floxuridine has been researched along with Stomatitis in 13 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Stomatitis: INFLAMMATION of the soft tissues of the MOUTH, such as MUCOSA; PALATE; GINGIVA; and LIP.
| Excerpt | Relevance | Reference |
|---|---|---|
| "All patients had metastatic colorectal cancer, with adjuvant or palliative chemotherapy given to six patients (22%) on schedule A and 12 patients on schedule B (41%)." | 6.69 | Continuous delivery of venous 5-fluorouracil and arterial 5-fluorodeoxyuridine for hepatic metastases from colorectal cancer: feasibility and tolerance in a randomized phase II trial comparing flat versus chronomodulated infusion. ( Adam, R; Bismuth, H; Dallemagne, B; Focan, C; Focan-Henrard, D; Jasmin, C; Jehaes, C; Kreutz, F; Levi, F; Lobelle, JP; Markiewicz, S; Misset, JL; Weerts, J, 1999) |
| "Six Japanese cancer patients treated with gemcitabine plus cisplatin were examined." | 2.71 | Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin. ( Furuse, J; Hasegawa, R; Ikeda, M; Ishii, H; Kaniwa, N; Kikura-Hanajiri, R; Kim, SR; Okusaka, T; Ozawa, S; Saijo, N; Saito, Y; Sawada, J; Sugiyama, E; Ueno, H; Yamamoto, N; Yonemori, K; Yoshida, T, 2005) |
| "All patients had metastatic colorectal cancer, with adjuvant or palliative chemotherapy given to six patients (22%) on schedule A and 12 patients on schedule B (41%)." | 2.69 | Continuous delivery of venous 5-fluorouracil and arterial 5-fluorodeoxyuridine for hepatic metastases from colorectal cancer: feasibility and tolerance in a randomized phase II trial comparing flat versus chronomodulated infusion. ( Adam, R; Bismuth, H; Dallemagne, B; Focan, C; Focan-Henrard, D; Jasmin, C; Jehaes, C; Kreutz, F; Levi, F; Lobelle, JP; Markiewicz, S; Misset, JL; Weerts, J, 1999) |
| "Stomatitis was severe at high doses of DFUR." | 1.26 | Phase I clinical study with 5'-deoxy-5-fluorouridine, a new fluoropyrimidine derivative. ( Abele, R; Alberto, P; Bollag, W; Germano, G; Heintz, R; Seematter, RJ, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CHAMSY, HM | 1 |
| COOPER, PD | 1 |
| ANSFIELD, FJ | 1 |
| CURRERI, AR | 1 |
| OETTGEN, HF | 1 |
| CLIFFORD, P | 1 |
| CANDLER, P | 1 |
| Yonemori, K | 1 |
| Ueno, H | 1 |
| Okusaka, T | 1 |
| Yamamoto, N | 1 |
| Ikeda, M | 1 |
| Saijo, N | 1 |
| Yoshida, T | 1 |
| Ishii, H | 1 |
| Furuse, J | 1 |
| Sugiyama, E | 1 |
| Kim, SR | 1 |
| Kikura-Hanajiri, R | 1 |
| Hasegawa, R | 1 |
| Saito, Y | 1 |
| Ozawa, S | 1 |
| Kaniwa, N | 1 |
| Sawada, J | 1 |
| Abele, R | 1 |
| Alberto, P | 1 |
| Seematter, RJ | 1 |
| Germano, G | 1 |
| Heintz, R | 1 |
| Bollag, W | 1 |
| Patt, YZ | 1 |
| Mavligit, GM | 1 |
| Chuang, VP | 1 |
| Wallace, S | 1 |
| Johnston, S | 1 |
| Benjamin, RS | 1 |
| Valdivieso, M | 1 |
| Hersh, EM | 1 |
| Levin, RD | 1 |
| Gordon, JH | 1 |
| Vokes, EE | 1 |
| O'Brien, SM | 1 |
| Vogelzang, NJ | 1 |
| Schilsky, RL | 1 |
| Ratain, MJ | 1 |
| Focan, C | 1 |
| Levi, F | 1 |
| Kreutz, F | 1 |
| Focan-Henrard, D | 1 |
| Lobelle, JP | 1 |
| Adam, R | 1 |
| Dallemagne, B | 1 |
| Jehaes, C | 1 |
| Markiewicz, S | 1 |
| Weerts, J | 1 |
| Bismuth, H | 1 |
| Jasmin, C | 1 |
| Misset, JL | 1 |
| Lokich, J | 2 |
| Moore, C | 2 |
| Anderson, N | 2 |
| Bern, M | 2 |
| Wallach, S | 1 |
| Williams, D | 1 |
| Moertel, CG | 1 |
| Reitemeier, RJ | 1 |
| Hahn, RG | 1 |
| DeConti, RC | 1 |
| Kaplan, SR | 1 |
| Papac, RJ | 1 |
| Calabresi, P | 1 |
5 trials available for floxuridine and Stomatitis
| Article | Year |
|---|---|
Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin.
Topics: Aged; Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Cis | 2005 |
Fluorodeoxyuridine with continuous leucovorin infusion. A phase II clinical trial in patients with metastatic colorectal cancer.
Topics: Adult; Aged; Colorectal Neoplasms; Diarrhea; Drug Therapy, Combination; Female; Floxuridine; Humans; | 1993 |
Five-day infusional fluorodeoxyuridine with oral leucovorin and escalating doses of interferon alpha-2b: a phase I study.
Topics: Administration, Oral; Adult; Aged; Cohort Studies; Drug Administration Schedule; Female; Floxuridine | 1993 |
Continuous delivery of venous 5-fluorouracil and arterial 5-fluorodeoxyuridine for hepatic metastases from colorectal cancer: feasibility and tolerance in a randomized phase II trial comparing flat versus chronomodulated infusion.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biological Clocks; Colonic Neoplasms; C | 1999 |
A controlled comparison of 5-fluoro-2'-deoxyuridine therapy administered by rapid intravenous injection and by continuous intravenous infusion.
Topics: Clinical Trials as Topic; Diarrhea; Drug Eruptions; Floxuridine; Humans; Hyperglycemia; Infusions, P | 1967 |
8 other studies available for floxuridine and Stomatitis
| Article | Year |
|---|---|
Indirect evidence for the presence of ribonucleic acid in vesicular stomatitis virions.
Topics: Animals; Floxuridine; Nucleosides; RNA; RNA, Viral; Stomatitis; Tissue Culture Techniques; Vesicular | 1963 |
FURTHER CLINICAL COMPARISON BETWEEN 5-FLUOROURACIL (5-FU) AND 5-FLUORO-2' -DEOXYURIDINE (5-FUDR).
Topics: Brain Neoplasms; Breast Neoplasms; Diarrhea; Floxuridine; Fluorouracil; Geriatrics; Humans; Liver Ne | 1963 |
CONTINUOUS INTRA-ARTERIAL OR INTRAVENOUS INFUSION OF 5-FLUORO-2-DEOXYURIDINE: THERAPEUTIC AND TOXIC EFFECTS.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Chemotherapy, Cancer, Regiona | 1963 |
Phase I clinical study with 5'-deoxy-5-fluorouridine, a new fluoropyrimidine derivative.
Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; | 1982 |
Percutaneous hepatic arterial infusion (HAI) of mitomycin C and floxuridine (FUDR): an effective treatment for metastatic colorectal carcinoma in the liver.
Topics: Adult; Aged; Carcinoembryonic Antigen; Colonic Neoplasms; Female; Floxuridine; Hepatic Artery; Human | 1980 |
Infusion of floxuridine plus etoposide plus cisplatin in human malignancies.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ci | 1991 |
A phase I clinical trial of combined fluoropyrimidines with leucovorin in a 14-day infusion. Demonstration of biochemical modulation.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Drug Admin | 1989 |
Continuous intravenous infusions of 5-fluoro-2'-deoxyuridine in the treatment of solid tumors.
Topics: Breast Neoplasms; Diarrhea; Drug Eruptions; Female; Floxuridine; Gastrointestinal Neoplasms; Hemangi | 1973 |