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fluconazole and Blastomycosis, North American

fluconazole has been researched along with Blastomycosis, North American in 28 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Research Excerpts

ExcerptRelevanceReference
"There are few clinical data concerning the use of fluconazole, a triazole antifungal agent with in vitro activity against Blastomyces dermatitidis, in the treatment of human blastomycosis."9.08Treatment of blastomycosis with fluconazole: a pilot study. The National Institute of Allergy and Infectious Diseases Mycoses Study Group. ( Bradsher, RW; Chapman, SW; Cloud, GA; Dine, A; Dismukes, WE; Kauffman, CA; Pappas, PG, 1995)
"Recent clinical data suggest that fluconazole at daily doses of 200 to 400 mg for at least 6 months is moderately effective therapy for non-life-threatening blastomycosis."9.08Treatment of blastomycosis with higher doses of fluconazole. The National Institute of Allergy and Infectious Diseases Mycoses Study Group. ( Bradsher, RW; Campbell, GD; Chapman, SW; Cloud, GA; Dismukes, WE; Kauffman, CA; Newman, C; Pappas, PG; Thomas, CJ, 1997)
"The authors present two cases of systemic blastomycosis successfully treated with fluconazole."7.68Case report: treatment of blastomycosis with fluconazole. ( Chin, TW; Fong, IW; Pearson, GJ, 1992)
"There are few clinical data concerning the use of fluconazole, a triazole antifungal agent with in vitro activity against Blastomyces dermatitidis, in the treatment of human blastomycosis."5.08Treatment of blastomycosis with fluconazole: a pilot study. The National Institute of Allergy and Infectious Diseases Mycoses Study Group. ( Bradsher, RW; Chapman, SW; Cloud, GA; Dine, A; Dismukes, WE; Kauffman, CA; Pappas, PG, 1995)
"Recent clinical data suggest that fluconazole at daily doses of 200 to 400 mg for at least 6 months is moderately effective therapy for non-life-threatening blastomycosis."5.08Treatment of blastomycosis with higher doses of fluconazole. The National Institute of Allergy and Infectious Diseases Mycoses Study Group. ( Bradsher, RW; Campbell, GD; Chapman, SW; Cloud, GA; Dismukes, WE; Kauffman, CA; Newman, C; Pappas, PG; Thomas, CJ, 1997)
" He was diagnosed with pulmonary blastomycosis by histological examination of lung biopsy and treated with fluconazole."3.85Probable pulmonary Blastomyomycocis in an immunocompetent person. ( Chen, H; Yu, L; Zhu, D, 2017)
" This case is of interest not only because of the exceptional location of the abscess in the brainstem, but also because of its treatment: this was the first case where the fluconazole-flucytosine combination was used against blastomycosis with fully satisfactory results after a 28-month follow-up."3.68[Blastomycosis localized in the brain stem]. ( Cosnefroy, JY; Dujardin, P; Ferrari, E; Gari-Toussaint, M; Lefichoux, Y; Michiels, JF; Paquis, P; Taillan, B, 1992)
"The authors present two cases of systemic blastomycosis successfully treated with fluconazole."3.68Case report: treatment of blastomycosis with fluconazole. ( Chin, TW; Fong, IW; Pearson, GJ, 1992)
"SCH 39304 was tested for treatment of acute or established murine pulmonary blastomycosis and was compared with ketoconazole and fluconazole in a model of acute infection."3.68SCH 39304 in the treatment of acute or established murine pulmonary blastomycosis. ( Brummer, E; Hanson, LH; Stevens, DA, 1991)
"Blastomycosis is a fungal infectious disease that can occur in both immunocompromised and immunocompetent populations endemic in North America, with no previous reports in Japan."1.91First Japanese case of disseminated blastomycosis imported from North America: A case report. ( Kakeya, H; Kamei, K; Kasamatsu, Y; Maruyama, A; Miyagawa-Hayashino, A; Nakagawa, Y; Ogura, Y; Shibuya, K; Takayama, K; Yaguchi, T; Yamada, T, 2023)
"To study the efficacy of micafungin combined with fluconazole in a murine model of disseminated blastoschizomycosis."1.35Micafungin combined with fluconazole, an effective therapy for murine blastoschizomycosis. ( Guarro, J; Mariné, M; Pastor, FJ; Rodríguez, MM; Serena, C, 2008)
"Blastomycosis was detected mainly in young, large-breed dogs."1.30Blastomycosis in dogs: 115 cases (1980-1995). ( Arceneaux, KA; Hosgood, G; Taboada, J, 1998)
" A D0870 dosage of 1 mg/kg QD was equivalent to fluconazole given at 100 mg/kg in reduction of lung burdens of B."1.29Activities of the triazole D0870 in vitro and against murine blastomycosis. ( Clemons, KV; Hanson, LH; Stevens, DA, 1993)
"The use of preventive treatment for fungal infections is cautioned due to the possibility of resistance to treatment."1.29Fungal infection overview. ( , 1995)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's14 (50.00)18.2507
2000's6 (21.43)29.6817
2010's5 (17.86)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Ogura, Y1
Yaguchi, T1
Kasamatsu, Y1
Nakagawa, Y1
Yamada, T1
Maruyama, A1
Miyagawa-Hayashino, A1
Takayama, K1
Shibuya, K1
Kakeya, H1
Kamei, K1
Yetmar, ZA1
Cano Cevallos, E1
Pritt, B1
DeSimone, DC1
Zhu, D1
Chen, H1
Yu, L1
Ergin, G1
Deger, SM1
Guz, G1
Houseright, RA1
Webb, JL1
Claus, KN1
Lahmiti, S1
Baki, S1
Clemans, JM1
Deitz, KL1
Riedesel, EA1
Yaeger, MJ1
Legendre, AM1
Brick, KE1
Agger, WA1
Rutland, BM1
Horenstein, MG1
Romano, A1
Giordano, S1
Di Carlo, P1
Abbagnato, L1
Sapuppo, F1
Lazzaro, G1
Tetamo, R1
Titone, L1
Gilor, C1
Graves, TK1
Barger, AM1
O'Dell-Anderson, K1
Serena, C1
Rodríguez, MM1
Mariné, M1
Pastor, FJ1
Guarro, J1
Pappas, PG2
Bradsher, RW2
Chapman, SW2
Kauffman, CA2
Dine, A1
Cloud, GA2
Dismukes, WE2
Clemons, KV1
Hanson, LH2
Stevens, DA2
Sugar, AM3
Liu, XP1
Thomas, CJ1
Campbell, GD1
Newman, C1
Berenguer Berenguer, J1
Arceneaux, KA1
Taboada, J1
Hosgood, G1
Briand, V1
Lortholary, O1
Schaberg, T1
Lode, H1
Taillan, B2
Ferrari, E2
Cosnefroy, JY2
Gari-Toussaint, M2
Michiels, JF2
Paquis, P2
Lefichoux, Y2
Dujardin, P2
Pearson, GJ1
Chin, TW1
Fong, IW1
Brummer, E1
Picard, M1
Noble, L1
Lyman, CA1
Diamond, RD1

Reviews

2 reviews available for fluconazole and Blastomycosis, North American

ArticleYear
[Commonly used antifungal agents in the treatment of systemic mycoses].
    Revista clinica espanola, 1995, Volume: 195 Suppl 3

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Clinical Trials as Top

1995
[Therapy of pulmonary mycoses].
    Deutsche medizinische Wochenschrift (1946), 1992, Nov-06, Volume: 117, Issue:45

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Blastomy

1992

Trials

2 trials available for fluconazole and Blastomycosis, North American

ArticleYear
Treatment of blastomycosis with fluconazole: a pilot study. The National Institute of Allergy and Infectious Diseases Mycoses Study Group.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Aged; Blastomycosis; Female; Fluconazole; Humans; Male; Middle Aged; Pilot Projec

1995
Treatment of blastomycosis with higher doses of fluconazole. The National Institute of Allergy and Infectious Diseases Mycoses Study Group.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Aged; Antifungal Agents; Blastomycosis; Female; Fluconazole; Humans; Male; Middle

1997

Other Studies

24 other studies available for fluconazole and Blastomycosis, North American

ArticleYear
First Japanese case of disseminated blastomycosis imported from North America: A case report.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2023, Volume: 29, Issue:10

    Topics: Adult; Antifungal Agents; Blastomyces; Blastomycosis; East Asian People; Female; Fluconazole; Humans

2023
Disseminated Blastomycosis Presenting as Obstructive Renal Mass Treated With Fluconazole.
    The American journal of medicine, 2020, Volume: 133, Issue:7

    Topics: Aged; Antifungal Agents; Blastomycosis; Constriction, Pathologic; Fluconazole; Humans; Image-Guided

2020
Probable pulmonary Blastomyomycocis in an immunocompetent person.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2017, Volume: 59

    Topics: Adult; Antifungal Agents; Biopsy; Blastomycosis; China; Fluconazole; Humans; Immunocompetence; Male;

2017
Successful Treatment of Cutaneous Blastomycosis in a Renal Transplant Patient With BK Virus Infection: A Case Report.
    Transplantation proceedings, 2019, Volume: 51, Issue:2

    Topics: Amphotericin B; Antifungal Agents; BK Virus; Blastomycosis; Coinfection; Fluconazole; Humans; Immuno

2019
Pathology in Practice. Blastomycosis in an indoor-only cat.
    Journal of the American Veterinary Medical Association, 2015, Aug-15, Volume: 247, Issue:4

    Topics: Animals; Antifungal Agents; Blastomyces; Blastomycosis; Cat Diseases; Cats; Diagnosis, Differential;

2015
Thoracic blastomycosis from Morocco.
    TheScientificWorldJournal, 2009, Mar-31, Volume: 9

    Topics: Blastomycosis; Clothing; Commerce; Fluconazole; Humans; Lung Diseases, Fungal; Male; Morocco; Occupa

2009
Retroperitoneal pyogranulomatous and fibrosing inflammation secondary to fungal infections in two dogs.
    Journal of the American Veterinary Medical Association, 2011, Jan-15, Volume: 238, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Blastomyces; Blastomycosis; Dog Diseases; Dogs; D

2011
Successful treatment of brainstem blastomycosis with fluconazole.
    Clinical medicine & research, 2012, Volume: 10, Issue:2

    Topics: Adult; Antifungal Agents; Blastomyces; Blastomycosis; Brain Stem; Central Nervous System Fungal Infe

2012
A 53-year-old man with an anterior knee fungating mass. Cutaneous blastomycosis.
    Archives of pathology & laboratory medicine, 2005, Volume: 129, Issue:5

    Topics: Antifungal Agents; Blastomyces; Blastomycosis; Carcinoma, Squamous Cell; Dermatomycoses; Diagnosis,

2005
[Pulmonary infection caused by Blastoschizomices capitatus].
    Le infezioni in medicina, 2005, Volume: 13, Issue:3

    Topics: Aged; Amphotericin B; Antifungal Agents; Blastomyces; Blastomycosis; Fatal Outcome; Female; Fluconaz

2005
Clinical aspects of natural infection with Blastomyces dermatitidis in cats: 8 cases (1991-2005).
    Journal of the American Veterinary Medical Association, 2006, Jul-01, Volume: 229, Issue:1

    Topics: Animals; Antifungal Agents; Blastomyces; Blastomycosis; Cat Diseases; Cats; Diagnosis, Differential;

2006
Micafungin combined with fluconazole, an effective therapy for murine blastoschizomycosis.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:4

    Topics: Animals; Antifungal Agents; Blastomycosis; Colony Count, Microbial; Drug Therapy, Combination; Echin

2008
Activities of the triazole D0870 in vitro and against murine blastomycosis.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:5

    Topics: Animals; Antifungal Agents; Blastomyces; Blastomycosis; Fluconazole; Male; Mice; Microbial Sensitivi

1993
In vitro and in vivo activities of SCH 56592 against Blastomyces dermatitidis.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:5

    Topics: Amphotericin B; Animals; Antifungal Agents; Blastomyces; Blastomycosis; Drug Evaluation, Preclinical

1996
Systemic antifungal drugs.
    The Medical letter on drugs and therapeutics, 1997, Sep-12, Volume: 39, Issue:1009

    Topics: Amphotericin B; Anorexia; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidom

1997
Blastomycosis in dogs: 115 cases (1980-1995).
    Journal of the American Veterinary Medical Association, 1998, Sep-01, Volume: 213, Issue:5

    Topics: Age Distribution; Amphotericin B; Animals; Antibodies, Fungal; Antifungal Agents; Blastomyces; Blast

1998
Fungal infection overview.
    Treatment review, 1995, Issue:no 18

    Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Blastomycosis; Candidiasis

1995
[Endemic mycotic infections].
    La Revue du praticien, 2001, Apr-15, Volume: 51, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Blastomycosis; Cocc

2001
[Blastomycosis localized in the brain stem].
    Presse medicale (Paris, France : 1983), 1992, Feb-08, Volume: 21, Issue:5

    Topics: Adult; Blastomyces; Blastomycosis; Brain Abscess; Brain Stem; Drug Therapy, Combination; Fluconazole

1992
Favourable outcome of blastomycosis of the brain stem with fluconazole and flucytosine treatment.
    Annals of medicine, 1992, Volume: 24, Issue:1

    Topics: Administration, Oral; Adult; Blastomyces; Blastomycosis; Brain Stem; Drug Therapy, Combination; Ence

1992
Case report: treatment of blastomycosis with fluconazole.
    The American journal of the medical sciences, 1992, Volume: 303, Issue:5

    Topics: Adult; Blastomycosis; Fluconazole; Humans; Male; Middle Aged; Respiratory Tract Infections; Tomograp

1992
SCH 39304 in the treatment of acute or established murine pulmonary blastomycosis.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:4

    Topics: Animals; Antifungal Agents; Blastomycosis; Fluconazole; Ketoconazole; Lung Diseases; Mice; Mice, Inb

1991
Treatment of murine pulmonary blastomycosis with SCH 39304, a new triazole antifungal agent.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:5

    Topics: Amphotericin B; Animals; Antifungal Agents; Blastomycosis; Fluconazole; Lung; Lung Diseases, Fungal;

1990
Comparative activities of UK-49,858 and amphotericin B against Blastomyces dermatitidis infections in mice.
    Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:1

    Topics: Amphotericin B; Animals; Antifungal Agents; Blastomycosis; Fluconazole; Male; Mice; Mice, Inbred BAL

1986