Page last updated: 2024-10-27

fluconazole and Aging

fluconazole has been researched along with Aging in 4 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The pharmacokinetic properties of fluconazole were studied in more than 100 pediatric patients, including 12 premature neonates."1.29Pharmacokinetics of fluconazole in pediatric patients. ( Brammer, KW; Coates, PE, 1994)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wils, J1
Djerada, Z1
Roca, F1
Duflot, T1
Iacob, M1
Remy-Jouet, I1
Joannides, R1
Bellien, J1
Fucic, A1
Markovic, D1
Herceg, Z1
Gamulin, M1
Katic, J1
Stojkovic, R1
Ferencic, Z1
Mildner, B1
Jazbec, AM1
Dobranic, T1
Brammer, KW1
Coates, PE1
Dudley, MN1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pharmacokinetics of a Fluconazole Loading Dose in Infants and Toddlers[NCT00797420]Phase 113 participants (Actual)Interventional2008-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for fluconazole and Aging

ArticleYear
Clinical pharmacology of fluconazole.
    Pharmacotherapy, 1990, Volume: 10, Issue:6 ( Pt 3)

    Topics: Absorption; Aging; Bone Marrow Transplantation; Fluconazole; Humans; Kidney Diseases; Molecular Stru

1990

Other Studies

3 other studies available for fluconazole and Aging

ArticleYear
Alteration in the availability of epoxyeicosatrienoic acids contributes with NO to the development of endothelial dysfunction in conduit arteries during aging.
    Atherosclerosis, 2018, Volume: 275

    Topics: Adult; Age Factors; Aged; Aging; Cytochrome P-450 Enzyme Inhibitors; Eicosanoids; Endothelium, Vascu

2018
Developmental and transplacental genotoxicology: fluconazole.
    Mutation research, 2008, Nov-17, Volume: 657, Issue:1

    Topics: Aging; Animals; Female; Fluconazole; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Micronucleu

2008
Pharmacokinetics of fluconazole in pediatric patients.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1994, Volume: 13, Issue:4

    Topics: Administration, Oral; Adolescent; Aging; Body Weight; Child; Child, Preschool; Fluconazole; Humans;

1994