floxuridine has been researched along with Uterine Neoplasms in 10 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Uterine Neoplasms: Tumors or cancer of the UTERUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The antitumor and anti-angiogenic effects of metronomic doxifluridine (delivered via oral gavage) in combination with TNP-470 were evaluated in vivo." | 5.37 | Metronomic doxifluridine chemotherapy combined with the anti-angiogenic agent TNP-470 inhibits the growth of human uterine carcinosarcoma xenografts. ( Choijamts, B; Emoto, M; Kawarabayashi, T; Miyamoto, S; Naganuma, Y; Nakajima, K; Ogata, S; Shirota, K, 2011) |
| "Treatment of choriocarcinoma cells (JAr line) for 24 hr with methotrexate, fluorodeoxyuridine, 1-beta-D-arabinofuranosylcytosine, or hydroxyurea, in doses that inhibit DNA synthesis, results in a 2." | 3.66 | Stimulation of human chorionic gonadotropin by JAr line choriocarcinoma after inhibition of DNA synthesis. ( Azizkhan, JC; Goode, D; Speeg, KV; Stromberg, K, 1979) |
| "Chemotherapy is typically used to treat choriocarcinoma." | 1.46 | CLIC1 Induces Drug Resistance in Human Choriocarcinoma Through Positive Regulation of MRP1. ( Wang, D; Wu, J, 2017) |
| " The antitumor and anti-angiogenic effects of metronomic doxifluridine (delivered via oral gavage) in combination with TNP-470 were evaluated in vivo." | 1.37 | Metronomic doxifluridine chemotherapy combined with the anti-angiogenic agent TNP-470 inhibits the growth of human uterine carcinosarcoma xenografts. ( Choijamts, B; Emoto, M; Kawarabayashi, T; Miyamoto, S; Naganuma, Y; Nakajima, K; Ogata, S; Shirota, K, 2011) |
| "Spinal canal metastasis secondary to gestational trophoblastic neoplasia (GTN) is a rare condition." | 1.35 | Metastasis of gestational trophoblastic neoplasia to the spinal canal: a case report. ( Cao, Y; Feng, F; Xiang, Y, 2009) |
| "We found that this conversion in human tumors was catalyzed not by uridine phosphorylase but by thymidine phosphorylase." | 1.27 | [5'-Deoxy-5-fluorouridine enzymatic activation from the masked compound to 5-fluorouracil in human malignant tissues]. ( Hara, Y, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, J | 1 |
| Wang, D | 1 |
| Feng, F | 1 |
| Xiang, Y | 3 |
| Cao, Y | 1 |
| Naganuma, Y | 1 |
| Choijamts, B | 1 |
| Shirota, K | 1 |
| Nakajima, K | 1 |
| Ogata, S | 1 |
| Miyamoto, S | 1 |
| Kawarabayashi, T | 1 |
| Emoto, M | 1 |
| Wan, XR | 1 |
| Yang, XY | 1 |
| Wu, Y | 2 |
| Yang, YM | 1 |
| Yin, SJ | 1 |
| Li, J | 2 |
| Wan, X | 1 |
| Yang, X | 1 |
| Yang, Y | 1 |
| Ying, S | 1 |
| Malet-Martino, MC | 1 |
| Martino, R | 1 |
| Lopez, A | 1 |
| Béteille, JP | 1 |
| Bon, M | 1 |
| Bernadou, J | 1 |
| Armand, JP | 1 |
| Hara, Y | 1 |
| Matsumoto, S | 1 |
| Mashiba, H | 1 |
| Okamoto, K | 1 |
| Ekimoto, H | 1 |
| Azizkhan, JC | 1 |
| Speeg, KV | 1 |
| Stromberg, K | 1 |
| Goode, D | 1 |
| Dendy, PP | 1 |
1 trial available for floxuridine and Uterine Neoplasms
| Article | Year |
|---|---|
Floxuridine-containing regimens in the treatment of gestational trophoblastic tumor.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Fe | 2004 |
9 other studies available for floxuridine and Uterine Neoplasms
| Article | Year |
|---|---|
CLIC1 Induces Drug Resistance in Human Choriocarcinoma Through Positive Regulation of MRP1.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Chloride Channels; Choriocarcinoma; Drug | 2017 |
Metastasis of gestational trophoblastic neoplasia to the spinal canal: a case report.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta | 2009 |
Metronomic doxifluridine chemotherapy combined with the anti-angiogenic agent TNP-470 inhibits the growth of human uterine carcinosarcoma xenografts.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinosarcoma; Ce | 2011 |
[Floxuridine-containing regime in the treatment of gestational trophoblastic tumor].
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; | 2003 |
New approach to metabolism of 5'-deoxy-5-fluorouridine in humans with fluorine-19 NMR.
Topics: Antineoplastic Agents; Female; Floxuridine; Fluorine; Humans; Kinetics; Lung Neoplasms; Magnetic Res | 1984 |
[5'-Deoxy-5-fluorouridine enzymatic activation from the masked compound to 5-fluorouracil in human malignant tissues].
Topics: Administration, Oral; Aged; Animals; Antineoplastic Agents; Enzyme Activation; Female; Floxuridine; | 1984 |
[Evaluation of antitumor activity of etoposide administered orally for 21 consecutive days against human uterine cancer subcutaneous and/or orthotopic xenografts in nude mice].
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytoge | 1999 |
Stimulation of human chorionic gonadotropin by JAr line choriocarcinoma after inhibition of DNA synthesis.
Topics: Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cycloheximide; Cytarabine; DNA, Neoplasm; Dose-R | 1979 |
Responses of freshly cultured tumour cells to certain selected chemotherapeutic agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Chlorambucil; Colchicine; Culture Techniques; Cyclophosphamid | 1968 |