fluconazole has been researched along with Acute Kidney Injury in 20 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reported here is the case of a 72-year-old man who was diagnosed with Candida glabrata prosthetic mitral valve endocarditis and treated successfully with fluconazole plus caspofungin after he refused and was determined unfit for surgery." | 8.82 | Candida glabrata prosthetic valve endocarditis treated successfully with fluconazole plus caspofungin without surgery: a case report and literature review. ( Athan, E; Hughes, A; Lye, DC; O'Brien, D, 2005) |
| "Fluconazole is a widely used antifungal agent in critically ill patients." | 5.42 | Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. ( Lipman, J; Peake, SL; Roberts, JA; Roberts, MS; Robertson, TA; Sinnollareddy, MG, 2015) |
| "Rhabdomyolysis is a potential adverse consequence of statin therapy." | 5.35 | Rhabdomyolysis induced by simvastatin-fluconazole combination. ( Abuzetun, JY; Hazin, R; Porter, J; Suker, M, 2008) |
| "Reported here is the case of a 72-year-old man who was diagnosed with Candida glabrata prosthetic mitral valve endocarditis and treated successfully with fluconazole plus caspofungin after he refused and was determined unfit for surgery." | 4.82 | Candida glabrata prosthetic valve endocarditis treated successfully with fluconazole plus caspofungin without surgery: a case report and literature review. ( Athan, E; Hughes, A; Lye, DC; O'Brien, D, 2005) |
| " The patient was initially treated with amphotericin B deoxycholate plus fluconazole for disseminated cryptococcosis, according to guideline recommendations." | 3.91 | Invasive fungal infection by Cryptococcus neoformans var. grubii with bone marrow and meningeal involvement in a HIV-infected patient: a case report. ( Bay, MB; de Oliveira, AL; Freire, MG; Gomes, RMODS; Soares, RDA; Theodoro, RC; Vechi, HT, 2019) |
| "Fluconazole plasma levels were determined to evaluate whether this dosage is adequate to reach the advised fluconazole levels." | 2.72 | Fluconazole dosing in continuous veno-venous haemofiltration (CVVHF): need for a high daily dose of 800 mg. ( Bergner, R; Haefeli, WE; Henrich, DM; Hoffmann, M; Mikus, G; Riedel, KD; Uppenkamp, M; Walter-Sack, I, 2006) |
| "54-1) and the elimination half-life (t1/2) was 14." | 2.69 | Influence of continuous veno-venous haemodiafiltration and continuous veno-venous haemofiltration on the pharmacokinetics of fluconazole. ( Bruch, HP; Iven, H; Martens, T; Muhl, E; Rob, P, 2000) |
| " and Cryptococcus neoformans at a dosage of up to 800 mg day-1." | 2.40 | Dosage adjustment of fluconazole during continuous renal replacement therapy (CAVH, CVVH, CAVHD, CVVHD). ( Penk, A; Pittrow, L, 1999) |
| "Neurologic adverse effects of triazole antifungal compounds used for the treatment of systemic and deep mycoses are relatively rare." | 1.62 | Acute fluconazole toxicity: a case presenting with protean manifestations including systemic and neurologic symptoms. ( Ergene, U; Eşkut, N; Gedizlioğlu, M; Özlü, C; Ünal, O, 2021) |
| "Exertional rhabdomyolysis is a common condition with potentially life-threatening consequences; early recognition can prevent severe downstream complications." | 1.51 | Exertional Rhabdomyolysis in a Long-Distance Migrant. ( Andreae, MC; Fernando, DB; McVane, BA; Strayer, RJ, 2019) |
| "Fluconazole is a renally-eliminated antifungal commonly used to treat Candida species infections." | 1.43 | Fluconazole dosing predictions in critically-ill patients receiving prolonged intermittent renal replacement therapy: a Monte Carlo simulation approach. ( Gharibian, KN; Mueller, BA, 2016) |
| "Fluconazole is a widely used antifungal agent in critically ill patients." | 1.42 | Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. ( Lipman, J; Peake, SL; Roberts, JA; Roberts, MS; Robertson, TA; Sinnollareddy, MG, 2015) |
| " The aim of this study was to assess whether appropriate dosage adjustments were made in hospitalized patients with renal impairment." | 1.42 | Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia. ( Getachew, H; Shibeshi, W; Tadesse, Y, 2015) |
| "Rhabdomyolysis is a potential adverse consequence of statin therapy." | 1.35 | Rhabdomyolysis induced by simvastatin-fluconazole combination. ( Abuzetun, JY; Hazin, R; Porter, J; Suker, M, 2008) |
| "Fluconazole (FLCZ) is an antifungal agent that is efficacious in the treatment of fungal peritonitis." | 1.33 | Pharmacokinetics of fluconazole and fosfluconazole after intraperitoneal administration to peritoneal dialysis rats. ( Aoyama, T; Hatta, S; Kimura, K; Masuhara, K; Matsumoto, Y; Ogata, K; Shima, Y; Shimizu, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eşkut, N | 1 |
| Gedizlioğlu, M | 1 |
| Ünal, O | 1 |
| Özlü, C | 1 |
| Ergene, U | 1 |
| Vechi, HT | 1 |
| Theodoro, RC | 1 |
| de Oliveira, AL | 1 |
| Gomes, RMODS | 1 |
| Soares, RDA | 1 |
| Freire, MG | 1 |
| Bay, MB | 1 |
| McVane, BA | 1 |
| Andreae, MC | 1 |
| Fernando, DB | 1 |
| Strayer, RJ | 1 |
| Hernández-Torres, A | 1 |
| García-Vázquez, E | 1 |
| Laso-Ortiz, A | 1 |
| Herrero-Martínez, JA | 1 |
| Gómez-Gómez, J | 1 |
| Jakubowska, A | 1 |
| Kiliś-Pstrusińska, K | 1 |
| Pukajło-Marczyk, A | 1 |
| Samir, S | 1 |
| Bagłaj, M | 1 |
| Zwolińska, D | 1 |
| Sinnollareddy, MG | 1 |
| Roberts, MS | 1 |
| Lipman, J | 1 |
| Robertson, TA | 1 |
| Peake, SL | 1 |
| Roberts, JA | 1 |
| Getachew, H | 1 |
| Tadesse, Y | 1 |
| Shibeshi, W | 1 |
| Gharibian, KN | 1 |
| Mueller, BA | 1 |
| Mitha, M | 1 |
| Naicker, P | 1 |
| Mahida, P | 1 |
| Lye, DC | 1 |
| Hughes, A | 1 |
| O'Brien, D | 1 |
| Athan, E | 1 |
| Bergner, R | 1 |
| Hoffmann, M | 1 |
| Riedel, KD | 1 |
| Mikus, G | 1 |
| Henrich, DM | 1 |
| Haefeli, WE | 1 |
| Uppenkamp, M | 1 |
| Walter-Sack, I | 1 |
| Aoyama, T | 1 |
| Ogata, K | 1 |
| Shimizu, M | 1 |
| Hatta, S | 1 |
| Masuhara, K | 1 |
| Shima, Y | 1 |
| Kimura, K | 1 |
| Matsumoto, Y | 1 |
| Yarali, N | 1 |
| Tavil, B | 1 |
| Kara, A | 1 |
| Ozkasap, S | 1 |
| Tunç, B | 1 |
| Hazin, R | 1 |
| Abuzetun, JY | 1 |
| Suker, M | 1 |
| Porter, J | 1 |
| Filipowicz, J | 1 |
| Kozłowski, M | 1 |
| Irga, N | 1 |
| Szalewska, M | 1 |
| Zurowska, A | 1 |
| Slusarczyk, M | 1 |
| Valtonen, M | 1 |
| Tiula, E | 1 |
| Neuvonen, PJ | 1 |
| Pittrow, L | 2 |
| Penk, A | 2 |
| Muhl, E | 1 |
| Martens, T | 1 |
| Iven, H | 1 |
| Rob, P | 1 |
| Bruch, HP | 1 |
| Bergman, KA | 1 |
| Meis, JF | 1 |
| Horrevorts, AM | 1 |
| Monnens, L | 1 |
3 reviews available for fluconazole and Acute Kidney Injury
| Article | Year |
|---|---|
[Candida sp endocarditis. Experience in a third-level hospital and review of the literature].
Topics: Acute Kidney Injury; Adult; Aged; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Bacteria | 2013 |
Candida glabrata prosthetic valve endocarditis treated successfully with fluconazole plus caspofungin without surgery: a case report and literature review.
Topics: Acute Kidney Injury; Aged; Amphotericin B; Antifungal Agents; Candida glabrata; Candidiasis; Caspofu | 2005 |
Dosage adjustment of fluconazole during continuous renal replacement therapy (CAVH, CVVH, CAVHD, CVVHD).
Topics: Acute Kidney Injury; Antifungal Agents; Candidiasis; Fluconazole; Humans; Renal Replacement Therapy | 1999 |
3 trials available for fluconazole and Acute Kidney Injury
| Article | Year |
|---|---|
Fluconazole dosing in continuous veno-venous haemofiltration (CVVHF): need for a high daily dose of 800 mg.
Topics: Acute Kidney Injury; Antifungal Agents; Candida glabrata; Candidiasis; Cross-Sectional Studies; Fluc | 2006 |
Effect of continuous venovenous haemofiltration and haemodiafiltration on the elimination of fluconazole in patients with acute renal failure.
Topics: Acute Kidney Injury; Adult; Aged; Antifungal Agents; Area Under Curve; Female; Fluconazole; Half-Lif | 1997 |
Influence of continuous veno-venous haemodiafiltration and continuous veno-venous haemofiltration on the pharmacokinetics of fluconazole.
Topics: Acute Kidney Injury; Aged; Antifungal Agents; Area Under Curve; Bronchoalveolar Lavage Fluid; Candid | 2000 |
14 other studies available for fluconazole and Acute Kidney Injury
| Article | Year |
|---|---|
Acute fluconazole toxicity: a case presenting with protean manifestations including systemic and neurologic symptoms.
Topics: Acute Kidney Injury; Antifungal Agents; Confusion; Drug-Related Side Effects and Adverse Reactions; | 2021 |
Invasive fungal infection by Cryptococcus neoformans var. grubii with bone marrow and meningeal involvement in a HIV-infected patient: a case report.
Topics: Acute Kidney Injury; Amphotericin B; Antifungal Agents; Bone Marrow; CD4-Positive T-Lymphocytes; Cer | 2019 |
Exertional Rhabdomyolysis in a Long-Distance Migrant.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Clindamycin; Creatine Kinase; Female; Fluconazole; Human | 2019 |
Fungal urinary tract infection complicated by acute kidney injury in an infant with intestino-vesical fistula.
Topics: Acute Kidney Injury; Bacterial Infections; Fluconazole; Humans; Infant; Injections, Intravenous; Int | 2013 |
Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration.
Topics: Acute Kidney Injury; Aged; Antifungal Agents; Fluconazole; Humans; Middle Aged; Prospective Studies; | 2015 |
Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Arrhythmia Agents | 2015 |
Fluconazole dosing predictions in critically-ill patients receiving prolonged intermittent renal replacement therapy: a Monte Carlo simulation approach.
Topics: Acute Kidney Injury; Antifungal Agents; Area Under Curve; Candidiasis; Computer Simulation; Critical | 2016 |
Disseminated Cryptococcosis in an HIV-negative patient in South Africa: the elusive differential diagnosis.
Topics: Acute Kidney Injury; Adult; Amphotericin B; Antifungal Agents; Brain; Cryptococcosis; Cryptococcus n | 2010 |
Pharmacokinetics of fluconazole and fosfluconazole after intraperitoneal administration to peritoneal dialysis rats.
Topics: Acute Kidney Injury; Algorithms; Alkaline Phosphatase; Animals; Antifungal Agents; Area Under Curve; | 2005 |
Acute renal failure during ATRA treatment.
Topics: Acute Kidney Injury; Adolescent; Antifungal Agents; Antineoplastic Agents; Female; Fluconazole; Huma | 2008 |
Rhabdomyolysis induced by simvastatin-fluconazole combination.
Topics: Acute Kidney Injury; Aged; Antifungal Agents; Biomarkers; Creatine Kinase; Drug Interactions; Drug T | 2008 |
[Acute renal insufficiency during Candida albicans candidiasis in a 2-month old infant].
Topics: Acute Kidney Injury; Candidiasis; Fluconazole; Humans; Infant; Infusions, Intravenous; Male; Ultraso | 1997 |
[Pharmacokinetics and dosage of fluconazole in continuous hemofiltration (CAVH, CVVH) and hemodialysis (CAVHD, CVVHD)].
Topics: Acute Kidney Injury; Antifungal Agents; Candidiasis; Cryptococcosis; Drug Monitoring; Fluconazole; H | 1998 |
Acute renal failure in a neonate due to pelviureteric candidal bezoars successfully treated with long-term systemic fluconazole.
Topics: Acute Kidney Injury; Adult; Bezoars; Candidiasis; Female; Fluconazole; Humans; Infant, Newborn; Kidn | 1992 |