Page last updated: 2024-11-06

floxuridine and Vaccinia

floxuridine has been researched along with Vaccinia in 4 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Vaccinia: The cutaneous and occasional systemic reactions associated with vaccination using smallpox (variola) vaccine.

Research Excerpts

ExcerptRelevanceReference
"Antiviral activities and nucleoside metabolism were determined in C127I mouse, LLC-MK2 monkey, and A549 human cells infected with thymidine-kinase-containing and -deficient (TK+ and TK-) vaccinia (WR strain) viruses."7.74Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus. ( Barnard, DL; Humphreys, DE; Hurst, BL; Smee, DF, 2008)
"Antiviral activities and nucleoside metabolism were determined in C127I mouse, LLC-MK2 monkey, and A549 human cells infected with thymidine-kinase-containing and -deficient (TK+ and TK-) vaccinia (WR strain) viruses."3.74Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus. ( Barnard, DL; Humphreys, DE; Hurst, BL; Smee, DF, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smee, DF1
Humphreys, DE1
Hurst, BL1
Barnard, DL1
SHATKIN, AJ1
KIT, S1
PIEKARSKI, LJ1
DUBBS, DR1
Calabresi, P1

Other Studies

4 other studies available for floxuridine and Vaccinia

ArticleYear
Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus.
    Antiviral chemistry & chemotherapy, 2008, Volume: 19, Issue:1

    Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line, Tumor; Chlorocebus aethiops; Deoxyuridine;

2008
The formation of vaccinia virus protein in the presence of 5-fluorodeoxyuridine.
    Virology, 1963, Volume: 20

    Topics: Floxuridine; Vaccinia; Vaccinia virus; Viral Proteins

1963
EFFECTS OF 5-FLUOROURACIL, ACTINOMYCIN D AND MITOMYCIN C ON THE INDUCTION OF THYMIDINE KINASE BY VACCINIA-INFECTED L-CELLS.
    Journal of molecular biology, 1963, Volume: 7

    Topics: Dactinomycin; DNA; DNA, Viral; Enzyme Inhibitors; Floxuridine; Fluorouracil; Metabolism; Mice; Mitom

1963
Clinical studies with systemic administration of antimetabolites of pyrimidine nucleosides in viral infections.
    Annals of the New York Academy of Sciences, 1965, Jul-30, Volume: 130, Issue:1

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Antimetabolites; Cytarabine; Female; Floxuridine; Gangrene; He

1965