis | 2002 |
10 other studies available for fluconazole and Cancer of Head
| Article | Year |
|---|---|
Molecular mechanisms of azole resistance in Candida glabrata isolated from oropharyngeal candidiasis in head and neck cancer patients.
Topics: Antifungal Agents; Azoles; Candida glabrata; Candidiasis, Oral; Drug Resistance, Fungal; Fluconazole | 2023 |
Evaluation of saliva flow rates, Candida colonization and susceptibility of Candida strains after head and neck radiation.
Topics: Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Candida; Candida albicans; Colony | 2012 |
Comparison of antifungal susceptibilities to fluconazole and voriconazole of oral Candida glabrata isolates from head and neck radiation patients.
Topics: Antifungal Agents; Candida glabrata; Candidiasis, Oral; Fluconazole; Head and Neck Neoplasms; Humans | 2004 |
Effect of fluconazole antifungal prophylaxis on oral mucositis in head and neck cancer patients receiving radiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Candidiasis, Oral; Drug Resistance, Fungal; Femal | 2006 |
[Antifugal susceptibility testing and antifugal traditional Chinese medicines screening of oral Candida isolated from head and neck cancer patients treated with radiotherapy or chemotherapy].
Topics: Antifungal Agents; Candida; Candida albicans; Candidiasis, Oral; Fluconazole; Head and Neck Neoplasm | 2006 |
Antifungal susceptibility testing of micafungin against Candida glabrata isolates.
Topics: Antifungal Agents; Candida glabrata; Drug Resistance, Fungal; Echinocandins; Fluconazole; Head and N | 2008 |
Influence of local radiotherapy on penetration of fluconazole into human saliva.
Topics: Administration, Oral; Adult; Female; Fluconazole; Head and Neck Neoplasms; Humans; Male; Middle Aged | 1993 |
Epidemiology of oropharyngeal Candida colonization and infection in patients receiving radiation for head and neck cancer.
Topics: Antifungal Agents; Candida; Candidiasis, Oral; Culture Media; Fluconazole; Head and Neck Neoplasms; | 1999 |
Candida dubliniensis in radiation-induced oropharyngeal candidiasis.
Topics: Adult; Antifungal Agents; Candida; Candida albicans; Candidiasis; Candidiasis, Oral; Carcinoma, Squa | 2001 |
Candida glabrata oropharyngeal candidiasis in patients receiving radiation treatment for head and neck cancer.
Topics: Adult; Antifungal Agents; Candida; Candidiasis; Fluconazole; Head and Neck Neoplasms; Humans; Male; | 2002 |