fluconazole has been researched along with Burns in 14 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacokinetic (PK) property of fluconazole might be significantly altered in major burn patients by medical interventions and physiologic changes." | 5.39 | Population pharmacokinetic analysis of fluconazole to predict therapeutic outcome in burn patients with Candida infection. ( Han, S; Hong, T; Hur, J; Jeon, S; Kim, J; Lee, J; Song, W; Woo, H; Yim, DS; Yim, H, 2013) |
| "The pharmacokinetics of fluconazole in nine adult patients with severe (30 to 95% total body surface area) burns were studied." | 5.08 | Fluconazole pharmacokinetics in burn patients. ( Boucher, BA; Canada, TW; Hanes, SD; Herring, VL; Hess, MM; Hickerson, WL; King, SR; Wandschneider, HL, 1998) |
| "Although there are many potential changes of pharmacokinetic parameters in patients with thermal injury, obesity or septicemia, data about the actual effect on pharmacokinetics and clinical efficacy of fluconazole are very limited." | 4.80 | Special pharmacokinetics of fluconazole in septic, obese and burn patients. ( Penk, A; Pittrow, L, 1999) |
| "Amphotericin B was prescribed therapeutically in 25 patients, in seven together with fluconazole." | 2.68 | Management of candida septicaemia in a regional burn unit. ( Belcher, K; Law, EJ; Still, JM, 1995) |
| "Fluconazole has been shown effective as prophylaxis of candidosis including in patients undergoing bone marrow transplantation as well as in treatment of oropharyngeal candidosis and for candidaemia occurring in non-neutropenic patients." | 2.39 | [Therapy of systemic candidiasis]. ( Meunier, F, 1994) |
| "The pharmacokinetic (PK) property of fluconazole might be significantly altered in major burn patients by medical interventions and physiologic changes." | 1.39 | Population pharmacokinetic analysis of fluconazole to predict therapeutic outcome in burn patients with Candida infection. ( Han, S; Hong, T; Hur, J; Jeon, S; Kim, J; Lee, J; Song, W; Woo, H; Yim, DS; Yim, H, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Rahimi, H | 1 |
| Roudbarmohammadi, S | 1 |
| Delavari H, H | 1 |
| Roudbary, M | 1 |
| Sinh, CT | 1 |
| Loi, CB | 1 |
| Minh, NTN | 1 |
| Lam, NN | 1 |
| Quang, DX | 1 |
| Quyet, D | 1 |
| Anh, DN | 1 |
| Hien, TTT | 1 |
| Su, HX | 1 |
| Tran-Anh, L | 1 |
| Santos, SR | 1 |
| Campos, EV | 1 |
| Sanches, C | 1 |
| Gomez, DS | 1 |
| Ferreira, MC | 1 |
| Han, S | 1 |
| Kim, J | 1 |
| Yim, H | 1 |
| Hur, J | 1 |
| Song, W | 1 |
| Lee, J | 1 |
| Jeon, S | 1 |
| Hong, T | 1 |
| Woo, H | 1 |
| Yim, DS | 1 |
| Lattif, AA | 1 |
| Prasad, R | 1 |
| Banerjee, U | 1 |
| Gupta, N | 1 |
| Mohammad, S | 1 |
| Baquer, NZ | 1 |
| Meunier, F | 1 |
| Still, JM | 2 |
| Law, EJ | 2 |
| Belcher, KE | 1 |
| Spencer, SA | 1 |
| Dubé, MP | 1 |
| Heseltine, PN | 1 |
| Rinaldi, MG | 1 |
| Evans, S | 1 |
| Zawacki, B | 1 |
| Belcher, K | 1 |
| Boucher, BA | 1 |
| King, SR | 1 |
| Wandschneider, HL | 1 |
| Hickerson, WL | 1 |
| Hanes, SD | 1 |
| Herring, VL | 1 |
| Canada, TW | 1 |
| Hess, MM | 1 |
| Rayatt, S | 1 |
| Wienbren, M | 1 |
| Clarke, J | 1 |
| Cawley, MJ | 1 |
| Braxton, GR | 1 |
| Haith, LR | 1 |
| Reilly, KJ | 1 |
| Guilday, RE | 1 |
| Patton, ML | 1 |
| Pittrow, L | 1 |
| Penk, A | 1 |
| Wilson, DC | 1 |
3 reviews available for fluconazole and Burns
| Article | Year |
|---|---|
[Therapy of systemic candidiasis].
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Burns; Candidiasis; Flucon | 1994 |
Trichosporon beigelii infection: experience in a regional burn center.
Topics: Adult; Amphotericin B; Antifungal Agents; Burns; Catheters, Indwelling; Drug Resistance, Microbial; | 2000 |
Special pharmacokinetics of fluconazole in septic, obese and burn patients.
Topics: Adult; Antifungal Agents; Burns; Fluconazole; Humans; Male; Mycoses; Obesity; Sepsis | 1999 |
2 trials available for fluconazole and Burns
| Article | Year |
|---|---|
Management of candida septicaemia in a regional burn unit.
Topics: Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Burn Units; Burns; Candidiasis; Child; F | 1995 |
Fluconazole pharmacokinetics in burn patients.
Topics: Adult; Aged; Antifungal Agents; Area Under Curve; Burns; Chromatography, High Pressure Liquid; Doubl | 1998 |
9 other studies available for fluconazole and Burns
| Article | Year |
|---|---|
Antifungal effects of indolicidin-conjugated gold nanoparticles against fluconazole-resistant strains of
Topics: Animals; Antifungal Agents; Antimicrobial Cationic Peptides; Burns; Candida albicans; Cell Death; Dr | 2019 |
Species Distribution and Antifungal Susceptibility Pattern of Candida Recovered from Intensive Care Unit Patients, Vietnam National Hospital of Burn (2017-2019).
Topics: Antifungal Agents; Burns; Candida; Candidiasis, Invasive; Drug Resistance, Fungal; Fluconazole; Hosp | 2021 |
Fluconazole plasma concentration measurement by liquid chromatography for drug monitoring of burn patients.
Topics: Adult; Antifungal Agents; Burns; Chromatography, High Pressure Liquid; Drug Monitoring; Fluconazole; | 2010 |
Population pharmacokinetic analysis of fluconazole to predict therapeutic outcome in burn patients with Candida infection.
Topics: Adult; Aged; Aged, 80 and over; Antifungal Agents; Burns; Candida; Candidiasis; Female; Fluconazole; | 2013 |
The glyoxylate cycle enzyme activities in the pathogenic isolates of Candida albicans obtained from HIV/AIDS, diabetic and burn patients.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Burns; Candida albicans; Candidiasis; Citr | 2006 |
A comparison of susceptibility to five antifungal agents of yeast cultures from burn patients.
Topics: Amphotericin B; Antifungal Agents; Burns; Candida; Drug Resistance, Microbial; Fluconazole; Flucytos | 1995 |
Fungemia and colonization with nystatin-resistant Candida rugosa in a burn unit.
Topics: Amphotericin B; Burn Units; Burns; Candida; Candidiasis; Case-Control Studies; Cross Infection; Fluc | 1994 |
Fluconazole use in burns patients.
Topics: Adolescent; Antifungal Agents; Burns; Candidiasis; Female; Fluconazole; Humans | 2000 |
Fluconazole failure in a child with burns and candidemia.
Topics: Amphotericin B; Burns; Candidiasis; Fluconazole; Humans; Infant; Male | 1992 |