fluconazole has been researched along with Adrenal Gland Hypofunction in 12 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 52-year-old man with well-controlled HIV infection taking ritonavir and increasing doses of inhaled fluticasone for chronic bronchitis developed thrush." | 7.78 | Role of fluconazole in a case of rapid onset ritonavir and inhaled fluticasone-associated secondary adrenal insufficiency. ( Maguire, JD; St Clair, K, 2012) |
| "Although fluconazole is the therapy of choice for patients in the intensive care setting with Candida infections, two patients with multiple organ failure who received high-dose fluconazole appeared to develop adrenal insufficiency." | 7.71 | Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients. ( Albert, SG; DeLeon, MJ; Silverberg, AB, 2001) |
| " In this study, adrenal function and signs and symptoms of adrenal insufficiency were prospectively assessed in children with acute lymphoblastic leukemia (ALL) after induction treatment including high-dose prednisone (PDN) or dexamethasone (DXM)." | 5.13 | Adrenal axis function after high-dose steroid therapy for childhood acute lymphoblastic leukemia. ( Barisone, E; Bertorello, N; Corrias, A; Einaudi, S; Farinasso, L; Masera, N; Pastore, G; Riva, F; Rizzari, C; Saracco, P; Villa, A, 2008) |
| "A 52-year-old man with well-controlled HIV infection taking ritonavir and increasing doses of inhaled fluticasone for chronic bronchitis developed thrush." | 3.78 | Role of fluconazole in a case of rapid onset ritonavir and inhaled fluticasone-associated secondary adrenal insufficiency. ( Maguire, JD; St Clair, K, 2012) |
| "Although fluconazole is the therapy of choice for patients in the intensive care setting with Candida infections, two patients with multiple organ failure who received high-dose fluconazole appeared to develop adrenal insufficiency." | 3.71 | Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients. ( Albert, SG; DeLeon, MJ; Silverberg, AB, 2001) |
| "Fluticasone was discontinued, and the patient's adrenal function normalized." | 1.37 | Rapid onset of iatrogenic adrenal insufficiency in a patient with cystic fibrosis-related liver disease treated with inhaled corticosteroids and a moderate CYP3A4 inhibitor. ( Britton, LJ; Gardner, J; Gutierrez, H; Hoover, WC; Jackson, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Freyer, CW | 1 |
| Loren, AW | 1 |
| Choo, KS | 1 |
| Yew, J | 1 |
| Tan, EJH | 1 |
| Puar, THK | 1 |
| Rensen, N | 1 |
| Gemke, RJ | 1 |
| van Dalen, EC | 1 |
| Rotteveel, J | 1 |
| Kaspers, GJ | 1 |
| Humbert, L | 1 |
| Cornu, M | 1 |
| Proust-Lemoine, E | 1 |
| Bayry, J | 1 |
| Wemeau, JL | 1 |
| Vantyghem, MC | 1 |
| Sendid, B | 1 |
| Hoover, WC | 1 |
| Britton, LJ | 1 |
| Gardner, J | 1 |
| Jackson, T | 1 |
| Gutierrez, H | 1 |
| St Clair, K | 1 |
| Maguire, JD | 1 |
| Huang, YW | 1 |
| Chang, CC | 1 |
| Sun, HY | 1 |
| Chen, MY | 1 |
| Hung, CC | 1 |
| Chang, SC | 1 |
| Santhana Krishnan, SG | 1 |
| Cobbs, RK | 1 |
| Einaudi, S | 1 |
| Bertorello, N | 1 |
| Masera, N | 1 |
| Farinasso, L | 1 |
| Barisone, E | 1 |
| Rizzari, C | 1 |
| Corrias, A | 1 |
| Villa, A | 1 |
| Riva, F | 1 |
| Saracco, P | 1 |
| Pastore, G | 1 |
| Shibata, S | 1 |
| Kami, M | 1 |
| Kanda, Y | 1 |
| Machida, U | 1 |
| Iwata, H | 1 |
| Kishi, Y | 1 |
| Takeshita, A | 1 |
| Miyakoshi, S | 1 |
| Ueyama, J | 1 |
| Morinaga, S | 1 |
| Mutou, Y | 1 |
| Albert, SG | 1 |
| DeLeon, MJ | 1 |
| Silverberg, AB | 1 |
| Gradon, JD | 1 |
| Sepkowitz, DV | 1 |
3 reviews available for fluconazole and Adrenal Gland Hypofunction
| Article | Year |
|---|---|
Case Report: Hypercalcemia as a manifestation of acute adrenal crisis precipitated by fluconazole use, and a review of the literature.
Topics: Adrenal Insufficiency; Aged; Fluconazole; Humans; Hydrocortisone; Hypercalcemia; Male; Shock, Septic | 2023 |
Hypothalamic-pituitary-adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia.
Topics: Adrenal Insufficiency; Antineoplastic Agents, Hormonal; Child; Cohort Studies; Dexamethasone; Flucon | 2017 |
Chronic Mucocutaneous Candidiasis in Autoimmune Polyendocrine Syndrome Type 1.
Topics: Adrenal Insufficiency; AIRE Protein; Animals; Autoantibodies; Candida albicans; Candidiasis, Chronic | 2018 |
1 trial available for fluconazole and Adrenal Gland Hypofunction
| Article | Year |
|---|---|
Adrenal axis function after high-dose steroid therapy for childhood acute lymphoblastic leukemia.
Topics: Adrenal Cortex; Adrenal Insufficiency; Adrenocorticotropic Hormone; Antineoplastic Combined Chemothe | 2008 |
8 other studies available for fluconazole and Adrenal Gland Hypofunction
| Article | Year |
|---|---|
Fluconazole-Induced adrenal insufficiency following allogeneic hematopoietic cell transplant.
Topics: Adrenal Insufficiency; Antifungal Agents; Azoles; Fluconazole; Hematopoietic Stem Cell Transplantati | 2022 |
Rapid onset of iatrogenic adrenal insufficiency in a patient with cystic fibrosis-related liver disease treated with inhaled corticosteroids and a moderate CYP3A4 inhibitor.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenal Insufficiency; Androstadienes; Anti-Ast | 2011 |
Role of fluconazole in a case of rapid onset ritonavir and inhaled fluticasone-associated secondary adrenal insufficiency.
Topics: Adrenal Insufficiency; Androstadienes; Anti-HIV Agents; Anti-Inflammatory Agents; Bronchitis; Drug I | 2012 |
Primary adrenal insufficiency in patients with acquired immunodeficiency syndrome: report of four cases.
Topics: Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; Adult; Antifungal Agents; Fluconazole; Hu | 2004 |
Reversible acute adrenal insufficiency caused by fluconazole in a critically ill patient.
Topics: Acute Disease; Adrenal Insufficiency; Adult; Antifungal Agents; Critical Illness; Fluconazole; Human | 2006 |
Acute adrenal failure associated with fluconazole after administration of high-dose cyclophosphamide.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Antibiotic Prophylaxis; Antifungal Agents; Antin | 2001 |
Possible association between high-dose fluconazole and adrenal insufficiency in critically ill patients.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Aged; Antifungal Agents; Candidiasis; Cosyntropi | 2001 |
Fluconazole-associated acute adrenal insufficiency.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adrenal Insufficiency; Adult; Fluconazole; Humans | 1991 |