fluconazole has been researched along with AIDS-Related Complex in 3 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
AIDS-Related Complex: A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating AIDS-related complex (ARC) from AIDS include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in AIDS; follicular or mixed hyperplasia in ARC lymph nodes, leading to lymphocyte degeneration and depletion more typical of AIDS; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown AIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fluconazole 50 mg daily for 14-28 days was effective in the treatment of patients with AIDS and AIDS-related complex with severe oropharyngeal and oesophageal candidiasis." | 9.06 | Once-weekly fluconazole to prevent recurrence of oropharyngeal candidiasis in patients with AIDS and AIDS-related complex: a double-blind placebo-controlled study. ( Dunbar, EM; Ellis, ME; Leen, CL; Mandal, BK, 1990) |
| "Fluconazole 50 mg daily for 14-28 days was effective in the treatment of patients with AIDS and AIDS-related complex with severe oropharyngeal and oesophageal candidiasis." | 5.06 | Once-weekly fluconazole to prevent recurrence of oropharyngeal candidiasis in patients with AIDS and AIDS-related complex: a double-blind placebo-controlled study. ( Dunbar, EM; Ellis, ME; Leen, CL; Mandal, BK, 1990) |
| "In a randomised, double-blind study the efficacy and toxicity of oral fluconazole 50 mg daily and ketoconazole 200 mg daily were compared for the treatment of oropharyngeal candidiasis in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC)." | 5.06 | Comparison of fluconazole and ketoconazole for oropharyngeal candidiasis in AIDS. ( Clumeck, N; De Wit, S; Goossens, H; Weerts, D, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stevens, DA | 1 |
| Greene, SI | 1 |
| Lang, OS | 1 |
| Leen, CL | 1 |
| Dunbar, EM | 1 |
| Ellis, ME | 1 |
| Mandal, BK | 1 |
| De Wit, S | 1 |
| Weerts, D | 1 |
| Goossens, H | 1 |
| Clumeck, N | 1 |
3 trials available for fluconazole and AIDS-Related Complex
| Article | Year |
|---|---|
Thrush can be prevented in patients with acquired immunodeficiency syndrome and the acquired immunodeficiency syndrome-related complex. Randomized, double-blind, placebo-controlled study of 100-mg oral fluconazole daily.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Aged; AIDS-Related Complex; Candidi | 1991 |
Once-weekly fluconazole to prevent recurrence of oropharyngeal candidiasis in patients with AIDS and AIDS-related complex: a double-blind placebo-controlled study.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Candidiasis, Oral; Clinical Trials | 1990 |
Comparison of fluconazole and ketoconazole for oropharyngeal candidiasis in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Aged; AIDS-Related Complex; Candidi | 1989 |