Page last updated: 2024-10-27

fluconazole and Bleeding

fluconazole has been researched along with Bleeding in 5 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Research Excerpts

ExcerptRelevanceReference
"Bleeding safety in relation to use of systemic fluconazole and topical azoles among patients with atrial fibrillation treated with apixaban, rivaroxaban, or dabigatran is insufficiently explored, despite clinical relevance and several reports suggesting associations."8.12Bleeding Risk Following Systemic Fluconazole or Topical Azoles in Patients with Atrial Fibrillation on Apixaban, Rivaroxaban, or Dabigatran. ( Blanche, P; Gislason, GH; Hansen, ML; Holt, A; Jensen, MH; Lamberts, M; McGettigan, P; Nouhravesh, N; Rasmussen, PV; Schjerning, AM; Schou, M; Strange, JE; Torp-Pedersen, C, 2022)
" Metronidazole and fluconazole inhibit the metabolism of warfarin by blocking cytochrome P-450 2C9 (CYP-2C9), the major metabolic pathway of warfarin, with the end result being dramatic increases in patients' international normalized ratios (INRs) and potentially fatal bleeding."4.91Three Serious Drug Interactions that Every Dentist Should Know About. ( Hersh, EV; Moore, PA, 2015)
"Bleeding safety in relation to use of systemic fluconazole and topical azoles among patients with atrial fibrillation treated with apixaban, rivaroxaban, or dabigatran is insufficiently explored, despite clinical relevance and several reports suggesting associations."4.12Bleeding Risk Following Systemic Fluconazole or Topical Azoles in Patients with Atrial Fibrillation on Apixaban, Rivaroxaban, or Dabigatran. ( Blanche, P; Gislason, GH; Hansen, ML; Holt, A; Jensen, MH; Lamberts, M; McGettigan, P; Nouhravesh, N; Rasmussen, PV; Schjerning, AM; Schou, M; Strange, JE; Torp-Pedersen, C, 2022)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Holt, A1
Strange, JE1
Rasmussen, PV1
Blanche, P1
Nouhravesh, N1
Jensen, MH1
Schjerning, AM1
Schou, M1
Torp-Pedersen, C1
Gislason, GH1
Hansen, ML1
McGettigan, P1
Lamberts, M1
Shimoda, T1
Watanabe, A1
Wasmann, R1
Brüggemann, R1
Hersh, EV1
Moore, PA1
Allegue, F1
de Lis, MP1
Pérez-Alvarez, R1

Reviews

1 review available for fluconazole and Bleeding

ArticleYear
Three Serious Drug Interactions that Every Dentist Should Know About.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2015, Volume: 36, Issue:6

    Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Bradycardia; Cytochrome P-450

2015

Other Studies

4 other studies available for fluconazole and Bleeding

ArticleYear
Bleeding Risk Following Systemic Fluconazole or Topical Azoles in Patients with Atrial Fibrillation on Apixaban, Rivaroxaban, or Dabigatran.
    The American journal of medicine, 2022, Volume: 135, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Azoles; Cross-Over Studies; Dabigatran

2022
Apixaban for Atrial Fibrillation and Systemic Fluconazole: Bleeding Risk and Possible Preventative Measures.
    The American journal of medicine, 2022, Volume: 135, Issue:10

    Topics: Anticoagulants; Atrial Fibrillation; Factor Xa Inhibitors; Fluconazole; Hemorrhage; Humans; Pyrazole

2022
A stitch in time saves nine.
    Lancet (London, England), 2019, 05-11, Volume: 393, Issue:10184

    Topics: Fluconazole; Hemorrhage; Humans; Warfarin

2019
Primary cutaneous cryptococcosis presenting as a whitlow.
    Acta dermato-venereologica, 2007, Volume: 87, Issue:5

    Topics: Aged; Antifungal Agents; Cryptococcosis; Dermatomycoses; Fluconazole; Hand Dermatoses; Hemorrhage; H

2007