fluconazole has been researched along with Acute Disease in 76 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
Acute Disease: Disease having a short and relatively severe course.
Excerpt | Relevance | Reference |
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" We performed a randomized trial to compare itraconazole vs fluconazole, for prevention of IFIs in patients with acute leukemia (AL) and HSCT recipients." | 9.12 | A prospective randomized trial of itraconazole vs fluconazole for the prevention of fungal infections in patients with acute leukemia and hematopoietic stem cell transplant recipients. ( Akria, L; Benyamini, N; Dally, N; Dann, EJ; Fineman, R; Gorelik, A; Haddad, N; Oren, I; Rowe, JM; Sprecher, H; Tamir, A; Zuckerman, T, 2006) |
"To compare the efficacy and tolerability of fluconazole and oral amphotericin B in preventing fungal infection in neutropenic patients with acute leukemia." | 9.07 | Preventing fungal infection in neutropenic patients with acute leukemia: fluconazole compared with oral amphotericin B. ( Barbui, T; Bucaneve, G; Carotenuto, M; D'Antonio, D; Del Favero, A; Fasola, G; Liso, V; Mandelli, F; Martino, P; Menichetti, F; Micozzi, A; Nosari, AM; Ricci, P, 1994) |
"Prophylactic fluconazole prevents colonization and superficial infections by Candida species other than Candida krusei in patients undergoing chemotherapy for acute leukemia and is well tolerated." | 9.07 | Fluconazole prophylaxis of fungal infections in patients with acute leukemia. Results of a randomized placebo-controlled, double-blind, multicenter trial. ( Buell, DN; Chandrasekar, PH; Goodman, JL; Ho, WG; Horowitz, H; Islam, MZ; Lazarus, HM; Rosenfeld, CS; Shadduck, RK; Silber, JL; Winston, DJ, 1993) |
"Clinical, biological and histological manifestations were consistent with the diagnosis of acute generalized exanthematous pustulosis due to fluconazole." | 7.71 | [Acute generalized exanthematous pustulosis due to fluconazole]. ( Albès, B; Bazex, J; Belhadjali, H; Fabre, B, 2002) |
"To determine if fluconazole is effective treatment for hepatosplenic candidiasis that has not resolved with amphotericin B and flucytosine treatment." | 7.68 | Hepatosplenic candidiasis: successful treatment with fluconazole. ( Bradley, SF; Kauffman, CA; Ross, SC; Weber, DR, 1991) |
"To investigate the potential use of fluconazole for prevention and treatment of disseminated candidiasis in granulocytopenic patients, its in vivo antifungal activity was studied in three models of disseminated candidiasis in persistently granulocytopenic rabbits: acute, subacute, and chronic disseminated candidiasis." | 7.68 | Effects of preventive, early, and late antifungal chemotherapy with fluconazole in different granulocytopenic models of experimental disseminated candidiasis. ( Aoki, S; Bacher, J; Lee, J; Mechinaud, F; Pizzo, PA; Rubin, M; Walsh, TJ, 1990) |
"The clinical efficacy of fluconazole at doses of 100-400 mg daily given intravenously in the treatment of 6 cases of deep mycosis complicated with leukemia was evaluated." | 7.67 | [Clinical evaluation of fluconazole in the case of deep mycosis associated with leukemia]. ( Fukawa, H; Kodama, F; Maruta, A; Matsuzaki, M, 1989) |
"Fluconazole (FLU) is a new antifungal agent that has been used successfully to treat Candida infections and has modest activity against aspergillosis in animal models." | 6.67 | Antifungal prophylaxis during remission induction therapy for acute leukemia fluconazole versus intravenous amphotericin B. ( Anaissie, EJ; Bodey, GP; Elting, LS; Estey, E; Kantarjian, H; O'Brien, S, 1994) |
" We performed a randomized trial to compare itraconazole vs fluconazole, for prevention of IFIs in patients with acute leukemia (AL) and HSCT recipients." | 5.12 | A prospective randomized trial of itraconazole vs fluconazole for the prevention of fungal infections in patients with acute leukemia and hematopoietic stem cell transplant recipients. ( Akria, L; Benyamini, N; Dally, N; Dann, EJ; Fineman, R; Gorelik, A; Haddad, N; Oren, I; Rowe, JM; Sprecher, H; Tamir, A; Zuckerman, T, 2006) |
"To evaluate efficacy of ampicilline/sulbactame and fluconasole in the regimen of empirical antibiotic therapy in patients with acute leukemia." | 5.08 | [The empirical antibiotic therapy of patients with acute leukemias: the results of a multicenter study]. ( Filatov, LB; Iarikova, EN; Isaev, VG; Kaletin, GI; Kaporskaia, TS; Kliasova, GA; Klimko, NN; Lapin, VA; Medvedeva, NV; Parovichnikova, EN; Porokhona, ON; Pristupa, AS; Rekhtman, GB; Rossiev, VA; Savchenko, VG; Sharov, LN; Tolkacheva, TV; Tumakov, VA, 1998) |
"Prophylactic fluconazole prevents colonization and superficial infections by Candida species other than Candida krusei in patients undergoing chemotherapy for acute leukemia and is well tolerated." | 5.07 | Fluconazole prophylaxis of fungal infections in patients with acute leukemia. Results of a randomized placebo-controlled, double-blind, multicenter trial. ( Buell, DN; Chandrasekar, PH; Goodman, JL; Ho, WG; Horowitz, H; Islam, MZ; Lazarus, HM; Rosenfeld, CS; Shadduck, RK; Silber, JL; Winston, DJ, 1993) |
"To compare the efficacy and tolerability of fluconazole and oral amphotericin B in preventing fungal infection in neutropenic patients with acute leukemia." | 5.07 | Preventing fungal infection in neutropenic patients with acute leukemia: fluconazole compared with oral amphotericin B. ( Barbui, T; Bucaneve, G; Carotenuto, M; D'Antonio, D; Del Favero, A; Fasola, G; Liso, V; Mandelli, F; Martino, P; Menichetti, F; Micozzi, A; Nosari, AM; Ricci, P, 1994) |
" Our study was designed to assess the prevention of (1) staphylococcal and streptococcal infections using T when the central catheter is being placed, and (2) candida infection by the simultaneous use of a new anti-mycotic agent fluconazole (F) administered once-daily." | 5.06 | Prevention of gram-positive and Candida albicans infections using teicoplanin and fluconazole: a randomized study in neutropenic children. ( Arlet, G; Baruchel, A; Schaison, G, 1990) |
"Data from an 8-year period for 46 patients with severe acute pancreatitis and infected pancreatic necrosis were analyzed to determine the incidence of fungal infection, to identify risk factors for the development of fungal infection, and to assess the use of early fluconazole treatment." | 3.72 | Fungal infections in patients with severe acute pancreatitis and the use of prophylactic therapy. ( Blot, S; Colardyn, F; De Waele, JJ; Vogelaers, D, 2003) |
"Clinical, biological and histological manifestations were consistent with the diagnosis of acute generalized exanthematous pustulosis due to fluconazole." | 3.71 | [Acute generalized exanthematous pustulosis due to fluconazole]. ( Albès, B; Bazex, J; Belhadjali, H; Fabre, B, 2002) |
"Models of acute and chronic candidiasis were developed in Fischer 344 rats to evaluate the therapeutic efficacy of recombinant human macrophage colony-stimulating factor (rhM-CSF) alone and in combination with the antifungal agent fluconazole." | 3.69 | Antifungal activity of recombinant human macrophage colony-stimulating factor in models of acute and chronic candidiasis in the rat. ( Ando, D; Aukerman, SL; Fidler, JM; Vitt, CR; Zimmerman, RJ, 1994) |
"To determine if fluconazole is effective treatment for hepatosplenic candidiasis that has not resolved with amphotericin B and flucytosine treatment." | 3.68 | Hepatosplenic candidiasis: successful treatment with fluconazole. ( Bradley, SF; Kauffman, CA; Ross, SC; Weber, DR, 1991) |
"To investigate the potential use of fluconazole for prevention and treatment of disseminated candidiasis in granulocytopenic patients, its in vivo antifungal activity was studied in three models of disseminated candidiasis in persistently granulocytopenic rabbits: acute, subacute, and chronic disseminated candidiasis." | 3.68 | Effects of preventive, early, and late antifungal chemotherapy with fluconazole in different granulocytopenic models of experimental disseminated candidiasis. ( Aoki, S; Bacher, J; Lee, J; Mechinaud, F; Pizzo, PA; Rubin, M; Walsh, TJ, 1990) |
"The clinical efficacy of fluconazole at doses of 100-400 mg daily given intravenously in the treatment of 6 cases of deep mycosis complicated with leukemia was evaluated." | 3.67 | [Clinical evaluation of fluconazole in the case of deep mycosis associated with leukemia]. ( Fukawa, H; Kodama, F; Maruta, A; Matsuzaki, M, 1989) |
"Prophylactic dosage of antifungal agents (garlicin or low dosage fluconazole) can reduce the incidence of fungal infection in patients with SAP." | 2.71 | Prevention and therapy of fungal infection in severe acute pancreatitis: A prospective clinical study. ( Ai, ZL; Chen, JW; He, YM; Jiang, CQ; Lei, DX; Liu, ZS; Lv, XS; Qian, Q; Sun, Q; Yuan, YF, 2003) |
"Invasive fungal infections have increasingly become a matter of concern with regard to patients receiving intensive myelosuppressive therapy for hematologic malignancies." | 2.69 | Failure of fluconazole prophylaxis to reduce mortality or the requirement of systemic amphotericin B therapy during treatment for refractory acute myeloid leukemia: results of a prospective randomized phase III study. German AML Cooperative Group. ( Behre, G; Büchner, T; Eimermacher, H; Grote-Metke, A; Hiddemann, W; Kerkhoff, A; Kern, W; Kubica, U; Rudolf, T; Wörmann, B, 1998) |
"Fluconazole (FLU) is a new antifungal agent that has been used successfully to treat Candida infections and has modest activity against aspergillosis in animal models." | 2.67 | Antifungal prophylaxis during remission induction therapy for acute leukemia fluconazole versus intravenous amphotericin B. ( Anaissie, EJ; Bodey, GP; Elting, LS; Estey, E; Kantarjian, H; O'Brien, S, 1994) |
"Fluconazole was as effective as amphotericin B in preventing severe local and disseminated fungal disease (one documented and one highly suspected infection in each group of patients)." | 2.67 | A randomized study to compare oral fluconazole to amphotericin B in the prevention of fungal infections in patients with acute leukaemia. ( Branger, J; Dekker, AW; Rozenberg-Arska, M; Verhoef, J, 1991) |
"Cryptococcal meningitis is a severe fungal infection that occurs primarily in the setting of advanced immunodeficiency and remains a major cause of HIV-related deaths worldwide." | 2.58 | Treatment for HIV-associated cryptococcal meningitis. ( Eshun-Wilson, I; Ford, N; Jarvis, JN; Li, T; Rouse, B; Shapiro, AE; Tenforde, MW, 2018) |
"Most patients with sepsis or septic shock from a urinary source have complicated urinary tract infection." | 2.49 | Urinary tract infection. ( Nicolle, LE, 2013) |
"Vulvovaginal candidiasis is estimated to be the second most common cause of vaginitis after bacterial vaginosis." | 2.46 | Candidiasis (vulvovaginal). ( Spence, D, 2010) |
" The optimal dosing of AmB remains unclear." | 2.44 | Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings. ( Dedicoat, M; Dlamini, S; Paul, N; Sloan, D, 2008) |
"This study showed that a 10-day treatment with 20 mg/kg of fluconazole combined with sulfadiazine and pyrimethamine 1." | 1.62 | Determination of parasitic burden in the brain tissue of infected mice in acute toxoplasmosis after treatment by fluconazole combined with sulfadiazine and pyrimethamine. ( Anita, M; Hadi, M; Mohammad, JM; Reza, S; Sina, S; Soudabeh, E, 2021) |
"We experienced a rare case of acute pancreatitis caused by Candida infection." | 1.51 | A rare case of acute pancreatitis caused by Candida Albicans. ( Aono, M; Hiasa, Y; Hida, AI; Joko, K; Kumagi, T; Mashiba, T; Ochi, H; Oshiro, Y; Sunago, K; Takechi, S; Tange, K; Yokota, T, 2019) |
"Treatment with voriconazole was promptly started with success." | 1.43 | Acute isolated appendicitis due to Aspergillus carneus in a neutropenic child with acute myeloid leukemia. ( Bergami, E; Cavanna, C; Decembrino, N; Introzzi, F; Lallitto, F; Mangione, F; Marone, P; Tamarozzi, F; Tortorano, AM; Zecca, M, 2016) |
"Fluconazole is an important antifungal triazole used against others CNS related opportunistic pathogens such as Cryptococcus neoformans and Candida spp." | 1.39 | Toxoplasma gondii: the effect of fluconazole combined with sulfadiazine and pyrimethamine against acute toxoplasmosis in murine model. ( de Souza, W; Martins-Duarte, ÉS; Vommaro, RC, 2013) |
"The sinusitis was successfully treated with AmBisome, and surgical debridement." | 1.33 | Zygomycosis in the immunocompromised patient: a case report. ( Aoun, M; Beguin, H; Georgala, A; Husson, M; Meuleman, N; Nolard, N; Vekemans, M, 2006) |
"Fluconazole is a new oral absorbing triazolic antimycotic, inhibiting specifically the sterol synthesis of fungal membrane." | 1.28 | [The treatment of vaginal candidiasis with a single oral dose of fluconazole]. ( Karag'ozov, I; Katsarova, M; Zlatkov, V, 1991) |
" No significant adverse reactions nor abnormality in clinical laboratory tests related with the dosing of fluconazole were observed in any of the patients." | 1.28 | [A clinical evaluation of injectable fluconazole in the treatment of deep mycosis associated with hematological malignancy]. ( Hojo, H; Lin, KY; Torii, Y; Toyama, K; Tsuda, A; Yoshikawa, O, 1989) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (2.63) | 18.7374 |
1990's | 35 (46.05) | 18.2507 |
2000's | 22 (28.95) | 29.6817 |
2010's | 15 (19.74) | 24.3611 |
2020's | 2 (2.63) | 2.80 |
Authors | Studies |
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Donders, GG | 1 |
Grinceviciene, S | 1 |
Ruban, K | 1 |
Bellen, G | 1 |
Sina, S | 1 |
Mohammad, JM | 1 |
Reza, S | 1 |
Anita, M | 1 |
Soudabeh, E | 1 |
Hadi, M | 1 |
Jakkidi, M | 1 |
Basmadjian, C | 1 |
Roy, S | 1 |
Tenforde, MW | 1 |
Shapiro, AE | 1 |
Rouse, B | 1 |
Jarvis, JN | 1 |
Li, T | 1 |
Eshun-Wilson, I | 1 |
Ford, N | 1 |
Tange, K | 1 |
Yokota, T | 1 |
Sunago, K | 1 |
Aono, M | 1 |
Ochi, H | 1 |
Takechi, S | 1 |
Mashiba, T | 1 |
Hida, AI | 1 |
Oshiro, Y | 1 |
Joko, K | 1 |
Kumagi, T | 1 |
Hiasa, Y | 1 |
Nicolle, LE | 1 |
Coloma, PM | 1 |
Schuemie, MJ | 1 |
Trifirò, G | 1 |
Furlong, L | 1 |
van Mulligen, E | 1 |
Bauer-Mehren, A | 1 |
Avillach, P | 1 |
Kors, J | 1 |
Sanz, F | 1 |
Mestres, J | 1 |
Oliveira, JL | 1 |
Boyer, S | 1 |
Helgee, EA | 1 |
Molokhia, M | 1 |
Matthews, J | 1 |
Prieto-Merino, D | 1 |
Gini, R | 1 |
Herings, R | 1 |
Mazzaglia, G | 1 |
Picelli, G | 1 |
Scotti, L | 1 |
Pedersen, L | 1 |
van der Lei, J | 1 |
Sturkenboom, M | 1 |
Brissot, E | 1 |
Cahu, X | 1 |
Guillaume, T | 1 |
Delaunay, J | 1 |
Ayari, S | 1 |
Peterlin, P | 1 |
Le Bourgeois, A | 1 |
Harousseau, JL | 1 |
Milpied, N | 1 |
Bene, MC | 1 |
Moreau, P | 1 |
Mohty, M | 1 |
Chevallier, P | 1 |
Qiu, X | 1 |
Zhang, F | 1 |
Yang, X | 1 |
Wu, N | 1 |
Jiang, W | 1 |
Li, X | 2 |
Liu, Y | 1 |
Decembrino, N | 1 |
Zecca, M | 1 |
Tortorano, AM | 1 |
Mangione, F | 1 |
Lallitto, F | 1 |
Introzzi, F | 1 |
Bergami, E | 1 |
Marone, P | 1 |
Tamarozzi, F | 1 |
Cavanna, C | 1 |
Mohamed, AM | 1 |
Waheed, SA | 1 |
Mohamed, NM | 1 |
Clark, NM | 1 |
Sloan, D | 1 |
Dlamini, S | 1 |
Paul, N | 1 |
Dedicoat, M | 1 |
Pereira, GH | 1 |
Pádua, SS | 1 |
Park, MV | 1 |
Muller, RP | 1 |
Passos, RM | 1 |
Menezes, Y | 1 |
Spence, D | 1 |
Sekhavat, L | 1 |
Tabatabaii, A | 1 |
Tezerjani, FZ | 1 |
Malton, A | 1 |
DeFatta, RA | 1 |
Sataloff, RT | 1 |
Martins-Duarte, ÉS | 1 |
de Souza, W | 1 |
Vommaro, RC | 1 |
Pereira, O | 1 |
Figueira-Coelho, J | 1 |
Picado, B | 1 |
Costa, JN | 1 |
De Punzio, C | 1 |
Garutti, P | 1 |
Mollica, G | 1 |
Nappi, C | 1 |
Piccoli, R | 1 |
Genazzani, AR | 1 |
García de Hombre, AM | 1 |
Pineda Salguedo, A | 1 |
Myoken, Y | 1 |
Kyo, T | 1 |
Kohara, T | 1 |
Fujihara, M | 1 |
Sugata, T | 1 |
Mikami, Y | 1 |
De Waele, JJ | 1 |
Vogelaers, D | 1 |
Blot, S | 1 |
Colardyn, F | 1 |
He, YM | 1 |
Lv, XS | 1 |
Ai, ZL | 1 |
Liu, ZS | 1 |
Qian, Q | 1 |
Sun, Q | 1 |
Chen, JW | 1 |
Lei, DX | 1 |
Jiang, CQ | 1 |
Yuan, YF | 1 |
Allione, A | 1 |
Montanaro, M | 1 |
Marmont, F | 1 |
Pomero, F | 1 |
Porta, M | 1 |
Menichetti, F | 2 |
Buscemi, L | 1 |
Arechavala, A | 1 |
Negroni, R | 1 |
Hariya, A | 1 |
Naruse, Y | 1 |
Kobayashi, T | 1 |
Endo, M | 1 |
Ikeda, Y | 1 |
Yoshii, T | 1 |
Momomura, S | 1 |
Ishiwata, S | 1 |
Maehara, A | 1 |
Halliday, C | 1 |
Hoile, R | 1 |
Sorrell, T | 1 |
James, G | 1 |
Yadav, S | 1 |
Shaw, P | 1 |
Bleakley, M | 1 |
Bradstock, K | 1 |
Chen, S | 1 |
Even-Tov, E | 1 |
Niv, A | 1 |
Kraus, M | 1 |
Nash, M | 1 |
Oren, I | 1 |
Rowe, JM | 1 |
Sprecher, H | 1 |
Tamir, A | 1 |
Benyamini, N | 1 |
Akria, L | 1 |
Gorelik, A | 1 |
Dally, N | 1 |
Zuckerman, T | 1 |
Haddad, N | 1 |
Fineman, R | 1 |
Dann, EJ | 1 |
Georgala, A | 1 |
Vekemans, M | 1 |
Husson, M | 1 |
Meuleman, N | 1 |
Beguin, H | 1 |
Nolard, N | 1 |
Aoun, M | 1 |
Santhana Krishnan, SG | 1 |
Cobbs, RK | 1 |
Hara, S | 1 |
Yokote, T | 1 |
Oka, S | 1 |
Akioka, T | 1 |
Kobayashi, K | 1 |
Hirata, Y | 1 |
Miyoshi, T | 1 |
Tsuji, M | 1 |
Hanafusa, T | 1 |
Zar, T | 1 |
Zar, R | 1 |
Kaplan, AA | 1 |
Medlicott, SA | 1 |
Cox, H | 1 |
Dupre, M | 1 |
Lategan, J | 1 |
Auer, I | 1 |
Hollaar, G | 1 |
Debru, E | 1 |
Conly, J | 1 |
López Onrubia, P | 1 |
Bastida Vilá, MT | 1 |
Martínez Martínez, JA | 1 |
Ribas Montfort, J | 1 |
Jové Vidal, N | 1 |
Chmel, H | 1 |
Jacobson, MA | 1 |
Hanks, DK | 1 |
Ferrell, LD | 1 |
Ennis, DM | 1 |
Saag, MS | 2 |
Sobel, JD | 1 |
Brooker, D | 1 |
Stein, GE | 1 |
Thomason, JL | 1 |
Wermeling, DP | 1 |
Bradley, B | 1 |
Weinstein, L | 1 |
Chubachi, A | 1 |
Miura, I | 1 |
Ohshima, A | 1 |
Nishinari, T | 1 |
Nimura, T | 1 |
Niitsu, H | 1 |
Miura, AB | 1 |
Bridge, KS | 1 |
Goodpasture, HC | 1 |
Powderly, WG | 2 |
Cloud, GA | 1 |
Dismukes, WE | 1 |
Vitt, CR | 1 |
Fidler, JM | 1 |
Ando, D | 1 |
Zimmerman, RJ | 1 |
Aukerman, SL | 1 |
Fuller, JD | 1 |
Stanfield, LE | 1 |
Craven, DE | 1 |
Bodey, GP | 1 |
Anaissie, EJ | 1 |
Elting, LS | 1 |
Estey, E | 1 |
O'Brien, S | 1 |
Kantarjian, H | 1 |
Del Favero, A | 1 |
Martino, P | 1 |
Bucaneve, G | 1 |
Micozzi, A | 1 |
D'Antonio, D | 1 |
Ricci, P | 1 |
Carotenuto, M | 1 |
Liso, V | 1 |
Nosari, AM | 1 |
Barbui, T | 1 |
Fasola, G | 1 |
Mandelli, F | 1 |
Akiyama, H | 2 |
Mori, S | 1 |
Tanikawa, S | 1 |
Sakamaki, H | 2 |
Onozawa, Y | 2 |
Kliasova, GA | 2 |
Pavia, AT | 1 |
Riley, DK | 1 |
Loschiavo, F | 1 |
Ventura-Spagnolo, T | 1 |
Sessa, E | 1 |
Bramanti, P | 1 |
Winston, DJ | 1 |
Chandrasekar, PH | 1 |
Lazarus, HM | 1 |
Goodman, JL | 1 |
Silber, JL | 1 |
Horowitz, H | 1 |
Shadduck, RK | 1 |
Rosenfeld, CS | 1 |
Ho, WG | 1 |
Islam, MZ | 1 |
Buell, DN | 1 |
Guillaume, MP | 1 |
De Prez, C | 1 |
Cogan, E | 1 |
Schimkat, M | 1 |
Althaus, C | 1 |
Becker, K | 1 |
Sundmacher, R | 1 |
Horowitz, HW | 1 |
Holmgren, D | 1 |
Seiter, K | 1 |
Katz, BJ | 1 |
Scott, WE | 1 |
Folk, JC | 1 |
Kern, W | 1 |
Behre, G | 1 |
Rudolf, T | 1 |
Kerkhoff, A | 1 |
Grote-Metke, A | 1 |
Eimermacher, H | 1 |
Kubica, U | 1 |
Wörmann, B | 1 |
Büchner, T | 1 |
Hiddemann, W | 1 |
Savchenko, VG | 1 |
Parovichnikova, EN | 1 |
Isaev, VG | 1 |
Tolkacheva, TV | 1 |
Rossiev, VA | 1 |
Filatov, LB | 1 |
Tumakov, VA | 1 |
Iarikova, EN | 1 |
Rekhtman, GB | 1 |
Pristupa, AS | 1 |
Medvedeva, NV | 1 |
Sharov, LN | 1 |
Klimko, NN | 1 |
Porokhona, ON | 1 |
Lapin, VA | 1 |
Kaporskaia, TS | 1 |
Kaletin, GI | 1 |
Alonso, M | 1 |
García, F | 1 |
Mallolas, J | 1 |
Soriano, A | 1 |
Ortega, M | 1 |
Miró, JM | 1 |
Gatell, JM | 1 |
Soriano, E | 1 |
Young, GA | 1 |
Bosly, A | 1 |
Gibbs, DL | 1 |
Durrant, S | 1 |
Bruserud, O | 1 |
McKelvie, PA | 1 |
Wong, EY | 1 |
Chow, LP | 1 |
Hall, AJ | 1 |
Fabre, B | 1 |
Albès, B | 1 |
Belhadjali, H | 1 |
Bazex, J | 1 |
Bignardi, GE | 1 |
Savage, MA | 1 |
Coker, R | 1 |
Davis, SG | 1 |
Gradon, JD | 1 |
Sepkowitz, DV | 1 |
Kauffman, CA | 1 |
Bradley, SF | 1 |
Ross, SC | 1 |
Weber, DR | 1 |
Zlatkov, V | 1 |
Karag'ozov, I | 1 |
Katsarova, M | 1 |
Rozenberg-Arska, M | 1 |
Dekker, AW | 1 |
Branger, J | 1 |
Verhoef, J | 1 |
Walsh, TJ | 1 |
Aoki, S | 1 |
Mechinaud, F | 1 |
Bacher, J | 1 |
Lee, J | 1 |
Rubin, M | 1 |
Pizzo, PA | 1 |
Schaison, G | 1 |
Baruchel, A | 1 |
Arlet, G | 1 |
van Heusden, AM | 1 |
Merkus, HM | 1 |
Corbeij, RS | 1 |
Oosterbaan, HP | 1 |
Stoot, JE | 1 |
Ubachs, HM | 1 |
Verhoeff, A | 1 |
Maruta, A | 1 |
Matsuzaki, M | 1 |
Fukawa, H | 1 |
Kodama, F | 1 |
Toyama, K | 1 |
Lin, KY | 1 |
Hojo, H | 1 |
Tsuda, A | 1 |
Torii, Y | 1 |
Yoshikawa, O | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis[NCT00000708] | 120 participants | Interventional | Completed | ||||
Comparison of Fluconazole (UK-49,858) and Amphotericin B for Maintenance Treatment of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency Syndrome[NCT00001017] | Phase 3 | 330 participants | Interventional | Completed | |||
A Phase II Trial to Evaluate the Safety and Tolerability of Nebulised Amphotericin B Lipid Complex (ABELCET®) in the Prophylaxis of Invasive Pulmonary Aspergillosis During Prolonged Neutropenia in Paediatric Patients With Acute Leukaemia[NCT01615809] | Phase 2 | 32 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
ANTIVORIFUNGOL:Strategy of Antifungal Use in Oncohematological Neutropenic Patients. Use of Voriconazole as Early Treatment.[NCT00386802] | Phase 4 | 115 participants (Anticipated) | Interventional | 2006-08-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The incidence of invasive pulmonary aspergillosis during the Abelcet® prophylactic treatment period was assessed by the relation between the number of patients with invasive pulmonary aspergillosis and the number of paediatric patients on prophylaxis with Acute Leukaemia (AL) undergoing intensive chemotherapy. (NCT01615809)
Timeframe: at the Baseline visit (week 1) and at the end of the profilaxis treatment phase, up to 6 weeks
Intervention | participants (Number) |
---|---|
Amphotericin B (ABELCET®) | 3 |
Percentage of deaths related to Invasive Pulmonary Aspergillosis during the prophylactic treatment period with Abelcet® in paediatric patients with Acute Leukaemia undergoing intensive chemotherapy. (NCT01615809)
Timeframe: at the Baseline visit (week 1) and at the end of the profilaxis treatment phase, up to 6 weeks
Intervention | percentage of deaths (Number) |
---|---|
Amphotericin B (ABELCET®) | 0 |
is assessed by the proportion of patients who discontinue prophylactic treatment with Abelcet® due to an adverse event that is related or not to the study drug or for intolerability to it. The last week of treatment will have a different calendar for each participant, depending on the number of cicles needed by each patient (it has been anticipated up to 5 cicles of 2-6 weeks each). (NCT01615809)
Timeframe: at the Baseline visit (week 1) and during the Last week of treatment, up to 6 weeks
Intervention | participants (Number) |
---|---|
Amphotericin B (ABELCET®) | 0 |
7 reviews available for fluconazole and Acute Disease
Article | Year |
---|---|
Treatment for HIV-associated cryptococcal meningitis.
Topics: Acetazolamide; Acute Disease; Adult; Amphotericin B; Antifungal Agents; Developing Countries; Drug A | 2018 |
Urinary tract infection.
Topics: Acute Disease; Aminoglycosides; Amphotericin B; Anti-Infective Agents; Antifungal Agents; Catheters, | 2013 |
Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings.
Topics: Acetazolamide; Acute Disease; Adult; Amphotericin B; Antifungal Agents; Antihypertensive Agents; Dev | 2008 |
Candidiasis (vulvovaginal).
Topics: Acute Disease; Administration, Oral; Candida albicans; Candidiasis, Vulvovaginal; Evidence-Based Med | 2010 |
Cryptococcal meningitis in AIDS.
Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Carbon; Coloring Agents | 1993 |
Cryptococcal meningitis and AIDS.
Topics: Acute Disease; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Clinical Tr | 1993 |
Subacute mitochondrial liver disease in a patient with AIDS: possible relationship to prolonged fluconazole administration.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; AIDS-Related Opportunistic Infections; Ant | 1996 |
16 trials available for fluconazole and Acute Disease
Article | Year |
---|---|
Oral fluconazole 150 mg single dose versus intra-vaginal clotrimazole treatment of acute vulvovaginal candidiasis.
Topics: Acute Disease; Administration, Intravaginal; Administration, Oral; Adult; Antifungal Agents; Candidi | 2011 |
Fluconazole 150 mg single dose versus itraconazole 200 mg per day for 3 days in the treatment of acute vaginal candidiasis: a double-blind randomized study.
Topics: Acute Disease; Administration, Oral; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Double-Bli | 2003 |
Prevention and therapy of fungal infection in severe acute pancreatitis: A prospective clinical study.
Topics: Acute Disease; Adult; Aged; Allyl Compounds; Amphotericin B; Antifungal Agents; Disulfides; Female; | 2003 |
A prospective randomized trial of itraconazole vs fluconazole for the prevention of fungal infections in patients with acute leukemia and hematopoietic stem cell transplant recipients.
Topics: Acute Disease; Adolescent; Adult; Aged; Antifungal Agents; Aspergillosis; Drug Administration Schedu | 2006 |
Single oral dose fluconazole compared with conventional clotrimazole topical therapy of Candida vaginitis. Fluconazole Vaginitis Study Group.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Adolescent; Adult; Candidiasis, Vulvov | 1995 |
Measurement of cryptococcal antigen in serum and cerebrospinal fluid: value in the management of AIDS-associated cryptococcal meningitis.
Topics: Acute Disease; AIDS-Related Opportunistic Infections; Amphotericin B; Antigens, Fungal; Biomarkers; | 1994 |
Measurement of cryptococcal antigen in serum and cerebrospinal fluid: value in the management of AIDS-associated cryptococcal meningitis.
Topics: Acute Disease; AIDS-Related Opportunistic Infections; Amphotericin B; Antigens, Fungal; Biomarkers; | 1994 |
Measurement of cryptococcal antigen in serum and cerebrospinal fluid: value in the management of AIDS-associated cryptococcal meningitis.
Topics: Acute Disease; AIDS-Related Opportunistic Infections; Amphotericin B; Antigens, Fungal; Biomarkers; | 1994 |
Measurement of cryptococcal antigen in serum and cerebrospinal fluid: value in the management of AIDS-associated cryptococcal meningitis.
Topics: Acute Disease; AIDS-Related Opportunistic Infections; Amphotericin B; Antigens, Fungal; Biomarkers; | 1994 |
Antifungal prophylaxis during remission induction therapy for acute leukemia fluconazole versus intravenous amphotericin B.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amphotericin B; Blast Crisis; Female; Flu | 1994 |
Preventing fungal infection in neutropenic patients with acute leukemia: fluconazole compared with oral amphotericin B.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Amphotericin | 1994 |
Fluconazole prophylaxis of fungal infections in patients with acute leukemia. Results of a randomized placebo-controlled, double-blind, multicenter trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Fluconazole; | 1993 |
Stepdown single agent antibiotic therapy for the management of the high risk neutropenic adult with hematologic malignancies.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciproflo | 1996 |
Failure of fluconazole prophylaxis to reduce mortality or the requirement of systemic amphotericin B therapy during treatment for refractory acute myeloid leukemia: results of a prospective randomized phase III study. German AML Cooperative Group.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Amphotericin B; Antibiotic Prophylaxis | 1998 |
[The empirical antibiotic therapy of patients with acute leukemias: the results of a multicenter study].
Topics: Acute Disease; Adult; Ampicillin; Anti-Bacterial Agents; Cefoperazone; Cephalosporins; Drug Therapy, | 1998 |
A double-blind comparison of fluconazole and nystatin in the prevention of candidiasis in patients with leukaemia. Antifungal Prophylaxis Study Group.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; | 1999 |
A randomized study to compare oral fluconazole to amphotericin B in the prevention of fungal infections in patients with acute leukaemia.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Amphotericin B; Femal | 1991 |
Prevention of gram-positive and Candida albicans infections using teicoplanin and fluconazole: a randomized study in neutropenic children.
Topics: Acute Disease; Adolescent; Anti-Bacterial Agents; Bacterial Infections; Candidiasis; Child; Child, P | 1990 |
Single-dose oral fluconazole versus single-dose topical miconazole for the treatment of acute vulvovaginal candidosis.
Topics: Acute Disease; Administration, Intravaginal; Administration, Oral; Adult; Candidiasis, Vulvovaginal; | 1990 |
53 other studies available for fluconazole and Acute Disease
Article | Year |
---|---|
Vaginal pH and microbiota during fluconazole maintenance treatment for recurrent vulvovaginal candidosis (RVVC).
Topics: Acute Disease; Adolescent; Adult; Antifungal Agents; Bacteria; Candida; Candidiasis, Vulvovaginal; D | 2020 |
Determination of parasitic burden in the brain tissue of infected mice in acute toxoplasmosis after treatment by fluconazole combined with sulfadiazine and pyrimethamine.
Topics: 14-alpha Demethylase Inhibitors; Acute Disease; Animals; Antiprotozoal Agents; Brain; Disease Models | 2021 |
An illusion of septic shock: acute generalised exanthematous pustulosis with multiorgan dysfunction.
Topics: Acute Disease; Acute Generalized Exanthematous Pustulosis; Anti-Bacterial Agents; Anti-Inflammatory | 2017 |
A rare case of acute pancreatitis caused by Candida Albicans.
Topics: Abdominal Pain; Acute Disease; Antifungal Agents; Candida albicans; Candidiasis; Combined Modality T | 2019 |
Drug-induced acute myocardial infarction: identifying 'prime suspects' from electronic healthcare records-based surveillance system.
Topics: Acute Disease; Adverse Drug Reaction Reporting Systems; Azithromycin; Betamethasone; Cisapride; Domp | 2013 |
Initial fluconazole prophylaxis may not be required in adults with acute leukemia or myelodysplastic/myeloproliferative disorders after reduced intensity conditioning peripheral blood stem cell allogeneic transplantation.
Topics: Acute Disease; Adult; Aged; Chemoprevention; Female; Fluconazole; Humans; Leukemia; Male; Middle Age | 2015 |
Changes in the composition of intestinal fungi and their role in mice with dextran sulfate sodium-induced colitis.
Topics: Acute Disease; Animals; beta-Glucans; Colitis; Colon; Cytokines; Dextran Sulfate; Discriminant Analy | 2015 |
Acute isolated appendicitis due to Aspergillus carneus in a neutropenic child with acute myeloid leukemia.
Topics: Acute Disease; Acyclovir; Amphotericin B; Antifungal Agents; Appendicitis; Aspergillosis; Aspergillu | 2016 |
An 87-Year-Old Man with Acute Catastrophic Pneumonia.
Topics: Acute Disease; Aged, 80 and over; Anti-Bacterial Agents; Antifungal Agents; Burkholderia cepacia; Ca | 2016 |
Chronic meningitis by histoplasmosis: report of a child with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Amphotericin B; Antifungal Agents; Chronic Disease; Deoxycholic Acid; Dru | 2008 |
Acute candidal pharyngolaryngitis.
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Antifungal Agents; Candida; Candidiasis; Fluconazole; | 2012 |
[The Polish Gynecological Society Expert Committee recomendations regarding application of fluconazole in the treatment of vulvovaginal candidiasis].
Topics: Acute Disease; Administration, Topical; Antifungal Agents; Candida; Candidiasis, Vulvovaginal; Chron | 2012 |
Toxoplasma gondii: the effect of fluconazole combined with sulfadiazine and pyrimethamine against acute toxoplasmosis in murine model.
Topics: Acute Disease; Animals; Antifungal Agents; Antiprotozoal Agents; Cell Line; Cell Survival; Disease M | 2013 |
Black oesophagus.
Topics: Acute Disease; Alcoholism; Antifungal Agents; Candidiasis; Endoscopy, Digestive System; Esophageal S | 2013 |
[Acute obstructive nasal syndrome as expression of infectious mononucleosis. A case report].
Topics: Acute Disease; Adult; Antifungal Agents; Candida albicans; Candidiasis; Diagnosis, Differential; Flu | 2002 |
Breakthrough fungemia caused by azole-resistant Candida albicans in neutropenic patients with acute leukemia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Antineoplastic Age | 2003 |
Fungal infections in patients with severe acute pancreatitis and the use of prophylactic therapy.
Topics: Acute Disease; Anti-Bacterial Agents; Antifungal Agents; Candida albicans; Chemoprevention; Female; | 2003 |
Fungal endophthalmitis in acute leukaemia.
Topics: Acute Disease; Adult; Antifungal Agents; Endophthalmitis; Eye Infections, Fungal; Fluconazole; Human | 2004 |
How to improve the design of trials of antifungal prophylaxis among neutropenic adults with acute leukemia.
Topics: Acute Disease; Adult; Antifungal Agents; Clinical Trials as Topic; Fluconazole; Humans; Itraconazole | 2004 |
[Study of acute vulvovaginitis in sexually active adult women, with special reference to candidosis, in patients of the Francisco J. Muñiz Infectious Diseases Hospital].
Topics: Acute Disease; Adolescent; Adult; Argentina; Candida; Candidiasis, Vulvovaginal; Carrier State; Como | 2004 |
[Fungal endocarditis found at onset of lower limb acute aortic occlusion; report of a case].
Topics: Acute Disease; Antifungal Agents; Aortic Diseases; Arterial Occlusive Diseases; Candidiasis; Combine | 2005 |
Role of prospective screening of blood for invasive aspergillosis by polymerase chain reaction in febrile neutropenic recipients of haematopoietic stem cell transplants and patients with acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Antifungal Agents; Aspergillosis; Aspergillus; DNA, Fungal; Female | 2006 |
Candida parotitis with abscess formation.
Topics: Abscess; Acute Disease; Aged; Candida albicans; Candidiasis; Combined Modality Therapy; Contrast Med | 2006 |
Zygomycosis in the immunocompromised patient: a case report.
Topics: Absidia; Acute Disease; Aerosols; Amphotericin B; Amsacrine; Antibiotic Prophylaxis; Antifungal Agen | 2006 |
Reversible acute adrenal insufficiency caused by fluconazole in a critically ill patient.
Topics: Acute Disease; Adrenal Insufficiency; Adult; Antifungal Agents; Critical Illness; Fluconazole; Human | 2006 |
Endophthalmitis due to Trichosporon beigelii in acute leukemia.
Topics: Acute Disease; Adult; Amphotericin B; Antifungal Agents; Drug Resistance, Fungal; Endophthalmitis; F | 2007 |
Candidemia-induced acute interstitial nephritis.
Topics: Acute Disease; Administration, Oral; Adult; Antifungal Agents; Candidiasis; Caspofungin; Diagnosis, | 2007 |
Systemic illnesses unexpectedly presenting as acute appendicitis: case studies.
Topics: Acute Disease; Adult; Amphotericin B; Antifungal Agents; Appendicitis; Candidiasis; Female; Fluconaz | 2008 |
Acute cholecystitis and wound infection due to Candida albicans.
Topics: Acute Disease; Aged; Candidiasis; Cholecystectomy; Cholecystitis; Female; Fluconazole; Humans; Surgi | 1995 |
Fatal acute hepatic necrosis due to fluconazole.
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Cimetidine; Fatal Outcome; Fluconazole; Human | 1995 |
Fatal acute hepatic necrosis due to fluconazole.
Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Chemical and Drug Induced Liver Injury; | 1994 |
Risk factors for hepatosplenic abscesses in patients with acute leukemia receiving empiric azole treatment.
Topics: Abscess; Acute Disease; Adolescent; Adult; Aged; Candidiasis; Female; Fever; Fluconazole; Humans; Le | 1994 |
Disseminated histoplasmosis treated with fluconazole.
Topics: Acute Disease; Fluconazole; Histoplasmosis; Humans; Male; Middle Aged | 1994 |
Antifungal activity of recombinant human macrophage colony-stimulating factor in models of acute and chronic candidiasis in the rat.
Topics: Acute Disease; Animals; Candidiasis; Chronic Disease; Fluconazole; Leukocyte Count; Macrophage Colon | 1994 |
Rifabutin prophylaxis and uveitis.
Topics: Acute Disease; AIDS-Related Opportunistic Infections; Fluconazole; Humans; Male; Middle Aged; Mycoba | 1994 |
Prevention of invasive fungal infection during chemotherapy-induced neutropenia in patients with acute leukemia.
Topics: Acute Disease; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Amphoteric | 1994 |
[The use of diflucan in myelotoxic agranulocytosis].
Topics: Acute Disease; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; | 1993 |
Fluconazole prophylaxis in patients with leukemia.
Topics: Acute Disease; Candidiasis; Fluconazole; Humans; Leukemia | 1993 |
Fluconazole prophylaxis in patients with leukemia.
Topics: Acute Disease; Candidiasis; Fluconazole; Humans; Leukemia | 1993 |
Acute meningitis from Cryptococcus neoformans (Filobasidiella neoformans) in a patient suffering from AIDS. Report of a clinical case with a favourable outcome.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Cerebrospinal Fluid; Comorbidity; Cryptoco | 1993 |
Rifabutin-associated anterior uveitis in patients infected with human immunodeficiency virus.
Topics: Acute Disease; Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Ag | 1996 |
Acute histoplasmosis choroiditis in 2 immunocompetent brothers.
Topics: Acute Disease; Antibodies, Fungal; Antifungal Agents; Antigens, Fungal; Child, Preschool; Choroiditi | 1997 |
[Disseminated cryptococcosis in patients with AIDS. Prognostic factors of poor outcome].
Topics: Acute Disease; Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Amphotericin B; Analy | 1999 |
Effects of azoles on human acute myelogenous leukemia blasts and T lymphocytes derived from acute leukemia patients with chemotherapy-induced cytopenia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antifungal Agents; CD4-Positive T-Lymphocytes; CD8-Positive | 2001 |
Scedosporium endophthalmitis: two fatal disseminated cases of Scedosporium infection presenting with endophthalmitis.
Topics: Acute Disease; Adult; Amphotericin B; Antifungal Agents; Endophthalmitis; Eye Infections, Fungal; Fa | 2001 |
[Acute generalized exanthematous pustulosis due to fluconazole].
Topics: Acute Disease; Aged; Drug Eruptions; Exanthema; Female; Fluconazole; Humans; Skin Diseases, Vesiculo | 2002 |
Fluconazole and Candida krusei infections.
Topics: Acute Disease; Candidiasis; Drug Resistance, Microbial; Female; Fluconazole; Fungemia; Humans; Leuke | 1991 |
Fluconazole-associated acute adrenal insufficiency.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adrenal Insufficiency; Adult; Fluconazole; Humans | 1991 |
Hepatosplenic candidiasis: successful treatment with fluconazole.
Topics: Acute Disease; Adolescent; Adult; Amphotericin B; Candidiasis; Child; Child, Preschool; Fluconazole; | 1991 |
[The treatment of vaginal candidiasis with a single oral dose of fluconazole].
Topics: Acute Disease; Administration, Oral; Adult; Candidiasis, Vulvovaginal; Drug Evaluation; Female; Fluc | 1991 |
Effects of preventive, early, and late antifungal chemotherapy with fluconazole in different granulocytopenic models of experimental disseminated candidiasis.
Topics: Acute Disease; Agranulocytosis; Amphotericin B; Animals; Candidiasis; Chronic Disease; Disease Model | 1990 |
[Clinical evaluation of fluconazole in the case of deep mycosis associated with leukemia].
Topics: Acute Disease; Adolescent; Adult; Aged; Antifungal Agents; Candidiasis; Drug Evaluation; Drug Tolera | 1989 |
[A clinical evaluation of injectable fluconazole in the treatment of deep mycosis associated with hematological malignancy].
Topics: Acute Disease; Adolescent; Adult; Aged; Antifungal Agents; Candida; Candidiasis; Drug Evaluation; Dr | 1989 |