fluconazole has been researched along with Adrenal Insufficiency in 12 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Adrenal Insufficiency: Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 52-year-old man with well-controlled HIV infection taking ritonavir and increasing doses of inhaled fluticasone for chronic bronchitis developed thrush." | 7.78 | Role of fluconazole in a case of rapid onset ritonavir and inhaled fluticasone-associated secondary adrenal insufficiency. ( Maguire, JD; St Clair, K, 2012) |
| "Although fluconazole is the therapy of choice for patients in the intensive care setting with Candida infections, two patients with multiple organ failure who received high-dose fluconazole appeared to develop adrenal insufficiency." | 7.71 | Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients. ( Albert, SG; DeLeon, MJ; Silverberg, AB, 2001) |
| " In this study, adrenal function and signs and symptoms of adrenal insufficiency were prospectively assessed in children with acute lymphoblastic leukemia (ALL) after induction treatment including high-dose prednisone (PDN) or dexamethasone (DXM)." | 5.13 | Adrenal axis function after high-dose steroid therapy for childhood acute lymphoblastic leukemia. ( Barisone, E; Bertorello, N; Corrias, A; Einaudi, S; Farinasso, L; Masera, N; Pastore, G; Riva, F; Rizzari, C; Saracco, P; Villa, A, 2008) |
| "A 52-year-old man with well-controlled HIV infection taking ritonavir and increasing doses of inhaled fluticasone for chronic bronchitis developed thrush." | 3.78 | Role of fluconazole in a case of rapid onset ritonavir and inhaled fluticasone-associated secondary adrenal insufficiency. ( Maguire, JD; St Clair, K, 2012) |
| "Although fluconazole is the therapy of choice for patients in the intensive care setting with Candida infections, two patients with multiple organ failure who received high-dose fluconazole appeared to develop adrenal insufficiency." | 3.71 | Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients. ( Albert, SG; DeLeon, MJ; Silverberg, AB, 2001) |
| "Fluticasone was discontinued, and the patient's adrenal function normalized." | 1.37 | Rapid onset of iatrogenic adrenal insufficiency in a patient with cystic fibrosis-related liver disease treated with inhaled corticosteroids and a moderate CYP3A4 inhibitor. ( Britton, LJ; Gardner, J; Gutierrez, H; Hoover, WC; Jackson, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Freyer, CW | 1 |
| Loren, AW | 1 |
| Choo, KS | 1 |
| Yew, J | 1 |
| Tan, EJH | 1 |
| Puar, THK | 1 |
| Rensen, N | 1 |
| Gemke, RJ | 1 |
| van Dalen, EC | 1 |
| Rotteveel, J | 1 |
| Kaspers, GJ | 1 |
| Humbert, L | 1 |
| Cornu, M | 1 |
| Proust-Lemoine, E | 1 |
| Bayry, J | 1 |
| Wemeau, JL | 1 |
| Vantyghem, MC | 1 |
| Sendid, B | 1 |
| Hoover, WC | 1 |
| Britton, LJ | 1 |
| Gardner, J | 1 |
| Jackson, T | 1 |
| Gutierrez, H | 1 |
| St Clair, K | 1 |
| Maguire, JD | 1 |
| Huang, YW | 1 |
| Chang, CC | 1 |
| Sun, HY | 1 |
| Chen, MY | 1 |
| Hung, CC | 1 |
| Chang, SC | 1 |
| Santhana Krishnan, SG | 1 |
| Cobbs, RK | 1 |
| Einaudi, S | 1 |
| Bertorello, N | 1 |
| Masera, N | 1 |
| Farinasso, L | 1 |
| Barisone, E | 1 |
| Rizzari, C | 1 |
| Corrias, A | 1 |
| Villa, A | 1 |
| Riva, F | 1 |
| Saracco, P | 1 |
| Pastore, G | 1 |
| Shibata, S | 1 |
| Kami, M | 1 |
| Kanda, Y | 1 |
| Machida, U | 1 |
| Iwata, H | 1 |
| Kishi, Y | 1 |
| Takeshita, A | 1 |
| Miyakoshi, S | 1 |
| Ueyama, J | 1 |
| Morinaga, S | 1 |
| Mutou, Y | 1 |
| Albert, SG | 1 |
| DeLeon, MJ | 1 |
| Silverberg, AB | 1 |
| Gradon, JD | 1 |
| Sepkowitz, DV | 1 |
3 reviews available for fluconazole and Adrenal Insufficiency
| Article | Year |
|---|---|
Case Report: Hypercalcemia as a manifestation of acute adrenal crisis precipitated by fluconazole use, and a review of the literature.
Topics: Adrenal Insufficiency; Aged; Fluconazole; Humans; Hydrocortisone; Hypercalcemia; Male; Shock, Septic | 2023 |
Hypothalamic-pituitary-adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia.
Topics: Adrenal Insufficiency; Antineoplastic Agents, Hormonal; Child; Cohort Studies; Dexamethasone; Flucon | 2017 |
Chronic Mucocutaneous Candidiasis in Autoimmune Polyendocrine Syndrome Type 1.
Topics: Adrenal Insufficiency; AIRE Protein; Animals; Autoantibodies; Candida albicans; Candidiasis, Chronic | 2018 |
1 trial available for fluconazole and Adrenal Insufficiency
| Article | Year |
|---|---|
Adrenal axis function after high-dose steroid therapy for childhood acute lymphoblastic leukemia.
Topics: Adrenal Cortex; Adrenal Insufficiency; Adrenocorticotropic Hormone; Antineoplastic Combined Chemothe | 2008 |
8 other studies available for fluconazole and Adrenal Insufficiency
| Article | Year |
|---|---|
Fluconazole-Induced adrenal insufficiency following allogeneic hematopoietic cell transplant.
Topics: Adrenal Insufficiency; Antifungal Agents; Azoles; Fluconazole; Hematopoietic Stem Cell Transplantati | 2022 |
Rapid onset of iatrogenic adrenal insufficiency in a patient with cystic fibrosis-related liver disease treated with inhaled corticosteroids and a moderate CYP3A4 inhibitor.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenal Insufficiency; Androstadienes; Anti-Ast | 2011 |
Role of fluconazole in a case of rapid onset ritonavir and inhaled fluticasone-associated secondary adrenal insufficiency.
Topics: Adrenal Insufficiency; Androstadienes; Anti-HIV Agents; Anti-Inflammatory Agents; Bronchitis; Drug I | 2012 |
Primary adrenal insufficiency in patients with acquired immunodeficiency syndrome: report of four cases.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; Adult; Antifungal Agents; Fluconazole; Hu | 2004 |
Reversible acute adrenal insufficiency caused by fluconazole in a critically ill patient.
Topics: Acute Disease; Adrenal Insufficiency; Adult; Antifungal Agents; Critical Illness; Fluconazole; Human | 2006 |
Acute adrenal failure associated with fluconazole after administration of high-dose cyclophosphamide.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Antibiotic Prophylaxis; Antifungal Agents; Antin | 2001 |
Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Aged; Antifungal Agents; Candidiasis; Cosyntropi | 2001 |
Fluconazole-associated acute adrenal insufficiency.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adrenal Insufficiency; Adult; Fluconazole; Humans | 1991 |