Page last updated: 2024-11-06

floxuridine and Skin Neoplasms

floxuridine has been researched along with Skin Neoplasms in 18 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Skin Neoplasms: Tumors or cancer of the SKIN.

Research Excerpts

ExcerptRelevanceReference
"A left radical mastectomy was performed on a 53-year-old woman, diagnosed with left inflammatory breast cancer, after local arterial chemotherapy with cyclophosphamide (CPA), doxorubicin and 5-fluorouracil (5-FU)."7.70[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)]. ( Gen, T; Hara, Y; Igarashi, K; Jibiki, M; Kawasaki, T; Kikuchi, M; Kudoh, A; Noguchi, N; Yabata, E, 2000)
"High-dose toremifene therapy (120 mg/day) is useful for the recurrence of receptor-positive breast cancer."3.74[Evaluation of combination therapy of high-dose toremifene and oral chemotherapy]. ( Murakami, S; Yamamoto, Y, 2007)
"A left radical mastectomy was performed on a 53-year-old woman, diagnosed with left inflammatory breast cancer, after local arterial chemotherapy with cyclophosphamide (CPA), doxorubicin and 5-fluorouracil (5-FU)."3.70[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)]. ( Gen, T; Hara, Y; Igarashi, K; Jibiki, M; Kawasaki, T; Kikuchi, M; Kudoh, A; Noguchi, N; Yabata, E, 2000)
"Frequency and distribution of 5-fluorodeoxyuridine (5-FdU) plus caffeine-induced fragile sites on chromosomes of peripheral blood lymphocytes (PBL) from 10 patients with cutaneous melanoma were studied in comparison with 10 PBL samples from normal donors of corresponding sex and age."3.68Enhanced expression of 1p32 and 1p22 fragile sites in lymphocytes in cutaneous malignant melanomas. ( Chebotarev, AN; Demidov, LV; Kirichenko, OP; Kopnin, BP; Mukeria, AF; Sokova, OI, 1992)
"With a diagnosis of advanced breast cancer with skin invasion, she underwent right mastectomy with a free skin graft."1.32Massive mucinous carcinoma of the breast untreated for 6 years. ( Sakaguchi, K; Tsuchie, K; Yoneyama, F, 2003)
"The results of treatment of gastric cancer with docetaxel have scarcely been reported."1.31[A case of multiple skin metastases from gastric cancer successfully treated with docetaxel combined with doxifluridine]. ( Ideguchi, K; Ikeda, Y; Mori, T; Nakagawa, K; Okamoto, K; Sakata, K; Yasumitsu, T, 2002)
" FUdR was found to be chemically toxic in itself to 2 canine tissue culture lines at doses used in the literature to increase 125IUdR uptake."1.27The toxicity of fluorodeoxyuridine when used to increase the uptake of 125I-iododeoxyuridine into tissue culture cells in vitro. ( Holmes, JM, 1983)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's4 (22.22)18.2507
2000's7 (38.89)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mori, T1
Ikeda, Y1
Okamoto, K1
Sakata, K1
Ideguchi, K1
Nakagawa, K1
Yasumitsu, T1
Mader, RM1
Schrolnberger, C1
Rizovski, B1
Brunner, M1
Wenzel, C1
Locker, G1
Eichler, HG1
Mueller, M1
Steger, GG1
Sawada, M1
Ono, Y1
Fukushima, M1
Zimmermann, A1
Walt, H1
Haller, U1
Baas, P1
Klein, SD1
Yoneyama, F1
Tsuchie, K1
Sakaguchi, K1
Murakami, S1
Yamamoto, Y1
Holmes, JM1
Bollag, W1
Hartmann, HR1
Tajima, H1
Matsuki, N1
Takeda, T1
Horichi, H1
Kumaki, T1
Shima, K1
Hara, Y1
Kawasaki, T1
Yabata, E1
Gen, T1
Jibiki, M1
Kudoh, A1
Noguchi, N1
Igarashi, K1
Kikuchi, M1
Jato, JG1
Lake, LM1
Grunden, EE1
Johnson, BM1
Sokova, OI1
Kirichenko, OP1
Mukeria, AF1
Demidov, LV1
Chebotarev, AN1
Kopnin, BP1
Firestone, WM1
FitzGerald, GB1
Wick, MM1
Zhao, L1
Kaneda, T1
Tohnai, I1
Shinoda, T1
Kasuya, Y1
Matsuyama, M1
Komuro, K1
Mitsumori, N1
Iwamoto, K1
Murai, R1
Ishida, T1
Nagasaki, Y1
Hujii, Y1
Amano, R1
Yamazaki, M1
Nagayama, A1
Arata, T1
Tanaka, S1
Southam, CM1
Johnson, FD1
Jacobs, EM1
Sullivan, RD1
Miller, E1

Other Studies

18 other studies available for floxuridine and Skin Neoplasms

ArticleYear
[A case of multiple skin metastases from gastric cancer successfully treated with docetaxel combined with doxifluridine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Administration Schedule; Floxu

2002
Penetration of capecitabine and its metabolites into malignant and healthy tissue of patients with advanced breast cancer.
    International journal of clinical pharmacology and therapeutics, 2002, Volume: 40, Issue:12

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Deoxycytidine

2002
[A case of advanced recurrent breast cancer responding to treatment with weekly docetaxel combined with doxorubicin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Combine

2003
Effects of chlorin-mediated photodynamic therapy combined with fluoropyrimidines in vitro and in a patient.
    Cancer chemotherapy and pharmacology, 2003, Volume: 51, Issue:2

    Topics: Apoptosis; Breast Neoplasms; Carcinoma, Basal Cell; Floxuridine; Fluorouracil; Humans; Male; Mesopor

2003
Massive mucinous carcinoma of the breast untreated for 6 years.
    International journal of clinical oncology, 2003, Volume: 8, Issue:2

    Topics: Adenocarcinoma, Mucinous; Biopsy, Needle; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Floxurid

2003
[Evaluation of combination therapy of high-dose toremifene and oral chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:7

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine

2007
The toxicity of fluorodeoxyuridine when used to increase the uptake of 125I-iododeoxyuridine into tissue culture cells in vitro.
    Journal of comparative pathology, 1983, Volume: 93, Issue:4

    Topics: Animals; Cell Line; Cells; Culture Techniques; Dogs; Floxuridine; Idoxuridine; Iodine Radioisotopes;

1983
Tumor inhibitory effects of a new fluorouracil derivative: 5'-deoxy-5-fluorouridine.
    European journal of cancer, 1980, Volume: 16, Issue:4

    Topics: Animals; Female; Floxuridine; Lethal Dose 50; Lung Neoplasms; Mice; Neoplasms, Experimental; Sarcoma

1980
[A case of cutaneous and brain metastasis of gastric carcinoma, treated effectively by chemotherapy with CDDP, MMC, etoposide and 5'-DFUR].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:15

    Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

1994
[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms;

2000
Effect of deoxyuridine coadministration on toxicity and antitumor activity of fluorouracil and floxuridine.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:6

    Topics: Animals; Antineoplastic Agents; Biological Assay; Deoxyuridine; Drug Combinations; Drug Synergism; F

1975
Enhanced expression of 1p32 and 1p22 fragile sites in lymphocytes in cutaneous malignant melanomas.
    Cancer genetics and cytogenetics, 1992, Volume: 58, Issue:1

    Topics: Adult; Caffeine; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human

1992
A comparison of the effects of antitumor agents upon normal human epidermal keratinocytes and human squamous cell carcinoma.
    The Journal of investigative dermatology, 1990, Volume: 94, Issue:5

    Topics: Carcinoma, Squamous Cell; Cell Division; Cell Line; DNA; DNA, Neoplasm; Floxuridine; Humans; Keratin

1990
[Experimental study relating to the anti-cancer effect of doxifluridine].
    Nihon Gan Chiryo Gakkai shi, 1990, Jun-20, Volume: 25, Issue:6

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Screening Assay

1990
[A case of remission of metastatic gastric cancer lesions in the chest and abdominal wall by 5'-DFUR administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Abdominal Muscles; Adenocarcinoma; Administration, Oral; Antineoplastic Agents; Female; Floxuridine;

1985
Joint oncogenic action of antimetabolites and 3-methylcholanthrene in mice.
    Journal of the National Cancer Institute, 1968, Volume: 40, Issue:3

    Topics: Animals; Antimetabolites; Chloramphenicol; Drug Synergism; Female; Floxuridine; Idoxuridine; Methylc

1968
Chemotherapy of metastatic malignant melanoma. Experience with 73 patients.
    Cancer, 1971, Volume: 27, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Eye Neop

1971
The clinical effects of prolonged intravenous infusion of 5-fluoro-2'-deoxyuridine.
    Cancer research, 1965, Volume: 25, Issue:7

    Topics: Adenoma, Islet Cell; Aged; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Female; Fl

1965